Best Grants for 501(c)(3) in South Carolina

The Pizza Hut Foundation is offering scholarships for students demonstrating financial need and community leadership. Eligible applicants must be U.S. residents aged 17-26, enrolled in accredited post-secondary education for Spring 2026, and maintain a minimum GPA of 2.5. Scholarship amounts range from $500 to $5,000, with distribution to be made in Spring 2026. The application period runs from July 8 to September 5, 2025, with notifications for recipients by November 17, 2025.

The Community Foundation of the Rappahannock River Region

The Community Foundation is a devoted advocate for the vitality and well-being of the Rappahannock River Region. We are a 501(c)(3) nonprofit that manages and distributes charitable giving in the counties of Stafford, Spotsylvania, King George, and Caroline, and the City of Fredericksburg.

Scholarships

One of The Community Foundation’s strategies for preserving and growing the quality of life in our region is supporting higher education for area students. Generous individuals and families, companies and organizations establish endowed scholarship funds and the proceeds from these funds benefit deserving students. Donors work with foundation staff to determine appropriate criteria for each fund. The Community Foundation currently administers more than fifty scholarship funds.

The Craig “Cujo, Jr.” Bennett Scholarship Fund

Established in June 2015, the Craig “Cujo, Jr.” Bennett Scholarship is awarded to a graduating senior who has excelled in the face of adversity. This scholarship was established in memory of Craig Daniel Bennett, known as Cujo, Jr – a reference to his father’s flight call sign and to the way a seemingly harmless and vulnerable young person could grow into a passionate and powerful individual. Challenged by extensive multiple physical issues, he defied the negative predictions of skeptical doctors again and again. Craig sometimes encountered people who had difficulty seeing past his wheelchair to who he really was – for them he was a source of surprise and, once his dynamic personality made itself known, a source of inspiration. Craig was a goal-oriented fighter who whitewater rafted the New River and was elected Homecoming King at Bluefield College. He had dreams of walking to receive his diploma and of sky diving.

Craig wanted to be seen as “normal”. Those who knew him saw more than that, he was extraordinary.

Knowing that his life expectancy was shorter than average, Craig asked his parents to establish a scholarship in his memory. Craig Daniel was the recipient of a Bootstrap Scholarship, which is given to nominees that demonstrate the effort and will to succeed in the face of adversity. Award winners are chosen by how well they demonstrate the concept of "pulling yourself up by your bootstraps." The Craig “Cujo, Jr.” Bennett Scholarship Fund also recognizes a student who uses determination and force of will to overcome odds, to meet hardship and to succeed in achieving their dreams.

The NIH StrokeNet initiative invites applications for clinical trials and biomarker studies aimed at stroke treatment, recovery, and prevention. This funding opportunity encourages collaborative projects that validate promising interventions and scientific aims within the NIH StrokeNet framework. Key deadlines for submissions span from February 2025 to November 2026, with support provided by the National Coordinating Center and Regional Coordinating Centers to ensure efficient study implementation and participant recruitment.

This grant aims to enhance applied regulatory science research for the evaluation and treatment of cardiotoxicity associated with oncology therapeutics. The initiative will facilitate collaboration with the FDA to develop effective methodologies and solutions, ensuring that research outcomes are directly relevant to regulatory decision-making. Key activities include regular communication with funded investigators and a focus on improving detection and management of cardiotoxicity, ultimately leading to impactful publications and presentations.

Society of Toxicology

Founded in 1961, the Society of Toxicology (SOT) is a professional and scholarly organization of scientists from academic institutions, government, and industry representing the great variety of scientists who practice toxicology in the US and abroad. The Society’s mission is to create a safer and healthier world by advancing the science and increasing the impact of toxicology. SOT operates under four guiding principles:

• Serving the needs of the scientific discipline and our members to enhance human, animal, and environmental health.
• Life-long learning and intellectual scientific stimulation.
• Diversity of representation in all activities of the Society.
• Integrity.

MDCPSS Early Career Achievement Award

Description

The MDCPSS Early Career Achievement Award recognizes the research accomplishments of young scientists in the early stages of their careers who have demonstrated excellence in toxicological research related to medical devices and/or combination products.

