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Best Unrestricted Grants for Nonprofits in South Carolina

Find the perfect Unrestricted grants for nonprofits in South Carolina on Instrumentl. 9,000+ Unrestricted grants for nonprofits in South Carolina in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,447 Results based on applied filters

Providers Clinical Support System – Universities

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Providers Clinical Support System – Universities program aims to equip graduate-level health professional students with the necessary skills to understand, identify, intervene, and treat patients with substance use disorders. By focusing on practical training and comprehensive education, this initiative prepares future practitioners to effectively address the challenges associated with substance misuse, ensuring they are well-prepared upon obtaining their licenses.
Education - Higher Education Workforce Preparation & Job Readiness Addiction & Substance Use Disorders +1 more

Inter American Press Association: Awards for Excellence in Journalism

Inter American Press Association
Association/Society
Argentina, Bolivia +21 more
US $2,000
The Inter American Press Association (IAPA) is inviting media professionals from North America, Latin America, the Caribbean, and Spain to participate in the Awards for Excellence in Journalism. This prestigious competition features 14 categories, including Migration Journalism and Sustainability, to highlight significant contributions in journalism. Open to works published in Spanish, English, or Portuguese, the contest encourages broad participation. Winners will receive awards, with many categories offering prizes of US$2,000.
Journalism News Media & Communications Science Communications +1 more

Emerging Leaders Program Alumni Award

Soil and Water Conservation Society (SWCS)
Association/Society
United States
US $500

About Us

The Soil and Water Conservation Society (SWCS) is the premier international organization for professionals who practice and advance the science and art of natural resource conservation.

SWCS Emerging Leaders Program Alumni Award

The Emerging Leader Alumni Award recognizes outstanding alumni of the Emerging Leaders Program (ELP) who have demonstrated a commitment to conservation leadership and active participation in the Soil and Water Conservation Society (SWCS). Three $500 cash awards will be granted to support professional development, Society membership, conference fees, or other career-enhancing opportunities.

Freshwater Conservation Green Infrastructure Civic Leadership Development

Alkermes Pathways Research Awards

Alkermes
Corporate
United States
Up to US $100,000
The Alkermes Pathways Research Awards program aims to foster research in neuroscience, specifically targeting schizophrenia and bipolar disorder. With grants up to $100,000, it supports early-career investigators exploring critical areas, including sleep and circadian disturbances related to these conditions. This initiative addresses the urgent need for innovative solutions in mental health research, empowering the next generation of scientists to make impactful contributions in understanding and treating these complex disorders.
Schizophrenia Mental Health & Psychiatric Diseases Sleep

Emergency Citrus Disease Research and Extension Pre-Applications

USDA: National Institute of Food and Agriculture (NIFA)
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $15,000,000
The Emergency Citrus Disease Research and Extension Pre-Applications program, funded by the USDA's National Institute of Food and Agriculture, seeks innovative proposals to combat Huanglongbing (HLB) and its associated diseases. This initiative aims to ensure sustainable citrus production in the U.S. through collaborative strategies that leverage existing knowledge. Funded projects will focus on developing actionable solutions for growers to effectively manage and prevent HLB infections, ensuring the health of citrus crops in the near future.
Agriculture Agricultural Crops Sustainable Agriculture & Agroecology +1 more

Jean T. Grant Scholarship

The Columbus Foundation
Private
United States
US $1,000
The Jean T. Grant Scholarship, established by The Columbus Foundation, honors the legacy of Jean Terry Grant, a devoted librarian and arts advocate. Providing $1,000, this scholarship supports graduating seniors from Columbus City Schools pursuing studies in music or the arts. Jean's commitment to education and the arts inspires future generations, ensuring that her passion for creativity and philanthropy continues to impact the community positively.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Breast Cancer Community Education Grants for ONS Chapters

Oncology Nursing Society
Private
United States
Up to US $1,000
The Breast Cancer Community Education Grants, funded by the Oncology Nursing Foundation through AstraZeneca HealthCare Foundation, aim to enhance breast cancer awareness through nurse-led community education programs. Grants of up to $1,000 are available to ONS Chapters in the U.S., enabling them to implement impactful educational initiatives. Eligible activities must focus on community outreach and education, fostering a broader understanding of breast cancer.
Nursing Breast Cancer Community Health Education

Clinical Trials Addressing Unmet Needs of Rare Neurodegenerative Diseases (R01) Clinical Trials Required

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
US $650,000 - US $900,000
The US Department of Health & Human Services, through the FDA, is funding clinical trials targeting rare neurodegenerative diseases. This initiative aims to enhance treatment options by evaluating the efficacy and safety of new products for both children and adults. By fostering innovative and collaborative trial designs, the FDA seeks to accelerate the approval of new therapies, ultimately benefiting patients with rare conditions and advancing drug development in this critical area.
Pharmacology Drug Safety Neurological Diseases & Disorders +1 more

NetVUE Vocation across the Academy Grants

The Council of Independent Colleges
Association/Society
United States
Up to US $65,000

The Council of Independent Colleges

Founded in 1956, the Council of Independent Colleges (CIC) is an association of nonprofit independent colleges and universities, state-based councils, and higher education affiliates that works to support college and university leadership, advance institutional excellence, and enhance public understanding of independent higher education’s contributions to society.

