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Best Large Grants for Nonprofit Organizations in South Carolina

Find the perfect Large Grants for Nonprofit Organizations in South Carolina on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in South Carolina in the United States.

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$3.79B

Total funding

$5K

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9,000+ grants
$3.79B total
$5K median

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NACBS Undergraduate Essay Prize

The North American Conference On British Studies Inc
Private
Canada, United States
US $100
The NACBS Undergraduate Essay Prize, awarded by The North American Conference on British Studies, recognizes outstanding essays on British topics from undergraduates at U.S. and Canadian universities. Each year, up to eight prizes of $100 are given, encouraging submissions from diverse fields including History, English, and Cultural Studies. This initiative aims to promote scholarly engagement with British Studies, fostering a deeper understanding of its historical and cultural contexts during the 2023-24 academic year.
Anthropology & Cultural Studies Writing & Literature European Art +1 more

#GaryInspiredMe Scholarship for Lackawanna County

Scranton Area Foundation Inc
Private
United States
Unspecified amount

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a graduating senior from a high school in Lackawanna County who demonstrates academic excellence, good citizenship, participation in athletics, and who is active in a faith or religious-based organization.

Education - Higher Education Religion & Spirituality Sports & Athletics +1 more

NRA Sybil Ludington Women's Freedom Award

The NRA Foundation, Inc
Private
United States
Unspecified amount

About The NRA Foundation

The heart of The NRA Foundation’s mission is preserving the core of our American values and traditions in our steadfast effort to Teach Freedom.

The NRA Foundation Supports Freedom, Family, and the Future of the Shooting Sports

Established in 1990, The NRA Foundation, Inc. (“NRA Foundation”) is a 501(c)(3) tax-exempt organization that raises tax-deductible contributions in support of a wide range of firearm-related public interest activities of the National Rifle Association of America and other organizations that defend and foster the Second Amendment rights of all law-abiding Americans.

The heart of The NRA Foundation’s mission is preserving the core of our American values and traditions in our steadfast effort to Teach Freedom.

Established in 1990, The NRA Foundation, Inc. (“NRA Foundation”) is a 501(c)(3) tax-exempt organization that raises tax-deductible contributions in support of a wide range of firearm-related public interest activities of the National Rifle Association of America and other organizations that defend and foster the Second Amendment rights of all law-abiding Americans. These activities are designed to promote firearms and hunting safety, to enhance marksmanship skills of those participating in the shooting sports, and to educate the general public about firearms in their historic, technological and artistic context. Funds granted by The NRA Foundation benefit a variety of constituencies throughout the United States including children, youth, women, individuals with physical disabilities, gun collectors, law enforcement officers, hunters and competitive shooters.

Awards

The NRA is proud to recognize the contributions of those who have demonstrated dedication to the promotion of the Second Amendment, significantly impacted the preservation of the shooting sports, advanced the purposes and goals of the NRA and exemplified leadership through public service. Each year, women, youth, clubs, law enforcement officers and NRA Foundation volunteers are awarded for their efforts in pursuit of these principles.

NRA Sybil Ludington Women's Freedom Award

This national award is in honor of the brave woman, Sybil Ludington, who in 1777, galloped on her horse one night to rally troops against the British. Now to honor her accomplishment and the accomplishments of modern heroines, the NRA bestows the prestigious Sybil Ludington Women’s Freedom Award in her name.

Sport Shooting Community / Public Safety Gun Violence Prevention

Connecting Champions for Diversity, Equity, Inclusion, and Belonging in the Health Professions

Robert Wood Johnson Foundation
Private
United States
Up to US $2,000,000

About RWJF

At the Robert Wood Johnson Foundation, we take bold leaps to transform health in our lifetime and pave the way, together, to a future where health is no longer a privilege, but a right. We take our responsibilities seriously, and pledge to work in ways that reflect our values.

Connecting Champions for Diversity, Equity, Inclusion, and Belonging in the Health Professions

RWJF seeks to fund one lead organization or consortium to serve as a national network-weaver for diversity, equity, inclusion, and belonging (DEIB) in the health professions. The selected grantee will connect and support leaders, organizations, and institutions across the ecosystem, strengthening relationships, aligning strategy and communications, and facilitating shared learning and collective action. By building the connections and infrastructure needed for collaboration, the grantee will help advance belonging, accountability, and systems change across health professions education and healthcare institutions.

