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Best Large Grants for Nonprofit Organizations in Missouri

Find the perfect Large Grants for Nonprofit Organizations in Missouri on Instrumentl. 10,000+ Large Grants for Nonprofit Organizations in Missouri in the United States.

10,000+

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$2.59B

Total funding

$5K

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10,000+ grants
$2.59B total
$5K median

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9,663 Results based on applied filters

Pocket Nurse Scholarship Fund

Pittsburgh Foundation
Private
United States
Approximately US $5,000
The Pocket Nurse Scholarship Fund, established by Pocket Nurse at The Pittsburgh Foundation, provides financial assistance to students pursuing education in Allied Health, Nursing, and Nursing Faculty. This initiative highlights the Foundation's commitment to supporting local students, especially those from marginalized backgrounds, as they strive to achieve their academic and career goals. With a minimum GPA requirement of 3.5, the program aims to empower the next generation of healthcare professionals.
Education - Higher Education Nursing Academic Scholarship Programs

LUNGevity Career Development Award

LUNGevity Foundation Inc
Private
United States
US $100,000 - US $300,000
The LUNGevity Career Development Award supports emerging research leaders focused on lung cancer. It funds innovative projects aimed at enhancing early detection and personalized treatments, including targeted therapies and immunotherapy. With a maximum award of $300,000 over three years, this opportunity is limited to US applicants. The funding is contingent upon annual progress reviews, with the first payment expected after November 1, 2025. This award aims to foster groundbreaking advancements in lung cancer research.
Lung Cancer

R.K. Mellon Family Scholarship/Ligonier Valley Endowment Fund

Pittsburgh Foundation
Private
United States
US $5,000

The Pittsburgh Foundation provides scholarship opportunities for students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four–year universities, graduate schools, and career/technical schools.

R.K. Mellon Family Scholarship/Ligonier Valley Endowment Fund

The R.K. Mellon Family Scholarship/Ligonier Valley Endowment Fund was established at The Pittsburgh Foundation to provide scholarships to students in the Ligonier Valley School District. 

  • Average Award: $5,000
  • Award Type: Single-Year Award
Education - Higher Education Volunteerism & Philanthropy Vocational & Trade Education

Paul J. Baum Fund Scholarship

Pittsburgh Foundation
Private
United States
Unspecified amount
The Paul J. Baum Fund Scholarship, established by The Pittsburgh Foundation, supports college and graduate students pursuing degrees in Music. As one of the oldest community foundations in the U.S., The Pittsburgh Foundation has been dedicated to improving quality of life since 1945. This scholarship opportunity is available to both undergraduate and graduate students who meet eligibility criteria, including a minimum GPA of 2.5 and participation in music programs.
Education - Higher Education Academic Scholarship Programs Music Education

Mary Agnes Powers Scholarship Fund

Pittsburgh Foundation
Private
United States
Approximately US $1,000
The Mary Agnes Powers Scholarship Fund, established by the Pittsburgh Foundation, supports nursing students from several Pennsylvania counties. This scholarship honors Mary Agnes Powers and is awarded based on academic merit, financial need, and enrollment in nursing programs. Eligible candidates must reside in designated counties, maintain a GPA of 3.0 or higher, and be entering their final year of nursing education. The scholarship aims to empower local students in their pursuit of nursing careers.
Education - Higher Education Academic Scholarship Programs Nursing

NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32) (358114)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32) supports rigorous biomedical research training and dissertation research for doctoral candidates in clinical, behavioral, or biomedical sciences. Funded by the NIH, this fellowship aims to enhance research capabilities and knowledge in the field of audiology. Key deadlines for applications include April 8, August 8, and December 8 for the years 2025 to 2027, ensuring timely opportunities for aspiring researchers.
Hearing Disorders & Audiology

Juanita Muller Scholarship

The Columbus Foundation
Private
United States
US $1,000

About Us

Our Mission

To assist donors and others in strengthening and improving our community for the benefit of all its residents.

