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Best Large Grants for Nonprofit Organizations in Missouri

Find the perfect Large Grants for Nonprofit Organizations in Missouri on Instrumentl. 10,000+ Large Grants for Nonprofit Organizations in Missouri in the United States.

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$2.59B

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$5K

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10,000+ grants
$2.59B total
$5K median

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9,663 Results based on applied filters

Cooperative Education Fund

Cooperative Development Foundation
Private
United States
US $1,000 - US $10,000
The Cooperative Education Fund, managed by the Cooperative Development Foundation, offers grants, scholarships, and sponsorships to support cooperative education initiatives. Annually, it allocates between $100,000 and $140,000, providing 10-15 grants ranging from $1,000 to $10,000. Eligible applicants include cooperatives and related organizations within the U.S. The Fund prioritizes research, educational material development, and sponsorship for educational events, ensuring resources remain accessible and non-proprietary.
Education

AHNS Presidential Award: Understanding Treatment Resistance in Head and Neck Cancer

American Head & Neck Society (AHNS)
Association/Society
Canada, United States
Up to US $10,000
The AHNS Presidential Award supports innovative research focused on understanding treatment resistance in head and neck cancer. With a funding amount of $10,000 for one year, eligible candidates include medical students, residents, and faculty at the associate professor level or below who are AHNS members in good standing. Projects must demonstrate a translational focus and collaboration across disciplines, aiming to yield actionable insights within the award period.
Health & Medicine

ARS Women in Rhinology Research Grant Sponsored by Medtronic

American Rhinologic Society (ARS)
Association/Society
United States
Up to US $25,000
The ARS Women in Rhinology Research Grant, sponsored by Medtronic, offers $25,000 for one year to support innovative research in rhinology. Eligible applicants must be members of the American Rhinologic Society who have completed their residency, with at least one female investigator involved. The award covers legitimate research costs, with a detailed budget required. Results must be presented at an ARS national meeting, acknowledging the grant's support. This initiative fosters women's contributions to rhinology research.
Health & Medicine

Rescue Grant Program

Oxbow Animal Health
Corporate
Canada, United States
Up to US $25,000
The Oxbow Rescue Grant Program supports animal rescue organizations by providing financial assistance for various projects, including education, outreach, capital improvements, and operational support. With annual funding of approximately $25,000, grants are available to qualified groups that benefit small animals such as rabbits and guinea pigs. Oxbow aims to empower these organizations by offering resources and support to enhance their rescue efforts throughout the year.
Animal Welfare - General

The Loris and Merle Coe Scholarship Fund

Stark Community Foundation
Private
United States
More than US $500

Stark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.

The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties. In 2025, more than $1,000,000 was awarded to local students to help them achieve their educational dreams.

The Loris and Merle Coe Scholarship Fund

The Loris and Merle Coe Scholarship Fund assists graduating seniors (including home-schooled students) accepted to any two or four-year college or university who are either a Boy Scout or Girl Scout and have earned either an Eagle Scout Award or rank of Life Scout, Gold Award or Silver Award. 

Amount:

  • Varies. Minimum $500

Renewable:

  • Yes
Mathematics Science

AWI Implementing Refinement Grant

Animal Welfare Institute
Private
Canada, United States
Up to US $8,000
The AWI Implementing Refinement Grant, offered by the Animal Welfare Institute, aims to enhance the welfare of animals in experimentation. Grants up to $8,000 support equipment purchases or staff training for implementing proven refinements. Eligible applicants must be from the U.S. or Canada, and projects should be completed within a year. The grant focuses on improving animal lives beyond basic needs, ensuring no funds are misused for indirect costs or basic care.
Animal Welfare - General

ASPCA Research Grants

American Society for the Prevention of Cruelty to Animals (ASPCA)
Private
United States
US $35,000 - US $50,000
The ASPCA Research Grants support innovative research aimed at enhancing animal welfare. With a total funding amount of $440,000, the grants are open to various research areas including cruelty research, access to veterinary care, applied behavior, psychological trauma, and farm animal welfare. Eligible applicants include U.S. public or private entities and Canadian universities. The maximum individual grant amounts vary by research area, encouraging impactful studies that directly benefit animals.
Animal Welfare - General

Edith J Goode Residuary Trust Grant (Additional Locations)

