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Best Seed Grants for Nonprofits in Puerto Rico

Find the perfect Seed grants for nonprofits in Puerto Rico on Instrumentl. 9,000+ Seed grants for nonprofits in Puerto Rico in the United States.

9,000+

Available grants

$2.55B

Total funding

$5K

Median grant

9,000+ grants
$2.55B total
$5K median

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The Academy Martial Arts Leadership Scholarship

Community Foundation for the Fox Valley Region
Private
American Samoa, Guam +4 more
US $500

Our Mission

We strengthen our community for current and future generations by helping people make a difference in the lives of all.

We believe in our community’s lasting goodness. In fact, making sure our community is always a special place for us to live is why we’re here.

Scholarships

Through the generosity of our donors, we have more than $2 million in scholarships available in 2025 to students from more than 60 high schools. We offer scholarships to high school seniors, college and nontraditional students, and K-12 art and music camps and lessons.

The Academy Martial Arts Leadership Scholarship

Background

The Academy Martial Arts Leadership has been serving families in the Fox Cities since 1995. As the founders/owners, Jeff & Amanda Denu have been passionate about making our community stronger one Black Belt at a time teaching martial arts, while reinforcing respect, self-discipline, integrity, and excellence. Their passion with community involvement and creating a positive learning environment inspires others to be their personal best, and to make a difference every day.

Education - Higher Education

Optimizing Maternal RSV Immunization Delivery: A Systems-Based QI Initiative to Improve Uptake, Equity, and Newborn Outcomes Fund

Pfizer, Inc.
Corporate
United States
Up to US $200,000

Quality Improvement Grant Request for Proposals

Optimizing Maternal RSV Immunization Delivery: A Systems-Based Quality Improvement Initiative to Improve Uptake, Equity, and Newborn Outcomes

Pfizer, in collaboration with the Society for Maternal-Fetal Medicine (SMFM), is pleased to announce a competitive grant opportunity to support independent Quality Improvement (QI) initiatives focused on advancing maternal immunization, with a specific emphasis on Respiratory Syncytial Virus (RSV) vaccination during pregnancy.

This initiative builds upon insights generated from the Maternal Immunization Needs Assessment (MINA) project, a multi-stakeholder collaboration that identified persistent clinical, behavioral, and system-level gaps in the delivery and uptake of maternal vaccines.

We seek to fund projects that implement measurable, evidence-based interventions to improve real-world delivery of maternal RSV immunization across healthcare systems and care settings. Proposed initiatives should aim to optimize access, strengthen provider–patient communication training and tools, enhance care coordination, and address structural and behavioral barriers impacting vaccine uptake and equity.

Pfizer Global Medical Grants (GMG) supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies. Pfizer’s GMG competitive grant program involves a publicly posted Request for Proposal (RFP) that provides detail regarding a specific area of interest, sets timelines for review and approval, and uses an expert review panel (ERP) to make final grant decisions. Organizations are invited to submit an application addressing the specific gaps in clinical practice or care as outlined in the specific RFP.

For all QI grants, the applicant (and ultimately the grantee) will be solely responsible for the design, implementation, and conduct of the proposed initiative. Pfizer will have no involvement in project development, execution, or outcomes.

Obstetrics & Neonatal Care Maternal And Perinatal Health Vaccines & Immunizations +2 more

NIH Director's Transformative Research Award (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Director's Transformative Research Award encourages innovative research that challenges conventional ideas. This award supports bold scientists and teams aiming to create groundbreaking technologies and new clinical approaches, ultimately transforming scientific paradigms. As part of the NIH Common Fund's High-Risk, High-Reward Research Program, it seeks to fund high-impact projects that have the potential to significantly advance science and technology.
Science Health & Medicine Emerging Technology Development

