Best Large Grants for Nonprofit Organizations in South Carolina

The Alice and William Johnson Foundation Scholarship is managed by the Northern Piedmont Community Foundation, aimed at supporting graduating seniors from Fauquier County public high schools. This scholarship, which values education and community commitment, provides $5,000 annually for four-year universities and $2,500 for two-year schools, with renewal options available. Priority is given to students demonstrating financial need, ensuring that financial barriers do not hinder their educational aspirations.

The Rodgers Family Agricultural Scholarship, managed by the Northern Piedmont Community Foundation, supports graduating seniors from Fauquier County pursuing degrees in agricultural fields at accredited institutions. Candidates must demonstrate financial need, initiative, motivation, and leadership. This scholarship not only offers financial assistance but also presents opportunities for renewal, fostering academic growth and community involvement among students dedicated to agriculture in the region.

YWCA Chester County Fund

Mission Statement

A primary focus of the YWCA Chester County Fund is to provide scholarships to women, primarily non-traditional students, to continue their education.

CRST Wicozani Wiwokiaye Oyate Scholarship for Nursing

To provide financial support to Native American students pursuing a registered nursing degree.

For a Cheyenne River Sioux Tribe (CRST) member aiming to earn a nursing degree, if there are no eligible CRST candidates, the scholarship will be accessible to another tribal member. Proof of tribal enrollment is required for both applicants. This scholarship is available to students in their second through fifth years who have sustained a GPA of 2.0 or above. When applying for this scholarship, articulate how your nursing education will contribute to enhancing the health outcomes of Native American communities.

(Pronunciation is: Wee-Cho-Zan-Ee, Wee-Woke-Ee-Eye-Aye, Oh-Yah-Tay. Which is Lakota for "Health Helpers Society")

This funding opportunity invites applications for investigator-initiated clinical trials focused on complementary and integrative health interventions delivered remotely or via mobile health technologies. The trials must be fully powered, with no in-person contact, and require justification for this approach. Preliminary data on feasibility and safety must be provided, alongside evidence of clinical benefit. A Plan for Enhancing Diverse Perspectives is mandatory for submission. Key deadlines range from February 2024 to June 2026.

The Elizabeth Nash Foundation Scholarship supports individuals affected by cystic fibrosis (CF) in their pursuit of higher education. Since its inception in 2005, over 200 scholarships ranging from $1,000 to $2,500 have been awarded to undergraduates and graduates at accredited U.S. institutions. The selection process considers academic performance, character, leadership, community service, and financial need. To qualify, applicants must have a CF diagnosis and be U.S. citizens.

The Colonel David Marcus Memorial Scholarship Award supports students from Burlington, Camden, or Gloucester Counties pursuing post-high school education, particularly in military programs. Established by the Jewish Community Foundation, this scholarship prioritizes candidates who embody Col. Marcus's ideals. Eligible applicants must be high school seniors and may apply for multiple awards. The fund has a strong community leadership background, managing over $35 million in assets to support educational initiatives.

The National Institute of Neurological Disorders and Stroke (NINDS) is launching a collaborative initiative aimed at exploring neurodegenerative mechanisms in Alzheimer’s disease-related dementias (ADRD). This program, termed 'Centers without Walls', encourages interdisciplinary teams to merge diverse expertise, utilizing cutting-edge technologies and clinical insights to uncover novel ADRD pathways. By fostering collaboration and data sharing, the initiative seeks to enhance understanding of ADRD complexities and support the development of innovative therapeutic strategies.

The Conagra Brands Foundation offers Community Impact Grants to nonprofit organizations in the USA that address food insecurity and promote healthy lifestyles. Eligible organizations must align with core focus areas like food access, nutrition education, and cooking skills. Grants support initiatives that foster community engagement and provide entrepreneurial skills. Nonprofits must uphold a non-discrimination policy protecting various characteristics. Applications are accepted through a Letter of Intent from January 1 to February 15, 2025.

The Book Buddies Program, initiated by The Molina Foundation, aims to combat the lack of access to books in low-income communities. By distributing new, free books to eligible schools and agencies, the program fosters literacy and learning among children. With over 4 million books distributed, it helps create word-rich environments essential for educational success. This initiative supports families in building home libraries and enhances learning spaces, ensuring children have the resources they need to thrive.

This RFP invites proposals that explore the role of maintenance therapy in HER2+ metastatic breast cancer. It aims to enhance understanding of treatment optimization, emphasizing patient quality of life and individualized treatment strategies. Eligible applicants include organizations from the U.S. and select European countries. The focus is on educational projects that improve awareness among healthcare professionals, with a range of formats accepted, including live sessions and online content. Clinical research projects are excluded.

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Response & Emergency Needs Fund

The NAFC Response & Emergency Needs Fund is designed to address urgent and unforeseen challenges that threaten operations or patient access to care within NAFC member organizations. These organizations often operate with limited reserves, making them especially vulnerable to unexpected repairs, equipment failures, workforce disruptions, or community emergencies. This fund provides rapid, flexible support to help stabilize operations and ensure continuity of care for uninsured and underserved patients.