Achieving a healthcare system grounded in equity requires both a diverse health professions workforce and institutions committed to advancing diversity, equity, inclusion, and belonging (DEIB). While diverse teams improve quality of care and health outcomes, RWJF has learned that increasing representation alone is insufficient without addressing structural and institutional barriers that shape belonging, leadership, advancement, and accountability. Structural racism and other forms of systemic inequity continue to limit opportunity across the health professions education and healthcare institutions.

Lasting change requires not only supporting diverse leaders, but also strengthening connections among educational institutions, healthcare organizations, professional associations, accrediting and credentialing bodies, students, advocates, community actors, and others within the health professions ecosystem, whose relationships, actions, practices, and mindsets shape health outcomes for the communities they serve. These relationships create the support, trust, shared learning, and coordinated action necessary to advance DEIB and build a more equitable healthcare system. 

Economic Services & Development Community Development & Revitalization Diversity, Equity & Inclusion +1 more

Donaghue Foundation: Greater Value Portfolio Grant Program

Patrick and Catherine Weldon Donaghue Medical Research Foundation
Private
United States
Up to US $500,000
The Donaghue Foundation's Greater Value Portfolio Grant Program aims to enhance healthcare value by funding innovative research projects for two years, with awards up to $400,000. It encourages proposals that address issues such as high costs, disparities, and inefficiencies in care. Eligible applicants include Ph.D. researchers at nonprofit institutions partnered with healthcare organizations. The program seeks actionable solutions to improve patient care and reduce the burden of low-value healthcare on communities.
Health Care Access & Delivery Health & Medicine Health Policy & Advocacy +1 more

Alexandra Hallock Capacity Building Grant for Small Nonprofits

Cause Strategy Partners
Corporate
United States
US $20,000
The Alexandra Hallock Capacity Building Grant for Small Nonprofits, established in 2024, honors the legacy of Alexandra Hallock by supporting small nonprofits focused on human rights, women's empowerment, and LGBTQ+ causes. This grant offers a one-time $20,000 unrestricted funding along with pro-bono capacity building support. It aims to strengthen organizational infrastructure and governance, ensuring impactful community engagement. Eligible organizations must be 501(c)3 nonprofits with revenue under $400,000, operating for at least one year, and based in the U.S.
Social Justice / Human Rights Sexuality & LGBTQIA+ Rights Women's Rights & Equality

Climate Program Office (CPO) FY2026 Earth System Science and Services Partnership

National Oceanic and Atmospheric Administration (NOAA)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Climate Program Office (CPO) FY2026 Earth System Science and Services Partnership (ESSSP) aims to enhance NOAA's mission through collaborative research and activities. It focuses on understanding changes in Earth's systems and their impacts on ecosystems and communities. Eligible applicants include academic institutions offering doctoral degrees in NOAA-related sciences. The total funding available is approximately $10 million, supporting initiatives that encompass research, data evaluations, and stakeholder engagement.
Earth Science Atmospheric Sciences Climatology +1 more

Beekhuis Scholarship

Delaware Community Foundation
Private
United States
US $4,000

Beekhuis Scholarship

Award:

  • One time award of $4,000.
Mathematics Education - Higher Education Science +3 more

M.A. Essay Prize

The North American Conference On British Studies Inc
Private
Canada, United States
US $500
The M.A. Essay Prize, awarded by the North American Conference on British Studies (NACBS), recognizes exceptional original research by students in stand-alone M.A. programs in the U.S. and Canada. With a prize of $500, it encourages scholarly excellence and invites winners to submit their work for publication. Faculty nominations are required, ensuring deserving candidates receive recognition for their academic contributions, thereby fostering a vibrant academic community within British studies.
Anthropology & Cultural Studies Writing & Literature European Art +1 more

Volk – Geyman Scholarship

San Juan Island Community Foundation
Private
San Juan County, Washington
Unspecified amount
The Volk – Geyman Scholarship, established by the San Juan Pilots Association, honors John Volk and John Geyman by providing financial assistance to students pursuing careers in aviation and medicine. This scholarship aims to support high school graduates with a commitment to academic excellence and community service. Eligible fields include aviation-related studies and emergency medical training. By fostering leadership and service, the scholarship encourages students to follow the inspiring examples set by its namesakes.
Aviation Astronomy & Astrophysics Engineering +4 more

