Best Large Grants for Nonprofit Organizations in South Carolina

The Lymphoma Scientific Research Mentoring Program (LSRMP), offered by the Lymphoma Research Foundation, provides essential mentorship and education for clinical fellows and junior faculty focusing on lymphoma research. With two tracks, one clinical and one laboratory/translational, the program aims to cultivate research skills and foster collaborations. Participants will receive guidance on project development, statistical analysis, and grant submission, ensuring they are well-equipped for future research endeavors in lymphoma and chronic lymphocytic leukemia.

Mission & Vision

Rochester Area Community Foundation, in partnership with generous philanthropists and community partners, works to improve the quality of life for people who live and work in the eight-county region through its leadership and strategic grantmaking.

Our Mission:

We are cultivating a thriving Greater Rochester region — powered by philanthropy, grounded in community, and sustained across generations.

Our Vision:

We envision a Greater Rochester region transformed by enduring philanthropy, where every person, neighborhood, and future generation can thrive.

Dobe E. and Jacqueline C. Ulmer Scholarship

Purpose of Scholarship

For a graduating senior who is hard-working, focused, thoughtful, caring, selfless, and dedicated to continuous learning.

Number and Size of Awards

One award of $1,000; paid in one lump sum in the Fall and divided equally between the Fall and Spring semesters. A second award of $500 may also be given.

Casey's Cash for Classrooms Grants support K-12 public and nonprofit private schools through funding for physical improvements, material needs, teacher support, and community engagement. In 2025, $900,000 was awarded across 80 grants, allowing schools to enhance their learning environments. With a commitment to community engagement, Casey's has donated $15 million since 2019, emphasizing their dedication to making life better for communities and guests. Grants range from $3,000 to $50,000, with funds required to be used within 12 months.

The William H. Scheide Research Grants, established by the American Bach Society in 1990, support research on Johann Sebastian Bach and his contemporaries. With stipends ranging from $500 to $4,000, these grants are awarded annually and may cover travel and primary source reproduction costs. Preference is given to Ph.D. candidates and junior faculty, but senior faculty are also encouraged to apply. Each recipient receives a one-year membership in the Society, fostering further engagement with Bach's music.

The Disability Inclusion Fund Grant, managed by Borealis Philanthropy, aims to support organizations advocating for disability inclusion, rights, and justice. As a partner in philanthropy, Borealis facilitates donor collaboratives to maximize impact across various communities and movements. Organizations interested in applying for this grant are encouraged to review the detailed FAQ for further information. This initiative is a vital step towards fostering inclusivity and promoting the rights of individuals with disabilities.

The National Fish Passage Program (NFPP) offers technical and financial support to restore aquatic connectivity for fish and other organisms. By improving infrastructure like culverts and bridges, the program enhances fish populations and ecosystem resilience, providing quality fishing experiences. Managed by the US Fish and Wildlife Service, NFPP collaborates with partners to implement strategic projects that align with conservation goals, ensuring biological diversity and effective use of scientific principles in project planning.

Medina County Women's Scholarship FundOriginally established by the American Association of University Women of Medina County to award scholarships to nontraditional female students. A nontraditional student is a woman whose undergraduate education has been interrupted or delayed.Amount:

• Varies

Number of awards:

• Varies

Renewal:

• Must reapply annually by submission of a new application; however, any applicant cannot be selected more than twice for this scholarship.

The Gilead Foundation offers funding aimed at creating equitable health opportunities for all. Through its Giving Together Program and the Creating Possible Fund, it mobilizes resources to support community organizations that address health disparities and promote education equity. By fostering employee volunteerism and matching contributions, the Foundation actively engages in building healthier communities. This holistic approach seeks to dismantle barriers to health access, ensuring a sustainable impact on individuals and communities.

The Ralph M. Knight Chemistry & Engineering Scholarship, established in 2010 by Nancy Knight, honors her late husband, Ralph. This scholarship is aimed at full-time seniors in Catholic high schools within the Diocese of Phoenix who are practicing Catholics and U.S. citizens. Awardees receive a one-time $5,000 towards freshman-year tuition at a four-year college or university, provided they major in chemistry or engineering.