Our Promise

To help you help others through the most effective philanthropy possible.

Juanita Muller Scholarship

Juanita Muller was widowed in 1949. She reared two sons, Joe, then 14 and Charles, 10, working six days a week in a dress factory. Charles, the provider of this scholarship, was the first in his family to receive a college education, thanks to the Woodward Trustees Foundation in Cincinnati. It provided financial aid in high school and a scholarship to the University of Cincinnati. May the recipients of the scholarship fully appreciate the effort of their single parent and have an impact on the lives of those they touch.

Education - Higher Education Educational Access & Equity Family Services

Richard D. Feldman, M.D. Student and Resident Essay Contest

American Academy of Family Physicians Foundation
Corporate
United States
US $1,000 - US $2,000

American Academy of Family Physicians Foundation

The AAFP Foundation focuses on improving health for everyone, and your support makes an immediate impact on the good work we do—from leadership development and education scholarships to funding social and health care services.

The AAFP Foundation strives to create a sense of belonging through an inclusive environment that embraces the family medicine community by recognizing individual uniqueness and contributions to family medicine.

Richard D. Feldman, M.D. Student and Resident Essay Contest

Each year, the Center for the History of Family Medicine (CHFM) sponsors a contest to encourage medical students and family medicine residents to write scholarly essays relevant to the history of family medicine in the United States. The first-place winner will receive $2,000 and the second-place winner will receive a $1,000 award.

We encourage all to apply and are committed to developing scholarly essays relevant to the history of Family Medicine in the United States by medical students and residents who reflect the rich diversity of the specialty and the patients served.

Family Services Medical Education & Professional Training Primary Health Care

Edward A. and Shirley B. Livi Scholarship Fund

Community Foundation of Western Massachusetts
Private
United States
Up to US $3,000

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds. 

Scholarships are provided for one academic year and are not automatically renewed each year. You can reapply to our program every year you are going to attend college, and the application you submit that year will be considered for all scholarships for which you are eligible.

Edward A. and Shirley B. Livi Scholarship Fund

To support residents of Franklin, Hampden and Hampshire Counties who are pursuing fine or performing arts beyond their college freshman year.

Additional Guidelines

  • Students can receive up to $3,000 in scholarships from the Community Foundation.
  • Scholarship awards could impact the financial aid offered by a college, and students are advised to check with their college financial aid offices about this.
  • Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. Some part and/or all the award could be considered taxable income. It is advisable students check with the college or tax accountant regarding this matter.
Education - Higher Education Performing Arts Fine Art

Talati Family Scholarship Fund

Community Foundation of Western Massachusetts
Private
United States
Up to US $3,000
The Talati Family Scholarship Fund, administered by the Community Foundation of Western Massachusetts, aims to support students of color pursuing higher education. Students can apply through a single online application, which connects them to various scholarships based on eligibility. Awards can reach up to $3,000 and may impact financial aid offers. This scholarship is available to undergraduate and graduate students attending accredited institutions in the U.S., particularly those from Franklin, Hampshire, and Hampden Counties.
Education - Higher Education Academic Scholarship Programs Black American Services

Friends of NRA: Capital Improvement Grants

Friends of NRA
Association/Society
United States
Unspecified amount

Friends of NRA

Friends of NRA is the National Rifle Association’s premier fundraising program, supporting the future of shooting sports. Since day one, Friends of NRA has been a 100% grassroots effort fueled by a united front to secure the Second Amendment and raise money for the shooting sports.

Committee volunteers are appointed to State Fund Committees to make recommendations for local grant funding in areas such as youth education, women-focused clinics, law enforcement training, hunter safety, range improvement, firearms and marksmanship training and safety. Recognizing the impact American youth has on the future of the shooting sports, State Fund Committees frequently recommend grants for youth programs, allocating the most significant portion of monies to this vital area.

Grant awards fund activities and support programs in the United States to promote firearms and hunting safety, to enhance marksmanship skills of those in the shooting sports, and to educate the public about firearms in their historic, technological and artistic context.

