Best Private Grants for Nonprofits in South Carolina

The Emily Hall Tremaine Exhibition Research Grant supports innovative projects that explore contemporary art in new frameworks. With a focus on education in the United States, the foundation emphasizes the importance of research that challenges conventional thought. Grants of $10,000 are awarded to curators collaborating with established non-profits, promoting impactful exhibitions. The foundation aims to foster family unity and respect while addressing enduring societal issues through art, environment, and learning differences.

The Never Lose Hoop Fund, established by JC and Joni Hulls, provides grants to support families affected by cancer. The fund aims to enhance the quality of life for children and their families through shared experiences, such as family camps and outdoor activities. Grants are available for those currently battling cancer or who have lost an immediate family member to cancer within the last two years. This initiative helps families create lasting memories and find joy during difficult times.

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

Music Scholarship

At a very early age in Alabama, Lee Essie Smith was a self-taught musician. After losing her mother as a young teenager, she began putting her God-given musical talent to work as a pianist for several churches. By the time she graduated from high school, she had learned the cosmetology trade and met Charlie McMillan, Jr.

After his wife’s death, Mr. McMillan continued his community service with the Democratic Party, Habitat for Humanity and Mt. Olive Baptist Church as an usher. Although he did not serve very long in the military, Mr. McMillan continues to exemplify the values and physical energy of the “Army Strong” slogan. He is the patriarch of the family – always dapper – and a regular attendee at church services.

The Arthritis National Research Foundation (ANRF) offers grants for research focused on Psoriatic Arthritis (PsA). With funding of up to $125,000 over two years, the ANRF encourages innovative projects that reveal the underlying mechanisms of PsA. Eligibility includes M.D. or Ph.D. qualifications and affiliation with a U.S. nonprofit research institution. Preference is given to senior post-doctoral researchers transitioning to independent status and new assistant professors. Applications without a Co-PI or those who have previously received ANRF funding will not be accepted.

The 1Fur1 Foundation Grant supports U.S.-based 501(c)(3) charities that engage in animal-assisted programs. Eligible organizations can apply for grants ranging from $500 to $7,500 to support Animal Assisted Therapy, Activity, and Service Dog programs. The foundation focuses on charities that align with its mission and does not fund individual requests, for-profit businesses, or initiatives that promote animal cruelty. Applications are reviewed within 90 days.

The Greater Tindall Neighborhood Scholarship Fund, established by the Community Foundation of Central Georgia, aims to support residents of Tindall Heights pursuing post-secondary education. It offers $2,000 per recipient, renewable for up to four years. Eligible applicants must demonstrate financial need, maintain a minimum 2.0 GPA, and enroll full-time at an accredited institution. The scholarship fosters educational growth and community development, ensuring that residents have the necessary resources to succeed in their academic endeavors.

The PLTW Launch program, in partnership with Ardagh Group, aims to enhance educational opportunities for over 500,000 PreK-12 students and train more than 5,000 teachers in U.S. communities. This initiative focuses on program expansion, enabling schools to implement additional PLTW Launch modules and improve access to quality education. By fostering a robust educational framework, Ardagh and PLTW are committed to building vibrant, successful communities through sustainable educational practices.

The Trails Capacity Program, previously known as the Trail Fund Grant, aims to enhance community capacity for trail maintenance, research, and stewardship training across the nation. The program focuses on supporting non-Forest Service Federal lands, as well as state and local areas, fostering inclusivity and improved user behavior. By collaborating with diverse trail partners, it seeks to ensure effective stewardship and sustainable trail management, ultimately promoting public access and enjoyment of America's natural landscapes.

About us

SIR Foundation is a scientific foundation dedicated to fostering research in interventional radiology for the purposes of advancing scientific knowledge, increasing the number of skilled investigators, and developing innovative therapies that lead to improved patient care and quality of life. The foundation is committed to fostering the development and enhancement of innovative, minimally invasive, image-guided therapies from inception to mature clinical application and to conduct educational programs in the service of its mission.

Excellence in Innovation Award

Fund compelling, novel ideas that lead to improved health outcomes in IR.

About

Interventional radiologists create and introduce novel, minimally invasive procedures and devices that help solve some of our toughest medical challenges. To continue this rich history of innovation in IR, the purpose of this award is to fund compelling, novel ideas that lead to improved health outcomes in IR.

Innovation, for this purpose, is broadly defined as any use of emerging methods, new devices, new procedures or new technologies, such as artificial intelligence and nanotechnology, that display an exceptional degree of potential for transforming and advancing the specialty of interventional radiology.