Pathways to Enable Secure Open-Source Ecosystems

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $1,500,000
The Pathways to Enable Secure Open-Source Ecosystems (PESOSE) program, funded by the National Science Foundation, aims to transform open-source research into sustainable ecosystems that tackle national and societal challenges. This initiative promotes innovation across various sectors, including AI and cybersecurity, by fostering strong governance and broad user engagement. PESOSE invites proposals to establish and enhance open-source ecosystems, ensuring their safety, security, and effectiveness in meeting emergent needs.
Engineering Computer Science & Engineering Emerging Technology Development

NIH Director's Pioneer Award (DP1 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $700,000
The NIH Director's Pioneer Award (DP1) encourages innovative research by funding exceptional scientists. This award is designed for groundbreaking projects that diverge from the investigator's current work and address significant scientific challenges relevant to the NIH mission. Applications are invited across all NIH-relevant fields, promoting high-risk, high-reward research that could transform our understanding of critical scientific areas.
Science Health & Medicine Emerging Technology Development

Bear Paw Resort Scholarship

Community Foundation for the Fox Valley Region
Private
American Samoa, Guam +4 more
US $1,000
The Bear Paw Resort Scholarship, offered by the Community Foundation for the Fox Valley Region, supports graduating seniors from White Lake High School who plan to pursue post-secondary education. With over $2 million available for scholarships in 2025, this initiative aims to empower students in their educational journeys. The scholarship is designed to assist with tuition costs, payable after the completion of the first semester, thereby encouraging academic success and community development.
Education - Higher Education

Jean Dreyfus Lectureship for Undergraduate Institutions Grant

The Camille and Henry Dreyfus Foundation, Inc.
Private
American Samoa, District of Columbia +5 more
US $25,000
The Jean Dreyfus Lectureship for Undergraduate Institutions Grant provides a $25,000 award to facilitate a visit by a notable researcher in the chemical sciences to undergraduate institutions. It includes funding for summer research fellowships for two students and requires the researcher to deliver accessible lectures to the public. This initiative honors Jean Dreyfus's legacy and supports the engagement of undergraduates in scientific research and discourse.
Chemistry Chemical Engineering

Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement Clinical Trial Optional) (361408)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH is announcing a funding opportunity for competitive revisions of ongoing grants to tackle unforeseen public health crises. This Urgent Competitive Revision program aims to facilitate timely responses to emerging health challenges. Once the Notice of Funding Opportunity is published, eligible applications will be directly routed to the appropriate NIH awarding component. Only submissions in response to an Urgent Guide Notice published by an NIH Institute or Center will be accepted.
Epidemiology & Public Health

BMS Independent Medical Education Requests

Bristol Myers Squibb Foundation Inc
Private
United States
Unspecified amount
Bristol Myers Squibb Foundation Inc supports independent medical education to enhance healthcare professional competence and improve patient health outcomes. Their mission is to be a global leader in innovative medical education, focusing on evidence-based activities that address critical gaps in knowledge. By fostering excellence in healthcare, they aim to ensure measurable improvements in performance and patient outcomes across various disease areas.
Cancer / Oncology Cardiovascular Diseases & Systems Neurological Diseases & Disorders +7 more

AARP Community Challenge Grant: Flagship Grant

AARP Foundation
Association/Society
Puerto Rico, United States +1 more
Up to US $25,000
The AARP Community Challenge Grant supports projects that enhance community living for residents aged 50 and older. With a focus on immediate improvements and long-term progress, grants range from $10,000 to $25,000, covering areas like public spaces, transportation, and digital literacy. Since 2017, AARP has awarded over $20.1 million through more than 1,700 grants across the U.S. Eligible organizations include nonprofits and government entities committed to serving the needs of older adults.
Senior Services

EDA Philadelphia FY 2016–FY 2019 Planning Program and Local Technical Assistance Program

