Best Large Grants for Nonprofit Organizations in South Carolina

The Wenatchee Exchange Club Scholarship, established by the Wenatchee Exchange Club in 1959, supports college-bound seniors from Wenatchee and Eastmont high schools. This scholarship is awarded to students demonstrating excellence in academics, athletics, or extracurricular activities, and community involvement. Preference is given to children or grandchildren of current or deceased members of the Exchange Club. Administered by the Community Foundation of North Central Washington, it aims to foster educational opportunities for deserving students.

The Cloutier-Valenti Legacy Scholarship, funded by the Delaware Community Foundation, offers a one-time award of $1,000 to graduating seniors from selected high schools in Delaware. Eligible students must enroll in an accredited institution, demonstrate financial need, and show involvement in community activities. The scholarship aims to support students pursuing degrees in science, contributing to the foundation's mission of enhancing educational opportunities and equity in the community.

The NIH StrokeNet initiative invites applications for clinical trials and biomarker studies aimed at stroke treatment, recovery, and prevention. This funding opportunity encourages collaborative projects that validate promising interventions and scientific aims within the NIH StrokeNet framework. Key deadlines for submissions span from February 2025 to November 2026, with support provided by the National Coordinating Center and Regional Coordinating Centers to ensure efficient study implementation and participant recruitment.

Medina County Women's Scholarship FundOriginally established by the American Association of University Women of Medina County to award scholarships to nontraditional female students. A nontraditional student is a woman whose undergraduate education has been interrupted or delayed.Amount:

• Varies

Number of awards:

• Varies

Renewal:

• Must reapply annually by submission of a new application; however, any applicant cannot be selected more than twice for this scholarship.

The Young Investigator Grants, offered by the Breast Cancer Alliance, aim to support early-career researchers focused on breast cancer. This two-year grant provides up to $125,000 in funding, split across the duration, to facilitate independent research projects. Applicants must be affiliated with U.S. institutions and should not have held major grant support previously. This initiative fosters innovation in breast cancer research, ultimately enhancing survival rates and quality of life for affected individuals.

This funding opportunity invites applications for pilot projects focused on understudied proteins linked to rare diseases. The goal is to generate preliminary data and tools related to these proteins, which belong to druggable families with known rare disease associations. By supporting innovative research, this initiative aims to facilitate the characterization of these proteins, ultimately contributing to advancements in understanding and treating rare diseases.

The ASTRO-LUNGevity Residents/Fellows in Radiation Oncology Seed Grant aims to advance the research careers of residents and fellows focusing on radiation oncology and its impact on lung cancer treatment. This $50,000 award supports innovative basic, translational, and clinical research projects. A no-cost extension may be granted at ASTRO and LUNGevity's discretion, but the total project duration cannot exceed two years.

Anne K. Petry Scholarship Fund

Established by Summit Education Partnership Foundation to provide scholarships for Akron Public Schools students studying special education.

Amount:

• $1,000

Number of awards:

• 1

Renewal:

• No

In 2025, the Community Foundation of Madison & Jefferson County awarded over $233,000 in scholarships to graduating seniors of the county’s public and private high schools. Nearly 50 different students earned money toward their college costs. Scholarships are available for a variety of applicants. Some are specific to schools, majors, need, or interests.

CFMJC scholarships may be used for tuition and related expenses like fees and required equipment at accredited colleges and universities. Room and board are not covered.

Dupont Alumni Scholarship

Criteria evaluated:

• Academic record, interview, and financial need

Required materials: 

• 2 letters of recommendation from teachers and/or counselors of the applicant’s high school; and 
• FAFSA SAI PDF upload

Scholarship amount:

• $3,900 | Multiple scholarships may be awarded

The Emerge Grant, established by the Jeannette Rankin Foundation, supports women and nonbinary individuals aged 25 and older from Georgia and Montana. With grants up to $2,500 annually, recipients can pursue technical, vocational, or degree programs at accredited U.S. institutions. This initiative, rooted in Rankin's legacy, aims to empower those demonstrating financial need. Applicants will be informed about their status, ensuring transparency in the selection process.

The PATH Scholarship, established by the Ellucian Foundation in 2020, aims to support higher education institutions in assisting students facing financial hardships. With over $2.9 million awarded, it has benefited more than 3,100 students. Eligible institutions can receive grants ranging from $10,000 to $25,000, with individual awards up to $1,500. This initiative encourages public two-year colleges, particularly Minority Serving Institutions, to apply and adapt award criteria to meet the needs of their students.

Who We Are

The Community Foundation of Central Illinois will make a sustainable philanthropic impact in our community through visible leadership in connecting people who care with causes that matter.

Vietnam Veteran’s Moving Wall Fund

The Vietnam Veteran’s Moving Wall Fund Scholarship was established to support the children of local veterans who served in the Vietnam War or subsequent conflicts. It was created in 1990 by the Vietnam Veteran’s Moving Wall Committee using remaining funds originally raised to bring the National Vietnam Veteran’s Moving Wall Exhibit to Glen Oak Park in Peoria, Illinois. The exhibit honors the 58,126 Americans who lost their lives during the Vietnam War.

Who We Are

The Community Foundation of Central Illinois will make a sustainable philanthropic impact in our community through visible leadership in connecting people who care with causes that matter.

MidAmerica National Bank’s Employees Children Scholarship Fund

The MidAmerica National Bank’s Employees Children Scholarship Fund was established in 2005 by MidAmerica National Bank to provide scholarship support to the children of bank employees. It is open to students graduating from high school or currently enrolled in an undergraduate college or vocational program.