Award Categories

Up to two award recipients will be selected:

• One undergraduate or graduate student
• One postdoctoral fellow or early-career scientist (≤5 years post-graduation)

Award Recognition

• Each recipient will receive a plaque and a monetary award to support travel to the SOT Annual Meeting.
• Awardees will be recognized at the MDCPSS Reception and invited to give a 5-minute overview presentation of their work.

The AGA Abstract Award for Health Disparities Research provides a $500 travel grant for graduate students, medical students, residents, clinical fellows, and postdoctoral fellows who present research on health disparities at Digestive Disease Week® (DDW). This award aims to enhance interest in gastroenterology research and improve access to care for underserved populations. It recognizes outstanding abstracts accepted by AGA, fostering future careers in digestive disease research among young professionals.

The Community Foundation of the Rappahannock River Region

The Community Foundation is a devoted advocate for the vitality and well-being of the Rappahannock River Region. We are a 501(c)(3) nonprofit that manages and distributes charitable giving in the counties of Stafford, Spotsylvania, King George, and Caroline, and the City of Fredericksburg.

Scholarships

One of The Community Foundation’s strategies for preserving and growing the quality of life in our region is supporting higher education for area students. Generous individuals and families, companies and organizations establish endowed scholarship funds and the proceeds from these funds benefit deserving students. Donors work with foundation staff to determine appropriate criteria for each fund. The Community Foundation currently administers more than fifty scholarship funds.

Linda and Billy Beale Scholarship

The Linda and Billy Beale Scholarship Fund was created to support charitable projects in the community that has been home to their family for many years. Friends and colleagues know Linda and Billy as individuals who are deeply engaged in the fabric of the region – and especially Caroline County – through the business community, through their civic and social lives, and through their family’s involvement in their church and schools.

When thinking about a focal point for their charitable giving through this scholarship fund, the Beale’s were drawn to the school athletic “families” that have meant so much to them and their children over the years. Billy served as assistant baseball coach from 1999 to 2003 and Linda served as assistant volleyball coach from 1998 to 2006. The family also has history of involvement with Caroline Little League that began when their son played t-ball in the 1980’s and continued through their daughter’s service as a board member as an adult. The Beale's continue to show their support by participating in Little League special events today.

About The Children’s Heart Foundation

The Children’s Heart Foundation (CHF) is the country’s leading national organization solely dedicated to funding congenital heart defect (CHD) research. The mission of The Children’s Heart Foundation is to fund the most promising research to advance the diagnosis, treatment, and prevention of congenital heart defects. Since its inception, CHF has funded millions of dollars of CHD research across the U.S. and Canada. 

AHA/CHF Congenital Heart Defect Research Awards

The Children’s Heart Foundation partners with the American Heart Association to fund Congenital Heart Defect Research Awards. This collaborative investment of funds provides support for investigators who are actively conducting research directly related to advancing the prevention, diagnosis, and treatment of CHDs, which directly aligns with The Children's Heart Foundation's mission. 

Congenital Heart Defect Funding Opportunities

A multi-year commitment between the American Heart Association (AHA) and Children’s Heart Foundation (CHF) jointly supports Predoctoral Fellowship or Postdoctoral Fellowship investigators actively conducting basic, clinical, population, or translational congenital heart defects research.

Postdoctoral Fellowship

Purpose

To enhance the training of postdoctoral applicants who are not yet independent. The applicant must be embedded in an appropriate investigative group with the mentorship, support, and relevant scientific guidance of a research mentor. Recognizing the unique challenges that clinicians, in particular, experience in balancing research and clinical activity, this award mechanism aims to be as flexible as possible to enable applicants to develop academic careers in research alongside fulfilling clinical service commitments.

The trainee and mentor should collaboratively provide a thoughtfully planned, systematic proposal aimed at clearly answering an investigative question in cardiovascular, cerebrovascular or brain health research

• AHA research awards are limited to U.S.-based non-profit institutions, including medical, osteopathic, and dental schools, veterinary schools, schools of public health, pharmacy schools, nursing schools, universities and colleges, public and voluntary hospitals andothers that can demonstrate the ability to conduct the proposed research.

• Applicants must be AHA Professional Members at the time of proposal submission. The AHA expects all mentors associated with training/mentored research awards to maintain active AHA membership, as well.

