Best Large Grants for Nonprofit Organizations in South Carolina

The Leonard Litz Foundation supports LGBTQ+ organizations through grants that promote health, wellness, crisis intervention, racial justice, advocacy, and social assistance. Priority is given to organizations in the northeast U.S. and those serving communities of color and transgender individuals. Applications that clearly link funding requests to specific needs will receive stronger consideration. The foundation aims to foster a supportive environment for the LGBTQ+ community to thrive.

The NIH's TALK initiative aims to enhance clinical practices for late talking children by funding research to identify early signs of language delays. This NOFO focuses on developing evidence-based strategies for screening and supporting children and their families. It targets children over 18 months who are not meeting language milestones, particularly those at higher risk due to various factors. Collaborative research efforts are encouraged to ensure effective identification and intervention.

The James L. Shriver Scholarship Fund, administered by the Community Foundation of Western Massachusetts, provides financial assistance to students from western Massachusetts pursuing technical careers. Eligible applicants include undergraduate or graduate students attending accredited post-secondary institutions in the U.S. Scholarships can reach up to $3,000 and may impact financial aid offers, so students should consult their college financial aid offices for guidance. This initiative supports diverse students aiming for technical fields.

U.S. Civil Society Microgrants

We seek to support projects that engage Pulitzer Center journalism to amplify the voices of affected communities, foster public debate, and drive meaningful audience engagement with our focus areas.

Audience engagement has been at the core of the Pulitzer Center’s work since its founding in 2006. In addition to grants and fellowships that facilitate breakthrough journalism, we support initiatives that connect the reporting to the audiences that need it the most. Our goal is pursuing real-world impact: engaging and mobilizing communities, increasing understanding and connection, and influencing decisions locally and globally. 

This microgrant aims to support civil society organizations and groups in the United States to utilize Pulitzer Center-supported reporting as part of projects that contribute to a more informed and empowered community.

 For this grant cycle, we are seeking grant proposals for civic engagement projects to be completed by early December 2026 that focus on one of the following issues:

• Climate and the environment, with a focus on U.S fisheries and fishing communities or climate and labor
• Information and Artificial Intelligence
• Global health, with specific focus on mental well-being or connections to the Global South

The objective is to use Pulitzer Center-supported journalism as the inspiration for the projects supported by this civil society microgrant. By leveraging this reporting, we expect to build projects that amplify the voices of affected communities, foster public debate, and drive meaningful audience engagement that will lead to impactful conversations in communities in the U.S. and beyond.

Grants range from US$2,000 to US$4,000. Project proposals can support existing activities or support the launch of new activities. 

Boom & Bucket's Student Scholarship Program aims to provide a $1,000 scholarship each year to students pursuing heavy machinery programs at colleges or trade schools in the U.S. and Canada. This initiative supports both current and future students, ensuring access to quality education regardless of financial background. By investing in education, Boom & Bucket hopes to foster the next generation of heavy equipment professionals while demonstrating its commitment to transparency and customer service.

The Energy, Power, Control, and Networks (EPCN) Program, managed by the National Science Foundation, fosters innovative research in multi-agent systems, resource allocation, and machine learning. It focuses on applications in energy, transportation, and robotics, while emphasizing the integration of renewable energy into power systems. EPCN also explores advanced power electronics, cybersecurity for grids, and the development of adaptive systems. This program encourages groundbreaking advancements in energy-efficient technologies and promotes collaboration in addressing complex challenges.

The Springfield Teachers Club Scholarship Fund, managed by the Community Foundation of Western Massachusetts, supports graduates of Springfield public high schools residing in Franklin, Hampden, and Hampshire Counties. The fund offers scholarships up to $3,000 to eligible students enrolling in accredited post-secondary schools. Applicants are advised to consult with their financial aid offices, as scholarship awards may affect financial aid packages. This initiative aims to promote educational opportunities for local students.