Friends of NRA: Capital Improvement Grants

Any request to support a project that seeks to improve a facility is considered a capital improvement. This includes, but is not limited to:

  • Range improvements
  • Berm improvements
  • Clubhouse/Classroom facility improvements
  • Shelter structures/covered firing lines/pavilions
  • Road improvements
  • Commercial-grade trap machines (see section regarding trap machines, below)
  • Any other permanent improvement to an organization’s property or facility

The Grant Program considers requests for certain trap machines to be a capital improvement to the facility. Specifically, requests for commercial grade trap machines that have a capacity of 300 clays and up.

Sport Shooting Public Infrastructure

John and Evelyn Turnbull Nursing Education Fund

Community Foundation of Western Massachusetts
Private
United States
Up to US $3,000
The John and Evelyn Turnbull Nursing Education Fund, administered by the Community Foundation of Western Massachusetts, provides scholarships of up to $3,000 to residents of Franklin, Hampden, and Hampshire Counties pursuing a Baccalaureate or Master’s degree in Nursing. This fund is aimed at supporting students from diverse backgrounds, ensuring access to education in nursing, and addressing the region's healthcare needs.
Education - Higher Education Academic Scholarship Programs Nursing

HGA Scholarship

Handweavers Guild of America Inc.
Private
Canada, United States
More than US $4,000
The Handweavers Guild of America (HGA) offers scholarships to students in accredited fiber arts programs in the U.S. and Canada. These scholarships, awarded based on artistic and technical excellence rather than financial need, support education in fiber arts, textile research, and conservation. Annually, funds of $4,000 or more are allocated for tuition. Applicants can apply under categories of artistic merit or scholarly research in the textile industry, with only one scholarship awarded per individual per year.
Education - Higher Education Textile & Fiber Arts Academic Scholarship Programs

Ottawa County Community Foundation: The John and Olive Cornellisson Scholarship Fund

Greater Salina Community Foundation
Private
United States
Unspecified amount
The John and Olive Cornellisson Scholarship Fund, managed by the Greater Salina Community Foundation, supports students graduating from USD 239 or 240 high schools pursuing higher education in agriculture or vocational training. Open to high school seniors, current college students, and non-traditional students, the fund emphasizes financial need over GPA. Previous recipients can apply for renewal, ensuring continued support for those striving to advance their education.
Education - Higher Education Vocational & Trade Education Agricultural Education

Jewell County Community Foundation: Fine Arts Future Development (Solomon Valley)

Greater Salina Community Foundation
Private
United States
Unspecified amount
The Jewell County Community Foundation's Fine Arts Future Development program supports high school seniors in the Solomon Valley area, including Mitchell, Cloud, and Jewell Counties, who are pursuing majors in Instrumental Music or Art. This initiative, backed by the Greater Salina Community Foundation, aims to foster creativity and artistic talent among youth, helping them to achieve their educational aspirations through scholarships and community support.
Education - Higher Education Music Art Education

Heartland Community Foundation: Paul and Terrii Bowman Scholarship

Greater Salina Community Foundation
Private
United States
US $1,000

Heartland Community Foundation: Paul and Terrii Bowman Scholarship

Amount

$1,000 minimum; Multiple scholarships may be awarded.

Geographic Limitations:

High school seniors qualified for graduation from a high school in Rooks County, Kansas.

Renewals

  • Recipients are eligible for a one-year automatic renewal by meeting the following criteria:
    • Enrolled in a vocational field at a post-secondary institution.
    • In good academic standing.
Education - Higher Education Vocational & Trade Education Career / College Preparation

Autism Care Today SOS Program

AUTISM CARE TODAY
Private
United States
Up to US $5,000
The Autism Care Today SOS Program is dedicated to providing immediate assistance to families affected by autism across the United States. Established in 2005, this program addresses urgent needs for effective treatments and services for autism spectrum disorders. Unlike typical grant cycles that may take up to 12 weeks, the SOS Program prioritizes those in critical situations, ensuring timely support based on available funding. Eligibility includes a family income below $45,000 and a demonstrated immediate need for treatment.
Autism

