Best Large Grants for Nonprofit Organizations in Missouri

The UNCF General Scholarship, offered by the United Negro College Fund, provides essential financial support to students enrolled full-time at one of 37 UNCF Member Institutions for the 2024-2025 academic year. This scholarship aims to enhance access to higher education for minority students, helping them thrive and graduate. The application process is designed to create a pool of eligible candidates for various scholarship opportunities, emphasizing the importance of education and community engagement.

The Renee Starks Steed Memorial Scholarship, offered by the United Negro College Fund, supports HBCU students majoring in fashion-related fields. Aimed at sophomores, juniors, and seniors, it emphasizes academic excellence with a minimum GPA of 3.0. This need-based scholarship fosters diversity, prioritizing students of color, and is part of UNCF's broader mission to enhance educational opportunities for underrepresented communities. Applications for the 2025-2026 academic year are now open.

Community Foundation of Northern Nevada

Established in 1998 as a Nevada nonprofit 501(c) 3 Corporation, the Community Foundation of Northern Nevada has distributed more than $200 million in grants and scholarships from over 300 charitable funds to strengthen our Nevada home. 

Scholarship Program

The Community Foundation of Northern Nevada’s Scholarship Program is intended to help students cover the ever-increasing cost of tuition. Some of our scholarships are based on financial need, but others represent an award for achievement. These scholarships typically go to students who have excelled in an academic area or have shown they can balance academics, volunteer work, and extracurricular activities. There are also scholarships designated for students who have overcome adversity, students pursuing degrees in high-need areas, and adult learners outside the traditional college age group. Community Foundation scholarships can help cover tuition, books, and on-campus housing.

Jean Bear Mullins Memorial Scholarship

In honor of our beloved wife and mother, who was lovingly known as Jean Bear to her children, we have started the Jean Bear Mullins Memorial Scholarship to help students from Washoe County who have been accepted to or are currently enrolled in a Physician Assistant program or Medical School program at an accredited college or university nationwide. We are so proud to be able to honor her legacy.

The Edwards Lifesciences Foundation Grants program aims to improve the health of underserved communities by supporting initiatives focused on education, screening, and treatment of cardiovascular disease. The Foundation seeks to enhance care access for patients, promote awareness of heart health, and foster community engagement through volunteer opportunities. By 2025, the goal is to positively impact the lives of 2.5 million patients affected by structural heart issues. The program emphasizes collaboration and innovation in healthcare.

Community Foundation of Northern Nevada

Established in 1998 as a Nevada nonprofit 501(c) 3 Corporation, the Community Foundation of Northern Nevada has distributed more than $200 million in grants and scholarships from over 300 charitable funds to strengthen our Nevada home. 

Scholarship Program

The Community Foundation of Northern Nevada’s Scholarship Program is intended to help students cover the ever-increasing cost of tuition. Some of our scholarships are based on financial need, but others represent an award for achievement. These scholarships typically go to students who have excelled in an academic area or have shown they can balance academics, volunteer work, and extracurricular activities. There are also scholarships designated for students who have overcome adversity, students pursuing degrees in high-need areas, and adult learners outside the traditional college age group. Community Foundation scholarships can help cover tuition, books, and on-campus housing.

Alex Sevcsik Opportunity Scholarship

The Alex Sevcsik Opportunity Scholarship is open to students who are graduating seniors from the Academy of Arts, Careers, and Technology, or students who have received services from the Eddy House. Preference will be for students who are interested in pursuing Business or Automotive Technologies. Qualifying students will be planning to attend any 2- or 4- year college or university, community college, or trade school in or out of state.

NCCF awards more than $530,000 in scholarships a year. Scholarships and awards are made possible by NCCF Funds, established by generous individuals and families. 

Valerie Rose Pinnette Memorial Scholarship Fund

Award Average:

• $1350

Established by Ed and Rosalie Pinnette in memory of their daughter, Valerie. This scholarship is awarded to a graduating high school student who resides in and attends school in NCCF's 20-town service area. Preference is given to students pursuing a degree in environmental sciences.

Bob Brittain Memorial Scholarship/CCHS Alumni Scholarship

Presented by the Columbia City High School Alumni Association

Criteria are the same for a two year degree and four year degree. This scholarship is one-time and non-renewable.

