Best Large Grants for Nonprofit Organizations in New York

Bristol Myers Squibb Foundation Inc supports independent medical education to enhance healthcare professional competence and improve patient health outcomes. Their mission is to be a global leader in innovative medical education, focusing on evidence-based activities that address critical gaps in knowledge. By fostering excellence in healthcare, they aim to ensure measurable improvements in performance and patient outcomes across various disease areas.

The Growing Justice Fund provides grants ranging from $25,000 to $250,000 to support community-led initiatives that enhance equitable food procurement. This initiative aims to empower Tribal, Indigenous, Black, Latinx, Asian, and immigrant communities by facilitating access to institutional contracts and promoting local economic viability. With a focus on health, environmental justice, and collective action, these grants are designed to foster sustainable food systems and build wealth in historically marginalized communities.

The UNICO Foundation offers the Dr. Benjamin Cottone Memorial Scholarship, providing $5,000 to support a U.S. citizen of Italian descent pursuing a medical degree. Eligible candidates must be seniors at accredited colleges or medical schools, with proof of enrollment required. This scholarship not only aids education but also honors the foundation's commitment to community service and heritage, reflecting the core values of the Italian American community.

The Occupational Safety and Health Training and Education (OSH T&E) Grant, offered by the New York State Department of Labor, provides approximately $5.9 million in funding for safety training programs across New York State. This initiative aims to enhance workplace safety by offering training on toxic substances and the prevention of occupational diseases and injuries. Projects funded under this program will occur between August 1, 2026, and July 31, 2027, promoting safer work environments.

The Liu Shiming Art Foundation provides the Liu Shiming Artist Grants to support artists globally. Eligible applicants must have a degree in studio arts or have held a debut exhibition between 2015 and 2023. The foundation aims to promote understanding of Asian art and culture. Grants of $5,000 total will be awarded in two installments, with notification to successful applicants by December 2, 2025, and the first payment due by January 15, 2026.

Project Lead The Way is offering a rolling grant for schools to implement the PLTW Biomedical Science program for the 2026-2029 academic years. Eligible schools can receive up to $14,000 to cover participation fees and training costs. This grant encourages public, private, and charter schools across the U.S. to enhance their science curriculum, supporting students with engaging, hands-on learning experiences. Schools must commit to offering specific courses during the grant period to qualify for funding.

The F26AS00104 State ANS Management Plan 2026 aims to combat aquatic nuisance species through pre-proposals followed by full applications. Managed by the US Department of the Interior's Fish and Wildlife Service, this initiative requires a 25% cost-share and limits administrative costs to 5%. Applications are due by October 14, 2026, though the funding opportunity closes on December 16, 2026. The plan is crucial for maintaining biodiversity and supporting a coordinated national approach to invasive species management.

Outside Counsel Services

Seeks proposals to provide comprehensive outside counsel legal services to NYSERDA in the subject matter areas of Renewable/Clean/Nuclear Energy Development, Nuclear Energy Regulation, Environmental and Land Use, Public Authorities Advising, Regulatory, Financing, Real Estate, State and Federal Labor Law and Employment Practices, or Cyber Security, Information Technology and Artificial Intelligence.

Selected firms will be expected to act as outside counsel for NYSERDA for a period of five years, with specific matters assigned as the need arises.

The Mid Atlantic Tours Grants program supports presenters in the mid-Atlantic region who engage Roster Artists during their project periods. Eligible presenters can receive up to a 50% subsidy for artist compensation, which includes fees, housing, and travel. The application process is straightforward and non-competitive, but early engagement with the artist's tour manager is advised due to limited funding. This initiative fosters a diverse range of performances and community engagement.

The Folk and Traditional Arts Community Projects Grant, offered by the Mid Atlantic Arts Foundation, supports projects that enhance traditional arts and cultures in the mid-Atlantic region. Non-profit organizations can apply for grants ranging from $1,000 to $5,000, with a required 1:1 match. Eligible activities include performances, workshops, and public art collaborations, particularly those engaging underrepresented communities. This initiative fosters artistic expression and cultural connection across diverse communities.

• Glenn W. Bailey: STEM Scholars Grant
• Glenn W. Bailey Foundation STEM Sprouts
• Glenn W. Bailey Foundation STEM Stars
• Glenn W. Bailey Foundation Teen Tech Competition

Our Mission

Our Mission is to foster pathways to success in globally competitive STEM careers for students in the United States.

