Best Oklahoma City Grants for Nonprofits in Oklahoma

Mesothelioma Applied Research Foundation Inc

The Mesothelioma Applied Research Foundation is the only nonprofit charity organization dedicated to ending mesothelioma, and the suffering caused by this cancer, by:

• funding research to improve treatment options;
• providing treatment support and education for patients and their families;
• and advocating for federal funding of research.

The mission of the Mesothelioma Applied Research Foundation spans across four distinct areas: through research, education, support, and advocacy the Foundation seeks to eradicate the vicious effects of mesothelioma. Led by the Board of Directors, our team works collaboratively to develop and administer our programs, and to fundraise to pay for those programs (the Foundation is funded by private individual and corporate contributions only — it does not receive any government funding).

Patient Travel Grant Program

A mesothelioma diagnosis and treatment often require the patient and their family to incur numerous expenses as part of their treatment. Travel to treatment, alone, can cause a significant financial burden on the patient, which might even cause the patient to not seek treatment away from home, even it’s their best option. To ensure that all patients have the ability to seek specialized help and treatments, the Mesothelioma Applied Research Foundation administers its Travel Grant Program.

The Meso Foundation’s Patient Travel Grant Program, founded by Mary and Bob Cosentino, provides travel grants to patients and one caregiver traveling for an initial consult and/or for clinical trial treatments.

• The type of eligible travel must fall into at least one of these two categories:
  • One trip for one initial consultation with a mesothelioma specialist.
  • Multiple trips to participate in an interventional clinical trial (found on clinicaltrials.gov).

Mesothelioma Applied Research Foundation Inc

The Mesothelioma Applied Research Foundation is the only nonprofit charity organization dedicated to ending mesothelioma, and the suffering caused by this cancer, by:

• funding research to improve treatment options;
• providing treatment support and education for patients and their families;
• and advocating for federal funding of research.

The mission of the Mesothelioma Applied Research Foundation spans across four distinct areas: through research, education, support, and advocacy the Foundation seeks to eradicate the vicious effects of mesothelioma. Led by the Board of Directors, our team works collaboratively to develop and administer our programs, and to fundraise to pay for those programs (the Foundation is funded by private individual and corporate contributions only — it does not receive any government funding).

Bret A. Rosenthal Patient Assistance Fund

Patients diagnosed with cancer at a younger age often face greater financial burdens. This is a time in a patient’s life when they are raising a family, starting a career, or have not accumulated savings. For patients 49 and under, the Foundation administers the Bret A. Rosenthal Patient Assistance Fund grant program. This program is made possible by the generosity of the Rosenthal family.

Utilizing the Full Power of Empire AI Request for Applications

The Simons Foundation (SF) intends to support cutting-edge mathematics and basic science research, drawing on the advanced computational power of the Empire AI.

Toward this goal, SF plans to initiate a new program to fund six to 12 proposals through a competitive open call to the Empire AI research community.

A successful proposal will outline an ambitious two-year research program in one of the following fields, or at their intersections: computational astrophysics and physics, computational biology, mathematics, neuroscience and computational physical chemistry. Each proposal will necessarily rely on the development and utilization of foundational machine learning models, aimed at solving problems of fundamental importance in the above-listed disciplines.

Computational biophysics, neuroscience, ecology and evolution, plant biology, optimal transport, multiscale physics, fluid dynamics and numerical general relativity are representative examples of fields that could use multinode clusters of GPUs of Empire AI, which is a requirement of the program. All submitted proposals should detail how their work will use multinode clusters of GPUs in Empire AI. Proposals focused on data curation and creation of datasets can be considered in exceptional cases, as long as the attained data will be used by the proposers for solving scientific problems as part of the same proposal.

The program’s total budget is expected to be $6 million USD over a two-year period.

Funding

Award Amount: There is no maximum budget total for an individual award. The total amount requested should reflect the proposed research. All award amounts are inclusive of indirect costs (see our grant policies). Please note that we anticipate funding six to 12 applications. The total program’s budget of $6 million USD over two years will be spread across all awards.

Award Duration: June 1, 2027, through May 31, 2029.

Number of Awards: We expect to select six to 12 applications for funding.