• This award is not intended for individuals of faculty rank.

Applicants are not required to reside in the United States for any period before applying for American Heart Association funding. However, applicants must have one of the following designations at the time of proposal submission – not award start date, depending on career stage and each individual’s situation. An awardee must maintain one of the designations listed below throughout the duration of the award. Please consult with your institution’s grant officer.

• U.S. citizen
• Permanent resident
• Pending permanent resident (must have filed Form I-485 for permanent resident status and obtained an I-797C 3 Notice of Action that the application has been received by USCIS and case is pending)
• E-3 Visa - specialty occupation worker
• F-1 Visa – student (for predoctoral and postdoctoral fellows only)
• G-4 Visa - family member of an international organization employee
• H1-B Visa - temporary worker in a specialty occupation
• J-1 Visa - exchange visitor (pre- and postdoctoral fellowships only; all other awardees must obtain an H-1B or equivalent by the award activation date)
• O-1 Visa - temporary worker with extraordinary abilities in the sciences
• TN Visa - NAFTA Professional
• DACA - Deferred Action for Childhood Arrivals

The Lane E. Warren Scholarship Fund, managed by the Northern Piedmont Community Foundation, offers a $1,000 award to a Madison County resident who is a high school graduate or graduating this year. This scholarship honors Lane E. Warren, a promising student whose life was tragically cut short. The selection criteria emphasize financial need and community service, supporting students pursuing college or certificate programs in their educational endeavors.

The Lois R. Snead Arts & Crafts Scholarship Fund, managed by the Northern Piedmont Community Foundation, supports students in Rappahannock County who are pursuing education in arts or crafts. Eligible applicants must be graduating high school seniors and demonstrate community service and academic initiative. Priority is given to first-generation students in financial need, ensuring that local talent can thrive in creative fields. This scholarship reflects the Foundation's commitment to fostering community and artistic growth.

The AO Spine NA Young Investigator Research Grant Award supports early-career surgeons and researchers focusing on clinically relevant spinal or spinal cord research. With funding of $20,000, this initiative encourages new investigators by providing essential start-up capital. Successful applicants are required to present their findings at the Annual AO Spine North America Fellows Forum and submit progress and final reports detailing their research outcomes. This grant aims to foster innovation and excellence in spinal care.

Nearly a decade ago, HCLTech Grant was launched by the HCLFoundation to enable cross-sector collaboration and empower non-governmental organizations (NGOs) to play a decisive role in building a stronger, future-ready India. Today, HCLTech Grant has invested nearly $18 million in groundbreaking projects and is recognized as one of the largest grant programs in India—impacting over 27,000+ villages across 22 states and 2 UT's

HCLTech Grant for Climate Action in Americas Edition III

The future of cross-sector climate collaboration

We’re proud to bring our learnings and innovations from India to the Americas. As part of our global CSR strategy, we’ll start by investing $5 million over five years to impact-focused, Americas-based NGOs to supercharge their replicable, scalable and sustainable climate action projects. As a $13.7 billion technology company with over 218,000 people worldwide, our mission is to bring together the best of technology and people to supercharge progress for our clients, our people, our communities and our planet.

We’re looking to supercharge innovative, replicable, scalable and sustainable climate solutions. If the work you do fits the following criteria, our mission is to amplify your impact:

Prerequisites

• The organization’s bylaws should expressly permit engagement in purpose-driven projects and, where relevant, climate action initiatives, in accordance with the legal regulations of the country of registration.
• The proposed project must be designed for direct implementation by the applicant organization. Sub-granting of HCLTech funds is not allowed.
• The grant amount must not be used solely for infrastructure development / purchase of fixed assets like land, buildings, and vehicles, among others. Further, proposed infrastructure development costs must be spent in line with project objectives and activities defined.
• The applicant organization, including its governing body members, must not have any pending litigations.
• The applicant organization must not be blacklisted by any government agency, department, ministry, donor or international agency.
• The organization must not have faced cancellation of its license, registration or membership from the country-specific regulatory or statutory body.
• The applicant organization or its board members or employees must not have any political or religious affiliations.