We want to help ensure that the United States remains a global thought leader in all forms of science, math, and technology by promoting projects which encourage, enhance and advance STEM education in this country and to promote projects which provide career opportunities for individuals with STEM education backgrounds.

The Foundation, formed in 2022, seeks to give students and educators more resources for developing and participating in STEM-based, hands-on learning. As a Foundation, we want to support STEM education programs that are making a difference for students regardless of their background or resources. We want every student in America to have enough exposure to STEM from an early age and to transform our attitudes around STEM subjects. We are working towards changing the narrative that promotes STEM subjects as challenging and difficult to the idea that a broad knowledge of STEM education is imperative for socioeconomic and economic freedom as an adult, for all.

Programs & Partners

STEM Encouragement 

It all begins with an idea. We support educational opportunities ranging in age from children through post-doctoral candidates and beyond to promote STEM learning and initiatives that seek to increase awareness and success in STEM careers in the United States.

Environmental & Climate

We will support Innovative Environmental Projects (IEPs) that utilize interdisciplinary research to identify and address critical environmental problems with cutting-edge, innovative solutions that are scalable and replicable.

Scientific Research

Contribute to advancements in biomedical research and innovation to accelerate the progress in medical research and drug treatment development - specifically for high-mortality, under-funded areas of need such as pancreatic and colon cancers.

Urban & Community Entrepreneurship

Advancing entrepreneurship in moderate-income and underserved communities to help business leaders of today and tomorrow prosper. The focus of this program is to help foster economic empowerment by investing in organizations focusing on one individual, one job, and one business at a time.

The Mutual Self-Help Housing Technical Assistance Grants in New York provide essential funding to qualified organizations for local self-help housing projects. These grants enable very-low- and low-income families to construct their own homes with guidance and technical assistance. Eligible applicants include government and private non-profit organizations as well as federally recognized tribes. The program fosters community collaboration and provides families with the skills needed to manage their housing construction efforts effectively.

The Tree Campus Higher Education Program, initiated by the Arbor Day Foundation, promotes the integration of trees and green spaces into college campuses. By adhering to five key standards, institutions can achieve national recognition while enhancing the well-being of students and the environment. This program not only fosters community pride but also supports sustainability efforts, making campuses healthier and more beautiful for all. Join the movement to cultivate a greener future through education and active participation.

The Day-End Dough-Nation® Program by Panera Bread exemplifies community generosity through the donation of unsold bakery products to local charities. This impactful initiative supports various organizations that distribute food to those in need, including shelters, health centers, and youth programs. By partnering with thousands of non-profits nationwide, Panera Bread not only reduces food waste but also plays a crucial role in addressing hunger and promoting equality within communities.

The Toy Foundation Program offers a unique opportunity for nonprofit organizations to apply for toy donations to support children in need. The application period runs from January to June, with approved applicants receiving toys by the end of the year. This initiative, part of the Toy Chest program, has positively impacted over 35 million children since 2003, promoting play as essential for emotional and educational development.

The UrbanGlass Visiting Artist and Designer Fellowship offers artists and designers the chance to explore glass as a creative medium. Recipients will receive guidance, access to state-of-the-art studios, and a $15,000 stipend to support their projects. This fellowship encourages collaboration and community engagement, allowing fellows to share their ideas through lectures and hands-on experiences. Ideal for those with minimal glass experience, it promotes diverse voices in the arts while requiring flexible onsite participation.

UrbanGlass provides financial assistance to support students pursuing glass art education. This initiative offers a rolling application process for those demonstrating financial need, enabling access through a Financial Assistance Application or a manageable payment plan. The program aims to reduce barriers and promote inclusivity within the artistic community, ensuring that students at all proficiency levels can engage in hands-on learning and collaboration. However, funding is not guaranteed, emphasizing the importance of equity in education.

The Chelicca Scholarship for Bead Project Alumni, offered by UrbanGlass, provides $1,000 to ten selected alumni to further their creative studies at UrbanGlass. This financial support can be applied toward one class and any remaining balance can be used for studio time. Recipients must accept the award via email within one week of notification. This initiative underscores UrbanGlass's commitment to nurturing artistic talent and promoting the use of glass as a creative medium.

Pincus Family Foundation

PFF is driven by the values that our founders David and Gerry Pincus lived by: “to get involved, not just think about your own life, you are supposed to do things for other people.” Today, the second and third generation of Pincus Family members have added their ethos, while keeping the founders’ legacy alive.

Pincus Family Foundation Grant

Mission Alignment: We support our non-profit partners to develop and enhance programs that improve the lives of children, their families, and their communities.