The OJJDP FY 2026 Strengthening Internet Crimes Against Children (ICAC) program aims to enhance the technological investigative capacity of ICAC task forces nationwide. Through this funding opportunity, the program will support the development and refinement of investigative tools and methods to combat child sexual abuse material, exploitation, and trafficking. The deadline for application submission is November 5, 2026, at 8:59 p.m. ET, emphasizing the urgency of addressing these critical issues.

The FY 2027 Department of War Multidisciplinary Research Program (MURI) funds U.S. academic teams engaged in innovative basic research addressing future defense challenges. Established in 1985, MURI emphasizes collaboration across multiple scientific disciplines to tackle complex, DoW-relevant issues. By fostering partnerships among faculty, postdoctoral researchers, and students, the program aims to advance the U.S. defense industrial base and nurture a skilled scientific workforce, contributing to significant breakthroughs in military technology and economic growth.

The OJJDP FY 2026 Victims of Child Abuse Act Training and Technical Assistance program aims to enhance the skills of child abuse professionals. This initiative will promote coordinated investigations and improve intervention strategies for child abuse victims. By providing essential training on effective interviewing, investigative techniques, and interagency collaboration, the program seeks to elevate the quality of care and support available to affected children and families. Applications are due by November 5, 2026.

The BJA FY 2026 Rural Violent Crime Reduction Initiative aims to empower local law enforcement in rural areas to combat violent crime effectively. This funding opportunity provides resources for personnel, technology, and data analytics to enhance crime prevention strategies. Eligible applicants can utilize updated equipment and training to address specific violent crime challenges, ensuring safer communities through innovative approaches and strategic resource allocation. Applications are due by November 6, 2026.

The Fiscal Year 2027 Department of War Multidisciplinary Research Program aims to fund innovative research teams from U.S. universities. Established in 1985, this initiative addresses complex challenges faced by the Department of War, fostering collaboration across various scientific disciplines. By integrating world-class faculty and graduate students, the program seeks to cultivate a skilled workforce poised to enhance the U.S. defense capabilities and contribute to the advancement of the defense industrial base.

The State Biomonitoring Cooperative Agreement aims to enhance public health laboratories' ability to conduct biomonitoring and assess human exposure to environmental chemicals. This funding opportunity emphasizes community investigations, state-level studies, and emerging chemicals not covered in the National Exposure Report. By improving laboratory capacity and fostering collaboration, the initiative seeks to identify harmful exposures and evaluate intervention effectiveness over a three-year period.

The National Institute of Neurological Disorders and Stroke (NINDS) is collaborating with other NIH institutes to enhance rigor and replicability in biomedical and behavioral research. This initiative aims to support projects focused on assessing the impact of improved research practices, developing frameworks for study selection, and measuring the generalizability of findings. Currently, applications are not being solicited, allowing researchers time to prepare collaborative proposals.

Oklahoma Department of Commerce

Here at the Department of Commerce, our job is to bring employment, investment, and economic prosperity to the state of Oklahoma. Through dynamic partnerships and innovative collaborations with companies, universities, not-for-profit organizations, and government leaders, we are building a business environment that supports business growth and shared community prosperity.

Community Development Block Grant Programs

The Community Development Block Grant (CDBG) program enables rural Oklahoma communities to finance a variety of public infrastructure and economic improvements and helps promote job growth as a result of these improvements. CDBG funds are provided by the federal government (U.S. Department of Housing and Urban Development) and managed by the Oklahoma Department of Commerce to help ensure Oklahoma’s most critical needs are addressed.

CDBG Water-Wastewater Construction

Oklahoma’s Community Development Block Grant-Water-Wastewater Construction program is for applicants that are ready to begin construction on a water or wastewater project. Eligible units of local government that provide documentation of final plans and specifications or a construction permit secured through the Oklahoma Department of Environmental Quality (ODEQ) may apply under this category. CDBG funds may only be utilized for construction, inspection, and administration costs. Engineering costs are prohibited.

Oklahoma Department of Commerce

Commerce is a trusted government agency that partners with businesses and communities for strategic and sustainable growth and success, moving Oklahoma forward to becoming a top ten state. As a result of SB 1447 (2024 Oklahoma Legislative Session), Commerce has recently restructured to focus on two key areas of focus: Community Outreach & Revitalization Enterprise (CORE) and Economic Development, Growth & Expansion (EDGE).