The Carolyn Gallmeyer Scholarship, provided by the Grand Rapids Community Foundation, supports students from Kent County pursuing college or career training. This scholarship aims to remove barriers to education, empowering students to achieve their aspirations. With awards typically ranging from $2,000 to $5,000, it directly contributes to tuition and essential costs. The foundation emphasizes inclusivity, ensuring that all students have the opportunity to thrive in their academic journeys.

Grand Rapids Community Foundation

Connecting people, passion and resources

The Community Foundation is a nonprofit organization that connects people, passion and resources. With our partners, the Community Foundation uses the tools of philanthropy to find solutions to pressing issues. We provide grants to support the work of nonprofits, scholarships to local students and other forms of support to communities working to eliminate barriers to opportunity, prosperity and belonging.

Our Mission is to build and manage our community’s permanent endowment and lead the community to strengthen the lives of its people.

We envision a magnetic and interconnected West Michigan community.

Integrity, Excellence, Inclusion, Sustainability and Bold Aspirations

Give and Receive Openly, Build Trust with Each Other, Create Brave and Safe Space, Embrace Vulnerability, Accountability

Our North Star

For West Michigan to grow and prosper, we must make sure that everyone can apply their talents and creativity to fuel our future. It is only by connecting across perspectives and overcoming inequities that we can build and sustain an inclusive economy and thriving community.

Opportunities for students

Apply for scholarships to support your ambitions

Each year Grand Rapids Community Foundation supports hundreds of students on their college or career training journeys. We are excited to remove barriers to academic success so that students like you can pursue what you're passionate about.

Scholarship Fund Details

Support for West Michigan Students

Attending college or trade school increases opportunity and opens doors to careers. Donor partners who establish a scholarship fund give students a boost on their path to higher education. Students who complete the general scholarship application are considered for these scholarships.

Open to students who are residents of Kent County. Preference to Challenge Scholar students through 2032.

Grand Rapids Community Foundation

Connecting people, passion and resources

The Community Foundation is a nonprofit organization that connects people, passion and resources. With our partners, the Community Foundation uses the tools of philanthropy to find solutions to pressing issues. We provide grants to support the work of nonprofits, scholarships to local students and other forms of support to communities working to eliminate barriers to opportunity, prosperity and belonging.

Our Mission is to build and manage our community’s permanent endowment and lead the community to strengthen the lives of its people.

We envision a magnetic and interconnected West Michigan community.

Integrity, Excellence, Inclusion, Sustainability and Bold Aspirations

Give and Receive Openly, Build Trust with Each Other, Create Brave and Safe Space, Embrace Vulnerability, Accountability

Our North Star

For West Michigan to grow and prosper, we must make sure that everyone can apply their talents and creativity to fuel our future. It is only by connecting across perspectives and overcoming inequities that we can build and sustain an inclusive economy and thriving community.

Opportunities for students

Apply for scholarships to support your ambitions

Each year Grand Rapids Community Foundation supports hundreds of students on their college or career training journeys. We are excited to remove barriers to academic success so that students like you can pursue what you're passionate about.

Scholarship Fund Details

Support for West Michigan Students

Attending college or trade school increases opportunity and opens doors to careers. Donor partners who establish a scholarship fund give students a boost on their path to higher education. Students who complete the general scholarship application are considered for these scholarships.

Open to students who are residents of Kent County. Preference to Challenge Scholar students through 2032.

The Home Depot Foundation's Veteran Housing Grants Program aims to enhance the lives of U.S. veterans by funding the construction or rehabilitation of supportive housing. Grants, ranging from $100,000 to $500,000, are awarded to 501(c)(3) nonprofit organizations with experience in veteran housing. Since 2011, the Foundation has committed over $550 million to veteran causes and seeks to invest an additional $750 million by 2030, focusing on projects in major cities across the U.S.

Grand Rapids Community Foundation

Connecting people, passion and resources

The Community Foundation is a nonprofit organization that connects people, passion and resources. With our partners, the Community Foundation uses the tools of philanthropy to find solutions to pressing issues. We provide grants to support the work of nonprofits, scholarships to local students and other forms of support to communities working to eliminate barriers to opportunity, prosperity and belonging.

Our Mission is to build and manage our community’s permanent endowment and lead the community to strengthen the lives of its people.

We envision a magnetic and interconnected West Michigan community.

Integrity, Excellence, Inclusion, Sustainability and Bold Aspirations

Give and Receive Openly, Build Trust with Each Other, Create Brave and Safe Space, Embrace Vulnerability, Accountability

Our North Star

For West Michigan to grow and prosper, we must make sure that everyone can apply their talents and creativity to fuel our future. It is only by connecting across perspectives and overcoming inequities that we can build and sustain an inclusive economy and thriving community.

Opportunities for students

Apply for scholarships to support your ambitions

Each year Grand Rapids Community Foundation supports hundreds of students on their college or career training journeys. We are excited to remove barriers to academic success so that students like you can pursue what you're passionate about.