The Clinical and Translational Science Award (CTSA) Program invites applications to enhance clinical and translational science through innovative partnerships and research programs. This initiative aims to accelerate the delivery of treatments to diverse populations by improving clinical research efficiency, creating national resources for public health responses, and providing training for clinical research professionals. Applications are due by 5:00 PM local time, with optional Letters of Intent recommended 30 days prior to the full proposal deadline.

The I Could Do Great Things Foundation is dedicated to empowering individuals and organizations with innovative ideas that have a charitable purpose. By providing financial support and encouragement, the foundation aims to help transform great ideas into reality. There is no deadline for applications, making it accessible for anyone with a fresh approach to apply. The foundation prioritizes projects related to education, community, and Jewish causes, ensuring that the impact is meaningful and far-reaching.

The William Simes Research Fund, established in honor of Frances Simes Hastings, supports graduate students and postdoctoral researchers conducting field research at Hastings Natural History Reservation in California. Awards of $2,000 are available to offset costs related to housing and research supplies for extended research periods. This fund fosters scientific inquiry at one of the oldest field stations in the University of California Natural Reserve System, promoting the stewardship of diverse natural habitats.

The Ambler Trust Grants, provided by the Elizabeth Raymond Ambler Trust, support various sectors including education, health, arts, culture, and environmental initiatives. Eligible applicants include municipal, religious, charitable, benevolent, or educational organizations as determined by the Trustees. These grants aim to enhance community welfare and promote beneficial projects, ensuring a positive impact across diverse fields.

The Betty H. King Scholarship, offered by the Community Foundation of the Ozarks, provides two renewable $1,000 scholarships for female high school seniors from select Missouri counties. Eligible applicants must have a minimum GPA of 3.0, enroll in at least 12 credit hours, and plan to major in Education, Engineering, Math, or Science. Applications require a transcript, personal essay, and details about community service involvement.

The Russell Sage Foundation’s Core Research Grants program addresses social, political, and economic inequalities in the U.S. It investigates the factors contributing to these disparities and their impact on various outcomes, including education and civic participation. Launched in 2001 and renamed in 2018, the program aims to enhance understanding of how inequalities affect mobility and representation. Researchers with a doctorate or substantial experience are encouraged to apply, fostering high-level scholarly research in this critical field.

The Wan Chen and Ming Li Scholarship for International Study at WMU's College of Education and Human Development supports undergraduate and graduate students in non-English based study abroad programs. Applicants must be U.S. residents, enrolled in CEHD, and submit proof of acceptance into an international program along with a proposal outlining the experience's benefits for their academic and career goals. This scholarship aims to enhance educational opportunities and make studying abroad more accessible.

Promega Corporate Giving is dedicated to advancing science and improving life globally. With over 45 years of experience, Promega supports initiatives in science, education, and creativity, focusing on innovative solutions and community wellness. They fund organizations in the U.S. and Canada that prioritize experimental initiatives while steering clear of political, religious, and fraternal causes. Their commitment lies in fostering long-term contributions from scientists to meet future global needs.

The Kettering Family Foundation, established in 1956, supports diverse charitable activities across various sectors, including arts, education, health, and human services. Applicants must have a valid 501(c)(3) status and discuss proposals with foundation staff before applying. Only one application is allowed per year, and specific exclusions apply, such as for religious purposes and individual grants. The foundation emphasizes meaningful community impact, making it a vital resource for eligible organizations.

The Elizabeth Hurlock Beckman Award Trust Grant honors educators who inspire students to create impactful organizations or movements. Established in 2008, the trust has awarded over $3.5 million to 148 professors across the U.S. The grant primarily supports those teaching in psychology, medicine, or law, emphasizing the importance of community contribution. Eligibility is limited to U.S. citizens or permanent residents who have inspired their former students to make a difference.

The NRF Foundation Ray Greenly Scholarship supports students pursuing degrees in digital retail-related fields such as technology and supply chain. Established in memory of Ray Greenly, this scholarship aims to empower ambitious students with the creativity and entrepreneurial spirit to innovate in retail. Eligible candidates must be undergraduate students with a minimum GPA of 3.0 and relevant internship experience. The application deadline is November 3rd, providing a unique opportunity to attend the NRF Foundation Student Program in New York City.

