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Best Private Grants for Nonprofits in South Carolina

Find the perfect Private grants for nonprofits in South Carolina on Instrumentl. 9,000+ Private grants for nonprofits in South Carolina in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,441 Results based on applied filters

MRF Breakthrough Consortium (MRFBC) Young Investigator Team Award to Advance the Field of Translational Immuno-Oncology

Melanoma Research Foundation
Private
United States
Up to US $150,000
The MRFBC Young Investigator Team Award supports innovative research in immuno-oncology for melanoma, offering up to $150,000 annually for two years. This funding targets U.S.-based researchers aiming to enhance clinical outcomes for melanoma patients or deepen the scientific understanding of immuno-oncology. The MRF collaborates with key institutions to address challenges in melanoma research, fostering partnerships that maximize research potential and impact.
Cancer / Oncology Skin Diseases & Dermatology Pediatric Cancers

Melanoma: Established Investigator Award

Melanoma Research Foundation
Private
United States
Up to US $125,000
The Melanoma Established Investigator Award offers up to $125,000 annually for two years, aimed at established melanoma researchers or senior researchers transitioning into melanoma research. Eligible applicants include Associate Professors or higher, with both tenured and non-tenured faculty encouraged to apply. U.S. citizenship is not a requirement for this funding opportunity provided by the Melanoma Research Foundation.
Cancer / Oncology Pediatric Cancers Skin Diseases & Dermatology

Miller Indigenous Economic Development Fellowship

Native Forward Scholars Fund
Association/Society
United States
Unspecified amount
The Miller Indigenous Economic Development Fellowship, established by the Native Forward Scholars Fund, provides financial assistance to American Indian and Alaska Native doctoral candidates engaged in economic research impacting Native communities. This fellowship supports costs associated with data collection, analysis, and travel. It aims to enhance the representation of Native scholars in economics, addressing the current underrepresentation in the field. Eligible candidates are encouraged to apply to further their research and contribute to their communities.
Education - Higher Education Academic Success & Enrichment Native American Services +3 more

SAF National Awards Program: Young Forester Leadership Award

Society of American Foresters (SAF)
Association/Society
United States
More than US $500
The Young Forester Leadership Award, presented by the Society of American Foresters (SAF), recognizes exceptional leadership from young forestry professionals under 40 years old. This award highlights contributions to forestry through innovative projects and sustained leadership roles. Recipients receive a $500 honorarium, complimentary registration for the SAF national convention, and support for travel expenses up to $500. This prestigious accolade aims to encourage the next generation of forestry leaders to excel in their professional endeavors.
Forestry

HIV/AIDS Clinical Trials Network Leadership and Operations Centers

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is calling for applications for four Leadership and Operations Centers (LOCs) as part of its HIV/AIDS Clinical Trials Network initiative. These LOCs will guide research on HIV therapeutics, prevention, and treatment strategies across diverse populations. The initiative aims to enhance evidence-based practices and improve health outcomes for individuals affected by HIV, ultimately contributing to the goal of ending the HIV epidemic.
HIV / AIDS

HIV/AIDS Clinical Trials Network Laboratory Centers

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is launching a funding opportunity for up to four Clinical Trials Network Laboratory Centers (LCs). These LCs will support HIV prevention and treatment strategies by providing necessary laboratory infrastructure and technologies for clinical trials. They will ensure rigorous laboratory testing and oversight, enhance sample integrity, and utilize advanced data management systems to meet evolving demands in HIV research and testing.
HIV / AIDS

Bonnie Sorenson Scudder Scholarship

Community Foundation of Northern Illinois
Private
United States
Unspecified amount
The Bonnie Sorenson Scudder Scholarship aims to support female students aspiring to become teachers, particularly those passionate about women's physical education. Established in memory of Bonnie Sorenson Scudder, a dedicated physical education teacher at Harvard High School, this scholarship encourages future educators to continue her legacy. For more details, contact Marcia Miller at Harvard High School.
Academic Scholarship Programs Education - Higher Education Kinesiology & Sports Medicine +3 more

HIV/AIDS Clinical Trials Network Clinical Trials Units

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is launching a funding opportunity for Clinical Trials Units (CTUs) as part of its effort to combat HIV/AIDS. This initiative aims to support innovative clinical trials and implementation research to improve prevention and treatment strategies. With a focus on both domestic and international research sites, CTUs will play a crucial role in addressing the HIV epidemic and enhancing participant recruitment and retention. This funding opportunity is authorized under the Public Health Service Act.
HIV / AIDS

