Best Health and Wellness Grants for Nonprofits in North Carolina

The Creag Foundation, established in 2009 in Woodinville, Washington, provides funding to innovative 501(c)(3) nonprofit organizations addressing social issues. Focused on smaller organizations, the foundation seeks to support those with unique approaches to improve the human condition. Eligible applicants must have held 501(c)(3) status for at least one year and present a new or previously unaddressed solution to societal challenges. Applications are by invitation only, encouraging creativity and passion in charitable work.

The DanPaul Foundation aims to enhance early childhood development by training teachers and parents, protecting children from abuse, and promoting social responsibility. They provide grants to non-profits for programs that focus on education, health, and welfare of youth. Key initiatives include scholarships, environmental education, and support for underprivileged children. Grant amounts range from a few hundred dollars to $15,000 annually, with a focus on impactful, community-driven projects.

The Obici Healthcare Foundation offers Community Engagement Grants to support nonprofit initiatives that enhance the health of local residents. These one-time grants, ranging from $500 to $5000, are intended for programs that address community health needs, promote wellness, and improve health awareness. Applications are accepted on a rolling basis, and the Foundation prioritizes collaborative projects that innovate and sustain long-term health improvements in Virginia and North Carolina.

The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.

The Healthy Futures Grants, offered by The Health Foundation, support nonprofits and governmental entities in Wilkes County, North Carolina. These grants fund building projects, equipment purchases, program support, expansion of services, and training. To apply, interested parties must first complete a Letter of Interest to gain access to the full application. Grants are accepted on a rolling basis, ensuring ongoing opportunities for community health improvement.

The Dudley T. Dougherty Foundation Grant supports nonprofit charitable organizations recognized under section 501(c)(3) of the IRS Revenue Code. Established in 2002, the foundation aims to empower groups committed to positive change, fostering respect for life and the environment. Their vision emphasizes collaboration for a better future, encouraging applicants to embody these values in their initiatives. With a focus on impactful projects, this grant is an opportunity for organizations striving to make a critical difference in our world.

The Georgia-Pacific Foundation Grant supports organizations in the Metro Atlanta area, focusing on education, entrepreneurship, community enrichment, and environmental sustainability. Established in 1958, the foundation prioritizes investments that align with its mission and values, promoting long-term well-being within communities where Georgia-Pacific operates. Eligible applicants include 501(c)(3) nonprofits, public schools, and local government entities located within 30 miles of GP manufacturing sites.

The Philip L. Van Every Foundation provides grants to 501(c)(3) organizations in North and South Carolina, focusing on education, healthcare, human services, and the arts. With a commitment to strengthen communities and support fiscal responsibility, the foundation aims to enhance lives through meaningful projects. Organizations must demonstrate a track record of success to be eligible for funding, which is generally awarded for special projects and capital needs.

The Spark Good: Strengthening Community Local Grants program by the Wal-Mart Foundation empowers local organizations through grants ranging from $250 to $5000. This initiative aims to enhance community welfare by supporting diverse projects, including animal shelters and educational programs. Eligible organizations must have a verified Spark Good account, ensuring funds are allocated effectively to meet local needs and foster community development. Together, we can create lasting impacts through small yet significant actions.

The Dr. Scholl Foundation offers grants annually to IRS 501(c)(3) organizations, primarily focusing on U.S. applicants. The foundation supports projects in education, social services, healthcare, civic and cultural initiatives, and environmental efforts. While the grant cycle runs from October 1 to March 1, it encourages innovative solutions to global challenges. Only one application per organization is accepted each year, and funding is limited to one year. Unqualified organizations, including political entities, are ineligible.

The Mary Duke Biddle Foundation's Arts Grant Program provides multiyear funding to arts nonprofits and PreK-12 education organizations in North Carolina's Triangle region. With grants ranging from $20,000 to $50,000 annually, the program focuses on supporting developing and established organizations, emphasizing artistic excellence and community engagement. Eligibility includes a commitment to diversity, equity, and inclusion. This initiative aims to strengthen the cultural sector, foster growth, and enhance the overall well-being of communities through arts programming.

Purpose

The purpose of the Early Childhood Education and Development Fund is to ensure that every child in Buncombe County has an equal opportunity to thrive during their first 2,000 days, including access to quality early childhood education. The Fund was established in response to a well-documented local shortage of quality early childhood education programs, barriers that families face in accessing existing programs, including affordability, and a well-documented shortage of qualified teachers and staff in classrooms and centers.