PFF Funds Projects, Programs, & General Operating Support in Four Priority Areas

Creative & Performing Arts

The Pincus Family Foundation’s Creative and Performing Arts portfolio supports programs where young people use art as a tool to address the structural inequities they face. Five strategic priorities:

• Arts for Social Change Focus – Integrating artistic practice with community organizing, policy advocacy, and/or systemic change efforts
• Hyperlocal Community Integration – Deep community embedment with extensive local partnerships
• Teaching Artist Investment – Commitment to the professional development and well-being of teaching artists
• Cultural Responsiveness – Programming that incorporates community cultural wealth with community input
• Environmental Justice Integration – Authentic integration of environmental themes from community-identified priorities

Target Constituency: Organizations serving preK-12 youth from marginalized communities with arts for social change programming that connects them to the power of art to question and transform systems.

Education

High school readiness for many low-income students, largely is a result of poor preparation in middle school. PFF is funding programs/projects that support middle school engagement and focus on achievement filling a funding gap. 

Target Constituency: We support non-profit organizations serving middle school students who face gaps in comprehensive high school readiness. These organizations implement innovative programming that creates challenging yet nurturing environments—preparing students for achievement while inspiring them to become engaged, confident citizens ready to contribute to their communities.

Health & Wellness

Goal: Advance children’s health and well-being by supporting nonprofits that strengthen social conditions, empower youth, and build healthier environments in marginalized communities.

Target Constituency: Nonprofits whose work strengthens social determinants of health for children in marginalized communities.

Play & Recreation

Goal: Advance children’s social-emotional development and physical well-being by supporting nonprofits that create inclusive play-based programming, competitive sports opportunities, and outdoor recreational experiences in under-resourced communities.

Target Constituency: Non-profits whose work promotes access to quality recreational programming for children ages 6-18 in under-resourced communities.

For all grants, the organization’s mission and scope must align with the Foundation’s mission. For the latter, these grants can be either unrestricted or restricted to a particular program or project. The type of grant and what it is used for will dictate the goals and objectives to be met.

The Northeast Agricultural Education Foundation Grant supports educational and leadership initiatives focused on agriculture within the Northeastern United States. Established as a private foundation, it provides funding to 501(c)(3) organizations that promote agricultural leadership, enhance understanding of food production, and improve farmers' quality of life. The Foundation prioritizes programs that educate youth about agriculture and promote farm safety awareness. Grants are primarily directed towards statewide or larger projects that align with these objectives.

Mission

The Foundation was established in December 2013 by Kathryn B. McQuade, after retiring from 33 years of working in the business community. I was blessed to have been born into a loving middle class family. My father worked very hard to insure that all of his children were given an opportunity for a good education and my mother, “a stay at home Mom’ was always there for us. My world was safe and comfortable. My life is in stark contrast to how much of the rest of the world lives. I continue to read of the terrible injustices waged against women and children globally and hope that this foundation can provide them the opportunity and resources to succeed. We will support organizations that help us achieve our goal of Striving to make sustainable improvements in women and children’s rights education and welfare.

Kathryn McQuade Foundation Grant

The Foundation will make timely decisions on your grant request and provide clear communications on our expectations of reporting progress.

Women

The Foundation’s goal is to provide women assistance and provide them an opportunity to succeed. Assistance can take many forms, however our goal is to help them become self sufficient and enable them to lift themselves out of poverty and provide for their children. Access to education, job training and professional skills, even access to capital in order to build a business are possible ways we will consider helping women to succeed. Grant requests should focus on enabling the women to sustain financial independence.

We look forward to hearing of the many creative ways organizations are working on helping women succeed through out the world. To help women is to help their children and the communities they live in.

Children

Too many children in the US and across the world live in poverty and lack the access to education. Education and/or appropriate skills training are necessary to break the cycle of poverty and crime. While the assistance to women may take many forms, the foundation’s focus for children will target education and/ or skills training. The Foundation is open to many ideas on how to accomplish this goal and look forward to receiving proposals to help all children achieve their potential.

New ERA Writers Program Goals

The New Era Writers Program aims to inspire those who seek to improve their current abilities or find a community with like-minded individuals and writers. We want to provide support and resources to writers and writing programs to help amplify their voices and improve their capabilities. Our Foundation believes that one of the most important life skills is the ability to be an effective writer and communicator. We support programs that will provide anyone with the knowledge and skills to express themselves through the art of writing and encourage higher levels of training designed to assist in delivering clear and persuasive arguments for change and equality. This program was designed to support writers as they pursue a career and love of writing.