Autism Care Today Grant

AUTISM CARE TODAY
Private
United States
Unspecified amount
The Autism Care Today Grant provides vital funding assistance to families affected by Autism Spectrum Disorders across the United States. Since its inception in 2005, it has supported over 1,562 families with more than $1.85 million in grants. The program focuses on enhancing the quality of life for children with autism through various initiatives, including safety measures, assistive technologies, and behavioral therapy funding, while also addressing the unique challenges faced by military families.
Autism

Trumbull Memorial Health Foundation Scholarship

Community Foundation Of Mahoning Valley
Private
United States
Unspecified amount

About Us

Leadership. Collaboration. Impact.

The Community Foundation of the Mahoning Valley helps philanthropists support the causes closest to their heart while connecting local residents to the resources they need for a better quality of life.

Our Mission

To serve as a leader and advocate for strategic philanthropy, partnering with donors to anchor a permanent and growing endowment and making investments in the Mahoning Valley that improve the quality of life for all residents.

Scholarship Opportunities

Your Community, Your Support System

Our community members support hundreds of local students every year through various scholarships facilitated by the Community Foundation of the Mahoning Valley.

Awarded to Trumbull County residents pursuing a health or medical-related degree or certification – including, but not limited to, those in nursing, behavioral health and public health – from an accredited institution.

Education - Higher Education Nursing Medical Education & Professional Training

MyPath - Goldberg Scholarship Fund for MVCAP

Community Foundation Of Mahoning Valley
Private
United States
Unspecified amount

About Us

Leadership. Collaboration. Impact.

The Community Foundation of the Mahoning Valley helps philanthropists support the causes closest to their heart while connecting local residents to the resources they need for a better quality of life.

Our Mission

To serve as a leader and advocate for strategic philanthropy, partnering with donors to anchor a permanent and growing endowment and making investments in the Mahoning Valley that improve the quality of life for all residents.

Scholarship Opportunities

Your Community, Your Support System

Our community members support hundreds of local students every year through various scholarships facilitated by the Community Foundation of the Mahoning Valley.

  • MyPath- Goldberg Scholarship Fund for MVCAP
    • Awarded to Trumbull County or Mahoning County students participating in MyPath programming or advising, with priority given to students who are or have been in foster care. 
Education - Higher Education Child Welfare Services Educational Access & Equity

SVCF: Fine Arts Future Development Higher Education Scholarship

Greater Salina Community Foundation
Private
United States
Unspecified amount

Greater Salina Community Foundation

Our mission is to build permanent endowment funds and meet charitable community needs. The Foundation achieves its mission by:

  • Enabling donors to fulfill their charitable desires
  • Increasing the capacity of nonprofit organizations to fulfill their individual missions
  • Facilitating prudent management and care of funds
  • Promoting community philanthropy through education
  • Providing affiliate services to neighboring communities
  • Meeting needs through grants, scholarships, and pass-through funds

Solomon Valley Community Foundation

Solomon Valley Community Foundation's mission is to be a catalyst for positive change; engaging partners and inspiring local philanthropy. We leverage resources to overcome obstacles, create lasting legacies, and contribute to the strenth of Mitchell County.

Fine Arts Future Development Scholarship

The Fine Arts Future Development Scholarship supports two different areas of study:

  • Higher education for graduating seniors
  • Summer music camp for junior high or high school students

Fine Arts Future Development Higher Education Scholarship

Graduation high school seniors in the Solomon Valley area, including Mitchell, Cloud, and Jewell Counties, that are pursuing a major in Instrumental Music or Art.

Renewals: Scholarship recipients may reapply as part of the total applicant pool. ​

Music Education - Higher Education Art Education

Walker Family Scholarship

Beckley Area Foundation
Private
United States
Unspecified amount

Mission Statement

Beckley Area Foundation exists to inspire and facilitate generous charitable giving that advances our community.

