Best Health and Wellness Grants for Nonprofits in South Carolina

State Farm's Good Neighbor Citizenship Company Grants aim to enhance community safety, development, and education. Focused on long-term impact, they support initiatives in auto and home safety, disaster preparedness, affordable housing, and educational programs. Eligible recipients include nonprofits, educational institutions, and government entities. However, funding is not available for individuals, religious programs, or organizations outside the U.S. By addressing critical community needs, these grants foster safer and more resilient neighborhoods.

The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.

Nonprofit organizations providing health, wellness, education, or community services in South Carolina can apply for funding to support food pantries, healthcare access, STEM programming, and healthy lifestyle initiatives. Labcorp Charitable Foundation provides U.S.-based 501(c)(3) organizations with grants reviewed twice yearly, which may benefit local health and wellness programs serving underserved populations.

Nonprofit organizations, especially accredited charities, can seek funding for humanitarian, social development, science education, community health, and environmental projects, including wellness initiatives in South Carolina. Focused on impactful, sustainable programs, Roche supports high-quality projects that engage local partners and employees, and are managed locally through its affiliate offices within the same country where activities take place.

Nonprofit 501(c)(3) organizations in South Carolina seeking support for charitable, scientific, medical, or educational programs can apply for funding that must be used in the U.S. With a mission to strengthen charitable, scientific, medical, and educational work, Sidney Stern Memorial Trust provides flexible support that may benefit health and wellness initiatives serving broad populations.

The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.

The Robinson Foundation Grant, established in 2016, aims to alleviate hardships faced by individuals and communities, demonstrating God's love through charitable contributions. As a family-operated foundation, it focuses on creating meaningful, long-term impacts in various areas including animal welfare, education, and disaster relief. Organizations eligible for funding must be 501(c)(3) public charities. The foundation prioritizes fiscally responsible projects with the potential for tangible results, while not supporting capital projects.

Nonprofit organizations focused on wellness and healthy living in South Carolina communities served by GALLO Giving can apply for up to US $10,000 to support family well-being, the arts, and overall community health. Grants from Stanislaus Community Foundation prioritize 501(c)(3) organizations in Chester County, South Carolina, that align with these giving priorities.

Nonprofit 501(c)(3) organizations working on community services, environmental conservation, or peacebuilding in South Carolina may be eligible for this flexible program funding. Focused on broad social and environmental impact, the Dudley T Dougherty Foundation invites nonprofits whose work supports wellness and healthy living to apply.

Nonprofit 501(c)(3) organizations, public schools, and qualified local government entities in South Carolina can apply for Georgia-Pacific Foundation’s grants to support education, entrepreneurship, community enrichment, and environmental initiatives. Eligible applicants must be within 30 miles of a Georgia-Pacific manufacturing community and serve communities where the company operates, which may include health and wellness-related programming.

Nonprofit 501(c)(3) organizations, public schools, and libraries in South Carolina seeking support for environmental or human services programs can apply for grants of US $5,000 - US $10,000. With a mission to back environmental and human services work, Lawrence Foundation provides unrestricted operating or program funding, including reasonable indirect costs, for U.S.-headquartered organizations.

South Carolina health and human service 501(c)(3) nonprofits seeking project or capital support can access funding through the Philip L Van Every Foundation; awards range from US $10,000 - US $50,000. Grants prioritize wellness, preventative healthcare, medical education, rehabilitation, and related programs that improve quality of life for residents in North and South Carolina.

Focused on community vitality, Ameriprise Financial invites South Carolina 501(c)(3) nonprofits to apply for grants supporting basic needs, community development, cultural enrichment, and volunteer-driven causes. U.S.-based organizations working on hunger, shelter, financial literacy, workforce readiness, or arts access that can show measurable outcomes and engage Ameriprise volunteers may be eligible.

