Best Sioux Falls Grants for Nonprofits in South Dakota

The Critical Needs List by Community Foundation Tampa Bay addresses urgent, unforeseen needs of nonprofits that threaten their ability to serve the community. This innovative program allows nonprofits to submit requests for funding up to $250,000 for critical expenses such as emergency repairs and essential equipment replacement. With a focus on supporting local organizations, the program aims to match funding with community philanthropists, ensuring timely assistance to those in need.

The Economics program by the National Science Foundation supports research to enhance understanding of the U.S. economy and global systems. It prioritizes interdisciplinary studies and encourages diverse proposals, including those from junior faculty and underrepresented groups. Funding opportunities range from individual projects to doctoral dissertation improvement grants, emphasizing rigorous economic analysis and data collection. The program aims to strengthen links between economics and other disciplines, fostering innovative research in various economic subfields.

The SCI Research on the Translational Spectrum (SCIRTS) portfolio aims to promote innovative research that enhances function and alleviates complications following spinal cord injuries. It encourages studies that involve individuals with SCI, emphasizing translational significance in research designs. SCIRTS grants support diverse research areas, including mechanistic, preclinical, and clinical studies, to develop effective interventions. Funding categories include Postdoctoral Fellowships, Pilot Research Grants, and Senior Research Grants, targeting early-career and senior investigators to advance spinal cord injury research.

The Yass Prize & STOP Awards Initiative aims to revolutionize education by recognizing and supporting exceptional education providers focused on Sustainable, Transformational, Outstanding, and Permissionless (STOP) education. Established in 2021, the initiative awards funds to organizations serving Pre-K to 12th grade students across the United States, fostering impactful partnerships and innovative practices. With a commitment to transforming educational experiences, the initiative celebrates the vital work of educators in response to contemporary challenges.

Request for Proposals

Community Care Corps encourages organizations across the country to apply for 18-month grants ($30,000–$200,000) to develop and scale innovative volunteer programs that provide nonmedical assistance to older adults, adults age 18 and older with disabilities and family caregivers.

Projects funded through this initiative will increase the number of community-based volunteer programs available to provide nonmedical assistance while decreasing the number of older adults, adults with disabilities, and family caregivers who need assistance in maintaining independence in the community but are unable to obtain help. In doing so, the initiative will strengthen community-based supports that help people maintain independence, reduce unmet needs, and improve overall well-being.

The Human Networks and Data Science (HNDS) program, supported by the National Science Foundation (NSF), focuses on enhancing our understanding of human behavior through data and network science. It features two tracks: HNDS-I, aimed at developing data resources for social sciences, and HNDS-R, which leverages large datasets to advance theoretical frameworks in core social, behavioral, and economic disciplines. Proposals are encouraged to provide innovative insights that can lead to significant societal benefits.

The Energy, Power, Control, and Networks (EPCN) Program, managed by the National Science Foundation, fosters innovative research in multi-agent systems, resource allocation, and machine learning. It focuses on applications in energy, transportation, and robotics, while emphasizing the integration of renewable energy into power systems. EPCN also explores advanced power electronics, cybersecurity for grids, and the development of adaptive systems. This program encourages groundbreaking advancements in energy-efficient technologies and promotes collaboration in addressing complex challenges.

The Diversity and Inclusiveness Grant Program by the American Philosophical Association aims to enhance the participation of underrepresented groups in philosophy. With funding up to $20,000, the program seeks innovative projects that impact diversity across various demographics including women, racial minorities, and LGBTQ+ individuals. Proposals are evaluated on their philosophical quality, feasibility, and potential broader impact, particularly within the US and Canada, making this an essential opportunity for promoting inclusivity in philosophical discourse.

The Centers of Research Excellence in Science and Technology (CREST) program, funded by the National Science Foundation, aims to strengthen research capabilities at Minority-serving institutions (MSIs). It encourages the integration of STEM research and education, promoting diversity within the workforce. Successful proposals are expected to demonstrate innovative strategies for broadening participation and achieving national competitiveness in research. CREST Centers will also foster partnerships that advance significant research themes, ensuring sustained support and development for underrepresented groups in STEM.

The ASPCA Research Grants support innovative research aimed at enhancing animal welfare. With a total funding amount of $440,000, the grants are open to various research areas including cruelty research, access to veterinary care, applied behavior, psychological trauma, and farm animal welfare. Eligible applicants include U.S. public or private entities and Canadian universities. The maximum individual grant amounts vary by research area, encouraging impactful studies that directly benefit animals.

The Chapman Prize, established by the Daniel and Barbara Chapman Trust, honors individuals and organizations making significant contributions to American society. Each year, the award focuses on a theme; in 2025, it will spotlight Economic Prosperity. Eligible applicants include U.S. citizens and nonprofits with three years of charitable work demonstrating impact in the chosen field. Approximately $100,000 will be awarded annually to support endeavors that enhance economic prosperity through various initiatives.

The FY 2025 EDA Public Works and Economic Adjustment Assistance Programs aim to enhance economic growth and resilience in distressed communities. EDA invites ongoing applications for funding, focusing on innovative approaches that leverage regional strengths. The updated NOFO emphasizes timely reviews and outlines submission procedures for core programs under the Public Works and Economic Development Act. Grantees are encouraged to develop unique initiatives that foster lasting economic prosperity.