Funding

Grants may be awarded up to the total amount of $4,054,185, the anticipated budget for the Early Childhood Education and Development Fund for FY2027 (subject to budget adoption). On October 30, 2018, the Board of Commissioners for Buncombe County voted to create the Early Childhood Education and Development fund for the purpose of annually investing $3.6 million beginning in the FY2020 budget with an annual increase of 2% in future years. 

Funding is earmarked to support early care and education for children birth through kindergarten. This includes the following categories:

• infants/toddlers – ages six (6) weeks to three (3) years old
• preschoolers – ages three (3) to five (5) years old
• pre-kindergarteners (pre-k) – 4 year old rising kindergarteners (4 years old by August 31st)

The Camber Foundation Grant supports community-driven initiatives in Eastern North Carolina, focusing on health, education, and economic development. It encourages nonprofits to apply for funding to enhance services without discrimination. Priorities include access to healthcare, mental health programs, and youth development. Eligible organizations must be 501(c)(3) entities based in the region, ensuring that all residents can thrive. The foundation aims to uplift communities through collaborative efforts and innovative solutions.

The Women for Women of Pitt County initiative, supported by the North Carolina Community Foundation, aims to empower women and girls in Pitt County through various programs. Grants ranging from $5,000 to $15,000 will fund projects that promote economic self-sufficiency, prevent violence, and enhance community participation. With a total grant pool of $103,000, this initiative seeks to create lasting positive impacts on the lives of women and girls, fostering their growth and well-being.

The North Carolina Appalachian Regional Commission Funds support economic development across 13 states, focusing on infrastructure, workforce, and community resilience. Administered by the North Carolina Department of Commerce, the program prioritizes projects that enhance local economies, particularly in areas affected by Hurricane Helene. Funding caps are set at $700,000 for construction and $300,000 for non-construction projects, with special considerations for distressed counties and workforce development initiatives.

The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.

The AmeriHealth Caritas Foundation Grant aims to prevent and mitigate adverse childhood experiences (ACEs) to promote healthier outcomes for children. With a focus on empowering families, healing behaviors, and access to healthcare, the foundation supports nonprofit organizations that provide comprehensive care and resources. Grants range from $100,000 to $250,000, totaling up to $1.945 million for project-specific initiatives. Eligible organizations must be 501(c)(3) nonprofits operating in states where AmeriHealth Caritas Medicaid markets exist.

Enterprise Community Partners

Enterprise Community Partners is a national nonprofit that exists to make a good home possible for the millions of families without one. Home is where life happens, where plans are made, and futures begin. It is the foundation for dignity, health, education, wealth, and community. Yet rents keep going up, paychecks don’t keep pace, and good homes in strong neighborhoods are increasingly out of reach.

The system doesn’t work. It must be changed, and it must be changed by us.

Enterprise has the breadth, scale, and expertise to do it. We support community development organizations on the ground. We aggregate and invest billions to improve housing and strengthen communities across the U.S. We advance housing policy at every level of government. We build and manage communities ourselves. Everything we do is informed by the residents we serve.

Together with our partners, we focus on the greatest need — the massive shortage of affordable rental homes — to achieve three goals:

• Increase the supply of affordable homes
• Advance racial equity after decades of systematic racism in housing
• Support residents and strengthen communities to be resilient to the unpredictable, and make upward mobility possible

Since 1982, we have invested $92.0 billion and created 1.1 million homes across all 50 states, the District of Columbia, Puerto Rico, and the U.S. Virgin Islands. We do all this to make home and community places of pride, power, and belonging.

National Housing Innovation Grant Competition

Home is foundational. It’s where we plant roots, raise and care for our families, and build community bonds. Yet in every corner of the country, millions of people of all ages and backgrounds need a home they can afford.

Wells Fargo is meeting this moment with a powerful grant opportunity. Together with Enterprise, Wells Fargo has launched the third iteration of the Housing Affordability Breakthrough Challenge. The 2026 cycle of the housing innovation competition will identify and propel proven, ready-to-scale solutions that transform current practices and increase housing choice and access.

Eligible applicants will compete for five individual grants of $2 million to advance their innovation and drive meaningful, systems-level change in the housing and adjacent industries. Winners will gain access to mentorship and coaching from industry leaders and experts and join a powerful network of Breakthrough Challenge innovators.

Focus Areas

This third cycle of the Housing Affordability Breakthrough Challenge aims to meet the nation’s affordable housing challenges across all types of communities: Native, rural, suburban, tribal, and urban.