ASF Olin Fellowships

Atlantic Salmon Federation (ASF)
Private
Canada, United States
C $1,000 - C $3,000
The Atlantic Salmon Federation Olin Fellowships support individuals aiming to enhance their knowledge and skills in salmon conservation and management. These fellowships are available annually for various pursuits, including research and graduate studies, without the requirement of being enrolled in a degree program. Eligible applicants must be legal residents of the U.S. or Canada, and the fellowships can be conducted at accredited institutions or active management programs.
Ichthyology (Fish) Fisheries

Gary S. Wilmer / RAMI Music Scholarship

Community Foundation of Northern Illinois
Private
United States
Unspecified amount
The Gary S. Wilmer / RAMI Music Scholarship supports local students aged 19 and under who are passionate about music and committed to furthering their education in the arts. Established in memory of Gary Wilmer, founder of RAM Magazine, this scholarship honors his legacy by providing financial assistance to aspiring musicians in Boone, Ogle, or Winnebago County. Applicants are required to submit an audition recording and a reference from a music teacher to demonstrate their dedication to musical excellence.
Music Education - Higher Education Academic Scholarship Programs +2 more

Milton & Phyllis Berg Family Respite Care Grants

Alzheimers Foundation Of America Inc
Private
United States
US $6,000
The Milton & Phyllis Berg Family Respite Care Grants, offered by the Alzheimer’s Foundation of America, support member organizations in providing respite care scholarships to families affected by Alzheimer's. This initiative enhances the quality of life for both individuals and caregivers by promoting social engagement and offering essential breaks for caregivers. Grants are awarded biannually in memory of Barry E. Berg's parents, who faced Alzheimer's and caregiving challenges.
Dementia & Alzheimer’s Disease Caregiver Support / Respite Care

HIV Care Grant Program - Part B States/Territories Formula and AIDS Drug Assistance Program Formula and AIDS Drug Assistance Program Supplemental Awards: Pacific Islands Jurisdictions

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $300,000
The HIV Care Grant Program aims to enhance access to comprehensive, high-quality HIV care and treatment for low-income individuals in Pacific Island territories. Funded by the US HHS: Health Resources & Services Administration (HRSA), this initiative supports states and territories in developing effective systems of care, ensuring that those affected by HIV receive the necessary treatment and support to improve health outcomes.
HIV / AIDS

Jack Kent Cooke Foundation: Young Scholars Program

Jack Kent Cooke Foundation
Private
United States
Unspecified amount

Jack Kent Cooke Foundation

The Jack Kent Cooke Foundation is dedicated to advancing the education of exceptionally promising students who have financial need. Since 2000, the Foundation has awarded $304 million in scholarships to more than 3,400 students from 8th grade through graduate school, along with comprehensive academic advising, career pathway counseling and other support services. The Foundation has also provided $136 million in grants to organizations that serve such students.

The Jack Kent Cooke Foundation’s scholarship programs are designed to encourage and support outstanding students who work hard and have financial need. Our scholarships provide financial assistance and academic support to high school, undergraduate, and graduate students. In addition to the monetary award, students join a thriving network of more than 3,400 Cooke Scholars.

Young Scholars Program

The Cooke Young Scholars Program is a selective five-year, pre-college scholarship for exceptionally promising 7th grade students with financial need. It provides comprehensive academic and college advising, as well as financial support for school, Cooke-sponsored summer programs, internships, and other learning enrichment opportunities.

Program Experience

Educational Advisers support Young Scholars to maximize high school experiences and to go on to thrive at the nation’s top-performing colleges. Our programming and support may include:

  • Identifying an appropriately rigorous high school.
  • Engaging in four-year planning and goal-setting.
  • Funding for academic and extracurricular opportunities, such as music and art lessons, supplemental academic classes and technology.
  • Annual summer programs, including two required Young Scholar programs.
  • Year-round Young Scholars community programming.
  • Networking opportunities with a high-achieving peer community.