The Beckley Area Foundation is committed to enriching lives and strengthening communities across Southern West Virginia.

Scholarship

Supporting Student Success

The Beckley Area Foundation proudly manages scholarship funds established by individuals, businesses, and organizations dedicated to helping students pursue higher education. Many of these scholarships are tailored for specific schools, fields of study, or graduates from local high schools, while others offer broader opportunities. No matter the path, our scholarships aim to support students from our region as they work toward achieving their educational goals.

Walker Family Scholarship

Eligibility

Graduating Senior from a Raleigh County High School; Pursuing a degree in the arts; 3.0 GPA; Demonstrate both academic merit, and financial need.

Education - Higher Education Art Education Educational Access & Equity

NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional) (357256)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH StrokeNet initiative invites applications for clinical trials and biomarker studies aimed at stroke treatment, recovery, and prevention. This funding opportunity encourages collaborative projects that validate promising interventions and scientific aims within the NIH StrokeNet framework. Key deadlines for submissions span from February 2025 to November 2026, with support provided by the National Coordinating Center and Regional Coordinating Centers to ensure efficient study implementation and participant recruitment.
Stroke

Applied regulatory science research to evaluate and treat cardiotoxicity of oncology therapeutics

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
Unspecified amount
This grant aims to enhance applied regulatory science research for the evaluation and treatment of cardiotoxicity associated with oncology therapeutics. The initiative will facilitate collaboration with the FDA to develop effective methodologies and solutions, ensuring that research outcomes are directly relevant to regulatory decision-making. Key activities include regular communication with funded investigators and a focus on improving detection and management of cardiotoxicity, ultimately leading to impactful publications and presentations.
Cancer / Oncology Drug Safety

Alzheimer's Drug-Development Program (U01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Aging (NIA) is inviting applications for the Alzheimer's Drug-Development Program (U01 Clinical Trial Optional). This initiative seeks to support pre-clinical and early-stage clinical development of innovative drug candidates aimed at preventing Alzheimer's disease or treating its symptoms. The program encourages collaboration among researchers and aims to enhance the therapeutic pipeline for AD through targeted approaches. This notice allows potential applicants time to prepare robust projects.
Dementia & Alzheimer’s Disease

RFP- Strategically Focused Research Network (SFRN) on Earlier Detection and Delaying Progression of Valvular Heart Disease

American Heart Association
Association/Society
United States
Up to US $4,400,000
The American Heart Association (AHA) is launching the RFP for a Strategically Focused Research Network (SFRN) aimed at enhancing the early detection and delaying the progression of valvular heart disease. This initiative seeks collaborative proposals from researchers to address critical questions and advance understanding in this field. With a maximum budget of $4.4 million and a duration of four years, the AHA plans to award at least three grants based on scientific merit and alignment with its mission.
Cardiovascular Diseases & Systems Women's Health

NEI Postbaccalaureate Opportunities in Vision Science (POVS) Research Education Program (R25 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The NEI Postbaccalaureate Opportunities in Vision Science (POVS) Research Education Program aims to enhance the training of a diverse workforce in biomedical research. This NIH-funded initiative focuses on providing intensive, hands-on research experiences for recent college graduates from various backgrounds, preparing them for doctoral programs in biomedical fields. The program encourages participation from individuals without prior research opportunities in vision sciences, fostering a nationally recruited cohort for substantial impact in the field.
Eye Diseases & Disorders Vision Impairment Care & Services

Large Grants for Nonprofit Organizations in Missouri Highlights

Looking for large grants for nonprofit organizations in Missouri?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Missouri recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Missouri

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Large Grants for Nonprofit Organizations in Missouri grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Large Grants for Nonprofit Organizations in Missouri over $25K in average grant size

29 Large Grants for Nonprofit Organizations in Missouri over $50K in average grant size

25 Large Grants for Nonprofit Organizations in Missouri supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in Missouri supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Missouri?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Missouri?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Missouri year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Missouri given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Missouri changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081