The Annual Meeting Research Award Committee selects one recipient for this award each year.

The recipient will receive:

• Complimentary annual meeting registration
• Travel stipend up to $1,000
• The opportunity to present their research as well as meet peers, network with senior scientists and participate in learning opportunities at the SIR Annual Scientific Meeting
• Recognition during the SIR Annual Scientific Meeting

American Academy of Family Physicians Foundation

The AAFP Foundation focuses on improving health for everyone, and your support makes an immediate impact on the good work we do—from leadership development and education scholarships to funding social and health care services.

The AAFP Foundation strives to create a sense of belonging through an inclusive environment that embraces the family medicine community by recognizing individual uniqueness and contributions to family medicine.

Richard D. Feldman, M.D. Student and Resident Essay Contest

Each year, the Center for the History of Family Medicine (CHFM) sponsors a contest to encourage medical students and family medicine residents to write scholarly essays relevant to the history of family medicine in the United States. The first-place winner will receive $2,000 and the second-place winner will receive a $1,000 award.

We encourage all to apply and are committed to developing scholarly essays relevant to the history of Family Medicine in the United States by medical students and residents who reflect the rich diversity of the specialty and the patients served.

The PLTW Launch program, supported by Ardagh Group, aims to enhance education in local communities over the next decade. This initiative is set to benefit over 500,000 PreK-12 students and provide exceptional training to more than 5,000 teachers across 2,000 U.S. schools. As a global supplier of sustainable packaging solutions, Ardagh is committed to fostering educational opportunities that empower communities and promote equal access to quality education.

The Adapted PE/Activity Program of the Year Award recognizes outstanding community-based initiatives aimed at enhancing the physical capabilities of individuals with disabilities. Organized by SHAPE America, this award highlights programs that provide inclusive physical education and recreational opportunities, ensuring that all participants can engage in healthy, active lifestyles. By showcasing best practices, the award promotes innovation and advocacy for individuals with disabilities, fostering an environment of inclusion and support in physical activity.

The Path to a Cure — Collaborative Research Grant, offered by the Cystic Fibrosis Foundation, aims to support research in developing new therapies for cystic fibrosis, particularly focusing on CFTR gene repair and replacement strategies. This program prioritizes collaborations that integrate new investigators and innovative technologies into CF research. Applicants can request up to $1,000,000 annually for three years, with proposals requiring preliminary data to demonstrate feasibility and potential impact.

The Teaching Health Center Graduate Medical Education (THCGME) Program aims to ensure the sustainability of primary care residency training in community-based ambulatory patient care centers. By providing essential funding, this program supports the development of healthcare professionals who are equipped to deliver high-quality care, particularly in rural and underserved areas, enhancing the capacity to meet diverse health needs across various populations.

The Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRC) program is designed to enhance research on muscular dystrophy through a collaborative, center-based approach. By fostering interdisciplinary projects and providing essential training for emerging scientists, the MDSRCs aim to drive innovation in both basic and clinical research. Engaging patient and advocacy communities is a key component, ensuring research is patient-centered and informed by real-world needs. This initiative is supported by various legislative authorities.

The Suzanne G. Cusick Professional Development Fund, offered by the American Musicological Society, provides $500 grants to support low-income scholars in music and sound studies. These grants aim to enhance professional development for independent scholars and contingent faculty who lack access to such opportunities. The fund emphasizes equitable participation, particularly for historically under-represented groups, ensuring a diverse range of recipients can benefit from this vital support.

About

What is FOXG1 Syndrome?

FOXG1 syndrome is a rare genetic neurodevelopmental disorder caused by a mutation in the FOXG1 gene. FOXG1 gene is one of the first and most important genes for early brain development and when impaired, causes developmental disabilities as well as medical complexities, including epilepsy.

Every child born with FOXG1 syndrome is unique as FOXG1 manifests as a spectrum where symptoms and severity vary between individuals. Our patient data shows characteristics of children with FOXG1 syndrome include: non-speaking, non-ambulatory, experience seizures, feeding problems, cortical vision impairment, movement disorders, and developmental delays. Less-severely-affected FOXG1 children often present with (ASD) Autism Spectrum Disorder as FOXG1 is an autism related gene. FOXG1 syndrome is found equally among both females and males and is geographically more prevalent where diagnostic testing is more advanced. 

Our Story & Mission

When our children were diagnosed with FOXG1 syndrome, we were told there was nothing we could do. No treatments, no concerted research underway, no roadmap. Just a devastating diagnosis for a disorder few had ever heard of.

