Best Grants for 501(c)(3) in South Carolina

The Cooperative Endangered Species Conservation Fund supports habitat conservation through land acquisition grants. Established in 1997, this program aims to minimize conflicts between listed species conservation and land use. The U.S. Fish and Wildlife Service provides matching grants to state agencies for projects that ensure the long-term protection of habitats. By acquiring land or conservation easements, this initiative facilitates species recovery and helps prevent future listings under the Endangered Species Act, enhancing overall ecosystem health.

The National Fish Passage Program (NFPP) offers vital assistance for removing barriers to aquatic life, enhancing safety, and promoting local economies. By investing in projects like culvert replacements and floodplain restorations, the program not only supports native fish populations but also delivers significant economic benefits, estimated at $1.5 million for every $1 million invested. With a recent allocation of $15 million, including $5 million for specific restoration initiatives, NFPP continues to advance aquatic connectivity nationwide.

The Charles Hamlin Scholarship, established by Nurses Educational Funds, Inc., supports professional nurses pursuing master's or doctoral degrees in nursing. Applicants must hold a current RN license and demonstrate a commitment to nursing leadership, particularly in orthopedic care and the well-being of Native American communities. The scholarship honors Dr. Charles Hamlin's legacy, emphasizing the importance of cultural sensitivity in healthcare and preventing burnout among healthcare professionals. This award aims to empower future nursing leaders and enhance diversity in the field.

Nurses Educational Funds

Nurses Educational Funds, Inc. depends solely on donations to advance our only mission, to promote nursing leadership through annual scholarship support for professional nurses seeking masters and doctoral degrees in nursing education, practice, research, and administration.

NEF’s only purpose is to provide nursing scholarship assistance to make graduate level nursing education possible. NEF is one of the largest, national, private, professionally endorsed source of funds for advanced nursing study with over one hundred years of service to and for professional nursing. NEF is a non-profit organization with 501(c) status.

Rita Reis Wieczorek Scholarship for Maternal-Infant and Pediatric Nursing

Created in 2020, by Rita Reis Wieczorek, EdD, RN, PNP, FAAN, together with NEF. Dr. Wieczorek is an NEF Board Member Emeritus and longtime board member. This scholarship is the first NEF Scholarship to focus on maternal-infant and pediatric nursing. For over four decades Dr. Wieczorek has devoted her career to providing the best maternal-infant and pediatric care to her patients as well as teaching the highest standards of care to master's and doctoral nursing students, motivating them to excel in their care for the well-being of mothers, infants and children.

Alkermes

At Alkermes, we apply our deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders, including addiction, serious mental illness and sleep disorders. With our portfolio of marketed medicines and investigational pipeline candidates, we seek to make a meaningful difference in the way people manage these chronic diseases. Our patient-inspired science, integrated research strategy, sophisticated development capabilities and specialized commercial infrastructure enable us to pursue the development and commercialization of innovative new medicines, including those for people with conditions that have traditionally been overlooked or stigmatized.

Our greatest strengths at Alkermes are our people and our inherent empathy for patients, families and caregivers. Neurological and psychiatric disorders strike people at the core of who they are and impact many facets of their lives. We work with urgency to develop new treatment options for people living with these conditions.

Pathways APN Research Awards

The Alkermes Pathways Advanced Practice Nurse (APN) Research Awards™ program is designed to empower the advanced practice nursing community by offering funding opportunities that recognize their vital role in evidence-based care and the advancement of mental health research.

The Alkermes Pathways APN Research Awards provide opportunities for individual grants of up to $10,000 per project for licensed psychiatric-mental health nurse practitioners who are actively engaged in clinical, academic, and/or community health settings and are committed to advancing research in schizophrenia or bipolar I disorder.

RRCU Gives Foundation Grant

Mission Statement:

RRCU Gives strengthens our region by providing meaningful financial support to nonprofits addressing hunger, housing, and financial education. Through our annual grant awards and major funding initiatives, we help local organizations grow, thrive, and create lasting change.

 We award grants annually, with applications in June and awards in August.

Focus Areas

• Hunger
• Housing
• Financial Education

The AISES Indigenous Peoples Education Fund (IPEF) Scholarship offers $5,000 to support Indigenous students pursuing degrees in STEM fields. This scholarship is available to current AISES members who are full-time students and enrolled citizens or descendants of recognized Native American tribes. AISES aims to empower these students, fostering diversity in STEM while recognizing the importance of education as a tool for personal growth and community development.