The ideal recipient of this scholarship will be a CCHS graduate who has been actively involved in several extra-curricular activities, major service activities, and have a grade point average reflective of respectable academic growth. This student will have a four year involvement in the activities listed below. This student will also be fully involved in high school classes during the final trimester of the senior year

Dr. John and Mary Martin Scholarship Fund

This fund was established to honor Dr. Martin and Mrs. Martin’s service as educators. The fund shall provide scholarship assistance to support the college-going ambitions of graduating seniors of Grandview High School who aspire to teaching careers in the field of pre-K through grade 12 education. Preference shall be given to students who are underrepresented in their area of focus within the education field; for example, males of color in pre-school or elementary school.

Award

• $1,000

The WITH Foundation's upcoming RFP cycle opens on July 1, 2026, with decisions from the previous cycle made in February 2026. The foundation aims to improve healthcare for adults with developmental disabilities, emphasizing dignity and comprehensive care. Grants of up to $150,000 are available, with research-focused projects eligible for up to $250,000. Priority is given to applicants with 501(c)(3) status, addressing specific needs in healthcare delivery and advocating for systemic change.

A funding opportunity designed to support food security, refugee services, licensed free healthcare clinics and community development organizations in the United States.

Day of Dignity 2026

Day of Dignity creates an opportunity for caring individuals from diverse communities to provide services to their neighbors in need. The Day of Dignity mission is to promote volunteerism, build relationships, and encourage local organizations to have a transformative impact on their unique community. Bookbags, school kits, jackets, and hygiene kits are some of the in-kind items provided by IRUSA to be distributed during Day of Dignity events. A grant is also given to help support the costs of food, entertainment, venue, etc. Free medical care, screenings, and even barber services can be offered out by the host organization at the event. The host organization is responsible for accommodating their community’s needs and reaching out to different services and vendors. The day is an effort to provide basic living essentials, medical care, and connect those in need to support services available to them in the long term.

The Angela and Reginald Goins Endowed Scholarship, offered by the United Negro College Fund, provides vital financial support to full-time undergraduate students attending four-year historically Black colleges and universities (HBCUs). This need-based scholarship aims to assist students who possess a minimum GPA of 3.0 and demonstrate unmet financial need, fostering academic success and leadership among minority students in major urban areas like New York City, Chicago, and Detroit.

Volunteer Challenge Grants

Each year, CVS Health colleagues volunteer thousands of hours at nonprofit organizations in their communities. To help our colleagues lend even more support to the causes they care about, the CVS Health Foundation offers grants for volunteer service. Funded through the Foundation, our Volunteer Challenge Grant program supports nonprofit organizations where our colleagues donate their time, with grants ranging from $150 to $3,000. The more hours our colleagues give — starting with just 10 logged hours — the more support the nonprofit of their choice can receive from the Foundation.

Volunteer Challenge Grants are awarded on behalf of individuals who volunteer 10, 25 or 100 or more hours of service, to teams that volunteer more than 50 hours of service, and to both individuals and teams who fundraise for a charitable run, walk or ride event.

About Community Foundation of South Alabama

Since its inception, the Community Foundation has grown to over 500 funds and awarded over $98 million in grants and scholarships throughout the eight counties of southwest Alabama, improving the lives of many residents in our corner of the world.

We amplify the gifts from generous donors through wise investment, support others in efforts to enhance our community, and lead and collaborate on initiatives which have a broad impact.

Scholarships

The more than 40 scholarship funds at the Foundation were created by generous donors who wanted to help the students in our community achieve a brighter future. We are committed to assisting the most promising students with scholarships for professional certificate programs, two and four-year undergraduate degrees and graduate school. The scholarship funds at the Foundation award grants to high school, community college and university students to be used for tuition, books, and fees.

Steve and Carolyn Perry Scholarship Fund

This scholarship is for an individual pursuing technical training or certification in advanced manufacturing & will support both career training and career advancement training. The applicant must demonstrate that he or she meets the skill requirements of the training or certification program. Financial need is not required but may be taken into consideration. 