Our job is to bring jobs, investment, and economic prosperity to the state of Oklahoma. Through dynamic partnerships and innovative collaborations with companies, universities, not-for-profit organizations, and government leaders, we are building a business environment that supports business growth and shared community prosperity.

CDBG Community Revitalization

The primary National Objective of the Community Development Block Grant (CDBG) Program is the “development of viable urban communities by providing decent housing and a suitable living environment, particularly for persons of low and moderate incomes.” The CDBG National Objective “benefit to low and moderate-income-persons” is considered a funding PRIORITY under the State’s CDBG Program and is treated as such under the State’s individual CDBG set-asides. 

The Community Revitalization Program addresses quality of life needs in rural Oklahoma communities, helping these communities thrive, grow, and spark a sense of pride in citizens. An Applicant may submit a project proposal for any eligible activity listed under Section 105(a) of the Federal Housing and Community Development Act of 1974, as amended, other than water or wastewater projects.

Oklahoma Department of Commerce

Here at the Department of Commerce, our job is to bring employment, investment, and economic prosperity to the state of Oklahoma. Through dynamic partnerships and innovative collaborations with companies, universities, not-for-profit organizations, and government leaders, we are building a business environment that supports business growth and shared community prosperity.

Community Development Block Grant Programs

The Community Development Block Grant (CDBG) program enables rural Oklahoma communities to finance a variety of public infrastructure and economic improvements and helps promote job growth as a result of these improvements. CDBG funds are provided by the federal government (U.S. Department of Housing and Urban Development) and managed by the Oklahoma Department of Commerce to help ensure Oklahoma’s most critical needs are addressed.

CDBG Water + Wastewater Engineering

The Water and Wastewater Engineering Program funds water and wastewater projects that require more than one year to complete through a “phased approach”. Phase I of the Water and Wastewater Engineering program covers only engineering costs plus an appropriate amount of administration. Once the applicant receives their construction permit, the Community Development Division at Commerce will issue an award for construction, and the second phase (Phase II) of the project will begin.

The John H. Prescott Marine Mammal Rescue Assistance Grant supports the recovery and care of sick or injured marine mammals through federal assistance to the U.S. National Marine Mammal Stranding and Entanglement Response Networks. Eligible applicants must provide a Prescott Letter of Eligibility, confirming their participation in the network. This program aims to enhance marine mammal health monitoring and response capabilities across the country, ensuring timely and effective interventions for stranded marine life.

The BJA FY 2026 DNA Capacity Enhancement for Backlog Reduction (CEBR) Competitive Grants Program aims to enhance the capacity of state and local government crime laboratories for processing DNA samples. This program focuses on using DNA technology to improve forensic efficiency and implement Rapid DNA in booking stations. It targets jurisdictions with operational challenges, ensuring fair access to funding. Eligible agencies can apply for both competitive and formula CEBR funding.

The National Institute of Neurological Disorders and Stroke (NINDS) aims to enhance research on Amyotrophic Lateral Sclerosis (ALS) through intermediate patient population expanded access protocols. These protocols will provide investigational drugs to ALS patients while collecting vital data to inform future treatments and care strategies. This initiative seeks to better understand the disease's biomarkers, patient experiences, and the overall impact of investigational therapies, fostering advancements in ALS research and care.

Oklahoma Department of Commerce

Here at the Department of Commerce, our job is to bring employment, investment, and economic prosperity to the state of Oklahoma. Through dynamic partnerships and innovative collaborations with companies, universities, not-for-profit organizations, and government leaders, we are building a business environment that supports business growth and shared community prosperity.

Community Development Block Grant Programs

The Community Development Block Grant (CDBG) program enables rural Oklahoma communities to finance a variety of public infrastructure and economic improvements and helps promote job growth as a result of these improvements. CDBG funds are provided by the federal government (U.S. Department of Housing and Urban Development) and managed by the Oklahoma Department of Commerce to help ensure Oklahoma’s most critical needs are addressed.