NASA's Solar System Exploration Research Virtual Institute Cooperative Agreement Notice-5 invites multi-institutional proposals aimed at advancing human exploration of the Moon and Mars. This initiative focuses on innovative research to address critical scientific questions and develop technologies for future missions. The program emphasizes community development, training the next generation of scientists and engineers, and fostering partnerships to integrate science with exploration goals.

Community Foundation of New Jersey

Over our 46-year history, the Community Foundation of New Jersey has collaborated with individuals, families, organizations, and businesses to design charitable funds and implement the philanthropic solutions they want to see in their communities. We leverage $1.17 billion in assets and 1,200 funds to help our partners think boldly and creatively about ways to give.

Scholarship Fund Overview

Beyond a shared commitment to educational opportunity, families establish scholarship funds with a variety of goals and purposes in mind. They may offer traditional scholarships or customize fund awards for alternative scholarships.

Currently, CFNJ administers more than 135 scholarship funds. Our scholarship opportunities run the gamut, from those exclusive to a local high school or geographic region to those supporting specific majors or career pursuits. Last year, we awarded over $2 million in scholarship assistance to 271 scholars.

Applicants may be evaluated on academic performance; extracurricular activities; community involvement; paid or unpaid work; and a statement of their personal aspirations, educational goals, and demonstrated unmet financial need in our scholarship review process.

David H. Roe Scholarship

This scholarship assists graduating high school seniors from the Greater Newark area who plan to pursue an undergraduate degree in mathematics, physics, biology, botany, or chemistry. Applicants must have been accepted to a four-year accredited college/university within the United States and must be entering their freshman year in the fall. If you have not yet been accepted to a college or university, please do not apply at this time. Scholarships are based on merit and unmet financial need.

The FY 2027 DoN HBCU/MI Program aims to enhance the research capabilities of Historically Black Colleges and Universities and Minority Institutions. This initiative promotes innovative solutions to naval science challenges while engaging students and faculty in STEM fields. Key objectives include strengthening research infrastructure and fostering collaborative efforts across institutions. White papers are due by September 18, 2026, and should clearly outline the proposed advancements in naval-relevant science and technology.

The Northeast Asia Council Japan Studies Grants support American citizens and permanent residents conducting scholarly research on Japan within the U.S. Offering up to $2,500, including daily expenses, these grants aim to enhance the quality of teaching and research in Japanese studies. Eligibility includes being an AAS member and not having received funding in the last three years. Applications are reviewed based on project merit and financial need, prioritizing those with limited access to institutional funding.

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

Thomas William Bennett Memorial Scholarship Fund

He believed that a person could do anything if they sat down and read how to do it. When WWII started, he was the first man from the state of South Carolina to enlist in the U.S. Army. He quickly rose to captain and spent most of the war in the Pacific (the Queen of Fiji considered him a friend). Later, Thomas had a long career at Harcourt Brace publishing.

The Japanese American Community Foundation Grants support programs for the Japanese American and broader Asian American communities. Funding ranges from $2,500 to $50,000 for projects focusing on senior health, history, arts, culture, and youth. Eligible applicants must be registered 501c3 public benefit nonprofit organizations. Note that organizations with open grants cannot apply until their current grant is closed. Submit a Letter of Inquiry (LOI) before the full proposal.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Lee Shipman Engineering Scholarship

This scholarship has been made possible by the generosity of Lee Shipman who established the Lee Shipman Engineering Scholarship Fund of the Community Foundation for Mason County.

Lee Shipman has always had a love for all things electrical as far back as grade school when he added an additional phone in his family home so calls could be answered from more than one location! This eventually led him to get his degree in electrical engineering and a career at Dow Chemical in Ludington. He continued following his passion after retiring from Dow by working with a local Ludington business helping with the selection and modifications of equipment. Through this work, he recognized the real challenges that downtown merchants face. Lee is thankful for the people who have made a difference in his life, from his Latin teacher to coworkers to close friends and, because of this, he wants to give back to others. He established this Scholarship Fund for students pursuing electrical engineering.