The Gibson Foundation, now known as Gibson Gives, is dedicated to enhancing lives through music by supporting 501(c)(3) organizations. Their mission is to inspire and amplify the power of music through guitars for all generations. With a commitment to music education and wellness, Gibson Gives is making a positive impact worldwide, ensuring that music continues to shape the lives of musicians and enrich communities. Donations are reviewed monthly, requiring a minimum of four weeks for processing.

The Harry C. Moore Memorial Scholarship, offered by the Four County Community Foundation, supports high school seniors who have earned a varsity letter in any sport, including Quiz Bowl, and maintain a GPA of 3.00 or higher. Awardees will be honored at the Foundation Scholarship Celebration in May and recognized at their respective high school awards events. This scholarship exemplifies the Foundation's commitment to enhancing educational opportunities for local students.

About Community Foundation of South Alabama

Since its inception, the Community Foundation has grown to over 500 funds and awarded over $98 million in grants and scholarships throughout the eight counties of southwest Alabama, improving the lives of many residents in our corner of the world.

We amplify the gifts from generous donors through wise investment, support others in efforts to enhance our community, and lead and collaborate on initiatives which have a broad impact.

Scholarships

The more than 40 scholarship funds at the Foundation were created by generous donors who wanted to help the students in our community achieve a brighter future. We are committed to assisting the most promising students with scholarships for professional certificate programs, two and four-year undergraduate degrees and graduate school. The scholarship funds at the Foundation award grants to high school, community college and university students to be used for tuition, books, and fees.

Partners for Environmental Progress (PEP) Scholarship

To be eligible, applicants must meet the following criteria: be an owner, employee or dependent of an owner or employee of the local branch/site of a company whose membership in PEP is in good standing at the time of the application, selection & awarding of the scholarship to the applicant. Applicants must currently be enrolled at the time of the application as a full or part-time student in a two year or four year accredited technical college, or university for secondary or post-secondary work and have a minimum 3.0 GPA with a declared course of study and major in one of the following: environmental science, environmental planning, environmental engineering, or other related science fields of study, including, but not limited to, all engineering fields, marine science, geoscience, fisheries science, forestry, and estuarine science and management.

The monetary value of each scholarship award varies depending upon the amount available in each individual scholarship fund. Scholarship award amounts range from $1,000 - $5,000 for a single year.

The Orlo M. Kintz and Stanley M. Kintz Memorial Scholarship Endowment

The Orlo M. Kintz and Stanley M. Kintz Memorial Scholarship supports outstanding students who demonstrate both academic excellence and dedication to community service.

The Orlo M. Kintz and Stanley M. Kintz Memorial Scholarship Endowment is named after the mother and brother of Rosalie Quesnoy, a passionate educator who taught 7th grade math in Palo Alto, CA. She was a teacher who went the extra mile for her students, and now whose legacy will be carried forward for northern Nevada students pursuing their postsecondary education. This scholarship is designed for students with a high level of academic achievement and community involvement, who plan to attend a school that has a strong program for their chosen major. Students must have a clearly demonstrated financial need. This scholarship is for students who plan to attend a college or technical program that is one, two, or four years. Multi-year scholarships may be awarded. 

The Paul and Barbara Yamber Memorial STEM Scholarship, administered by the Quad Cities Community Foundation, provides need-based financial support for students pursuing STEM fields. Annually, up to $10,000 is awarded, renewable for up to four years. Applicants must demonstrate financial need and a commitment to STEM education, ensuring that this scholarship significantly impacts their ability to attend college. Preference is given to undergraduates, making this a vital resource for aspiring STEM professionals.

Middlesex County Medical Society Foundation

The Middlesex County Medical Society Foundation, founded in 1964 and was initially funded by contributions from the first mass polio vaccination in our county.

MCMS Foundation Scholarship Fund

Middlesex County Medical Society Foundation is an independent nonprofit organization that awards scholarships to deserving students from Middlesex County, New Jersey for the study of medicine. Scholarships are awarded to deserving students who are enrolled in an accredited medical school.

The National Glaucoma Research Program, funded by BrightFocus Foundation, aims to support groundbreaking research in glaucoma. Established in 1978, the program has awarded over $35 million to 32 projects focusing on understanding and treating this disease. The Standard Awards provide $150,000 over two years for researchers with preliminary data to further their work. Eligible institutions must be non-profit and demonstrate their tax-exempt status to receive funding, fostering innovative solutions for glaucoma treatment.