About Colin Farrell FoundationThe Colin Farrell Foundation is committed to transforming the lives of individuals and families living with intellectual disability through education, awareness, advocacy, and innovative programs. Inspired by his two sons, he is excited and deeply humbled by the hope that the Colin Farrell Foundation can help those who the larger systems of governance have neglected.

CFF Innovation GrantsWe’re looking for bold, scalable solutions focused on one or more of these priority areas:

• Affordable co-housing models for individuals and families
• Employer-partnered day programs and inclusive job opportunities
• Tools and technologies that enhance accessibility at home and in community spaces
• Cross-sector collaborations between public, private, and nonprofit organizations

The Jerry and Martha Taylor Memorial Scholarship, offered by the Quad Cities Community Foundation, supports students from Rock Island County pursuing post-secondary education. With awards of up to $1,000, this scholarship is not renewable and is open to applicants with a minimum GPA of 2.75. Preference is given to students majoring in journalism, theater arts, or special education, or those attending accredited trade schools.

The Indigo Oak Fund's Education Grant Program supports educational initiatives in Colorado and the Bay Area, focusing on both traditional schools and alternative learning experiences. This program aims to empower individuals through education, fostering personal growth and lifelong learning. By funding resources for teachers and career advancement for adults, the Fund seeks to create equal opportunities, enhance community engagement, and contribute to a more equitable society.

The Cancer Prevention and Control Programs aim to enhance cancer outcomes by funding partnerships among national, state, territorial, and tribal organizations. These initiatives focus on evidence-based strategies for cancer surveillance, prevention, and control, specifically targeting breast and cervical cancer screening for underserved populations. Through collaboration, the program seeks to improve clinical services and cancer survivorship, ultimately striving towards the vision of 'All People Free of Cancer' by leveraging resources and community involvement.

The 1890 Institution Teaching, Research, and Extension Capacity Building Grants Program aims to enhance the capabilities of eligible institutions by fostering collaboration with federal and non-federal entities. This initiative supports the White House's commitment to promote excellence at Historically Black Colleges and Universities (HBCUs). By strengthening institutional teaching, research, and extension capacities, the program helps ensure that HBCUs can effectively contribute to innovative solutions in education and community development.

The Jane Bruckel Early Career Investigator Award in Axial Spondyloarthritis, offered by the Spondylitis Association of America, aims to support MDs and PhDs at the Instructor or Assistant Professor level in the US and Canada. This annual $30,000 research grant promotes innovative research in ankylosing spondylitis and enhances patient care by encouraging emerging researchers to contribute to this important field.

In 2025, the Community Foundation of Madison & Jefferson County awarded over $233,000 in scholarships to graduating seniors of the county’s public and private high schools. Nearly 50 different students earned money toward their college costs. Scholarships are available for a variety of applicants. Some are specific to schools, majors, need, or interests.

CFMJC scholarships may be used for tuition and related expenses like fees and required equipment at accredited colleges and universities. Room and board are not covered.

Madison Chautauqua Scholarship for the Arts in Memory of Bob Fourhman

Criteria evaluated:

• Letter of recommendation and artwork samples

Required materials:

• Letter of recommendation from a person knowledgeable about your talent and accomplishments in your art form; and
• An uploaded sample of your work (maximum 3 photos or 1 short video/audio clip)

Scholarship amount:

• $1,200 | 1 scholarship

The Juliette P. Doster Scholarship Fund honors the legacy of Mrs. Doster, who dedicated forty years to improving healthcare in Calhoun County. This renewable scholarship supports students pursuing associate's or bachelor's degrees, as well as approved workforce training programs. Awarded yearly for up to four years, recipients must maintain academic standards. Funding varies based on the Community Foundation's annual income, and the award covers tuition, housing, supplies, and other educational expenses.

The Lotte Lenya Competition, established in 1998 by the Kurt Weill Foundation for Music, honors the legacy of renowned actress Lotte Lenya. This unique contest blends acting and vocal skills, targeting performers aged 19-32 from diverse backgrounds. Celebrating its 25th anniversary in 2023, the competition has increased its prize offerings, with over $1.6 million awarded to more than 800 singers. It's a prestigious platform that has propelled many winners to successful careers in musical theater and opera.

The Patient-Centered Outcomes Research Institute (PCORI) will announce the Phased Large Awards for Comparative Effectiveness Research on December 2, 2025. This funding aims to support high-quality, patient-centered comparative clinical effectiveness research projects. The initiative encourages applicants to engage with patients and stakeholders to address critical healthcare dilemmas and improve decision-making. Projects should compare established clinical alternatives with evidence of efficacy, targeting vital health issues across diverse populations.