Edith J. Goode Residuary Trust
Private
United States
Unspecified amount
The Edith J. Goode Residuary Trust Grant supports organizations focused on preventing cruelty to animals. Letters of inquiry are accepted from February 1 to May 1, leading to a formal application process for selected organizations. The 2024 focus areas include programs assisting pets of unhoused populations, domestic violence assistance that allows caretakers and animals to leave together, and parrot rescues. Grants are one-time awards based on organizational fit with donor intent and social impact.
Animal Welfare - General

PLTW Computer Science - New Program (Caterpillar Foundation)

Project Lead The Way Inc
Private
Bexar County, Texas, Cass County, North Dakota +22 more
US $20,000
The PLTW Computer Science program, supported by the Caterpillar Foundation, aims to enhance STEM education in underserved communities. Grants of $20,000 will be awarded to public and charter schools to implement PLTW Computer Science courses over two academic years. This initiative focuses on building workforce readiness and ensuring students gain essential skills in a rapidly evolving job market, thereby creating opportunities for future success.
Computer Science & Engineering

George William Groh Trust Grant

Groh George W Tr FBO Med Research
Private
United States
US $11,500
The George William Groh Trust Grant supports medical research initiatives by providing funding to organizations that qualify as exempt under Section 501(c)(3) of the Internal Revenue Code. Applications are accepted year-round, with a deadline of May 1 for consideration at the annual grant meeting. The foundation aims to enhance medical research efforts and contribute to advancements in healthcare.
Health & Medicine

AAG Award for Community College Program Excellence

American Association of Geographers
Association/Society
United States
Unspecified amount
The AAG Award for Community College Program Excellence honors outstanding non-Ph.D. granting Geography programs in the U.S. It recognizes departments that have significantly enhanced Geography's prominence and reputation. Eligible programs include those offering associate, baccalaureate, or master-level degrees. The award focuses on compelling vision, pedagogical innovation, student mentorship, and promoting diversity. Nominations are carefully evaluated to ensure fair recognition of each program's unique contributions to the discipline.
Geography

Stanley Smith Horticultural Trust Grant

Stanley Smith Horticultural Trust
Private
Australia and New Zealand, Caribbean +3 more
Up to US $25,000
The Stanley Smith Horticultural Trust Grant supports education and research in ornamental horticulture, funding projects that enhance public gardens, promote ornamental plants, and support related educational initiatives. Grants typically range up to $20,000, with a maximum of $25,000, focusing on project support rather than general operating expenses. Eligible organizations include 501(c)(3) public charities and similar entities worldwide, while the Trust does not fund individuals or capital campaigns.
Horticulture & Gardening

APA: Nicholas Rescher Prize

American Philosophical Association Inc
Private
United States
Up to US $2,000

APA Mission Statement

The American Philosophical Association promotes the discipline and profession of philosophy, both within the academy and in the public arena. The APA supports the professional development of philosophers at all levels and works to foster greater understanding and appreciation of the value of philosophical inquiry.

APA: Nicholas Rescher Prize

The Prize winner will receive a $1,000 award upon delivering the prize lecture. If travel funding presents a financial hardship to the selected winner, and if funds in the Prize endowment are, in the APA’s sole discretion, sufficient to do so, up to $1,000 in travel funding may be provided.

The Nicholas Rescher Prize Lecture will be published in the Proceedings and Addresses of the American Philosophical Association or any other publication where the APA regularly publishes the other prize lectures. The Nicholas Rescher Prize winner will be recognized by a letter and certificate from the APA, the usual APA announcement of prizes, and appropriate recognition in an APA prize reception.

Nature of the Prize

Winners of the Prize will have made substantial, outstanding contributions to systematic metaphysics, broadly construed, during the course of their careers. The Prize winner must agree to present a lecture (to be named “The Nicholas Rescher Prize Lecture”) on a topic in systematic metaphysics, broadly construed; the lecture should be accessible to a broad philosophical audience. The lecture will be presented at an APA divisional meeting, normally a meeting within one year following the selection of the Prize winner. The lecture will be presented biennially, and will rotate among the divisional meetings on a regular schedule set by the APA.

Nominations

Any APA member may nominate any other APA member for the Nicholas Rescher Prize; self-nominations are not permitted. Nominations must include a brief statement of support from the nominator.

Only members may submit nominations; please sign in to access the nomination form.