The Springfield Women’s Club Scholarship Fund, administered by the Community Foundation of Western Massachusetts, aims to support women over 19 from Hampden County pursuing two- or four-year degrees. Eligible students can apply through a single online application that matches them with various scholarships, providing up to $3,000 in financial assistance. This initiative encourages women to further their education while addressing the unique needs of the community.

About The Community Foundation

The Community Foundation of Herkimer and Oneida Counties is a community-based social impact investor whose mission is to engage, invest, and lead—working toward a vision of community vibrancy with opportunity for all. Our team of experienced staff and dedicated trustees is committed to boldly leading and supporting transformational community investments. We channel charitable contributions from donors through nonprofit partners that are meeting current community needs and steward community resources responsibly to ensure greater capacity for the future.

Adirondack League Club Scholarship

Established by Adirondack League Club to award scholarships to students in the Central Adirondack region of the Adirondack Park.

Candidates are identified by a committee.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a graduating high school senior who is a current employee of a McDonald’s restaurant located in Northeastern Pennsylvania.

The Community Foundation of Marquette County distributes over $130,000 annually in scholarships to benefit aspiring students in Marquette County.

The Paul W. and Pearl K. Goodman Music Scholarship Fund

Provides financial assistance for individuals attending the NICE School District (grades 3 to 10, based on financial need) to take part in instrumental and vocal music lessons.

Distribution Process

• CFMC scholarship recipients will be contacted in June requesting student enrollment verification
• Scholarships can only be distributed once student’s information is received
• Scholarships will be distributed to the college/school/university indicated by student
• The scholarship must be used for tuition and fees required for the enrollment or attendance of the student at a qualifying educational institution; fees, books, supplies, and equipment required for courses of instruction at such an educational institution; and room and board, within the first semester of first year of students enrollment
• That year’s recipient must claim the scholarship within that fiscal year to be distributed (by 12/31/xx)

The Community Foundation of Marquette County distributes over $130,000 annually in scholarships to benefit aspiring students in Marquette County. 

Saint Paul’s School Commemorative Fund

Provides financial assistance to members of St. Paul’s Parish who will be pursuing certification or a degree at an institution of higher education. 

Distribution Process

• CFMC scholarship recipients will be contacted in June requesting student enrollment verification
• Scholarships can only be distributed once student’s information is received
• Scholarships will be distributed to the college/school/university indicated by student
• The scholarship must be used for tuition and fees required for the enrollment or attendance of the student at a qualifying educational institution; fees, books, supplies, and equipment required for courses of instruction at such an educational institution; and room and board, within the first semester of first year of students enrollment
• That year’s recipient must claim the scholarship within that fiscal year to be distributed (by 12/31/xx)

The Spotlight Funds: Inclusive Classroom Grants support K-12 educators by providing financial assistance to acquire essential tools and materials for diverse classrooms. These grants address inequities based on race, gender identity, and ability, ensuring that all students have the resources they need to succeed. With awards ranging from $500 to $1,000 per educator, the program prioritizes high-needs schools, empowering teachers to create inclusive learning environments that reflect their students' unique backgrounds.

Indian Health Service

The Indian Health Service, an agency within the Department of Health and Human Services , is responsible for providing federal health services to American Indians and Alaska Natives. The provision of health services to members of federally-recognized tribes grew out of the special government-to-government relationship between the federal government and Indian tribes. This relationship, established in 1787, is based on Article I, Section 8 of the Constitution, and has been given form and substance by numerous treaties, laws, Supreme Court decisions, and Executive Orders. The IHS is the principal federal health care provider and health advocate for Indian people, and its goal is to raise their health status to the highest possible level. The IHS provides a comprehensive health service.

IHS Extern Program

Become an IHS Extern

The Indian Health Service (IHS) offers IHS scholarship recipients and other qualified students the opportunity to participate in a hands-on instructive experience that will complement the knowledge and skills developed in school. This experience will help to enhance pre-professional training, while also familiarizing yourself with Native communities that are of interest to you when you begin your health professions career.