CDBG Rural Economic Action Plan (REAP)

The CDBG REAP Program was developed in partnership with the Substate Planning Districts (SSPD) to make a greater impact on each district by matching CDBG funds dollar for dollar on each project in their respective area.

Oklahoma Department of Commerce

Here at the Department of Commerce, our job is to bring employment, investment, and economic prosperity to the state of Oklahoma. Through dynamic partnerships and innovative collaborations with companies, universities, not-for-profit organizations, and government leaders, we are building a business environment that supports business growth and shared community prosperity.

P3 Pooled Finance Program

Allows communities to utilize the state’s Pooled Finance Program for infrastructure development

This Public-Private Partnership (P3) program facilitates local infrastructure development where there is also a benefit to for-profit companies. Infrastructure development can include any critical infrastructure identified by local government entities contributing to the competitiveness of the region’s economy and essential for government functions.

P3 for Education and Workforce Development

Workforce development and access to skilled labor are critical factors for Oklahoma's companies to be competitive in the marketplace and for the continued success of the state's economic development efforts. Workforce boards, CareerTechs, colleges and universities have access to various tools that can help them obtain the necessary resources to develop a skilled workforce.

One of these tools is Oklahoma’s Public-Private Partnership for Education, a Public-Private Partnership (P3) program, that facilitates industry workforce development where there is also a benefit to for-profit companies and is intended to enhance an industry’s competitiveness, enhancing the region’s and state’s economy.

Projects must begin within 6 months of application approval. Awarded funds will not cover 100% of project costs.

What are eligible projects?

Projects where a CareerTech, college or university is providing industry-focused training that must be developed collaboratively with employers in a common industry.

How may the training be delivered?

Workforce training/instruction may be delivered solely by the applying entity or in conjunction with other eligible entities, which may include entities subject to State Department of Education (K-12). For example, a CareerTech may collaborate with a K-12 institution to provide industry-specific skills training.

How does it work?

• For-profit entities in a common industry that would benefit from specific skills development can collaborate with an applying entity to identify the skills required, method of delivery and tools needed to provide instruction.

• The qualifying educational institution would be allowed to capture state withholding taxes associated with those for-profit companies for a defined term to assist with the costs of developing a program and delivering the instruction.

Uses of funds can include the below:

• Assist with construction/renovation; or
• Purchase machinery/equipment; or
• Purchase training program; or
• Hire instructors (contract basis)

Oklahoma State Department of Education

The Oklahoma State Department of Education is the state education agency of the State of Oklahoma charged with determining the policies and directing the administration and supervision of the public school system of Oklahoma. The State Board of Education is composed of the Oklahoma State Superintendent of Public Instruction and six members appointed by the Governor of Oklahoma with the approval of the Oklahoma Senate. 

Together with the Oklahoma Department of Career and Technology Education and the Oklahoma State Regents for Higher Education, the Department forms the core of Oklahoma's public education system.

Oklahoma Comprehensive Literacy State Development Grant

The Oklahoma State Department of Education (OSDE) is pleased to announce the acquisition of a substantial grant totaling $58.9 million, with $11,228,650 allocated for the first year. This grant, awarded through the Comprehensive Literacy State Development Grant Program, will fund a transformative initiative in line with Oklahoma’s Comprehensive Literacy Plan. The initiative's primary objective is to enhance school readiness and improve language and literacy success among disadvantaged students throughout the state.

OCLSD Grant Overview

As part of this initiative, twenty districts across Oklahoma have been awarded subgranted funds to support the implementation of literacy programs specifically designed for their student populations, birth through grade 12. These subgrants will enable schools to improve literacy instruction, offer targeted interventions, and build a stronger foundation in language arts for their students.

The project aims to achieve the following key objectives:

• Early Language Development: Increase the percentage of participating four-year-old children making significant gains in oral language skills.
• Elementary Literacy Proficiency: Increase the percentage of participating fifth-grade students who meet or exceed proficiency levels on the Oklahoma State Testing Program (OSTP) English Language Arts (ELA) Assessment.
• Middle School Literacy Proficiency: Increase the percentage of participating eighth-grade students who meet or exceed proficiency levels on the OSTP ELA Assessment.
• High School Literacy Proficiency: Increase the percentage of participating eleventh-grade students who meet the college readiness benchmark in reading and English on the ACT.
• Teacher Training and Professional Development: Provide extensive training for Oklahoma teachers in the science of reading and effective literacy instructional strategies to ensure high-quality literacy education statewide.