CIC is the major national organization that focuses on providing services to leaders of independent colleges and universities and state-based councils. CIC offers conferences, seminars, publications, and other programs and services that help institutions improve educational quality, administrative and financial performance, student outcomes, and institutional visibility.

NetVUE Vocation across the Academy Grants

​One major purpose of an undergraduate education in the liberal arts is to help students shape a philosophy of life. At the same time, undergraduates today are increasingly preoccupied with postgraduate employment. The purpose of this grant program is to help colleges and universities develop more effective ways to strengthen the link between these two purposes of undergraduate education. It is designed to support institutions in their efforts to expand vocational exploration and discernment programs across the curriculum and co-curricular programs, with the following goals:

  • to help students develop more effective links between developing a philosophy of life and preparing for a career;
  • to include more faculty and students in the work of vocational exploration and discernment; and, in some cases,
  • to build connections with community partners, such as local businesses, nonprofits, and other community organizations.
Workforce Preparation & Job Readiness Education - Higher Education College Success / Persistence

Donald J. DeYoung Scholarship

Grand Rapids Community Foundation
Private
United States
US $2,000 - US $5,000

Grand Rapids Community Foundation

Connecting people, passion and resources

The Community Foundation is a nonprofit organization that connects people, passion and resources. With our partners, the Community Foundation uses the tools of philanthropy to find solutions to pressing issues. We provide grants to support the work of nonprofits, scholarships to local students and other forms of support to communities working to eliminate barriers to opportunity, prosperity and belonging.

Our Mission is to build and manage our community’s permanent endowment and lead the community to strengthen the lives of its people.

We envision a magnetic and interconnected West Michigan community.

Integrity, Excellence, Inclusion, Sustainability and Bold Aspirations

Give and Receive Openly, Build Trust with Each Other, Create Brave and Safe Space, Embrace Vulnerability, Accountability

Our North Star

For West Michigan to grow and prosper, we must make sure that everyone can apply their talents and creativity to fuel our future. It is only by connecting across perspectives and overcoming inequities that we can build and sustain an inclusive economy and thriving community.

Opportunities for students

Apply for scholarships to support your ambitions

Each year Grand Rapids Community Foundation supports hundreds of students on their college or career training journeys. We are excited to remove barriers to academic success so that students like you can pursue what you're passionate about.

Scholarship Fund Details

Support for West Michigan Students

Attending college or trade school increases opportunity and opens doors to careers. Donor partners who establish a scholarship fund give students a boost on their path to higher education. Students who complete the general scholarship application are considered for these scholarships.

Open to students who are current or former wards of the court in Kent County, Michigan pursuing an undergraduate college or vocational education, have financial need and a 2.5 minimum GPA.

Must provide a letter of recommendation from a caseworker.

Education - Higher Education Vocational & Trade Education College Success / Persistence +2 more

Promotion of Doctoral Studies Scholarships- Pre-candidacy Doctoral Students

Foundation for Physical Therapy Research
Private
United States
Up to US $45,000
The Promotion of Doctoral Studies Scholarships, offered by the Foundation for Physical Therapy Research, provides a $7,500 annual scholarship for doctoral students completing coursework at accredited institutions. Applicants may receive up to $15,000 in pre-candidacy scholarships and a total of $45,000 throughout their doctoral program. The Foundation encourages research in areas such as acute care, cardiology, pulmonary health, and PT education, fostering a new generation of skilled researchers in physical therapy.
Physical Therapy Medical Education & Professional Training Aging / Gerontology +2 more

Interventions on Health and Healthcare Disparities on Non-Communicable and Chronic Diseases in Latin America: Improving Health Outcomes Across the Hemisphere (R01 - Clinical Trial Required) (358157)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Central America +6 more
Unspecified amount
This funding opportunity aims to enhance health outcomes by tackling healthcare disparities in non-communicable and chronic diseases across Latin America. It encourages interdisciplinary research teams to collaborate with Latin American institutions, focusing on innovative clinical and community-based interventions. Applications are accepted for various deadlines between 2025 and 2027, with a particular emphasis on addressing significant health burdens experienced by U.S. Hispanics/Latinos. This initiative seeks to foster meaningful partnerships to improve health equity.
Health Disparities & Social Determinants of Health Health Care Access & Delivery Chronic Illnesses +1 more