The SDA Award of Excellence recognizes innovative achievements in textile and fiber arts, promoting the mission of the Surface Design Association (SDA). This prestigious award is presented to artists exhibiting exceptional work in current exhibitions, emphasizing creativity and excellence. Recipients receive a one-year premium digital membership in SDA, which includes various member benefits. By celebrating artistic accomplishments, the award aims to enhance awareness of the SDA's commitment to supporting textile and fiber artists and their contributions to the community.

The Breast Cancer Alliance offers Exceptional Project Grants aimed at enhancing survival rates and quality of life for individuals affected by breast cancer. This grant, amounting to $100,000 over one year, supports innovative research and projects in the contiguous United States. Eligible applicants include clinical doctors and research scientists at any career stage. The funding covers salary and project costs, with indirect costs capped at 8% of direct costs, ensuring comprehensive support for impactful research.

Jacqueline Hall Minet Travel Award for Cross-Cultural Understanding

To provide financial assistance to a Brighton High School student or a Rochester City School District high school student so that he or she can participate in a travel experience that offers significant opportunities for involvement in a foreign-language culture.

Number and Size of Awards

Number of recipients and award amounts vary; maximum $2,000.

Allowed Use of Award

Awards may be used for expenses associated with travel abroad programs.

The Project Lifesaver International Grant by the Alzheimer’s Foundation of America aims to fund programs that prevent wandering and enhance public safety for individuals with dementia-related illnesses. This grant supports public safety agencies that are members of AFA and Project Lifesaver International, focusing on essential training, supplies, and community outreach. Grants are awarded biannually, promoting better care and safety for individuals living with Alzheimer’s disease and related dementias.

The Lynches River Conservation Grant supports land acquisition and conservation projects aimed at enhancing water quality and ecological integrity in the Lynches River watershed of South Carolina. Funded by the Central Carolina Community Foundation, this grant prioritizes projects in specific service areas, with funding covering full costs for priority projects and up to 50% for expanded areas. Eligible applicants include 501(c)3 organizations and government entities, with a preference for accredited land trusts.

The Mission Scholarship, established by the Community Foundation of North Central Washington in 2007, supports graduating seniors from Chelan, Douglas, or Okanogan counties who plan to undertake mission trips to Latin America. This scholarship aims to inspire young individuals to engage in community service while gaining cultural insights. Eligible applicants must be juniors or seniors, ready to complete their mission within two years of receiving the award, providing a unique opportunity to make a positive impact abroad.

The Talati Family Scholarship Fund, administered by the Community Foundation of Western Massachusetts, aims to support students of color pursuing higher education. Students can apply through a single online application, which connects them to various scholarships based on eligibility. Awards can reach up to $3,000 and may impact financial aid offers. This scholarship is available to undergraduate and graduate students attending accredited institutions in the U.S., particularly those from Franklin, Hampshire, and Hampden Counties.

The William and Elizabeth Robinson Scholarship, offered by the Community Foundation of North Central Washington, supports graduating seniors from Chelan or Douglas county high schools who demonstrate significant financial need. Ideal candidates are hardworking, motivated students with a GPA between 3.3 and 3.80. This scholarship honors the Robinsons' legacy of valuing education and community service, assisting those who aspire to pursue higher education and contribute positively to society.

The Ogburn Family Scholarship, provided by the Community Foundation of North Central Washington, supports high school seniors from Quincy, Wenatchee, or Eastmont High Schools. Eligible students should plan to pursue education or a medical field, such as nursing or radiology, and maintain a minimum GPA of 2.5. Preference is given to those attending Wenatchee Valley College or Central Washington University's teaching program. This scholarship promotes educational advancement within the community.

The Jeannette Rankin National Scholar Grant supports women and nonbinary students aged 35 and older, providing up to $2,500 annually for technical or vocational education, associate’s degrees, or first bachelor’s degrees. This grant, renewable for up to five years, aims to empower those facing financial need, fostering better futures for American women. Recipients are selected based on their applications, ensuring that all candidates are informed about their status.

The Civic Engagement Microgrant Grant Program, funded by Research!America, aims to enhance public engagement skills among early-career scientists. By providing financial support for innovative projects, this initiative encourages collaborations across various STEM disciplines. Grantees will develop essential skills in communication and policy-making to strengthen community ties and promote science as a national priority. This program addresses the critical need for scientists to connect with local communities and policymakers to ensure the relevance and impact of scientific research.

The ASTRO-BCRF Emerging Investigator Award aims to support one early career researcher in breast radiation oncology from underrepresented populations. This initiative by the American Society for Radiation Oncology and the Breast Cancer Research Foundation provides $100,000 for direct costs over one year, emphasizing diversity in the scientific workforce and encouraging eligible individuals to self-identify as part of underrepresented groups in biomedical research.

The Anne & Irving Brodsky Innovation Grant, offered by the Alzheimer's Foundation of America, provides $25,000 to support innovative programs that enhance the lives of individuals affected by Alzheimer's disease and related conditions. This grant is exclusively available to AFA nonprofit member organizations, with funding directed towards essential program expenses such as staff training, administrative costs, and necessary supplies. The initiative aims to foster advancements in care and support for families dealing with Alzheimer's.

The NIH is seeking innovative computational approaches to enhance the curation of biomedical research assets at scale. This initiative aims to accelerate access to secure datasets and computational models, facilitating transformative discoveries in biomedical science. Key deadlines for applications range from January 2025 to January 2027, covering standard, renewal, and AIDS-related grants. Applicants are encouraged to submit Letters of Intent 30 days prior to application deadlines to ensure a streamlined review process.