Community Foundation of Northern Nevada

Established in 1998 as a Nevada nonprofit 501(c) 3 Corporation, the Community Foundation of Northern Nevada has distributed more than $200 million in grants and scholarships from over 300 charitable funds to strengthen our Nevada home. 

Scholarship Program

The Community Foundation of Northern Nevada’s Scholarship Program is intended to help students cover the ever-increasing cost of tuition. Some of our scholarships are based on financial need, but others represent an award for achievement. These scholarships typically go to students who have excelled in an academic area or have shown they can balance academics, volunteer work, and extracurricular activities. There are also scholarships designated for students who have overcome adversity, students pursuing degrees in high-need areas, and adult learners outside the traditional college age group. Community Foundation scholarships can help cover tuition, books, and on-campus housing.

Mary J. Yamamoto Memorial Scholarship

The Mary J. Yamamoto Memorial Scholarship helps young women graduating high school seniors from Nevada and Michigan who will be attending accredited colleges, universities, trade schools to obtain a 2 or 4-year degree or certificate. This scholarship is established in memory of Mary J. Yamamoto to support equal access to education. 

The Cancer Center Support Grants (CCSGs) aim to bolster NCI-Designated Cancer Centers by funding comprehensive, clinical, and basic cancer research. These grants facilitate the integration of diverse research capabilities, promoting innovative approaches to cancer prevention, diagnosis, and therapy. CCSGs encourage collaboration among researchers and the development of Shared Resources, ultimately enhancing the understanding of cancer and its treatment. This initiative supports the continuous discovery and dissemination of crucial research findings for community benefit.

Laura Bush 21st Century Librarian Program

Program Overview:

Laura Bush 21st Century Librarian (LB21) projects build a library and archival workforce that can meet the information needs of communities and increase the institutional capacity of libraries, archives, and library and information science graduate programs across the country.  

The program supports projects that:  

• provide training and professional development to library and archives professionals;  
• develop faculty and information leaders; and 
• recruit, educate, and retain the next generation of library and archives professionals. 

Projects can support the recruitment, education, training, and retention of pre-professionals, students, faculty, and the current library and archives workforce. 

Project Type

Planning:

Laura Bush 21st Century Librarian Program

Program Overview:

Laura Bush 21st Century Librarian (LB21) projects build a library and archival workforce that can meet the information needs of communities and increase the institutional capacity of libraries, archives, and library and information science graduate programs across the country.  

The program supports projects that:  

• provide training and professional development to library and archives professionals;  
• develop faculty and information leaders; and 
• recruit, educate, and retain the next generation of library and archives professionals. 

Projects can support the recruitment, education, training, and retention of pre-professionals, students, faculty, and the current library and archives workforce. 

Project Type

Forum:

Family Medicine Cares USA offers grants up to $25,000 to support the establishment of new free clinics. Eligible applicants must either have opened or plan to open within six months of the application deadline and hold the National Association of Free and Charitable Clinics Seal of Excellence. Priority is given to clinics with an AAFP member as medical director and those engaging Family Medicine residents or medical students as volunteers. Applications are accepted annually from March 15 to July 15.

The CDC's NCIPC is seeking research proposals to tackle implementation challenges in providing linkage to care services for individuals with opioid use disorder (OUD). This initiative encourages partnerships with public health entities and local healthcare champions to create actionable, evidence-based strategies. The goal is to enhance care access and ensure comprehensive overdose prevention services are available in real-world healthcare settings, thereby improving outcomes for those at risk of opioid overdose.

Laura Bush 21st Century Librarian Program

Program Overview:

Laura Bush 21st Century Librarian (LB21) projects build a library and archival workforce that can meet the information needs of communities and increase the institutional capacity of libraries, archives, and library and information science graduate programs across the country.  

The program supports projects that:  

• provide training and professional development to library and archives professionals;  
• develop faculty and information leaders; and 
• recruit, educate, and retain the next generation of library and archives professionals. 

Projects can support the recruitment, education, training, and retention of pre-professionals, students, faculty, and the current library and archives workforce. 

Project Type

Community-Centered Implementation