Best Grants for 501(c)(3) in South Carolina

The RRF Foundation for Aging offers research grants aimed at improving the well-being of older adults and their caregivers. Established in 1950, the foundation has awarded over $239 million to support innovative projects nationwide. Grants are targeted at nonprofit organizations proposing research with immediate implications for adults aged 60 and older, with a focus on practical knowledge and dissemination to impact policy and practice.

The CFSI Education Fund Scholarship, offered by the Community Foundation of Southern Indiana, awards multiple $2,000 non-renewable scholarships to students over 25 who have some college experience but no degree. This program aims to support those returning to complete their post-secondary education, including vocational training. By empowering individuals from Clark and Floyd counties, the scholarship fosters educational advancement and community growth, reflecting the foundation's commitment to enriching lives through learning.

The Reverend Pinckney College Readiness Program assists high school students in Beaufort, Charleston, Colleton, Hampton, and Jasper counties with college preparation. This 18-month program supports first-generation college students and those with financial needs, ensuring they have the resources to navigate the college application process. Participants receive personalized coaching on standardized tests, financial aid, and scholarship applications, promoting academic success and civic engagement. Named after Rev. Clementa Pinckney, the program fosters ambition and mentorship among its students.

The NINDS Alzheimer’s Disease-Related Dementias (ADRD) K99/R00 program promotes diversity by supporting new independent investigators from underrepresented backgrounds in AD/ADRD research. This award facilitates a transition from mentored postdoctoral positions to independent faculty roles, providing essential NIH research support. Applicants must propose research that does not involve leading a clinical trial but may include participation in trials led by mentors. Key deadlines for applications span from October 2024 to June 2027.

The Bertin Family Foundation Grants support 501(c)(3) public charities that align with the foundation's mission of community strengthening and compassion. Grant requests are accepted annually from July 1 to August 31, focusing on program or project support rather than general endowment. The foundation values measurable outcomes and responsible stewardship, and gives preference to organizations with Gold or Platinum status on Candid.

The Department of Defense Research and Education Program aims to support Historically Black Colleges and Universities and Minority-Serving Institutions by enhancing defense-related research and educational capabilities. This initiative encourages collaboration with other educational institutions and government organizations to increase STEM graduates and strengthen national defense. Eligible applicants include accredited minority institutions and community colleges. The program is open until July 31, 2029, providing a significant opportunity for institutions meeting the defined criteria.

Honor Grants

Supporting organizations that serve victims and families.

Our Honor Grant program provides financial support to 501(c)(3) nonprofits that offer services to victims and families impacted by heinous crimes. Awarded quarterly, these grants help organizations continue vital work in some of the hardest moments families will ever face.

• Grants up to $20,000, with occasional consideration for larger requests
• Open year-round to eligible organizations
• Funding supports a wide range of programs and projects, with a focus on those that are innovative, impactful, and built for long-term sustainability

This funding opportunity announcement (FOA) aims to support research that advances the development of medical products for preventing, diagnosing, treating, or curing ALS and other rare neurodegenerative diseases. The FDA seeks to address critical knowledge gaps and significantly impact these diseases through this initiative, which targets both adult and pediatric populations. By funding these studies, the FDA hopes to inform current and future product development in this vital area of healthcare.

The ASTRO-AstraZeneca SCLC Therapy Challenge RFP aims to enhance research on limited-stage small cell lung cancer (LS-SCLC) through innovative combination therapies, particularly integrating immunotherapy with advanced radiation techniques. Proposals are encouraged to explore various aspects, including care patterns, treatment workflows, prognostic biomarkers, and toxicity management. The target budget for projects ranges from $175,000 to $375,000, with consideration given to higher requests based on scientific merit, fostering significant advancements in radiation oncology.

The Health Equity and Inclusiveness Research Fellow Award by LUNGevity supports physician-scientists conducting lung cancer research aimed at addressing health disparities. Funded projects will focus on early detection and improved outcomes for lung cancer, particularly among underserved communities. Awards can reach up to $100,000 over two years, with payments contingent on project milestones. This initiative aims to foster innovative research and enhance individualized treatment approaches for lung cancer.

The Learning Bridge Foundation aims to empower individuals caught in poverty and discrimination by providing scholarships for education and job training. Focused on Oklahoma, the foundation offers support to those with limited financial resources or prior incarceration. Scholarships, typically ranging from $2,500 to $6,000, cover tuition and supplies, with potential funding for Bachelor’s Degrees in unique cases. Through targeted activities, the foundation seeks to break the cycle of crime and poverty, granting second chances for a better future.