Edith M. Pritchard Scholarship

Nurses Educational Funds Inc.
Private
United States
Unspecified amount
The Edith M. Pritchard Scholarship, offered by Nurses Educational Funds Inc., supports nurses pursuing master's or doctoral degrees in nursing education and public health. Applicants must hold a current RN license, maintain a GPA of 3.6, and have at least two semesters of study remaining post-award notification. This scholarship promotes nursing leadership and is funded through donations, reflecting over a century of commitment to nursing education.
Education - Higher Education Nursing Mental Health & Psychiatric Diseases +2 more

Child Neurology Foundation Summer Scholarship For Medical Students

Child Neurology Foundation
Corporate
Canada, United States
US $3,500
The Child Neurology Foundation offers a Summer Scholarship for first, second, or third-year medical students interested in neurodevelopmental disabilities or child neurology. This scholarship provides $3,500 for clinical research focused on neurodevelopmental disabilities in children or young adults, conducted under the supervision of a qualified subspecialist. Applications are evaluated based on their importance, originality, and contribution to the medical student's development.
Neurological Diseases & Disorders Children’s Health & Pediatrics Children With Disabilities +1 more

Epilepsy Scholarship

Community Foundation of Central Illinois
Private
United States
US $700

Who We Are

The Community Foundation of Central Illinois will make a sustainable philanthropic impact in our community through visible leadership in connecting people who care with causes that matter.

Epilepsy Scholarship Fund

The Epilepsy Scholarship Fund was established in memory of David S. Izard, who lived in Canton, Illinois, and was active in football, track, and basketball. He graduated from Western Illinois University and worked as an Assistant Manager at Wal-Mart in Georgia. Diagnosed with epilepsy at age 3½, David lived a full and active life. He passed away on December 5, 1992, just fifteen days before his 27th birthday. Additional contributions have also been made in memory of other individuals. 

The fund provides scholarships to students pursuing an education at a junior college or four-year college or university.

Education - Higher Education Epilepsy Educational Access & Equity

Llewellyn L. Cayvan String Instrument Scholarship

Grand Rapids Community Foundation
Private
United States
Unspecified amount

Generally the Community Foundation's scholarships are awarded to applicants who have high financial need. Applicants with household income exceeding $100,000 are less likely to be awarded, but applying will allow you to be considered for targeted scholarships.

Llewellyn L. Cayvan String Instrument Scholarship

Open to students studying music with concentration in viola, violin, violincello, or bass viol.

Performing Arts Classical Music Music Education

Gropper Clement Legacy Scholarship

South Dakota Community Foundation
Private
United States
Unspecified amount

Gropper Clement Legacy Scholarship

To provide financial support to graduates of Huron, James Valley Christian, Kadoka and Miller High Schools.

Education - Higher Education Diabetes Physical Disabilities

Behavioral Health Integration Initiative

Indian Health Service
Federal Government
United States
Unspecified amount
The Behavioral Health Integration Initiative aims to enhance the health of American Indian and Alaska Native individuals by expanding access to integrated behavioral health care. It supports Tribal and Urban Indian Organization health systems in providing culturally responsive and trauma-informed services. The initiative focuses on improving care coordination, promoting early identification of mental health issues, and integrating various health services to improve overall health outcomes and quality of life for AI/AN communities.
Mental Health & Psychiatric Diseases Wellness & Healthy Living Native American Services +1 more

Transportation Research and Policy

Arnold Ventures
Private
United States
Up to US $200,000

Transportation Research and Policy

Arnold Ventures (AV) is a philanthropy dedicated to improving the lives of all Americans through evidence-based solutions that maximize opportunity and minimize injustice.

The Infrastructure team has been investing in efforts to build better, faster, and lower-cost infrastructure with a focus on housing, energy, and transportation. For transportation, we are investing in policymaking and research that tackles the inefficiencies that make U.S. transportation infrastructure so difficult and expensive to build. 

Purpose

Transportation policy represents an avenue for improving the systems moving people, goods, and services. The Infrastructure team is seeking proposals evaluating the effectiveness and/or benefits of existing transportation or transportation-adjacent policies on outcomes for communities in the United States.