Academic Success & Enrichment After School / Summer Educational Programs Career / College Preparation +2 more

Identifying the Effects of GLP-1 Medications Among Individuals with Cardiovascular, Kidney and Metabolic Disease

American Heart Association
Association/Society
United States
Up to US $300,000
The American Heart Association is inviting proposals for research on the effects of GLP-1 and GIP agonists in individuals with cardiovascular, kidney, and metabolic diseases. This initiative aims to explore how these medications can alleviate the CKM burden. Researchers with expertise in causal inference, machine learning, and cardiovascular research are encouraged to apply, particularly those working in multidisciplinary teams and leveraging various data sources.
Cardiovascular Diseases & Systems Endocrine & Metabolic Diseases Kidney Diseases

The Longleaf Fund Grant

Foundation for the Carolinas
Private
Cumberland County, North Carolina, Edgecombe County, North Carolina +4 more
US $10,000 - US $150,000
The Longleaf Fund Grant supports capital projects aimed at enhancing the lives of at-risk children and youth across the Carolinas. Focusing on building accessible play spaces, promoting educational technology, and improving environments for children with disabilities, this grant encourages community engagement and collaboration. Eligible projects must be completed within 12-18 months and demonstrate significant community support. The fund prioritizes initiatives that address the needs of vulnerable populations and can secure additional funding.
Youth Services Children With Disabilities Technology Access & Digital Literacy +4 more

Guidelines to Develop Best-In-Class Maintenance Strategies for Vertical Assets RFP

Water Research Foundation
Private
Countries
Up to US $250,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5415 - Guidelines to Develop Best-In-Class Maintenance Strategies for Vertical Assets

Grant Information

  • Develop a clear understanding of the background and benefits associated with implementing well-rounded maintenance strategies for vertical assets.
  • Develop a structured approach to identify and implement best-in-class maintenance strategies for vertical assets that improve reliability, increase asset availability, reduce unplanned work and emergency shutdowns, support the transition from reactive to proactive maintenance, and minimize total lifecycle cost.
  • Apply leading practices such as Reliability Centered Maintenance (RCM) and cutting-edge technologies and analytics to vertical assets.
Water Resource Management

Indigo Hope Foundation: At-Risk Youth Development Grant

The Indigo Hope Foundation
Association/Society
Abbeville County, South Carolina, Anderson County, South Carolina +8 more
US $500 - US $100,000

Indigo Hope Foundation: At-Risk Youth Development Grant

Empowering programs that provide mentorship, education, life skills training, and opportunities for young people facing challenges.

Key Focus Areas:

  • Mentorship Programs
  • Educational Support
  • Life Skills Training
  • Career Development

Example Programs We Fund:

  • After-school tutoring and mentorship
  • Job readiness training
  • Leadership development
Workforce Preparation & Job Readiness Career / College Preparation Youth Development & Leadership

Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R01 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This grant opportunity from the US Department of Health and Human Services, specifically the National Institutes of Health, aims to examine the effectiveness of family navigation models that divert non-urgent mental health concerns from emergency departments. The initiative seeks to enhance mental health service engagement, provide necessary resources, and support families in overcoming barriers to help-seeking. Key deadlines for applications range from February 2025 to October 2027.
Mental Health & Psychiatric Diseases Children’s Mental Health Emergency Medical Care & Services

Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
This NOFO aims to enhance research on the effectiveness and implementation of family navigation models that divert non-urgent mental health concerns from emergency departments. It will focus on tools for triaging mental health acuity, engaging families with necessary services, and addressing barriers to help-seeking. Important deadlines for grant applications range from February 2025 to October 2027, with optional Letters of Intent encouraged thirty days prior to each due date.
Mental Health & Psychiatric Diseases Children’s Mental Health Emergency Medical Care & Services

The Anne and Tony Hillerman Scholarship

Albuquerque Community Foundation
Private
New Mexico, United States
Unspecified amount
The Anne and Tony Hillerman Scholarship, part of the New Mexico Press Women Scholarship Fund, supports New Mexico students pursuing undergraduate or graduate degrees in journalism or communications. Established in 2023, the fund promotes ethical journalism and offers networking opportunities through the NMPW Annual Conference. Eligible applicants must be enrolled in a relevant program, provide a portfolio of work, and submit a personal essay detailing their interests and career goals. This scholarship fosters the next generation of communicators and advocates for First Amendment rights.
Education - Higher Education Vocational & Trade Education Career / College Preparation +3 more