Katie Cannon Scholarship

Presbyterian Mission Agency
Private
United States
Up to US $3,000
The Katie Cannon Scholarship honors Rev. Dr. Katie Geneva Cannon, a pioneering figure in the Presbyterian Church (U.S.A.). This scholarship aims to empower Presbyterian women of color, clergywomen, and college women by providing financial assistance for leadership development events and educational opportunities. It promotes spiritual growth and mission involvement within the church, ensuring that women are equipped for greater service and leadership roles. This fund is part of the Women's Ministry Fund at the Presbyterian Mission Agency.
Presbyterianism Women & Girl Services Civic Leadership Development +1 more

Judith R. Walkowitz Article Prize

The North American Conference On British Studies Inc
Private
Canada, United States
US $1,000
The Judith R. Walkowitz Article Prize, awarded annually by the North American Conference on British Studies, recognizes the best published article addressing gender and sexuality in British culture. This prize honors Professor Walkowitz’s significant contributions to the fields of gender and cultural studies. Open to scholars in North America, it encourages diverse perspectives across disciplines and time periods, with a cash award of $250 to support ongoing research and scholarship in British Studies.
Anthropology & Cultural Studies Writing & Literature European Art +1 more

John Ben Snow Prize

The North American Conference On British Studies Inc
Private
Canada, United States
US $500
The John Ben Snow Prize, awarded by the North American Conference on British Studies, recognizes the best book by a North American scholar focusing on British Studies from the Middle Ages to the eighteenth century. This prestigious annual award includes a $500 prize and encourages authors who are U.S. or Canadian citizens or permanent residents to submit their works. Nominations can be made by authors or publishers, with discretion advised for multiple entries.
Anthropology & Cultural Studies European Art European History +1 more

Lindsey Fields Allied Health Education Award

National Association of Biology Teachers
Private
United States
US $500

About NABT

Since its establishment in 1938, the National Association of Biology Teachers (NABT) has been the recognized "leader in life science education." Thousands of educators have joined NABT to share experiences and expertise with colleagues from around the globe; keep up with trends and developments in the field; and grow professionally.

NABT Mission

The National Association of Biology Teachers empowers educators to provide the best possible biology and life science education for all students.

Lindsey Fields Allied Health Education Award

Established to honor Lindsey Fields, this award recognizes innovative, student-centered classroom instruction that supports an understanding in the diverse fields that comprise allied health sciences (Ex. Human A&P, Pre-Nursing/Med, Pathology, etc.). This award is sponsored by NABT, and includes a $500 honorarium. The recipient also receives a recognition plaque to be presented at the NABT Professional Development Conference and one year of complimentary membership to NABT. 

Education - Higher Education Biology Human Anatomy +1 more

John M. O'Quinn Foundation Grant

John M Oquinn Foundation
Private
United States
Unspecified amount
The John M. O'Quinn Foundation Grant, established in 1986, has contributed over $192 million to various charitable activities, focusing primarily on Houston and its surrounding areas. The Foundation supports tax-exempt organizations and governmental units, emphasizing conservation, education, healthcare, and programs for underprivileged youth. Grants are not available for type III supporting organizations, individuals, or foreign charities, ensuring a targeted impact within the local community.
Education Environmental Conservation Youth Services +1 more

CFCC: Mark C. and Dorothy I. Morgan Scholarship

Greater Salina Community Foundation
Private
United States
US $1,500 - US $2,000

Our mission is to enhance quality of life, today and in the future, by:

  • Enabling donors to fulfill their charitable desires
  • Building a permanent endowment
  • Facilitating prudent management and care of funds
  • Meeting needs through grants, awards, and scholarships

CFCC: Mark C. and Dorothy I. Morgan Scholarship

Amount

(1) $2,000 scholarship, (2) $1,500 scholarships

This scholarship is not renewable and previous recipients may not reapply.

Education Education - High School Agricultural Education

CRSJ Racial Justice in Education Grant

National Education Association Staff Organization
Private
United States
US $5,000 - US $75,000
The CRSJ Racial Justice in Education Grant, administered by the National Education Association, aims to enhance racial equity within education by funding initiatives that promote awareness, leadership development, and solidarity among diverse racial groups. Grants typically range from $10,000 to $75,000, supporting projects that address racism and foster equitable policies in educational settings, thereby accelerating efforts towards social justice.
Social Justice / Human Rights Education - K through 12 Diversity, Equity & Inclusion +1 more

Spight Family Foundation Grants

The Spight Family Foundation
Private
United States
Unspecified amount
The Spight Family Foundation Grants aim to enhance the well-being of families and support environmental initiatives that benefit future generations. They welcome charitable organizations that align with their mission, regardless of location, with a primary focus on Northern California. By funding various projects, the foundation seeks to foster community health and sustainability, making a lasting impact on both local and global scales.
Environmental Conservation Environment Family Services +1 more

OneStar AmeriCorps VISTA Project

The Onestar Foundation
Private
United States
Unspecified amount

Who We Are

OneStar strengthens Texas communities by creating pathways for individuals and organizations to engage, connect, and accelerate their impact.

