Best Large Grants for Nonprofit Organizations in South Carolina

The National Centers for Biomedical Imaging and Bioengineering (NCBIB) provide critical resources for biomedical imaging and bioengineering research. This funding opportunity supports the development of innovative technologies tailored to the needs of basic, translational, and clinical researchers. NCBIB facilitates technology access, training, and dissemination, enhancing collaboration and advancing the field. Applications are encouraged to foster advancements that address complex biomedical challenges.

Community Foundation of Henderson County

Community Foundation of Henderson County was incorporated in 1982 by a group of fourteen dedicated and compassionate local leaders with the immediate need to manage two funds - the William C. Armstrong Scholarship Fund and the Charlie Renfrow Scholarship Fund, in addition to providing a permanent vehicle for citizens to give back to their community.

Our Mission is to help people who care make lasting contributions to causes that matter. The Community Foundation of Henderson County is a highly visible, philanthropic leader directed by an engaged and committed board, staffed by qualified employees, empowering donors at all levels to invest in professionally managed charitable funds that address community needs.

Maude and Harvey Goehring Scholarship

This scholarship is for a student preparing to teach physical science or mathematics in the public secondary schools. The recipient shall be a citizen and resident of Henderson County and shall have graduated from a Henderson County high school. The recipient shall be required to need financial assistance to pursue his or her education at a post-high school institution.

About Community Foundation of Henderson County

• Mission: Helping people who care make lasting contributions to causes that matter.
• Vision: Community Foundation of Henderson County is a highly visible, philanthropic leader directed by an engaged and committed board, staffed by qualified employees, empowering donors at all levels to invest in professionally managed charitable funds that address community needs.

Haddy Harrington Memorial Scholarship

This scholarship is to provide financial assistance for students who have demonstrated a passionate desire for advanced education in art or writing. Applicant must be a graduate of a Henderson County high school with a minimum 3.0 GPA.

This is a renewable scholarship.

The Readiness and Recreation Initiative (RARI) by the National Park Service aims to enhance outdoor recreation and support compatible land uses near military installations. This program, funded through the Land and Water Conservation Fund, provides up to 50% of project costs, encouraging collaboration with the Department of War. Projects must involve land acquisition and align with national priorities to ensure public outdoor access in perpetuity, directly benefiting both military and civilian communities.

The ACES Foundation Fund, managed by The Foundation for Enhancing Communities, offers scholarships to high school seniors from Cumberland, Dauphin, or Perry County. Eligible students must pursue business-related studies or trades, demonstrate academic achievement with a minimum GPA of 2.5, and show commitment to community service. This initiative aims to support future entrepreneurs and enhance community development through educational funding.

The Conrad Siegel “Numbers Matter” Community Scholarship Fund, established by Conrad M. Siegel, Inc., supports underserved students in Central PA pursuing degrees in math, finance, and related fields. This initiative aims to enhance diversity in financial professions by alleviating the financial burden of higher education for students from minority backgrounds. The Foundation for Enhancing Communities, dedicated to strengthening local communities, manages this scholarship to empower the next generation of leaders in these disciplines.

The Harry N. and Melva A. Derickson Scholarship, managed by The Foundation for Enhancing Communities, supports residents of Cumberland, Dauphin, and Perry Counties pursuing degrees in medical, dental, nursing, physical therapy, or engineering fields. This endowment aims to promote academic achievement and community service, with a preference for gender balance in award distribution. By investing in future healthcare professionals, the scholarship fosters educational advancement and strengthens local communities.

The Jack and Edna May Yost Scholarship, managed by The Foundation for Enhancing Communities, supports graduating seniors from Dauphin or Cumberland counties pursuing higher education at accredited colleges. Priority is given to children of postal employees and those majoring in nursing or education. Applicants must have a minimum GPA of 2.5, demonstrate community service, and show financial need. This scholarship aims to empower students and promote educational equity in the community.