To submit a nomination, fill out the nomination form.

Selection Process

The selection committee may provide additional nominees for the Prize during the selection process. Members of the selection committee are appointed by a process determined by the APA, in its sole discretion, consistent with other prizes the association awards.

Award

  • Frequency: Every other year in odd years
  • Next Award: 2029
  • Next Deadline: April 20th, 2028

Philosophy

Dwight Nicholson Medal for Outreach

American Physical Society (APS)
Private
United States
US $3,000

Dwight Nicholson Medal for Outreach

This award recognizes the humanitarian aspect of physics and physicists created through public lectures and public media, teaching, research, or science related activities. Recognition consists of a stipend of $3,000, Nicholson medal, and a certificate which includes the citation for which the recipient has been recognized. Up to $1,500 will be available for the recipient's travel expenses to the meeting at which the Medal is presented. It will be presented annually.

Physics

PLTW Computer Science - Program Expansion (Caterpillar Foundation)

Project Lead The Way Inc
Private
Bexar County, Texas, Cass County, North Dakota +22 more
US $10,000
The PLTW Computer Science - Program Expansion grant, funded by the Caterpillar Foundation, aims to enhance STEM education in underserved communities. This initiative focuses on expanding existing PLTW Computer Science programs by adding courses, class periods, and training teachers for the 2025-2026 academic year. The grant prioritizes schools with a significant high-need student population, promoting workforce readiness and equipping students with essential skills for a changing world.
Computer Science & Engineering

Darrel Hess Community College Geography Scholarship

American Association of Geographers
Association/Society
United States
US $1,500
The Darrel Hess Community College Geography Scholarship, funded by the American Association of Geographers, supports community college students pursuing geography. Eligible applicants must be enrolled in a US community college and have completed two transfer courses in geography, intending to transfer to a four-year institution. The award includes funding for educational expenses and a certificate of merit, announced at the annual AAG meeting. Compliance with the AAG Professional Conduct Policy is required.
Geography

DNP Registration Reimbursement Grant

American Physical Society (APS)
Private
United States
Unspecified amount

American Physical Society

The American Physical Society is a nonprofit membership organization working to advance physics by fostering a vibrant, inclusive, and global community dedicated to science and society. APS represents more than 50,000 members, including physicists in academia, national laboratories, and industry in the United States and around the world.

DNP Registration Reimbursement Grants Available for the APS Global Physics Summit

DNP is pleased to offer a limited number of registration reimbursement grants to encourage graduate student participation in the annual APS Global Physics Summit. This APS meeting provides an excellent opportunity for students in nuclear physics to present their research, interact with potential employers, and hear about advances in a broad range of physics topics.

If the nominee's application is accepted, the award will cover the early registration fee for students presenting in-person. Students will need to register prior to confirmation of receiving the award.

Physics

Libraries Transform Communities: Engagement Grant

American Library Association (ALA)
Association/Society
American Samoa, Guam +4 more
US $2,000
The Libraries Transform Communities Engagement Grant, provided by the American Library Association, aims to support innovative community engagement projects in libraries. This annual grant awards $2,000 to two selected libraries, focusing on themes of community empowerment. Eligible applicants include various library types in the U.S. and U.S. territories, and projects must demonstrate community collaboration and creativity. Libraries are encouraged to submit proposals that reflect local needs and foster civic participation.
Library Services

R3PEATS Grassroots Rigor Projects: Individual Metascience and Individual Laboratory Capacity-Building (RP1)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The R3PEATS Grassroots Rigor Projects, funded by the NIH, aim to enhance research practices through two project types: Metascience and Laboratory Capacity-Building. Metascience projects focus on creating tools and metrics to promote high-quality research, while Laboratory Capacity-Building projects help labs adopt new techniques and share data that influence research outcomes. This initiative is part of a broader effort to improve rigor, replicability, and reproducibility in scientific research.
Science Emerging Technology Development Nonprofit Growth & Development

AHNS Presidential Award: Novel Therapeutic Targets and Combinations in Head and Neck Cancer

American Head & Neck Society (AHNS)
Association/Society
Canada, United States
Up to US $15,000
The AHNS Presidential Award supports innovative research targeting novel therapeutic approaches in head and neck cancer. With a funding amount of $15,000 for one year, this grant encourages projects that utilize advanced methodologies such as genomics and immune profiling. Applicants must be AHNS members in good standing and provide letters of support from their institution. The goal is to foster research that can lead to significant advancements in treatment strategies for this challenging disease.
Health & Medicine