US Department of Commerce: Economic Development Administration (EDA)
Federal Government
Connecticut, Delaware +14 more
US $40,000 - US $300,000
The EDA Philadelphia FY 2016–FY 2019 Planning Program and Local Technical Assistance Program aims to enhance regional economic development by providing grants for creating and implementing Comprehensive Economic Development Strategies (CEDS). This initiative supports eligible organizations, including Indian Tribes and District Organizations, to develop plans that foster economic prosperity and job retention in distressed areas. Through various investments, the program strengthens local capacities for effective economic development and job creation.
Economic Services & Development

Paul B. Beeson Emerging Leaders Career Development Award in Aging (K76 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Paul B. Beeson Emerging Leaders Career Development Award in Aging is designed for early-stage physicians and health professionals committed to aging research. This initiative, supported by the NIH, aims to cultivate leadership skills and advance research in geriatrics. Eligible candidates must demonstrate prior research support and leadership in their field. While applications are not currently being accepted, this NOFO encourages potential applicants to develop collaborative and impactful projects in aging research.
Aging / Gerontology

Mutual Self-Help Housing Technical Assistance Grants in Puerto Rico

USDA: Rural Development (RD)
Federal Government
Puerto Rico
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in Puerto Rico provide essential support to organizations aiding low-income families in constructing their own homes. These grants enable recipients to offer technical guidance and supervision, facilitating community-driven housing projects. Eligible entities include government non-profits and federally recognized tribes, while funding cannot be used for direct construction labor or purchasing materials. This program fosters self-sufficiency and strengthens community ties in rural areas.
Real Estate & Housing

Bonnycastle Fellowship for Wetland and Waterfowl Research

Ducks Unlimited
Private
North America
Up to C $17,000
The Bonnycastle Fellowship for Wetland and Waterfowl Research supports graduate students in advancing conservation efforts. Offered by Ducks Unlimited, this fellowship provides up to $17,000 annually for research and personal support. The fellowship emphasizes the importance of research originality, ecological contributions, and feasibility. It is open to all North American graduate students, with a preference for doctoral candidates. The award is renewable for PhD students up to two years, and once for Master's students, contingent on satisfactory progress.
Ornithology Limnology Ornithological Conservation +2 more

Recordings at Risk Grant

Council on Library and Information Resources (CLIR)
Private
American Samoa, Guam +4 more
US $10,000 - US $50,000
The Recordings at Risk Grant, administered by CLIR, supports the preservation of rare audio and audiovisual media of scholarly value through digital reformatting. With funding from The Andrew W. Mellon Foundation, the program aims to award $6.75 million across twelve competitions, offering grants between $10,000 and $50,000. It encourages U.S. nonprofit institutions to preserve vulnerable media, helping them to develop strategies for effective digital reformatting and promoting best preservation practices.
Historical Records & Archives

AAPD Foundation: Access to Care Grants

Foundation of the American Academy of Pediatric Dentistry
Private
American Samoa, Guam +5 more
Up to US $30,000
The AAPD Foundation provides Access to Care Grants aimed at ensuring dental care is accessible for all children. As the largest dentist-led charity, it supports community programs that deliver essential dental services. With a focus on innovative ideas and effective grant utilization, the foundation works tirelessly to promote healthy smiles for every child. By partnering with pediatric dentists, it strives to make a meaningful impact in communities nationwide.
Dental Health

DoW Orthopaedic, Clinical Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
US $2,000,000 - US $3,200,000
The FY26 Orthopaedic Research Program Clinical Research Award supports vital clinical research addressing orthopaedic-specific factors and interventions. It aims to generate evidence that optimizes patient outcomes and informs clinical care, benefiting Service Members, Veterans, and the public. Applications should focus on priority areas such as Ligamentous Trauma and Military Women’s Health, ensuring significant impact on patient care and mitigation of orthopaedic injuries.
Orthopedics

