Best Large Grants for Nonprofit Organizations in Missouri

The Fort Orange Garden Club Centennial Endowed Scholarship is designed for third- and fourth-year undergraduate or current graduate students majoring in plant sciences, conservation, environmental sciences, or landscape architecture. Scholarship recipients must demonstrate financial need and reside in specific counties in New York, including Albany and Schenectady, fostering academic growth while contributing to environmental stewardship.

The CAPTRUST National Partnership Grant aims to support local and national charities that serve children's needs. Each year, a Charity of Choice is selected, typically receiving a grant of over $100,000, while additional national grants are awarded to organizations aligned with the CCF mission. This initiative represents 40% of the CAPTRUST Community Foundation's annual giving budget, underscoring its commitment to impactful charitable partnerships.

The NFWF's Five Star and Urban Waters Restoration Grant Program aims to enhance community capacity for sustaining local natural resources through financial assistance for diverse partnerships. With approximately $2.5 million available, projects focus on improving water quality, restoring habitats, and engaging underserved communities. By promoting ecological improvements and community outreach, this program seeks to increase access to nature's benefits while addressing environmental hazards. A blend of urban and rural initiatives is expected for effective implementation.

The Frances M. Peacock Scholarship, established in 1994 by the Garden Club of America, supports college seniors and graduate students studying seasonal habitats for endangered native birds in the U.S. With an annual award of $4500, this scholarship aims to promote effective land-management practices. Eligible candidates must be U.S. citizens or permanent residents enrolled in a U.S. institution. Note that international applicants are not eligible for funding due to IRS restrictions.

The Community Forest and Open Space Conservation Program, offered by the USDA Forest Service, aims to support Indian Tribes, local governments, and qualified non-profits in acquiring private forest lands to establish community forests. This competitive grant program focuses on protecting forestland from non-forest uses while enhancing public access and community benefits such as recreation and education. Applications are due by October 13, 2026, requiring coordination with State Foresters or Tribal officials.

United Health Foundation

The United Health Foundation was established by UnitedHealth Group in 1999 as a nonprofit, private foundation dedicated to improving health and healthcare. To date, the United Health Foundation has committed $880 million to programs and communities around the world, including a $100 million commitment to help support the healthcare workforce.

Grants

Our Philanthropic Partnerships

The United Health Foundation partners with local and national organizations to help build healthier communities. We focus on expanding access to care and improving health quality and outcomes by:

• Advancing and supporting the healthcare workforce
• Addressing mental and behavioral health
• Improving maternal and infant health outcomes
• Helping individuals manage chronic conditions

The Innovative Water Infrastructure Workforce Development Grant, offered by the U.S. Environmental Protection Agency (EPA), aims to enhance career pipelines in the water utilities sector. This funding opportunity supports institutions and organizations in expanding access to water utility jobs through apprenticeship, education, and training programs. By fostering collaborations and increasing public awareness, the initiative seeks to address the workforce needs of water systems, contributing to community health and environmental protection.

The Emerging Artist Grant, offered by the Guild of Carillonneurs in North America, supports the next generation of carillonneurs by providing financial assistance for education and professional development. Eligible applicants can receive up to $750 or $2,000 depending on their qualifications, which may be used for tuition, travel, and equipment. This initiative aims to foster talent in the carillon community, ensuring a vibrant future for this unique musical art form.

The Roy and Gloria Dinsdale Foundation, established in 2022, is dedicated to enhancing lives in rural Nebraska, Wyoming, and Colorado through grants exceeding $10,000. It supports nonprofits and government entities focused on food, shelter, healthcare, education, and the arts. The foundation prioritizes local initiatives that enrich communities and improve access to essential services, while maintaining a commitment to assisting veterans, first responders, and individuals with disabilities.

The Assisting Specialty Crop Exports initiative aims to enhance U.S. specialty crop market access by developing low-oxygen storage and packaging systems for tree nuts. By addressing phytosanitary requirements and pest control, the initiative supports producers in maintaining product quality while complying with international standards. This funding opportunity from the Foreign Agricultural Service encourages innovative solutions that can improve export processes and reduce reliance on costly fumigation methods, ultimately benefiting U.S. agribusiness and ensuring competitiveness in global markets.