Scholarship Fund Details

Support for West Michigan Students

Attending college or trade school increases opportunity and opens doors to careers. Donor partners who establish a scholarship fund give students a boost on their path to higher education. Students who complete the general scholarship application are considered for these scholarships.

Open to students who are residents of Kent County. Preference to Challenge Scholar students through 2032.

The National Institute on Aging (NIA) is set to release a Notice of Funding Opportunity (NOFO) aiming to stimulate research on Alzheimer's disease (AD) and related dementias (ADRD). This initiative focuses on validating novel drug targets and supports early-stage drug discovery efforts. The U01 activity code will be utilized, and while applications are not currently solicited, this notice allows potential applicants ample time to form collaborations and develop impactful projects in the field of AD/ADRD research.

Mission Statement

Beckley Area Foundation exists to inspire and facilitate generous charitable giving that advances our community.

The Beckley Area Foundation is committed to enriching lives and strengthening communities across Southern West Virginia.

Scholarship

Supporting Student Success

The Beckley Area Foundation proudly manages scholarship funds established by individuals, businesses, and organizations dedicated to helping students pursue higher education. Many of these scholarships are tailored for specific schools, fields of study, or graduates from local high schools, while others offer broader opportunities. No matter the path, our scholarships aim to support students from our region as they work toward achieving their educational goals.

Donaghue Nursing Scholarship

Eligibility

One or more scholarships for Raleigh Co. high schools graduates who have achieved a satisfactory academic record and are pursuing a nursing career; Financial need shall be considered in selection.

Mission Statement

Beckley Area Foundation exists to inspire and facilitate generous charitable giving that advances our community.

The Beckley Area Foundation is committed to enriching lives and strengthening communities across Southern West Virginia.

Scholarship

Supporting Student Success

The Beckley Area Foundation proudly manages scholarship funds established by individuals, businesses, and organizations dedicated to helping students pursue higher education. Many of these scholarships are tailored for specific schools, fields of study, or graduates from local high schools, while others offer broader opportunities. No matter the path, our scholarships aim to support students from our region as they work toward achieving their educational goals.

The Christie H. Meadows Family Scholarship

Eligibility

Need based scholarship for Raleigh County graduates, Member of FFA (Future Farmers of America) and/or 4Hclub, Required documentation of participation in FFA and/or 4H club, and preference given to students who have submitted an FFA and/or 4H project to the West Virginia State Fair.

The Get Out and Get Active Grant by the Anxiety & Depression Initiative supports innovative projects that promote the mental health benefits of physical activity. This funding aims to reduce anxiety and depression through community fitness programs and educational campaigns, emphasizing the intersection of physical activity and mental health. Eligible applicants include nonprofits and academic institutions in the U.S. seeking to enhance well-being and integrate active lifestyles for individuals living with mental illness.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

Established in January 2026, the Irene Zurine Memorial Scholarship Fund awards scholarships each year to support girls and women, traditional or nontraditional students, who are furthering their education.

The McKnight Brain Research Foundation Innovator Awards aim to support innovative research in cognitive aging and memory loss, offering two 3-year grants of $750,000 each. Targeted at early-career investigators, the program encourages high-risk, high-gain proposals that explore clinical translational research and the biological mechanisms of cognitive aging. By fostering emerging scientific leaders, the initiative seeks to advance transformative discoveries in this critical area of aging research, enhancing understanding and treatment of age-related cognitive decline.

The Scottie W. Cox Memorial Scholarship of NCCCLA supports employees of learning resources centers in North Carolina pursuing advanced degrees in library and information studies. Eligible applicants must have at least a bachelor's degree and be enrolled in accredited programs. This scholarship, administered by the North Carolina Community Foundation, opens for applications on December 16, 2025, and closes on March 3, 2026. It aims to enhance professional development in the library sector.

The ROSS Rapid Response Program (RRP) by the U.S. Department of Housing and Urban Development (HUD) provides expedited funding to assist communities in addressing urgent social needs. This program offers one-time cost-reimbursable grants for service coordination and direct services, especially in response to emergencies like natural disasters or public health crises. By streamlining the application process, the RRP empowers local leaders to efficiently support residents in HUD-assisted housing, promoting self-sufficiency and resilience.

The Abbvie Parkinson’s Disease Grant aims to enhance the understanding and management of subcutaneous infusion therapies for advanced Parkinson’s disease. As these therapies become more prevalent, it is crucial for Movement Disorder Specialists and General Neurologists to develop confidence in identifying, mitigating, and managing infusion site events. This grant seeks to provide essential education and resources to support safe and effective treatment options for patients experiencing motor fluctuations.

L’Oréal Paris Celebrates 20 Years of Women of Worth

For 20 years, L’Oréal Paris has honored women who uplift their communities through service. These non-profit leaders, our Women of Worth, each receive $25,000 to support their causes, mentorship from the L’Oréal Paris network and a national platform to share their stories.