DoW Orthopaedic, Applied Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $950,000
The DoW Orthopaedic Applied Research Award supports innovative research aimed at improving treatment and functionality for individuals with combat-related orthopaedic injuries. Applicants are required to present preliminary data and focus on applied research that evaluates new solutions, including pharmacologic agents and rehabilitation techniques. This initiative emphasizes the importance of military relevance, aiming to benefit Service Members, their families, and Veterans, while clinical research proposals are not permitted.
Orthopedics

RPAC Fundraising Grants

National Association Of Realtors
Private
American Samoa, Guam +4 more
US $5,000 - US $45,000
The RPAC Fundraising Grants, offered by the National Association of Realtors, support state and local associations in organizing fundraising events aimed at boosting RPAC contributions. These grants require a fundraising goal three times the amount requested, ensuring tangible results. The initiative emphasizes developing detailed fundraising plans that comply with state laws regarding corporate treasury funds. This program is vital for enhancing RPAC participation and advancing property ownership advocacy.
Real Estate & Housing Nonprofit Growth & Development

Limited Competition: Biomedical Research Environment & Sponsored Programs Administration Development (BRE-SPAD) Program

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Limited Competition: Biomedical Research Environment & Sponsored Programs Administration Development (BRE-SPAD) Program aims to enhance the research capacity of resource-limited institutions. By focusing on essential areas like biomedical research environment and sponsored programs administration, this initiative seeks to foster rigorous and reproducible biomedical research. Eligible organizations are encouraged to submit proposals addressing their specific needs, thereby expanding the pool of qualified researchers and strengthening the settings for NIH-funded research.
Biology Health & Medicine

Kids’ Chance of America: Emergency Grant Program

Kids’ Chance of America
Association/Society
American Samoa, Guam +4 more
Unspecified amount
The Kids’ Chance of America: Emergency Grant Program aims to provide essential support to state organizations facing unexpected challenges in funding scholarships for children of injured workers. This initiative ensures that these children can continue their education despite unforeseen financial hardships. Grants can be utilized for scholarships, room, board, and educational fees, emphasizing the importance of maintaining educational support for deserving students during the 2023-2024 academic year.
Academic Scholarship Programs Nonprofit Growth & Development

TYLENOL Future Care Scholarship

Tylenol
Corporate
District of Columbia, Puerto Rico +1 more
US $5,000 - US $10,000
The TYLENOL Future Care Scholarship supports students pursuing healthcare careers, continuing a 30-year tradition of helping those dedicated to caring for others. Eligible applicants must be U.S. residents, graduate students or seniors enrolling in graduate school for the 2024-25 academic year, and provide proof of enrollment in an accredited healthcare program. Scholarships cover tuition, fees, and necessary supplies, ensuring that future healthcare professionals receive the support they need.
Medical Education & Professional Training

F26AS00104 State ANS Management Plan 2026

US Department of the Interior: Fish and Wildlife Service (FWS)
Federal Government
United States
US $5,000 - US $150,000
The F26AS00104 State ANS Management Plan 2026 aims to combat aquatic nuisance species through pre-proposals followed by full applications. Managed by the US Department of the Interior's Fish and Wildlife Service, this initiative requires a 25% cost-share and limits administrative costs to 5%. Applications are due by October 14, 2026, though the funding opportunity closes on December 16, 2026. The plan is crucial for maintaining biodiversity and supporting a coordinated national approach to invasive species management.
Ichthyology (Fish) Limnology Fisheries +1 more

Ashland County Wildlife Conservation League David McClure Memorial Scholarship

Ashland County Community Foundation
Private
United States
Unspecified amount
The Ashland County Wildlife Conservation League David McClure Memorial Scholarship supports graduating seniors from Ashland County high schools and alternative education programs pursuing a degree in wildlife-related fields. Applicants must maintain a GPA of 3.0 or higher and be accepted into accredited colleges or vocational programs. This scholarship fosters educational growth while promoting conservation efforts, reflecting the commitment of the Ashland County Community Foundation to enhance community development and support future leaders in wildlife conservation.
Education - Higher Education Career / College Preparation Education - High School +5 more