Three organizations will be selected each year—first place will receive $500,000 and two runners-up will receive $250,000 each for a two-year project.

The Lucas Allen Erin’s Elderberries Scholarship Fund, established by a local entrepreneur, supports Fauquier County High School students pursuing their career goals. This $1,000 award requires applicants to be in good academic standing, demonstrate initiative, and provide a letter of recommendation from their employer. Priority is given to those exhibiting financial need and a work history. Managed by the Northern Piedmont Community Foundation, this fund aims to empower local students and enhance their educational journeys.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Eleanor C. Hungar Scholarship Endowment Fund

This fund was established to administer a bequest from the estate of Eleanor Hungar.

Miss Hungar (1905-2005) attended Greenman Elementary School. She was a graduate of West Aurora High School and Illinois State University at Normal. Miss Hungar was a beloved and greatly admired teacher. She had a profound influence on the children whose lives she touched.

To this day, former students fondly recall her extraordinary kindness to those who had the good fortune to learn at her side.

In keeping with her lifelong devotion to children, she bequeathed a portion of her estate to provide scholarships for students entering the field of elementary education.

The monetary value of each scholarship award varies depending upon the amount available in each individual scholarship fund. The most common scholarship award amount is $1,000 for a single year. Scholarships are designated as non-renewable one-year awards or renewable multi-year awards depending upon the scholarship fund criteria, as established by the donor of the scholarship fund.

The National Swine Resource and Research Center (NSRRC) is a pivotal resource that enhances biomedical research by providing genetically modified models. This centralized facility reduces variability and costs for researchers, allowing them to focus on scientific discovery. NSRRC offers breeding, cryopreservation, and genotyping services, ensuring consistent access to high-quality models. By consolidating these resources, it promotes reproducibility and supports the development of innovative methodologies in research, ultimately advancing our understanding of human health and disease.

Bass Pro Shops & Cabela's Outdoor Fund supports conservation-focused nonprofits through fundraising events and donation of merchandise or gift cards. Organizations eligible for funding must be registered 501(c)(3) entities in the U.S. or provincially registered nonprofits in Canada. This initiative aims to connect communities to outdoor activities while promoting wildlife conservation and support for military veterans. Grants of up to $1,000 are available to enhance local fundraising efforts.

The Klingenstein Third Generation Foundation's 'Transformation of Mental Health Care Program' seeks innovative research into improving mental health care access for children and adolescents, particularly from under-resourced backgrounds. Applications are invited for studies that build on promising pilot work, focusing on scalable delivery models and technology use. Eligible applicants are academic researchers based in the U.S. who can demonstrate rigorous research capabilities. The foundation plans to award up to two grants of $100,000 each year for two years.

Welcome to the Greater Houston Community Foundation Scholarship Application Site!   

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Scholarship Application Info:  

Greater Houston Community Foundation administers over 60 different scholarship programs, each with differing eligibility requirements. Eligibility for some scholarships may be dependent on employment, course of study, high school, or college. 

William A. Brookshire Foundation Scholarship

The William A. Brookshire Foundation Scholarship benefits dependents of S&B Engineers and Constructors employees.

About the Scholarship Award:

Multiple scholarships awarded for the 2026-27 academic year. Award amount varies by college/degree type:

• Bachelor's or Graduate Degree: Up to $15,000
• Associate's Degree: $5,500
• Students may reapply as long as they meet eligibility requirements

What can this scholarship be used for?

The scholarship will be mailed directly to the student's college to be used towards tuition, required academic fees, and/or book expenses.

Are there any requirements I must meet if I am selected as a scholarship recipient?

• Recipients must attend an accredited university, community college, or trade school in the United States.
• Recipients must enroll in the following hours for both the fall and spring semesters (or be enrolled full-time according to your school if it is on a different system) unless in the last semester prior to graduation
  • Minimum of 12 hours per semester for undergraduate students
  • Minimum of 9 hours per semester for graduate students
• Recipients must submit college enrollment information online through GHCF Scholar the summer before the academic year begins. This information is required in order for the scholarship check to be mailed to the student's college. Instructions will be included in the student's award letter.