Proposals must encompass one or more of three focus areas:

• Design and Construction
• Finance
• Service Delivery and Programs

Applicants will be asked to show how their proof of concept or pilot program has achieved clear outcomes and success, and provide a clear pathway to expanding the innovation’s reach and impact

Round 1: Criteria and Scoring

Your innovation must meet the criteria below to advance to the official scoring stage.

Type of Community

Innovations can serve all types of communities:

• Rural
• Urban
• Suburban
• Tribal

Location

Priority scoring will be given to applications from entities that are based in – or whose innovations are designed for – one or more of these 28 states, plus D.C.:

• Alaska, Arizona, Arkansas, California, Colorado, Florida, Georgia, Idaho, Illinois, Iowa, Maryland, Massachusetts, Minnesota, Montana, Nevada, New Jersey, New Mexico, New York, North Carolina, North Dakota, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, Utah, Virginia, Washington, Washington D.C.

Affordability

Innovations must serve residents at these income levels:

• Rental: 80% AMI or below
• Homeownership: 120% AMI or below
• Workforce housing: 120% AMI or below

The Dogwood Health Trust: Collaboration & Innovation Grant aims to support innovative collaborations addressing the challenges faced by Western North Carolina communities post-Hurricane Helene. With grant sizes ranging from $50,000 to $500,000, this initiative focuses on fostering community-wide networks that enhance housing, education, and health. It prioritizes resources for underserved communities, encourages creative solutions, and strengthens coalitions to improve systemic responses to local needs, ensuring impactful and sustainable outcomes.

The Dogwood Health Trust provides an Organizational Capacity Building Grant aimed at enhancing the operational strength and sustainability of nonprofit organizations in Western North Carolina. Grants range from $15,000 to $50,000 and support initiatives that align with health, education, housing, and economic opportunities. This funding is crucial for nonprofits that do not directly support program expenses, ensuring that local organizations can thrive and contribute to community wellbeing.

The Youth and Young Adult Well-Being Grant from the Nantahala Health Foundation aims to enhance the health and well-being of youth and young adults aged 5 to 24 in Western North Carolina. This initiative encourages partnerships with local organizations to address critical issues, such as mental health and educational support. Grant awards can be up to $100,000, focusing on innovative projects that foster resilience and improve health outcomes for underserved populations.

The Universal Leaf Foundation Grants support 501(c)(3) nonprofit organizations primarily in areas where Universal Leaf Tobacco Company operates. Focus areas include education for at-risk individuals, higher education, civic/community arts, and environmental initiatives. The Foundation emphasizes good corporate citizenship and community engagement through financial support and employee volunteerism. Organizations must operate within designated geographic areas and cannot be involved in political advocacy or restrict services based on demographics. Grants aim to enhance community well-being and educational opportunities.

The GSK IMPACT Awards in North Carolina honor outstanding nonprofit organizations making a significant impact on community health. This annual program, in partnership with the Triangle Community Foundation, recognizes up to ten organizations for their exemplary contributions to health and wellness. Applicants must demonstrate a commitment to improving community health through innovative and effective programs. Eligible organizations must operate in the Triangle area and meet specific criteria regarding revenue and community impact.

The John William Pope Foundation provides annual grants focusing on human services and the arts, primarily in North Carolina's Wake and Vance Counties. Established in 1986, the Foundation promotes self-reliance and community responsibility, funding initiatives that address critical social challenges. By prioritizing private resources over government funding, it fosters creative expression and supports nonprofits that empower individuals and families. The Foundation's mission is to ensure future generations have equal opportunities for success.

The Louise Oriole Burevitch Endowment Grant, offered by the North Carolina Community Foundation, supports nonprofit organizations focused on education, health, and human services in eastern North Carolina. This competitive grant aims to enhance community well-being by funding programs that address basic human needs, promote health outcomes, and support educational initiatives. Eligible applicants include 501(c)(3) organizations, with preferences for projects benefiting women, children, and the elderly in the southeastern region.

The Arts Grant Program, funded by the Mary Duke Biddle Foundation, aims to support arts nonprofits and educational organizations in North Carolina's Triangle region. This program offers one-year grants ranging from $5,000 to $10,000 to eligible organizations that have not received funding in the past five years. The initiative emphasizes the importance of arts in community building, cultural preservation, and personal enrichment, fostering a vibrant and inclusive cultural landscape.