But we refused to accept that. 

Research Assets & Grants

FOXG1 Scientific Research Project Grants

The FOXG1 Research Foundation is providing grants to scientists to deepen the understanding of the biology of FOXG1 with the goal of identifying innovative therapeutic strategies and finding a cure.

For the next few years, these are the strategic focus areas:

• Experiments designed to understand when, where, and levels of FOXG1 needed for normal brain development in mice
• Experiments designed to understand the biophysical properties of FOXG1 mutations
• Experiments designed to gain insights into the molecular and cell biological pathways regulated by FOXG1  

Retina Research Foundation

Across the nation, there were only a handful of voluntary groups with the will and the means to tackle retinal disdorders. Retina Research Foundation, established in 1969, was one of those organizations. By the 1980s, RRF had become a voice for retina research in an effort to reduce the incidence of retinal disease, which was fast becoming the leading cause of blindness in developing countries.

Undaunted, the Foundation steadily raised funds each year for vision scientists who were nationally recognized for their work in retina research. Government funding for eye research increased dramatically, and the field of retina research matured. As this body of knowledge grew, RRF programs were expanded to include major awards that recognize established retina scientists and contribute to their ongoing research. The Foundation also developed scientific exchange programs to disseminate knowledge of the dramatic advances that were being made in the laboratory.

RRF Pilot Study Grants

The mission of the Retina Research Foundation is to reduce retinal blindness worldwide by funding programs in research and education. As a public charity, RRF raises funds from the private sector and the investment of its endowment funds.

RRF is currently welcoming pilot study grant applications for the 2027 grant period. Each grant application must be signed by the principal investigator and either their Department Chair or Dean of Research.

American College Of Sports Medicine Foundation Inc

ACSM is the largest sports medicine and exercise science organization in the world, with nearly 50,000 international, national and regional members and certified fitness professionals.

Our Mission: To educate and empower professionals to advance the science and practice of health and human performance.

GSSI Pathways in Sports Science Award | Graduate Student Research & Mentorship Award

GSSI celebrates the passion, resilience, and academic excellence of first-generation college students pursuing graduate degrees in exercise physiology, sports science, kinesiology, and/or sports nutrition. Designed to empower emerging leaders in the field, the award recognizes individuals who are breaking new ground, not only in their families but in the science of human performance.

In addition to research funding, to help promote professional development, award winners will receive one year of 1:1 mentorship from a GSSI scientist. Award winners will also receive complementary registration to ACSM’s 2027 Annual Meeting in Indianapolis, IN.

ACSM requires award winners to:   

• Submit official transcripts if selected as an award winner, 
• Attend the 2027 ACSM Annual Meeting in Indianapolis, IN. 
• Present funded research at a future ACSM Annual Meeting, and   
• Send ACSM a copy of any publications or presentations related to the funded research. 

This grant mechanism will focus on furthering the development of novel strategies towards improving the treatment of Small Cell Lung Cancer (SCLC). Work supported through this mechanism will address important areas of need across the entire care continuum and have the immediate potential to increase survivorship. It is expected that correlative translational research will be proposed that will enhance the understanding of SCLC.The overarching theme of the proposals should be centered around understanding the biology of SCLC and developing strategies toward improving outcomes for patients with SCLC. We will encourage applications on a wide variety of topics related to SCLC, including but not limited to the following:

• Advanced Screening and Diagnostic Technologies
  • Utilize liquid biopsies and circulating tumor DNA (ctDNA) to enhance early detection and monitoring of SCLC, providing non-invasive diagnostic and prognostic solutions
  • Investigate the clinical utility of blood-based biomarkers for improving SCLC diagnosis, monitoring treatment response, and predicting outcomes
  • Leverage artificial intelligence for the early detection of SCLC

• Disease Progression and Acquired Resistance
  • Study of molecular + clinical characteristics of rapid progressors vs. long-term responders in SCLC to tailor personalized treatment approaches
  • Leverage radiomics to identify predictive or prognostic factors such as treatment response, risk of pneumonitis, and likelihood of brain metastases
  • Investigate the underlying mechanisms of primary and acquired resistance to chemotherapy and immunotherapy in SCLC
  • Identify and validate biomarkers indicative of disease progression and/or therapeutic resistance

• Biomarkers and Immuno-Oncology
  • Identify and validate biomarkers that can predict greater responses to immunotherapy treatments in SCLC, enhancing patient selection and treatment efficacy

• Biospecimen-based research
  • Leverage real-world patient tissue and/or blood samples to enable:
    • Longitudinal studies of SCLC progression from limited-stage to extensive-stage disease
    • Investigation of tumor and microenvironmental changes before, during, and after treatment to understand the evolution of resistance
  • Develop a centralized infrastructure for biospecimen collection, with standardized protocols and accessible repositories to facilitate broad research collaboration

These awards provide a maximum of $500,000 in funding over a period of three years.