The Mary Beth Williams Memorial Scholarship, managed by the Northern Piedmont Community Foundation, honors the life of Mary Beth Williams, who tragically passed away in 1997. This scholarship supports students from Rappahannock County with a minimum GPA of 2.5, demonstrating financial need, and pursuing higher education in agriculture or related fields. Award amounts vary, reflecting the foundation's commitment to fostering educational opportunities in the community.

Community Foundation of Northwest Missouri

The Community Foundation of Northwest Missouri Inc. was established in 2009 as a 501(c)3 public charity to help donors support their favorite charities while receiving maximum tax advantage.

We serve as a vehicle for charitable giving, helping donors give to the causes they care about. Donor gifts will strengthen nonprofits increasing programs and services. 

McLaughlin, Delbert & Mary Teaching Scholarship

This fund was established in memory of Delbert and Mary McLaughlin by their son, Bill McLaughlin to provide academic scholarships to graduating seniors of the St. Joseph School District pursing a degree in Education.

HCLTech Grant Edition II focuses on impactful climate action by investing $5 million over five years to support NGOs in the Americas. This initiative aims to enhance sustainable projects that align with the 17 Sustainable Development Goals (SDGs). With a history of significant contributions in India, HCLTech is committed to achieving net-zero emissions by 2040 and fostering innovative solutions to address pressing climate challenges. The grant encourages collaboration and aims to transform communities through effective climate action.

Community Foundation of Northwest Missouri

The Community Foundation of Northwest Missouri Inc. was established in 2009 as a 501(c)3 public charity to help donors support their favorite charities while receiving maximum tax advantage.

We serve as a vehicle for charitable giving, helping donors give to the causes they care about. Donor gifts will strengthen nonprofits increasing programs and services. Individuals and organizations are encouraged to establish a fund with us. 

St Joseph School District Foundation Tarpley, Bill Scholarship

This fund was established in honor of Bill Tarpley, who served as Principal of Central High School by his family and friends. The fund provides graduating seniors with a learning disability an opportunity to attend vocational school or college.

Guidelines:

• One scholarship will be awarded on a one-time basis and disbursed in August.

Amount:

• No less than $300 depending on available funds.

The Bay Area Lyme Foundation's Emerging Leader Award supports innovative research in Lyme disease, offering two $150,000 grants to post-doctoral and early-career scientists. Applicants are encouraged to propose proof-of-concept projects that enhance diagnostics or therapeutics. The award seeks to attract talent and foster scientific leadership in biomedical sciences. Evaluation criteria include the potential for novel therapies, scientific rationale, and support from institutions. This opportunity is ideal for those new to tickborne disease research.

The John and Olive Cornellisson Scholarship Fund, managed by the Greater Salina Community Foundation, supports students graduating from USD 239 or 240 high schools pursuing higher education in agriculture or vocational training. Open to high school seniors, current college students, and non-traditional students, the fund emphasizes financial need over GPA. Previous recipients can apply for renewal, ensuring continued support for those striving to advance their education.

The MBF Small Grants Program supports conservation projects for monarch butterflies and their habitats, primarily in Mexico. It aims to fund initiatives focusing on habitat conservation, scientific research, education, and sustainable development. Grants are primarily awarded to Mexican organizations and individuals, with a preference for those with relevant experience. Projects should enhance local livelihoods and promote environmental awareness within the Monarch Butterfly Biosphere Reserve.

Susan G Komen Breast Cancer Foundation

The mission of Susan G. Komen® is to save lives by meeting the most critical needs in our communities and investing in breakthrough research to prevent and cure breast cancer.

Susan G. Komen Career Catalyst Research (CCR) Grants

Susan G. Komen Career Catalyst Research (CCR) Grants foster promising breast cancer researchers who are in the early stages of their faculty careers by providing support for up to three years of “protected time” for research career development under the guidance of a Mentor Committee. We seek to support those who will emerge as the next key leaders in the fight against breast cancer.

CCR Research Focus: Research projects must be hypothesis-driven, breast cancer-focused studies. They may be considered basic, translational, clinical and/or population science in nature and should align with Komen’s research priorities and mission to save lives from breast cancer. 

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders

There remains a scientific gap in understanding of the role of anti-TFPImediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Funding

• Individual projects requesting up to $50,000 USD will be considered. Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.
• Maximum project length is 1 year.