IHS externs are employed for 30 to 120 workdays per calendar year during non-academic periods

Salary

Externs received a salary based on experience and years of academic training that is comparable to industry standards. IHS will waive your salary if the externship fulfills a required academic field placement or an internship.

Housing

Externs are responsible for securing their own housing arrangements. Host sites may be able to provide information or resources to assist in identifying housing options within the community. Externs are encouraged to maintain communication with their Extern Coordinator and host site to ensure all arrangements are confirmed prior to travel. This preparation supports a smooth transition into the externship experience and enables externs to focus on contributing to the Indian Health.

Eligible degree programs for Summer 2025 (must be accepted into program at time of application):

• Pre-Nursing (Sophomore Level, leading to a Bachelor Degree of Science)
• Pre- Medicine (Junior/Senior Level, leading to a Bachelor Degree of Science)
• Pre-Dentistry (Junior/Senior Level, leading to a Bachelor Degree of Science)

Must be enrolled in the Bachelor Degree program by January 1, 2025:

• Nursing
• Environmental Health
• Engineering (Civil or Environmental - Accreditation Board for Engineering and Technology)
• Clinical Laboratory Scientist
• Dental Hygiene
• Diagnostic Radiology

Must be enrolled in the Master Degree program by January 1, 2025:

• Nurse Midwife
• Social Work (LCSW)
• Nurse Practitioner
• Physician Assistant
• Occupational Therapy

Must be enrolled in the Doctoral Degree program by January 1, 2025:

• Clinical Psychology
• Dentistry
• Nurse Anesthetist
• Nurse Practitioner (DNP)
• Optometry
• Pharmacy
• Physician, Allopathy
• Physician, Osteopathy
• Physical Therapy
• Podiatry

Duties include:

• Gain working knowledge and experience in your chosen health profession or field with Indian Health Service during non-academic periods for up to 120 workdays per calendar year.
• Assist preceptor in daily duties in their academic field.
• Assist and prepare reports on assigned projects.
• Assist on day-to-day administrative operations by performing tasks related to their department functions.

The HEAL Initiative's new program aims to generate comprehensive datasets on human pain networks through advanced 'omics and physiology research. Utilizing primary human tissues, the initiative promotes collaboration among diverse experts to enhance the understanding of pain mechanisms. This cooperative agreement will foster best practices and data sharing, ensuring integrated approaches across various pain conditions. While applications are not currently being accepted, the initiative encourages multidisciplinary teams to prepare for future opportunities in pain research.

The HEAL Initiative Whole Joint Health Program aims to advance research on the biological mechanisms of joint pain by exploring the interactions of various tissues within the joint. This innovative program will support clinical studies that focus on non-pharmacological interventions to enhance healing and improve quality of life for individuals suffering from chronic joint pain. By fostering a comprehensive understanding of joint health, the initiative aligns with the NIH's broader goals to reduce chronic pain and opioid dependency.

The GSK Research Grant supports research on Social Determinants of Health (SDOH) and Diversity/Equity/Inclusion (DEI) in Otolaryngology. With funding of $25,000 for one year, it encourages projects that explore the intersection of patient care and workforce culture. Investigators are invited to address disparities in care, diagnosis, and treatment paradigms while enhancing understanding of these critical dimensions in healthcare. Applications must include letters of support from department chairs and co-investigators.

The Innovative Programs to Enhance Research Training (IPERT) initiative by the NIH aims to support innovative educational activities that enhance the skills of participants across various career stages in the biomedical research field. This program focuses on courses for skills development, mentoring activities, and curriculum or methods development, ensuring a robust structure for leadership, recruitment, and evaluation.

The Emerging Respiratory Pathogen Award, offered by the American Lung Association, aims to enhance our understanding of respiratory infections' pathobiology and their implications. This award supports innovative research addressing the biology of respiratory viruses, host response factors, community spread dynamics of COVID-19, and long-term effects of viral infections. With a funding of $100,000 per year for two years, this initiative encourages groundbreaking studies to improve lung health and disease outcomes.

The Community Foundation of Marquette County distributes over $130,000 annually in scholarships to benefit aspiring students in Marquette County.