The Brinker International Charitable Giving Program focuses on giving back to communities through support for kids, hunger, and education. Organizations eligible for funding must be 501c(3) non-profits and submit requests at least six weeks prior to events. The program does not support individuals, political or religious organizations, or explicit discrimination policies. Funding is provided through monetary donations or in-kind contributions like dining certificates.

The Creley Memorial Conservation Grant, established by the St. Louis Audubon Society, supports bird conservation and education projects in the St. Louis region. Funded by a generous family donation, the grant aims to strengthen collaborations and initiate partnerships that promote bird conservation. With an estimated $7,000 available for the 2025 grant cycle, this initiative reflects SLAS's commitment to fostering awareness and understanding of birds and their habitats, helping communities make informed ecological decisions.

The Scaife Family Foundation Grant has been supporting vulnerable community members for nearly 40 years, providing over $180 million in donations to non-profits. The Foundation aims to match organizations with aligned goals, focusing on women and children, addiction prevention, and animal welfare. It offers grants for general operating and program support, prioritizing impactful programs that address societal issues. Notably, the Foundation considers proposals that foster healthy relationships and promote treatment for addiction, enhancing the welfare of both humans and animals.

Singing for Change Grant Program

Singing for Change empowers people to become more self-sufficient.

Singing for Change supports nonprofit organizations that inspire, empower, and equip people to become more self-sufficient.

Our grantees encourage personal growth among people who are marginalized. They care about the community as a whole, as well as promote the belief that collectively, people can bring about positive change and sustainable self-sufficiency through connected, diverse communities.

Most likely to be considered are organizations that keep their overhead low and collaborate with other groups in their community to find innovative ways of solving a common problem.

Singing for Change (aka SFC Charitable Foundation, Inc.) was created by Jimmy Buffett in 1995, and receives one dollar from each ticket Jimmy sells at his shows. We envision a world where nonprofit organizations, large and small, provide compelling opportunities for individuals to discover their power to make a difference. The foundation promotes work on the forefront of social change - helping people and communities become smarter, safer, stronger, healthier, and whole. 

Singing for Change (SFC) partners with progressive, community-based organizations addressing the root causes of social or environmental problems. We recently narrowed our focus to projects designed to promote self-sufficiency. 

Specifically, we look for groups that are: 

• Working to engage individuals in their communities 
• Helping people realize their full potential
• Creating lasting change in the communities they serve

We will fund operating expenses for those organizations that we feel are accomplishing these goals.

Areas Of Interest:

Children and families: Grants are awarded to programs fostering self-sufficiency and stability. Individual therapy is not funded, nor are therapeutic or recreational camps or wish-fulfillment programs.

Disenfranchised groups: SFC defines these groups as people who have been marginalized in society because of their low levels of skill, education or income, people with disabilities, and people who are homeless. 

Grants range in size from $1,000.00 to $10,000.00.

The Disaster Distress Helpline (DDH) offers 24/7 crisis counseling to individuals in the U.S. and its territories facing emotional distress from disasters. Managed by SAMHSA, the helpline aims to enhance and strengthen access to crucial support services year-round, ensuring that those affected by natural or human-caused disasters receive the help they need to mitigate behavioral health impacts.

The Robert E & Evelyn McKee Foundation Grant focuses on charitable purposes, primarily supporting organizations that qualify under 501(c)(3) of the IRS Code. It awards funds in various areas including civic, cultural, education, healthcare, and youth activities. Eligible recipients are local charities and certain selected colleges for scholarships. However, the foundation does not fund other foundations, organizations outside the U.S., or individual financial aid. Awards are guided by IRS minimum requirements.

The Chaney Family Foundation Grants aim to enhance the welfare of children and families while promoting public safety in Barry County, Missouri; Cabell County, West Virginia; and Jackson & Josephine Counties, Oregon. Grants up to $15,000 are available for West Virginia organizations, while those in Oregon and Missouri can apply for up to $10,000, focusing on human services, faith-based programs, and public safety initiatives.