This funding opportunity by the FDA aims to enhance education and public awareness regarding the risks associated with skin lightening products, such as hydroquinone. The initiative encourages innovative, community-based strategies that engage stakeholders in promoting health equity. Proposals should focus on outreach activities that strengthen the scientific understanding of these products while addressing public health concerns. This is a vital step in ensuring safer use and informed consumer choices.

The Marlene and Spencer Hays Foundation Grants support tax-exempt organizations working to enhance lives through arts, healthcare, education, and youth programs. The foundation requires a Letter of Intent (LOI) from all applicants, emphasizing its mission to select grant recipients who align with its values. Grants are not available for political purposes, endowment campaigns, or organizations that discriminate based on race, gender, or religion. This framework ensures a focused impact on community betterment.

The First Solar Community Giving Fund, managed by the Grand Strand Chapter of the South Carolina Native Plant Society, supports local projects focused on native plants. This nonprofit organization, based in Conway, offers grants up to $1,500 to encourage community involvement in conservation efforts. The Grand Strand Chapter aims to fund 3 to 4 projects that align with its mission of protecting and educating about native plant species.

The Hearing Health Fund, part of Sweet Relief Musicians Fund in collaboration with Sweetwater, aims to support musicians and music industry professionals facing hearing difficulties. This initiative addresses the auditory risks inherent in the music industry due to exposure to loud sounds. Eligible applicants must demonstrate financial need and prove that a significant portion of their income comes from music-related work, ensuring that assistance reaches those most affected by hearing challenges.

The Cooperative Agreement aims to enhance the dissemination of clinical practice guidelines, particularly those developed through FDA-supported initiatives. Applicants are encouraged to devise a comprehensive strategy for creating, evaluating, and distributing materials that promote effective dissemination, with a strong emphasis on equity in healthcare access. This initiative seeks to ensure that vital clinical information reaches diverse populations, ultimately improving health outcomes across communities.

The NIA Advanced Postdoctoral Career Transition Awards aim to enhance diversity in the translational research workforce for Alzheimer's disease and related dementias (AD/ADRD). This initiative supports early career researchers from diverse backgrounds in acquiring essential research skills applicable to various AD/ADRD studies. The goal is to cultivate a more diverse pool of researchers capable of leading interdisciplinary approaches in treatment, prevention, and management of AD/ADRD. Notably, independent clinical trials are not permitted under this award.

The BioMarin Grant aims to support events, activities, and projects that enhance public health and benefit patients with rare diseases. This corporate funder focuses on scientific innovation and provides resources for organizations such as hospitals, universities, and patient advocacy groups. With an emphasis on education and community support, BioMarin encourages applications for funding throughout the year, ensuring timely assistance for eligible projects.

The American Heart Association (AHA) offers Student Scholarships in Cardiovascular Disease to encourage research among students in health-related fields. Open for applications starting January 27, 2025, these scholarships provide $2,000 for student projects focused on cardiovascular and cerebrovascular diseases. The top awardee will be named the Howard S. Silverman Scholar, receiving an additional $1,000 stipend. AHA membership is required by April 3, 2025, to apply.

The American Heart Association offers $2,000 scholarships for students researching cerebrovascular disease and stroke. These funds are paid directly to the recipient's institution. Additionally, scholarship winners may qualify for a $750 travel grant to attend the International Stroke Conference, provided they present an accepted co-authored abstract. Eligibility includes being a member of the AHA and studying in accredited programs focused on cardiovascular disease.

Small Steps in Speech is offering Individual Grants for Speech Therapy, Therapeutic Summer Camps, or Assistive Devices. Effective February 2, 2024, families with a joint household income of up to $125,000 can apply. Eligible applicants are U.S. citizens aged 3-22. Grants are not solely based on financial need, and previous grant recipients from SSIS may not reapply. Detailed eligibility and application requirements are outlined to ensure fair access to necessary support.

The NIA Expanding Research in AD/ADRD Postbaccalaureate Research Education Program aims to enhance the research workforce by providing intensive research experiences for recent graduates. This initiative supports early-stage investigators in Alzheimer's Disease and related dementias, addressing a critical shortage of researchers in the field. Participants engage in independent research, mentorship, and professional development, equipping them with skills necessary for advanced degrees and research careers in aging and dementia. The program fosters innovation and interdisciplinary collaboration essential for advancing AD/ADRD research.