The Citi Foundation's Global Innovation Challenge invites proposals from community organizations worldwide developing innovative employment solutions for low-income youth aged 15 to 24. This initiative aims to enhance youth employability, addressing global unemployment challenges faced by millions. Eligible organizations can apply for funding to support programs such as vocational training, entrepreneurship, and financial education to empower young people. The deadline for application registration is March 4, 2025, at 12 p.m. Eastern Time.

The Richard King Mellon Foundation invites innovative proposals that align with their 2021-2030 Strategic Plan, aiming to invest over $1.2 billion to enhance opportunities in southwestern Pennsylvania. Their funding focuses on conservation, economic development, economic mobility, health and well-being, organizational effectiveness, and social-impact investments. The General Application offers flexibility without deadlines, allowing for a variety of support types, including project-specific and general operating funding, aimed at enriching community vitality and environmental stewardship.

The Region 4 Professional Development Awards for 2025-2026 foster the growth of health information access and data science skills among network members. This funding supports diverse projects such as workshops, conferences, and educational activities aimed at enhancing the professional capacity of individuals affiliated with NNLM Region 4. By encouraging proposals that address the needs of underrepresented communities, the awards aim to improve health information services and access across the region.

The IAF Research Fellowship Program, administered by the Social Science Research Council, aims to support rigorous research on community-led development in Latin America and the Caribbean. The fellowship provides a $20,000 stipend for twelve months, fostering innovative solutions to pressing issues such as economic opportunity, migration, and social inclusion. Researchers are encouraged to explore how community-led models can create lasting impacts and respond to global trends, enhancing local resilience and development.

The Abbey Mural Prize, established in 1932, supports the creation and restoration of public murals across the United States. This prestigious award, administered by the National Academy of Design since 1940, emphasizes projects that enhance community engagement and social activism through art. Grants typically range from $10,000 to $40,000, with a total annual funding cap of $125,000. Eligible applicants include artists, architects, and nonprofit organizations committed to impactful mural projects.

The UEF Grant Program, offered by the United Engineering Foundation, supports innovative projects that enhance the engineering profession and public welfare. With an annual budget of nearly $800,000, the program awards 5 to 10 grants each year. Eligible applicants must be U.S.-based organizations with 501(c)(3) status. Preference is given to interdisciplinary proposals that engage the community and integrate various engineering fields, fostering collaboration and addressing important societal issues.

The Smart Growth Grants program, managed by the National Association of Realtors, aims to enhance community development through educational initiatives aligned with Smart Growth Principles. Available in three levels, the grants support REALTOR Associations in promoting sustainable land use, community planning, and stakeholder engagement. Maximum awards range from $3,000 to $15,000, depending on the grant level. Note that the program is currently not accepting applications for 2025 and will reopen in January 2026.

The PATH Scholarship, established by the Ellucian Foundation in 2020, aims to support higher education institutions in assisting students facing financial hardships. With over $2.9 million awarded, it has benefited more than 3,100 students. Eligible institutions can receive grants ranging from $10,000 to $25,000, with individual awards up to $1,500. This initiative encourages public two-year colleges, particularly Minority Serving Institutions, to apply and adapt award criteria to meet the needs of their students.

The SD Conservation Stewardship Program (CSP) is a federal initiative designed to enhance conservation efforts on private agricultural lands. By providing technical and financial assistance, CSP helps producers improve soil health, water quality, and wildlife habitat while maintaining agricultural productivity. Participants can receive annual payments for implementing conservation practices, ensuring long-term sustainability. With a focus on tailored conservation plans, CSP addresses various resource concerns, promoting resilience against climate impacts and market fluctuations.

The BRAIN Initiative Advanced Postdoctoral Career Transition Award (K99/R00) aims to enhance diversity in neuroscience by supporting talented postdoctoral researchers from various backgrounds. This program facilitates their transition to independent faculty positions, providing essential NIH research support to help launch competitive research careers. Applications are due in February, June, and October for standard grants, and in March, July, and November for renewals.

The Lots of Compassion Grant, supported by KidsGardening and Mrs. Meyer’s Clean Day, aims to transform vacant urban lots into thriving community gardens. By providing $20,000 to each of the 10 selected grantees, the initiative focuses on empowering under-resourced communities, fostering social connections, and enhancing mental health. The grant prioritizes organizations that involve diverse participants and demonstrate significant community impact, ensuring that the gardens not only flourish but also cultivate kindness and compassion.

This funding opportunity invites Small Business Technology Transfer (STTR) grant applications aimed at developing FDA-regulated medical products for patients with opioid and stimulant use disorders. Projects may focus on pharmacotherapeutics or diagnostic devices, including software. The initiative seeks to address the ongoing opioid crisis by supporting innovations that enhance treatment options for individuals and communities affected by these disorders.

The B.W. Bastian Foundation Grant supports organizations committed to equality for all Americans, including the LGBTQ+ community. Grants typically range from $100 to $15,000, and applicants must have 501(C)3 tax status. Funding is primarily for projects in the Intermountain West and may include general operating support or specific programs. Organizations should first inquire before applying, especially if requesting more than previous grants. The foundation does not fund individuals or lobbying efforts.

The AISES SPRK-ing Interest in Computer Science program engages Indigenous K-12 students through fun coding and robotics activities. By utilizing Sphero BOLT and Indi robots, students gain hands-on experience in STEM and computer science, fostering greater interest and competency in these fields. Participating schools receive essential materials and training, promoting a culturally relevant learning experience. Priority is given to middle schools, encouraging greater participation in STEM+CS education among Native students.