Program Outline

The New Era program was created to encourage writing professionals, teachers, counselors, professors, and schools to start or continue programs supporting professional and creative writing career paths.

The program can support:

• Any writing genre: Journalism, Fiction, Poetry, Prose, Blogging, Novel, Autobiography, Book Reviews, Comic Strips, Diaries, Essays, Fables, etc.
• Programs can be Workshops, Writing Clubs, Curriculum Based Programs, After-school programs, Summer Programs, Retreats, etc.
• Program space that provides a safe and inspiring environment.
• Community Partnerships or On-Staff Writing Professionals or Teachers with Writing Degrees or who Minored in Writing or any Humanities, Liberal Arts or another degree that teaches or encourages writing.

The Ashland County Wildlife Conservation League David McClure Memorial Scholarship supports graduating seniors from Ashland County high schools and alternative education programs pursuing a degree in wildlife-related fields. Applicants must maintain a GPA of 3.0 or higher and be accepted into accredited colleges or vocational programs. This scholarship fosters educational growth while promoting conservation efforts, reflecting the commitment of the Ashland County Community Foundation to enhance community development and support future leaders in wildlife conservation.

Office of Victim Services

Mission: OVS has a three-tiered mission to: provide compensation to victims of crime, their family members, and other eligible individuals in a timely, efficient and compassionate manner; fund direct services to victims of crime and their families through a network of programs across New York State; and advocate for the rights and benefits of all victims of crime.

Services

Compensation and Reimbursement

OVS provides substantial financial relief to victims of crime and their families by paying unreimbursed crime-related expenses, including but not limited to: medical and funeral expenses, loss of earnings or support, counseling costs, crime scene clean-up expenses, the cost to repair or replace items of essential personal property, reasonable and necessary court transportation expenses, assistance to crime victims acting as a good Samaritan, the cost of residing at or utilizing the services of a domestic violence shelter, and limited attorney fees.

Victim Compensation

Eligibility for Compensation

Victims of crimes that happen in New York State may be eligible to get reimbursed for certain crime-related, out-of-pocket expenses. New York State residents who are victims of terrorism in other countries may also be eligible.

Eligibility for compensation depends on the type of crime that occurred, and for certain types of crimes, there may be additional age or disability requirements.

Below is a list of the types of compensation OVS can provide:

• Crime-related, out-of-pocket medical and counseling expenses
• Repair or replacement of essential personal property lost, damaged, or destroyed as the direct result of a crime (up to $2,500 total per claim)
• Funeral and burial expenses (up to $12,000)
• Relocation, moving, and storage costs (up to $2,500)
• Lost earnings or loss of support (up to $30,000)
• Lost savings of vulnerable elderly or incompetent persons (up to $30,000)
• Transportation for crime-related medical appointments or necessary court appearances
• Employment-related transportation expenses due to a victim’s crime-related physical injury (up to $2,500)
• Crime scene cleanup expenses and/or cost of securing a crime scene (up to $2,500)
• The cost of residing at or utilizing the services of a domestic violence shelter
• Occupational rehabilitation expenses
• Home and vehicle modifications
• Attorney fees for representation before the agency and/or before an appellate court, upon judicial review of the victim’s OVS claim (up to $1,000)

The Corning Nonprofit Grants program supports community-based initiatives in education, human services, and culture. Eligible nonprofits that align with our criteria may apply for funding on a rolling basis. The application window for invited organizations runs from February 10 to September 15. We emphasize local impact within a 20-mile radius of Corning, NY, ensuring that our contributions foster collective growth and engagement in the community.

The Special Presenter Initiatives Grants, offered by the Mid Atlantic Arts Foundation in partnership with various local arts organizations, aim to support the presentation of professional performing artists at small and mid-size community venues. This initiative encourages projects that feature touring artists and includes community engagement activities, fostering meaningful interactions between artists and local audiences. The program seeks to enhance the cultural landscape of the participating jurisdictions through diverse and innovative performances.

The McKesson Foundation Grant provides funding above $25,000 to support health equity initiatives across North America. Founded in 1943, its mission focuses on removing barriers to quality healthcare for vulnerable communities. The foundation prioritizes projects that align with strategic pillars: reducing cancer burdens, preparing the healthcare workforce, and enhancing crisis response. Eligible organizations include national and local nonprofits. Funding is limited to specific regions and assessed based on demonstrated need and expected impact.