IDeA Networks of Biomedical Research Excellence (INBRE)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
Alaska, Arkansas +22 more
Unspecified amount
The IDeA Networks of Biomedical Research Excellence (INBRE) program aims to enhance biomedical research capacity in underfunded states by fostering collaborations among research institutions. By supporting faculty research, mentoring, and student involvement, INBREs create pathways for undergraduate students to enter biomedical careers. This initiative not only promotes institutional partnerships but also strengthens research infrastructure, ultimately contributing to a more robust scientific community in IDeA states.
Biology Health & Medicine

Microplastics Research and Resource Coordination Center (U24 - Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Microplastics Research and Resource Coordination Center aims to foster collaboration among researchers in biomedical and material sciences to understand the health impacts of micro/nanoplastics (M/NPs). This initiative will enhance research reliability by standardizing sampling, analytical practices, and data harmonization. The center will lead efforts in best practices and provide essential guidance to the M/NPs research community, ultimately advancing knowledge and methodologies in this critical area of study.
Materials Science and Engineering Nanomaterials & Nanotechnology

NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Collaborative International Research Project aims to foster international research collaborations that align with the NIH mission. This grant encourages applications that incorporate at least one international subproject, offering oversight and tracking for NIH-funded international initiatives. Projects should leverage unique resources or populations abroad, contributing to advancements in health sciences relevant to NIH's objectives. This initiative underscores the importance of global partnerships in enhancing research capabilities and outcomes in the United States.
International / Foreign Affairs

Seed Grants for Nonprofits in Puerto Rico Highlights

Looking for seed grants for nonprofits in Puerto Rico?


Read more about each grant below or start your 14-day free trial to see all seed grants for nonprofits in Puerto Rico recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Seed Grants for Nonprofits in Puerto Rico

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

800+ Seed grants for nonprofits in Puerto Rico grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

500+ Seed grants for nonprofits in Puerto Rico over $25K in average grant size

400+ Seed grants for nonprofits in Puerto Rico over $50K in average grant size

16 Seed grants for nonprofits in Puerto Rico supporting general operating expenses

500+ Seed grants for nonprofits in Puerto Rico supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Seed grants for Nonprofits in Puerto Rico?

Most grants are due in the first quarter.

Q1
31.5%
Q2
23.7%
Q3
19.8%
Q4
25.0%

Typical Funding Amounts

What's the typical grant amount funded for Seed Grants for Nonprofits in Puerto Rico?

Grants are most commonly $318,750.

$375 $375 Min.
$318,750 $318.8 K Median
$1,385,019 $1.4 M Average
$80,000,000 $80 M Max.

Average Grant Size

What's the typical amount funded for Puerto Rico?

Grants are most commonly $104,638.

$104,638

Total Number of Grants

What's the total number of grants in Seed Grants for Nonprofits in Puerto Rico year over year?

In 2024, funders in Puerto Rico awarded a total of 1,758 grants.

2022 1,942

2023 1,805

2024 1,758

Top Grant Focus Areas

Among all the Seed Grants for Nonprofits in Puerto Rico given out in Puerto Rico, the most popular focus areas that receive funding are Education, Human Services, and Human Service Organizations.

1. Education

2. Human Services

3. Human Service Organizations

Funding Over Time

How is funding for Seed Grants for Nonprofits in Puerto Rico changing over time?

Funding has increased by 15.38%.

2022 $135,836,997

2023 $159,254,276
17.24%

2024 $183,744,801
15.38%

Puerto Rico Counties That Receive the Most Funding

How does grant funding vary by county?

San Juan County, Dorado County, and Loiza County receive the most funding.

County Total Grant Funding in 2024
San Juan County $85,833,046
Dorado County $27,296,199
Loiza County $11,736,039
Bayamon County $11,338,985
Vega Alta County $9,404,211