Pediatric Dermatology Research Alliance Inc 

PHACE syndrome is a neurocutaneous syndrome characterized by large segmental infantile hemangiomas of the face and scalp in association with congenital anomalies that may affect the posterior fossa of the brain, cerebral and cervical arteries, heart, and/or eyes. LUMBAR syndrome is the lower-body counterpart of PHACE, characterized by large segmental infantile hemangiomas of the lumbosacral, buttock or pelvic regions associated with urogenital, spinal, bony, anorectal, and/or renal abnormalities. Those affected experience a wide range of comorbidities with significant psychosocial impact. We invite proposals for clinical research that improves diagnostic approaches, enhances quality of life, and addresses key aspects of disease burden and management.

Applications may be submitted by either a single investigator or multiple investigators at multiple institutions. A total of $40,000 is available and may be awarded as one large-scale project or as multiple smaller awards, depending on the number and quality of applications received. Equal consideration will be given to projects in either of the two award formats with decisions to be based upon merit and available funds.

Focus

Research should focus on PHACE and/or LUMBAR syndromes. Priority will be given to investigators who have not previously served as the senior investigator on an R01 NIH grant or equivalent, and to studies that include multidisciplinary teams with active roles for early-career investigators. Proposals that meaningfully integrate patient perspectives are strongly encouraged.

Important Details

• Up to $40,000 will be funded to support one large-scale project for up to two years, or as multiple awards for smaller-scale projects

In 2020, GradGuard founded College Life Protected, LLC as a social purpose entity that supports programs, research, professional development, and best practices in higher education that promote greater confidence in the value of higher education as a public good. 

College Life Protected invites the higher education community to apply for grants that are consistent with our mission.

Promoting Financial Literacy

College Life Protected recognizes that that financial literacy is a critical skill for student success, impacting everything from academic persistence to long-term financial well-being. That’s why we are committed to funding programs and initiatives that equip students with the knowledge and resources they need to make informed financial decisions.

By supporting programs that enhance financial education, we aim to empower students to navigate college costs, manage personal finances, and build a strong financial future.

About

Mission, Vision & Values

To enhance our community through philanthropy.

We aspire to co-create diverse, meaningful and innovative charitable giving that yields an exponential positive impact within local communities and beyond.

Coopey Boys’ Memorial Fund

About the fund

The Coopey Boys, Raymond Peter and Lauritz Martin, were born with hemophilia, a genetic disorder that impairs the body’s ability to make blood clots. Sadly, they both died at an early age. The Coopey Boys’ Memorial Fund benefits Corvallis students who suffer from a physical handicap or serious chronic health problem.

Who We Are

The Community Foundation of Central Illinois will make a sustainable philanthropic impact in our community through visible leadership in connecting people who care with causes that matter.

Joyce and Thomas H. Stanisic Scholarship Fund 

The Joyce and Thomas H. Stanisic Scholarship Fund was established to award scholarships based on need to students working toward a degree or certification in the music or healthcare fields. This scholarship will be given for the entire expected course of study, up to 4 years.

About Pfizer

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement, or education) to improve patient outcomes in areas of unmet medical need that are aligned with medical and/or scientific strategies.

About the American Headache Society

The American Headache Society strives to improve the lives of people impacted by migraine and other headache disorders. The AHS is a professional society of health care providers dedicated to the study and treatment of headache and face pain. The Society’s objective is to promote the exchange of information and ideas concerning the causes and treatments of headache and related painful disorders. Educating physicians, health professionals, and the public while encouraging scientific research are the primary functions of the Society.

Quality Improvement and/or Research Grants: Migraine and Women’s Health

Migraine is a prevalent and debilitating neurological disease that disproportionately affects women, impacting quality of life, productivity, and overall health. Recognizing the need for innovative solutions and enhanced care, Pfizer and the American Headache Society (AHS) are collaborating to offer a new grant opportunity inviting proposals for collaborative quality improvement and research projects focused on migraine and women's health. This Request for Proposals (RFP) aims to foster high-impact research and initiatives that advance scientific understanding, improve patient outcomes, and address gaps in care. Projects should also contribute to the core goal of the AHS – improving the lives of people impacted by migraine and other headache disorders.

Objectives

• To advance research in migraine and women's health through collaborative pre-clinical and clinical projects
• To promote quality improvement initiatives that enhance diagnosis, treatment, and management of migraine in women
• To encourage multidisciplinary approaches that integrate clinical expertise, patient-centered care, and innovative research methodologies
• To generate measurable and actionable outcomes that contribute to improved standards of care and inform future research directions for women with migraine