The NASN Research Grants, established by the National Association of School Nurses, aim to promote research on school nursing and the health of school-aged children. These grants support innovative projects led by school nurses who are NASN members. The program emphasizes the importance of quality school nursing practice, encouraging applications that adhere to specified guidelines and focus on future research initiatives. With a rich history of funding impactful studies, NASN continues to advance healthcare delivery in educational settings.

Sam A. Mills Memorial Scholarship

Applicant must be a graduate of a Henderson County public high school who is pursuing an undergraduate degree in an accredited school on a full-time basis. The applicant must demonstrate financial need and show scholastic achievement and good citizenship.

Amount

• $1000

The Nathan Cummings Foundation offers Venture Grants to support social entrepreneurs with innovative solutions addressing inequality and climate change. These short-term grants aim to foster partnerships and expedite necessary funding. The foundation prioritizes projects aligned with its mission of advancing racial, economic, and environmental justice, focusing on systemic change through a holistic approach. Eligible applicants must demonstrate alignment with the foundation's values of diversity, equity, and inclusion to qualify for funding opportunities.

The VFW is dedicated to promoting patriotism and investing in our future generation. If you are a democracy-loving high school student interested in a $35,000 college scholarship or a patriotic middle school student interested in winning $5,000, these scholarships may be for you.

VFW Youth Scholarships- Voice of Democracy

Established in 1947, our Voice of Democracy® audio-essay program provides high school students with the unique opportunity to express themselves in regards to a democratic and patriotic-themed recorded essay. Each year, nearly 28,000 ninth through 12th grade students from across the country enter to win their share of more than $1.6 million in educational scholarships and incentives awarded through the program. 

The national first place winner receives a $35,000 scholarship paid directly to the recipient’s American university, college or vocational/technical school. The complete list of other national scholarships range up to $21,000, with the first place winner from each VFW Department (state) winning a scholarship of at least $1,000.

VFW Department (state) first place winners also receive a trip to participate in Founding Forward’s Spirit of America Youth Leadership experience at Valley Forge which is an inspiring four-day program where students experience mock congressional debates, participate in a free enterprise challenge, visit historical sites and engage in interactive educational activities. This immersive experience allows students to develop their critical thinking and leadership skills while understanding their responsibilities as citizens. The trip, awarded to every VFW Department (state) winner, is made possible through the generous support of Twisted X.

Students interested in participating must submit their audio essay prepared on this year's theme, with a completed entry form to their local participating VFW Post. 

The Andy Warhol Foundation's Arts Writers Grant supports writers engaging with contemporary visual art through various formats, including articles, books, and short-form writing. Grants range from $15,000 to $50,000, catering to both emerging and established writers. Eligible applicants must be individuals over 25, U.S. citizens or residents, and published authors. This initiative encourages critical discourse and interdisciplinary approaches in arts writing, particularly related to post-World War II visual art and its diverse contexts.

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

Washington Goes Purple Scholarship

This scholarship is open to students that reside in Washington County, MD, are continuing their education, and have been affected by substance use.

The H. Lyman Mooney Music Scholarship, offered by the Community Foundation of the Ozarks, provides a $450 scholarship to a graduating senior from Marshfield High School pursuing music studies. Applicants must submit their transcripts, demonstrate financial need through FAFSA-SAI, and provide a letter of recommendation from their music teacher. The scholarship application period will reopen on January 1, 2026, for the 2026–27 academic year, aiming to support students in achieving their educational goals.

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

Washington County Hospital School of Nursing Alumni Scholarship

Founded by alumni of Washington County Hospital’s School of Nursing, this fund serves to provide scholarships to deserving students who are continuing their education in Nursing.

The MG Eugene C. Renzi, USA (Ret.) STEM Teachers Scholarship, funded by AFCEA and ManTech International, offers $2,500 annually to support U.S. citizens or permanent residents pursuing graduate-level education in STEM teaching for grades K-12. This scholarship honors the legacy of Maj. Gen. Renzi and is aimed at candidates with a minimum GPA of 3.5 who are enrolled in accredited programs. It covers tuition and course-related expenses, fostering future educators in critical STEM fields.