OneStar AmeriCorps VISTA Project

OneStar AmeriCorps VISTA Project places skilled individuals with a diverse range of backgrounds at nonprofits and agencies throughout the state of Texas. AmeriCorps VISTA members serve full-time for one year on capacity-building projects to advance your organization’s anti-poverty mission.

OneStar AmeriCorps VISTA Project places community-driven individuals with nonprofits & agencies throughout Texas on transformative projects focused specifically on building organizational capacity and infrastructure to alleviate poverty. Get the support you need to accelerate your efforts in volunteer management, marketing, community outreach, fundraising, program development, and more!

Capacity building activities include:

  • Volunteer Engagement
  • Fundraising & Development
  • Communication & Marketing
  • Community Engagement & Outreach
  • Program Development

Economic Services & Development Poverty Alleviation & Services Community Development & Revitalization +2 more

SC Ministry Foundation: Annual Grants

SC Ministry Foundation
Private
United States
Unspecified amount
The SC Ministry Foundation provides annual grants aimed at supporting nonprofit organizations aligned with the mission of the Sisters of Charity of Cincinnati. These grants can be used for core programs, planning, and program expansion. Eligible organizations must demonstrate financial sustainability and avoid duplication of services. The application process starts with a pre-application survey, and funding decisions are typically made by June 30. Priority is given to projects in education, healthcare, and social services.
Social Justice / Human Rights Education Health Care Access & Delivery +2 more

The Hendrix-Murphy Book Award

Hendrix-Murphy Foundation
Association/Society
United States
Unspecified amount

Hendrix-Murphy Foundation

Enhancing literature & language at Hendrix College since 1978.

In homage to Bertie Wilson Murphy’s passion for the study and appreciation of literature and language, the Hendrix-Murphy Foundation at Hendrix College was founded in 1978 with an endowment by her son, Charles H. Murphy, Jr., former CEO of Murphy Oil Corporation. Mrs. Murphy was a 1905 graduate of Galloway Women’s College in Searcy, Ark., which merged with Hendrix College in Conway in the 1930s. Charles H. Murphy, Jr., was a member of the Hendrix Board of Trustees and served as chair. 

The Foundation's programs are overseen by a Board of Directors that is headed by the president of the College and includes Murphy family members, the provost, and representatives from the Hendrix Board of Trustees.

The Hendrix-Murphy Book Award

Hendrix is proud to offer the Hendrix-Murphy Book Award to an outstanding high school junior who demonstrates distinguished scholarship or leadership in literary studies (English, creative writing, foreign languages, or drama).

Hendrix-Murphy Book Award recipients will receive a copy of Poems to Read: A New Favorite Poems Anthology, edited by Robert Pinsky and Maggie Dietz.

Students may be nominated by their English, languages, creative writing, or drama teacher or guidance counselor by using the required form.

Writing & Literature Linguistics Language Education +1 more

Northern Lowcountry Grants: The Boeing Interfaith Fund

Coastal Community Foundation of South Carolina
Private
Berkeley County, South Carolina, Charleston County, South Carolina +1 more
Approximately US $5,000
The Boeing Interfaith Fund, established by Boeing South Carolina in 2024, aims to uplift faith-based outreach ministries in Charleston, Dorchester, and Berkeley Counties. Through this initiative, the Coastal Community Foundation supports vital community services such as education, health access, and economic mobility. By fostering collaboration among local organizations, the fund enables impactful outreach efforts that enhance the well-being of residents and address pressing community needs effectively.
Education Economic Services & Development Wellness & Healthy Living +1 more

The Karim Thomas Ziyad Memorial Engineering Scholarship Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Karim Thomas Ziyad Memorial Engineering Scholarship Fund supports students from Washington County or nearby areas pursuing a career in engineering, especially in Mechanical Engineering. Established in memory of Karim Thomas Ziyad, this scholarship aims to empower deserving students to achieve their educational goals. The fund is part of the Community Foundation of Washington County Maryland, which offers numerous scholarships to enhance educational opportunities for local students.
Education - Higher Education Mechanical Engineering Education - High School +1 more