Enhearten Micro Grant

Enhearten Unseen Leaders
Private
United States
US $500 - US $1,000
Enhearten Micro Grant supports unseen leaders by providing funding for community-driven projects that embody values of humility, integrity, and love. Grants range from $500 to $1,000 and are awarded after a thorough review process. Enhearten aims to empower these leaders, who often lack access to traditional funding sources, by fostering reparative networks that prioritize equality and justice. This initiative seeks to create opportunities for transformative community engagement and support.
Community Development & Revitalization

Baker and Taylor YALSA Conference Grant

American Library Association (ALA)
Association/Society
United States
US $1,000
The Baker and Taylor YALSA Conference Grant provides two $1,000 awards to librarians working with young adults, enabling them to attend the Annual Conference for the first time. One grant supports a school librarian, while the other is for a public library librarian. Applicants must be current members of ALA/YALSA, with prior membership preferred for at least two years, and must have between one to ten years of experience working with teenagers.
Library Services

George and Viola Hoffman Award

American Association of Geographers
Association/Society
United States
Up to US $500

An award from the George and Viola Hoffman Fund may be made annually for student research toward a master’s thesis or doctoral dissertation on a geographical subject in Eastern Europe. Eastern Europe includes the countries of East Central and Southeast Europe from Poland south to Romania, Bulgaria, and the successor states of the former Yugoslavia. Topics may be historical or contemporary, systematic or regional, limited to a small area or comparative.

Geography

ABC-CLIO Leadership Grant

American Library Association (ALA)
Association/Society
United States
Up to US $1,750
The ABC-CLIO Leadership Grant supports AASL Chapters in developing leadership programs for school library associations at various levels. This grant encourages initiatives that engage new members, train current leaders, and foster collaboration among organizations. Successful applications clearly define program objectives, participant groups, and include well-structured budgets and evaluation plans. The grant aims to promote innovative leadership approaches that can be replicated by other chapters, enhancing the overall effectiveness of school libraries.
Library Services

ACS Award in Pure Chemistry

American Chemical Society
Association/Society
United States
Up to US $6,000
The ACS Award in Pure Chemistry recognizes early career researchers for their outstanding contributions to fundamental research in pure chemistry. Established in 1931, the award includes a $5,000 prize and reimbursement for up to $1,000 in travel expenses to the award presentation meeting. Nominees must have less than 10 years of experience since their terminal degree and demonstrate exceptional research merit. Special consideration is given to originality and independence of thought in submitted research.
Chemistry

Toor Scholarship for Strong Public-School Libraries

American Library Association (ALA)
Association/Society
United States
US $1,000
The Toor Scholarship for Strong Public-School Libraries, established by the Toor Family, honors the legacy of Jay and Ruth Toor, who advocated for state-certified librarians in every school. This scholarship supports U.S. public school librarians who create local marketing campaigns to promote their libraries as vital community resources. Each recipient receives a $1,000 stipend to attend the AASL National Conference and must present their project, contributing to the advancement of school librarianship.
Library Services

Scientific Committee on Antarctic Research: Visiting Scholar Awards

The Scientific Committee of Antarctic Research
Association/Society
Argentina, Australia +45 more
Up to US $5,000
The Scientific Committee on Antarctic Research's Visiting Scholar Awards aim to enhance capacity building in underdeveloped Antarctic research programs. Open to scientists and academics with over five years post-PhD experience, the awards support short-term visits (1-4 weeks) to SCAR member countries for training and mentoring. Awards cover international flights and living expenses, promoting long-term research partnerships while considering virtual applications amidst unforeseen circumstances.
Science Humanities & Social Science

Large Grants for Nonprofit Organizations in Missouri Highlights

Looking for large grants for nonprofit organizations in Missouri?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Missouri recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Missouri

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Large Grants for Nonprofit Organizations in Missouri grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Large Grants for Nonprofit Organizations in Missouri over $25K in average grant size

29 Large Grants for Nonprofit Organizations in Missouri over $50K in average grant size

25 Large Grants for Nonprofit Organizations in Missouri supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in Missouri supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Missouri?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Missouri?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Missouri year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Missouri given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Missouri changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081