Father Vincent L. Ouellette Scholarship Endowment Fund

Provides financial assistance for graduating high school students who are members of the St. Joseph’s Parish and will be pursuing a degree at a four year college or university. 

Distribution Process

• CFMC scholarship recipients will be contacted in June requesting student enrollment verification
• Scholarships can only be distributed once student’s information is received
• Scholarships will be distributed to the college/school/university indicated by student
• The scholarship must be used for tuition and fees required for the enrollment or attendance of the student at a qualifying educational institution; fees, books, supplies, and equipment required for courses of instruction at such an educational institution; and room and board, within the first semester of first year of students enrollment
• That year’s recipient must claim the scholarship within that fiscal year to be distributed (by 12/31/xx)

The Community Foundation of Marquette County distributes over $130,000 annually in scholarships to benefit aspiring students in Marquette County.

Bernadette Reider Scholarship Fund

Provides scholarships to students from Marquette County who are entering into a college educational program in the field of nursing. Applicants will also be judged by financial need.

Distribution Process

• CFMC scholarship recipients will be contacted in June requesting student enrollment verification
• Scholarships can only be distributed once student’s information is received
• Scholarships will be distributed to the college/school/university indicated by student
• The scholarship must be used for tuition and fees required for the enrollment or attendance of the student at a qualifying educational institution; fees, books, supplies, and equipment required for courses of instruction at such an educational institution; and room and board, within the first semester of first year of students enrollment
• That year’s recipient must claim the scholarship within that fiscal year to be distributed (by 12/31/xx)

The HEAL Initiative aims to develop non-addictive therapeutics for pain management through small molecules and biologics. This funding opportunity supports preclinical optimization, facilitating the transition of promising candidates to clinical trials. Important proposal deadlines span from January 2024 to January 2027, with optional Letters of Intent encouraged 30 days prior. The program emphasizes collaboration with NIH staff to ensure thorough project planning and monitoring, aiming to revolutionize pain treatment while ensuring safety and efficacy.

The Juliette M. Atherton Scholarships support Protestant ministers pursuing advanced theological education in the U.S., particularly those who have completed a seminary degree. Applicants must be ordained ministers, residents of Hawai’i, and maintain a minimum GPA of 2.0. Funding is available for up to four years, requiring annual reapplication. This scholarship aims to enhance educational opportunities for ministers committed to their faith and community.

The National Cancer Institute invites applications for the validation of biomarkers and assays for cancer detection and treatment. This funding opportunity supports both analytical and clinical validation of assays, emphasizing the importance of human samples. The program encourages multi-disciplinary collaboration and aims to enhance the performance and reproducibility of cancer assays across clinical laboratories. Applications are due by 5:00 PM local time during the designated deadlines each year.

The ASRM/PSF Combined Pilot Research Grant, funded by the Plastic Surgery Foundation, aims to support innovative research in reconstructive microsurgery. By providing up to $10,000 for 1-year pilot projects, this grant encourages the development of surgeon scientists and promotes the advancement of scientific knowledge and clinical practices in the field. The initiative fosters collaboration among key organizations dedicated to enhancing research funding for impactful studies.

The Combined Pilot Research Grants from the Plastic Surgery Foundation and the American Society of Maxillofacial Surgeons aim to promote innovative research in maxillofacial surgery. With funding of up to $15,000 for one-year pilot projects, this initiative supports the preliminary phases of research, fostering the development of surgeon scientists and enhancing scientific knowledge in the field. Eligible applicants include MDs, DOs, or PhDs holding full-time positions in U.S. or Canadian institutions.

The Combined Pilot Research Grants by the AAPPS and PSF aim to promote innovative research in pediatric plastic surgery and hand surgery. With funding up to $15,000 for one-year pilot projects, these grants support the development of surgeon scientists and encourage applications that will enhance the scientific understanding and improve care for children with deformities requiring reconstructive surgery. This initiative fosters collaboration among various subspecialty organizations dedicated to advancing surgical research.