The FY2026/2027 Community Compass Technical Assistance and Capacity Building Program provides competitive grants to organizations capable of delivering technical assistance (TA) to communities served by HUD. With up to $86 million available, recipients are expected to develop educational tools, collaborate with HUD, and show a strong record of performance. This initiative aims to enhance community systems, support high-priority projects, and ensure effective training delivery, fostering impactful outcomes across the nation.

The National Institute of Mental Health (NIMH) is launching a funding opportunity to establish a research network focused on rapid-acting psychotropic interventional drugs (RAPIDs), including ketamine and psilocybin. This initiative seeks to generate real-world evidence on the effectiveness and safety of these treatments for serious mental illnesses. By addressing critical questions around their implementation in clinical practice, the NIMH aims to facilitate the safe integration of RAPIDs into healthcare, ultimately improving mental health outcomes.

The National Endowment for the Humanities invites K-12 teachers and higher education faculty to apply for the Landmarks of American History and Culture and Summer Institutes program. This initiative aims to enhance humanities education through professional development opportunities, fostering a deeper understanding of historical and cultural landmarks. Participants will engage in enriching experiences designed to improve teaching practices and student learning outcomes in the humanities.

About

The Oklahoma Department of Environmental Quality web site’s goal is to provide all users with a functional, accessible and interactive web experience. We are continually striving to make all of our online resources as accessible as possible. In the meantime, if you encounter problems with any area of our site, please contact the site’s Webmaster. DEQ strives to ensure the accessibility of all electronic applications and publications to all individuals in compliance with applicable laws, including Oklahoma HB 2197 and Federal Section 508 accessibility laws.

Community Revitalization Program

The Site Cleanup Assistance Program (SCAP) has updated its Community Revitalization Program and introduced an application and ranking tools to select projects. Our goal continues to be working with City and County governments across the State to resolve environmental issues that are preventing property revitalization. This program allows for renewed use of a building or a site for business or government, and has the potential to revitalize communities by increasing the tax base, creating new jobs, and removing community eyesores and safety hazards. This program allows local communities to access the DEQ’s expertise in site cleanup, paving the way for reuse of a site or building.

While the focus of the Community Revitalization Program is asbestos and lead-based paint, properties that pose an imminent and substantial endangerment to human health and/or have other types of environmental contaminants may be considered on a case by case basis. If you believe your property poses an imminent and substantial threat, please contact the Community Revitalization program contact, Trenton Wilhelm.

KBF Ski Racing Safety

The KBF helps alpine ski clubs around the country purchase safety equipment like netting and padding, and also contributes to venue improvement initiatives. Funding requests are reviewed through an annual grant cycle with an application process. Over the past decade, the Kelly Brush Foundation has purchased thousands of rolls of b-netting, supported trail widening projects, and helped with the purchase of other safety equipment. 

KBF Ski Racing Safety Equipment Grants are all matching grants–meaning that any grant awarded by the Kelly Brush Foundation will need to be matched by the ski club. We expect that clubs will join us in making safety a priority by fundraising or finding room in their budget for safety.

The BJA FY 2026 Second Chance Act Community-based Reentry Program aims to support community organizations and tribal governments in providing essential mentoring and transitional services for individuals returning from correctional facilities. This initiative targets those assessed as moderate to high risk for recidivism, addressing their needs both pre-and post-release. By fostering successful reintegration into society, the program contributes to public safety and reduces recidivism rates, aligning with the mission of the U.S. Department of Justice.

The BJA FY 2026 Upholding the Rule of Law and Preventing Wrongful Convictions Program aims to enhance justice by strengthening the capacity of entities that review wrongful convictions. By supporting partnerships among criminal justice and victims' services, the program seeks to effectively manage post-conviction claims of innocence and prevent future errors. This initiative will help identify actual perpetrators and ensure justice for victims, contributing to public safety and the integrity of the legal system.