The Edison Scholars Program, sponsored by Edison International, offers $12,500 annually to thirty high school seniors pursuing degrees in STEM fields at accredited U.S. colleges. This renewable scholarship supports students who demonstrate financial need and reside in Southern California Edison’s service territory. Scholars also gain access to a paid summer internship after their first year. Eligible majors include engineering, mathematics, and computer sciences, fostering the next generation of innovators and leaders.

The Fred C. Gloeckner Foundation Research Fund, established in 2024 through a partnership with the American Floral Endowment (AFE), is dedicated to advancing floriculture research and education. With over 120 years of combined funding experience, it supports innovative projects across various fields related to floriculture. Grants are available for substantial research initiatives at U.S. universities and institutions, focusing on outcomes beneficial to the public, while ensuring projects are reviewed annually for renewal.

The Arkansas Audubon Society Trust Grants support conservation, research, and education projects focused on Arkansas bird species and their habitats. Established in 1972, the trust offers grants ranging from $100 to $1200, prioritizing projects within the state but considering broader initiatives as well. Eligible applicants include individuals, students, educators, and nonprofits. Proposals are accepted biannually, with meetings held to discuss funding decisions, fostering a community dedicated to avian conservation.

The Community Foundation of Central Missouri (CFCM) offers the Impact Grant, a $5,000 funding opportunity designed to significantly address critical issues in mid-Missouri. This grant focuses on human capacity development for disadvantaged individuals or arts initiatives. Eligible applicants must be 501(c)(3) organizations based in central Missouri and operational for at least five years. Projects may target equal opportunity, education, and senior services, among others, adapting to community needs over time.

The McInnes Charitable Trust, founded by Sally and John McInnes, aims to support organizations in Colorado focused on animal welfare, children's health, education, and empowerment. The Trust prioritizes funding for exempt organizations under Section 501(c)(3) with a proven track record. It typically does not fund capital improvements or multi-year commitments. By fostering a spirit of generosity, the Trust honors the McInnes family's legacy and commitment to various charitable causes.

The Institutional Challenge Grant aims to foster collaborative research by requiring institutions to adapt their policies and enhance capacities for meaningful partnerships. It encourages applications from diverse leadership teams in youth-serving areas, focusing on addressing inequalities in youth outcomes. The grant outlines four key goals: strengthening partnerships, pursuing a joint research agenda, facilitating institutional change, and enhancing collaborative capacities for producing actionable research evidence.

The NAILBA Charitable Foundation Grant aims to support small, well-managed U.S. charities that assist those in need, particularly children. Grants are available to organizations with backing from a NAILBA member and that meet specific criteria, such as nonsectarian operation and appropriate fiscal accountability. Since its inception in 2002, the foundation has invested in community transformation by funding initiatives that directly engage in beneficial services, thereby enhancing the welfare of underprivileged groups.

The Humanity United Grant focuses on addressing human exploitation and violent conflict through a strategic approach. It emphasizes support for registered charities and initiatives globally, particularly in regions like Asia-Pacific and South Sudan. The grant fosters collaboration among partners to promote human dignity, racial justice, and peacebuilding. Interested organizations are encouraged to align their proposals with the outlined themes and engage with the funder for potential support.

St. Mary's Bank Charitable Foundation Community Support Grants aim to enhance community welfare by providing financial support to nonprofit organizations. With a commitment to 'people helping people' since 1908, the foundation focuses on areas like youth programming, homelessness, and civic support. In 2023 alone, they donated over $200,000 to 190 organizations, reflecting their dedication to improving lives in New Hampshire. They prioritize funding for nonprofits within their service areas, ensuring impactful contributions to local communities.

The AHRQ Health Services Research Demonstration and Dissemination Grants (R18) aim to support innovative health services research that addresses priorities in quality, safety, and effective healthcare delivery. These grants encourage collaboration among various stakeholders, including patients and policymakers, to enhance healthcare practices across diverse settings. Applications are due by 5:00 PM local time of the applicant organization. This initiative fosters improvements in healthcare outcomes and delivery systems.