The Cynthia and Alan Baran Fine Arts and Music Scholarship Fund, established by passionate artists Cynthia and Alan Baran, aims to support young individuals pursuing their dreams in visual arts and music. This fund, administered by the Community Foundation of Middle Tennessee, offers scholarships to rising college students majoring in Fine Arts or Music, emphasizing the importance of creativity and academic achievement. With a commitment to fostering talent, this initiative empowers future generations to thrive in the arts.

This funding opportunity aims to advance HIV/AIDS research by implementing human new approach methodologies (NAMs) to reduce the reliance on specific pathogen free (SPF) animal models. It emphasizes the integration of NAMs-enabled frameworks for in vitro testing while supporting essential SPF colony resources. The initiative seeks to enhance research rigor and reproducibility through innovative strategies that prioritize human-relevant models, ultimately improving HIV research outcomes and facilitating collaborative development in the field.

Carl Hill Memorial Scholarship

Awards:

• One time award of $500.

The Stem Cell Grants: Travel Award supports students, postdocs, and faculty attending scientific conferences and workshops related to stem cell research. Up to $1,200 is available for each application, with a maximum of two applications per PI lab each calendar year. Priority is given to those presenting at stem cell meetings and workshops. All applications must be submitted at least one week before travel to ensure funding consideration.

The Cardiovascular & Pulmonary Research Grants aim to support impactful research that enhances cardiovascular and pulmonary health through physical therapy interventions. This grant emphasizes studies that assess patient characteristics, improve health outcomes, and address disparities. Research proposals must align with the 2023 APTA Research Agenda and prioritize clinical relevance, employing various investigative designs. The goal is to foster innovative approaches that significantly reduce cardiovascular disease risks and improve patient care in the U.S.

The Elevance Health Foundation's Food as Medicine Grant aims to enhance access to nutritious foods and improve health outcomes for individuals facing diet-related conditions. This initiative invites qualified nonprofits to submit proposals focused on scalable solutions that address food insecurity and promote health equity. The foundation prioritizes programs that demonstrate measurable outcomes and support whole-person health, particularly for populations at high social risk. Grants will be awarded for a term of 1-3 years, with funding based on program needs.

Indigo Hope Foundation: At-Risk Youth Development Grant

Empowering programs that provide mentorship, education, life skills training, and opportunities for young people facing challenges.

Key Focus Areas:

• Mentorship Programs
• Educational Support
• Life Skills Training
• Career Development

Example Programs We Fund:

• After-school tutoring and mentorship
• Job readiness training
• Leadership development

Jack Kent Cooke Foundation

The Jack Kent Cooke Foundation is dedicated to advancing the education of exceptionally promising students who have financial need. Since 2000, the Foundation has awarded $304 million in scholarships to more than 3,400 students from 8th grade through graduate school, along with comprehensive academic advising, career pathway counseling and other support services. The Foundation has also provided $136 million in grants to organizations that serve such students.

The Jack Kent Cooke Foundation’s scholarship programs are designed to encourage and support outstanding students who work hard and have financial need. Our scholarships provide financial assistance and academic support to high school, undergraduate, and graduate students. In addition to the monetary award, students join a thriving network of more than 3,400 Cooke Scholars.

Young Scholars Program

The Cooke Young Scholars Program is a selective five-year, pre-college scholarship for exceptionally promising 7th grade students with financial need. It provides comprehensive academic and college advising, as well as financial support for school, Cooke-sponsored summer programs, internships, and other learning enrichment opportunities.

Program Experience

Educational Advisers support Young Scholars to maximize high school experiences and to go on to thrive at the nation’s top-performing colleges. Our programming and support may include:

• Identifying an appropriately rigorous high school.
• Engaging in four-year planning and goal-setting.
• Funding for academic and extracurricular opportunities, such as music and art lessons, supplemental academic classes and technology.
• Annual summer programs, including two required Young Scholar programs.
• Year-round Young Scholars community programming.
• Networking opportunities with a high-achieving peer community.

The Curriculum and Instruction Honor Award, presented by SHAPE America, recognizes outstanding contributions to health and physical education curriculum research. This prestigious award highlights the importance of effective instructional practices that prepare students for active and healthy lives. Award recipients are selected based on their scholarship in health education and physical education, demonstrating commitment to excellence since the organization's founding in 1885. SHAPE America advocates for quality education and promotes the well-being of preK-12 students across the United States.