The Nordstrom Community Grant focuses on supporting youth and families by providing over $1 million in grants annually. It aims to assist grassroots organizations that address essential community needs such as food, shelter, and clothing, as well as creating opportunities for economic mobility through mentorship and workforce development. Eligible organizations must be 501(c)(3) nonprofits located in areas where Nordstrom operates. Applications are encouraged for those meeting these criteria.

Health and wellness nonprofits in South Carolina can seek project funding for education, social services, health care, civic, cultural, and environmental initiatives. Grants from Dr Scholl Foundation help U.S. 501(c)(3) organizations with one-year projects, awarding US $5,000 - US $25,000 through an annual cycle running from October 1 to March 1.

South Carolina health-focused 501(c)(3) nonprofits, government agencies, and tax-exempt educational or research institutions can access funding to improve health outcomes and expand care access for economically vulnerable residents. Blue Cross and Blue Shield of South Carolina Foundation supports projects in areas like oral health, mental health, primary care, and community wellness initiatives statewide.

Nonprofit organizations with a physical location in South Carolina can seek US $1,000 - US $10,000 to support local health, wellness, and education programs, including pediatric cancer services and life skills education. Central Carolina Community Foundation administers the Aflac Charitable Fund Competitive Grant for groups serving designated Midlands counties.

Grants from Spartanburg County Foundation help South Carolina health and wellness nonprofits improve quality of life, educational achievement, and economic mobility for Spartanburg County residents. 501(c)(3) and tax-exempt organizations can request up to US $35,000 for programs such as community health initiatives, mental health services, food access, housing stability, and related support services benefiting Spartanburg County.

Nonprofit organizations in South Carolina working on systems change for economic mobility or housing security can apply for Sisters of Charity Foundation’s Systems Change Grants, with awards of US $15,000 - US $20,000. Funding can support general operations, programs, or capacity-building, and may benefit health and wellness initiatives that address poverty’s root causes.

The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.

Health and wellness nonprofits in South Carolina can receive up to US $50,000 for community-focused programs such as healthcare access, illness prevention, mental health, disabilities, and veteran advocacy. BECU Foundation provides funding to 501(c)(3) organizations with a direct impact in Charleston County, nominated by BECU members who support their work.

The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.

South Carolina health and wellness nonprofits addressing adverse childhood experiences and related trauma can access funding through Amerihealth Caritas Foundation for one-year, project-specific initiatives. Eligible 501(c)(3) organizations in AmeriHealth Caritas Medicaid markets may receive US $100,000 - US $150,000 to improve children’s health, promote protective experiences, and support families in high-Medicaid communities.

South Carolina nonprofits and mission-driven housing organizations with proven affordable housing innovations can access funding through Enterprise Community Partners’ national Housing Affordability Breakthrough Challenge. Grants of US $2,000,000 support ready-to-scale solutions in design and construction, finance, or service delivery that expand affordable rental and homeownership options for low- to moderate-income residents.

Health and human services nonprofits in South Carolina and Eastern Massachusetts can access funding through the Yawkey Foundation’s Program and Small Capital Grants, with awards up to US $100,000 for timebound program needs, small projects, or equipment. Grants prioritize direct services addressing unmet basic needs for vulnerable and underserved individuals and families in Georgetown County and designated Massachusetts counties.

The Mutual of America Foundation Community Partnership Award honors exemplary nonprofit organizations in the U.S. that foster collaborative partnerships across sectors. Annually, a national competition showcases numerous organizations demonstrating impactful community partnerships. Six organizations receive recognition, including the Thomas J. Moran Award, which offers $100,000, and the Frances R. Hesselbein Award, granting $75,000. Since 1996, the award has acknowledged 262 partnerships, emphasizing Mutual of America's commitment to societal improvement through collaboration.

Nonprofit 501(c)(3) and other charitable organizations serving women and children in South Carolina’s Aiken and Edgefield counties can apply for the Community Foundation for the Central Savannah River Area’s Women in Philanthropy Grant. Funding supports high-impact projects in health, social well-being, arts, and education that improve quality of life for local women and children.