Carl Hill Memorial Scholarship

Delaware Community Foundation
Private
United States
US $500

Carl Hill Memorial Scholarship

Awards:

  • One time award of $500.
Education - Higher Education Financial Literacy Business Education +1 more

Ryan White HIV/AIDS Program (RWHAP) Integrated HIV/AIDS Planning Resource Allocation Cooperative Agreement

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $700,000
The Ryan White HIV/AIDS Program (RWHAP) Integrated HIV/AIDS Planning Resource Allocation Cooperative Agreement aims to enhance the effectiveness of HIV prevention and care planning for RWHAP Parts A and B recipients. Through the provision of training, tools, and technical assistance, this initiative seeks to optimize resource allocation and strengthen the overall system of HIV care and treatment, ultimately improving health outcomes for those affected by HIV.
HIV / AIDS

AIDS Drug Assistance Program (ADAP) Emergency Relief Funds (ERF) (363159)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $10,000,000
The AIDS Drug Assistance Program (ADAP) Emergency Relief Funds aim to provide essential funding to states and territories. This initiative focuses on preventing, reducing, or eliminating waiting lists for ADAP services, ensuring timely access to necessary medications and support for individuals living with HIV/AIDS. This program addresses critical funding shortfalls, enhancing the healthcare infrastructure and improving health outcomes in affected communities.
HIV / AIDS

Ryan White HIV/AIDS Program Part C Capacity Development Program (363166)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $150,000
The Ryan White HIV/AIDS Program Part C Capacity Development Program aims to enhance the capabilities of community-based organizations, focusing on improving health outcomes and decreasing HIV transmission. This initiative supports individuals who have not yet accessed regular HIV care, emphasizing innovative care solutions and infrastructure development to address these critical needs.
HIV / AIDS

HIV Care Grant Program - Part B States/Territories Formula and AIDS Drug Assistance Program Formula and AIDS Drug Assistance Program Supplemental Awards

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The HIV Care Grant Program, funded by the US HHS: Health Resources & Services Administration (HRSA), aims to enhance access to high-quality HIV care and treatment for low-income individuals. This initiative supports states and territories in developing comprehensive systems to address the needs of those living with HIV. By providing essential resources, the program seeks to improve health outcomes and ensure that vulnerable populations receive the necessary support and services.
HIV / AIDS

Ryan White HIV/AIDS Program Part B States/Territories Supplemental Grant Program (363163)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $9,000,000
The Ryan White HIV/AIDS Program Part B Supplemental Grant aims to provide essential funding to support HIV care and treatment services across states and territories. This program supplements existing formula-based funding from the RWHAP Part B and ADAP, improving access to necessary resources for those affected by HIV/AIDS. By enhancing support structures, it addresses critical healthcare needs, ensuring better health outcomes for vulnerable populations.
HIV / AIDS

SAF National Awards Program: Outstanding Local Unit Achievement Award

Society of American Foresters (SAF)
Association/Society
United States
More than US $500
The SAF National Awards Program celebrates outstanding contributions to forestry through various awards, including the Outstanding Local Unit Achievement Award. This award recognizes local units for their sustained leadership or special projects that benefit the Society of American Foresters and the forestry profession. Each awarded unit receives a $500 honorarium, complimentary convention registration, and funding for travel expenses, ensuring recognition and support for their impactful efforts in forestry.
Forestry

Private Grants for Nonprofits in South Carolina Highlights

Looking for private grants for nonprofits in South Carolina?


Read more about each grant below or start your 14-day free trial to see all private grants for nonprofits in South Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Private Grants for Nonprofits in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Private grants for nonprofits in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Private grants for nonprofits in South Carolina over $25K in average grant size

40 Private grants for nonprofits in South Carolina over $50K in average grant size

32 Private grants for nonprofits in South Carolina supporting general operating expenses

100+ Private grants for nonprofits in South Carolina supporting programs / projects

2,000+ Grants on Instrumentl focused on Art & Culture

500+ Grants on Instrumentl focused on Writing & Literature

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Private grants for Nonprofits in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
25.2%
Q3
24.8%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Private Grants for Nonprofits in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$535,356 $535.4 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Private Grants for Nonprofits in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Private Grants for Nonprofits in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Private Grants for Nonprofits in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081