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Pi-Squared Scholarship

Benefiting graduating seniors of Spring ISD (Texas), Klein ISD (Texas), and Houston ISD (Texas).

The Bill Cox Memorial Scholarship offers a $1,750 award to graduating seniors from Spokane High School, aimed at supporting their educational aspirations. Applicants must maintain a GPA of 2.5 or higher, demonstrate financial need through FAFSA-SAI, and submit a transcript along with an essay detailing community service and school activities. A letter of recommendation is also required. The scholarship application period will reopen on January 1, 2026 for the 2026–27 academic year.

The ACUMEN Scholarship, provided by the East Bay Community Foundation, aims to support financially challenged students from Youth Spirit Artworks, Oakland Tech High School, and McClymonds High School. Each year, up to three scholarships are awarded, with amounts of $5,000 for 2-year colleges and $8,000 for 4-year colleges. This initiative is designed to assist students with educational costs, encouraging their commitment to higher education.

The Elevance Health Foundation's Behavioral Health Grant aims to address significant challenges in mental health and substance use disorders. With a commitment of up to $90 million over three years, the Foundation seeks partnerships with nonprofits to enhance treatment access, promote prevention strategies, and alleviate loneliness among affected individuals. This initiative emphasizes innovative solutions and measurable outcomes, targeting both national and local programs, particularly in states with pressing health disparities.

Thomas D. Buckley Trust

Thomas Dennis Buckley was born in December 1897 in Missouri to Dennis and Susan Buckley. His family—his parents, brothers Frank and John, sister Elizabeth, and Tom—moved to Lamar in 1906. In 1917, Tom came to Chappell, Nebraska with his brothers. The men lived in a bunkhouse on wheels and hired out to break sod using a one-cylinder Rumley tractor. After serving one year in the military, Tom worked on the railroad for several years before returning to Chappell, where he began farming. He continued farming until his death on June 12, 1979.

Upon his death, a Private Foundation—the Thomas D. Buckley Trust—was formed in accordance with his wishes. The Trustees sold his land in 1980 at record-high prices and invested the proceeds, along with the investments Tom held at the time of his death. These funds continue to support the mission of the Trust today.

Thomas D. Buckley Trust Continuing Education Scholarship

The Trust awards $20,000 of scholarships to students who are currently enrolled in college seeking Associate Degrees or Bachelor Degrees. There will be ten $2,000 scholarships awarded each year to students who will be a college Sophomore, Junior, or Senior during the next Fall Semester.

Each scholarship will be paid $1,000 in the Fall Semester and $1,000 in the Spring Semester, and cannot be carried to another year. The payments will be sent directly to the school that the recipient is attending.

The scholarship money can be used for tuition, room and board, fees and books.

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Roger and Barbara Powell Scholarship for Nursing

Benefiting rural Texas residents pursuing nursing degrees.

The TFEC Aspire to Rise Scholarship Fund, managed by The Foundation for Enhancing Communities, offers financial support to non-traditional students aged 22 and older who have faced challenges in their educational journey. This scholarship is aimed at those pursuing higher education or vocational training, with special consideration for applicants without a post-secondary degree. Additionally, it supports individuals preparing for the GED, fostering opportunities for personal and professional growth in South Central Pennsylvania.

The TFEC Student Emergency Assistance Fund provides crucial financial support for students facing unexpected hardships that threaten their continuation in post-secondary education. Grants of up to $500 per application are available, with a total funding limit of $1,500 for re-applications. This initiative is part of The Foundation for Enhancing Communities' mission to bolster local educational opportunities and foster community resilience, ensuring that students can overcome financial barriers and achieve their academic goals.

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Strong Family Scholarship

Benefiting graduating high school seniors from charter schools in Houston, TX.

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Tradition of Excellence Scholarship

Benefiting dependents of current Perry Homes employees.