Dennis Schuman Charitable Foundation Grant

Dennis Schuman Charitable Foundation
Private
United States
Unspecified amount
The Dennis Schuman Charitable Foundation Grant supports qualified Jewish organizations and charities in the United States, focusing on arts, education, health, human services, public benefit, and religion. Established by Dennis Schuman, the foundation continues his philanthropic legacy, providing funding exclusively for charitable, religious, scientific, literary, or educational purposes. Organizations must be exempt under Section 501(c)(3) of the Internal Revenue Code to qualify for funding.
Art & Culture Education Health & Medicine +5 more

OJJDP FY 2026 Internet Crimes Against Children On-Line Child Protection System (ICACCOPS)

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
Up to US $900,000
The OJJDP FY 2026 Internet Crimes Against Children On-Line Child Protection System (ICACCOPS) funding opportunity aims to enhance and maintain critical investigative tools for child exploitation cases. ICACCOPS provides a robust IT infrastructure to support data services, network security, and management tools for law enforcement. This initiative strengthens the efforts of the national network of ICAC Task Forces, which are dedicated to combating technology-facilitated child sexual exploitation across the United States.
Computer Science & Engineering Youth Services Crime & Justice +2 more

Bruce J. Heim Foundation Grant

Bruce J Heim Foundation
Private
United States
Unspecified amount
The Bruce J. Heim Foundation Grant supports organizations that empower young individuals with exceptional potential in academics and the arts. Established in 1986, this private foundation aims to provide financial assistance that fosters skill enhancement and personal growth. The Board evaluates grant requests monthly, assessing the viability and significance of each organization’s project. The Foundation's goal is to inspire recipients to realize their potential and contribute to philanthropic efforts, echoing the support they received.
Youth Services Human & Social Services Academic Success & Enrichment +1 more

Knight Cities Challenge

John S And James L Knight Foundation Inc
Private
Allen County, Indiana, Baldwin County, Georgia +24 more
Up to US $200,000

About Knight Foundation

John S. and James L. Knight believed that a well-informed community could best “determine its own true interests” and was essential to a well-functioning, thriving democracy. They pursued those beliefs, building and leading one of the largest and most successful newspaper companies in American history.

For 75 years, Knight Foundation has supported the people, ideas and insights that lead to thriving communities. The foundation invests in local journalism, arts and culture and community development in the 26 cities and towns where the Knight brothers once published newspapers.

Since our founding in 1950, we have been committed to the communities we serve and to providing those communities with the tools they need for residents to thrive.

Knight Cities Challenge

Knight Foundation is currently accepting applications for the Knight Cities Challenge, a $5 million open call inviting individuals and organizations across its 26 communities to submit new, creative ideas for projects that can spark change and leave a lasting local impact.

Building on a long history of open challenges across programs, Knight democratizes access to grantmaking to unlock the best and brightest ideas. This spring, KCC returns to invest in its first cohort of community-centered solutions to local challenges and help promising ideas take root and grow.

Project ideas must focus on at least one of Knight’s investment areas: strengthening local news and information, creating pathways for economic opportunity or cultivating connection through arts, culture and the places that bring people together.

You may submit one idea, either as an individual or on behalf of your organization. While you are limited to one application as the lead applicant, you may collaborate on other projects submitted by different partners. Each individual or organization may receive funding for only one project.

For large institutions such as universities or city governments, schools or departments are considered separate entities. 

Journalism News Media & Communications Economic Services & Development +1 more

Large Grants for Nonprofit Organizations in South Carolina Highlights

Looking for large grants for nonprofit organizations in South Carolina?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in South Carolina recommended for your specific programs.

Grant Insights : Large Grants for Nonprofit Organizations in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Large Grants for Nonprofit Organizations in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

54 Large Grants for Nonprofit Organizations in South Carolina over $25K in average grant size

41 Large Grants for Nonprofit Organizations in South Carolina over $50K in average grant size

32 Large Grants for Nonprofit Organizations in South Carolina supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in South Carolina supporting programs / projects

1,000+ Grants on Instrumentl focused on Health Care Access & Delivery

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
26.6%
Q3
24.1%
Q4
20.4%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$530,911 $530.9 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081