The Journalism & Media Grant aims to promote inclusive narratives and accurate media that engage communities in democratic processes. It supports U.S.-based nonprofit organizations focused on professional reporting, multimedia storytelling, and civic media. The grant addresses barriers to media participation and fosters innovation in journalism, providing essential infrastructure for a diverse media landscape. While unsolicited proposals are not accepted, organizations can share ideas through a Letter of Inquiry (LOI).

The Klingenstein Third Generation Foundation's 'Transformation of Mental Health Care Program' seeks innovative research into improving mental health care access for children and adolescents, particularly from under-resourced backgrounds. Applications are invited for studies that build on promising pilot work, focusing on scalable delivery models and technology use. Eligible applicants are academic researchers based in the U.S. who can demonstrate rigorous research capabilities. The foundation plans to award up to two grants of $100,000 each year for two years.

The grant mechanism will focus on furthering the development of strategies towards improving the outcomes of Small Cell Lung Cancer (SCLC) patients through patient advocacy. Work supported through this mechanism will address important areas of need across the entire care continuum and have the immediate potential to increase research efforts, quality of life and survivorship. The overarching theme of the proposals should be centered around using patient advocacy as a tool to develop strategies toward improving outcomes for patients with SCLC. We will encourage applications on a wide variety of topics related to SCLC, including but not limited to the following:

• Patient-Centric Care Models
  • Develop and implement care models that prioritize patient needs and preferences, integrating innovative approaches from diagnosis through survivorship
• Advanced Screening and Diagnostic Technologies
  • Create comprehensive survivorship care plans addressing long-term healthcare needs, focusing on follow-up care, monitoring for recurrence, and managing chronic side effects

• Access and Equity
  • Investigate barriers to accessing quality care, clinical trials, screening and biomarker testing for SCLC patients and purpose solutions to ensure equitable healthcare delivery for diverse populations

• Technology Integration
  • Explore the use of digital health tools and technologies to facilitate better patient-provider interactions, personalized care, and continuous monitoring during the care continuum
• Patient Feedback Mechanisms
  • Establish robust feedback systems to gather patient insights and experiences and use this data to inform continuous improvements in care delivery, diagnostic technologies, treatment approaches, clinical protocols and accessible repositories to facilitate broad research collaboration

The 2026 Strategies Using Patient Advocacy to Improve Outcomes in Small Cell Lung Cancer will grant a minimum of one award of $250,000 for a period two years ($125,000 per year).

The Hillman Emergent Innovation Grant offers $50,000 for 12-18 months to support innovative nursing-driven interventions for underserved populations facing health care access barriers, including racial minorities and low-income individuals. It encourages fresh, early-stage ideas targeting serious illness and end-of-life care challenges. By fostering community engagement and interdisciplinary collaboration, the program aims to transform care delivery in diverse settings, ensuring equitable health services for all.

The E. C. Lloyd & J.C.U. Johnson Scholarship Fund, established by Mrs. Mary Elizabeth Johnson, supports full-time students pursuing associate or bachelor’s degrees at accredited institutions in the U.S. The scholarship is renewable for up to four years for both undergraduate and graduate studies, contingent on maintaining eligibility standards. It can cover tuition, housing, supplies, books, and fees. However, awards depend on available assets, and future funding is not guaranteed.

The Youth Incentive Award, established by the Coleopterists Society, encourages students in grades 7-12 to explore the fascinating world of beetles. Annually, up to $1200 is awarded, with two grants of $400 and $800 for junior and senior categories, respectively. Recipients also receive a subscription to The Coleopterists Bulletin. The program aims to promote beetle studies, develop essential life skills, and provide financial support for educational projects, fostering a passion for entomology among youth.

The AAS Northeast Asia Council (NEAC) Distinguished Speakers Bureau Grant invites applications from U.S. and Canadian colleges to host distinguished scholars for public lectures on Japan and Korea. This program, initiated in 2011, aims to foster engagement with early career scholars and enhance East Asian studies. Grants cover honoraria of $500 and additional funding for in-person events, promoting accessibility and academic collaboration. Institutions are encouraged to apply every three years, ensuring support for smaller programs in Asian studies.