Eligible Projects and Topic Areas of Interest

This Request for Proposals (RFP) aims to bolster the knowledge base of potentially effective policies, programs, and interventions by funding efforts that align with key AV Infrastructure policy areas.

AV is primarily focused on traditional surface transportation — road and public transit — but is open to proposals in aviation, maritime, passenger and freight rail, trucking, and more.

We seek proposals for: 1) research, expanded data sets, or analysis; 2) administrative or legislative policy reforms at the federal, state, or local level; or 3) models of effective implementation including proposals for implementing agencies to partner with researchers or program evaluators to conduct baseline and post-intervention research on implementation effectiveness that will advance the knowledge base and provide illustrative examples within, but not limited to, the following topic areas:

  • Transportation Capital Investment Reform. Evaluating how capital funding is prioritized and selected at the federal, state, or regional level, including discretionary grant programs and formula-based funding. What reforms could ensure projects deliver higher public returns?
  • Cost Estimation, Oversight, and Accountability. Why do major transportation projects frequently exceed budgets and timelines, and how can we identify strategies to improve transparency, cost realism, and performance oversight?
  • Access in Mobility Outcomes. Measuring how current transportation investments affect access to jobs, services, and economic opportunities for workers and families, and what policy changes could improve access.
  • Performance-Based Project Selection. How can public agencies shift from current, politically driven allocations to datadriven, performance-based decision-making on capital project selections?
  • Institutional Barriers to Reform. What organizational, legal, or procedural hurdles prevent DOTs and MPOs from adopting better practices (e.g., outcome-based planning, integrated land use/transportation policy)?
  • Permitting and Permit Reform. How do current local, state, and federal permitting practices affect project cost, quality, timeline, and other concerns?
  • Intergovernmental Dynamics. How do federal, state, and local funding structures and requirements enable or constrain effective transportation investment? What governance structures would improve outcomes when it comes to transportation planning and project delivery?
  • Data Sets and Root Causes of High Delivery Costs. Expanded data sets on unit costs and/or research illuminating the root causes of why transportation and transit projects cost so much and take so long to deliver. What policy and practice changes could manage project delivery risks and improve the likelihood that projects will be delivered on s chedule and on budget?
  • Domestic Content. How do Buy America and domestic content requirements affect the cost, speed, innovation, and effectiveness of transportation infrastructure projects?
  • Procurement Process. How do current procurement practices affect project cost, quality, innovation, and accountability — and what policy and regulatory reforms could improve outcomes?
  • Other. AV also welcomes innovative proposals on other transportation issues that align with our mission.

These research, policy development, and implementation proposals can be relevant to federal surface transportation reauthorization legislation or federal administrative changes; state reforms to Departments of Transportation; and/or local-level reforms relevant either to regional transportation agencies, transit agencies, or municipal governments.

Public Policy Public Transportation & Mass Transit Systems Public Infrastructure

Elisa B. Hughey Scholarship for the Arts

Cattaraugus Region Community Foundation
Private
United States
US $500 - US $1,000

Elisa B. Hughey Scholarship for the Arts

Scholarships will be awarded annually from this fund for college-bound students from any Cattaraugus County High School committed to advancing their skills in any aspect of the arts. Preference will be for graduating seniors of Ellicottville, Cattaraugus-Little Valley, West Valley, Salamanca or Franklinville/Ten-Broeck Academy high schools. First preference will be for students pursuing the fine arts, with second preference for students pursuing performing arts fields. This award is not limited to students majoring in art.

Education - Higher Education Performing Arts Fine Art +2 more

Allison Adams Wieczorek Scholarship

Nurses Educational Funds Inc.
Private
United States
Unspecified amount
The Allison Adams Wieczorek Scholarship supports graduate nurses pursuing degrees in maternal-infant and pediatric nursing. Established through the Nurses Educational Funds, Inc., this scholarship honors the contributions of Allison Adams Wieczorek, a dedicated board member with extensive experience in financial services. Applicants must have at least two semesters of study remaining and meet specific eligibility criteria, including holding a current RN license and maintaining a minimum GPA of 3.6. This initiative fosters nursing leadership and education.
Education - Higher Education Nursing Mental Health & Psychiatric Diseases +2 more

Rural Communities Opioid Response Program - Evaluation

Health Resources and Services Administration
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The Rural Communities Opioid Response Program - Evaluation aims to assess the effectiveness of behavioral health strategies in rural settings. By developing evaluation tools and resources, this initiative seeks to empower local communities in their health initiatives, ensuring that future programs are informed by comprehensive evaluations. Funded by the Health Resources and Services Administration, the program highlights the importance of tailored approaches to address opioid-related challenges in rural areas.
Mental Health & Psychiatric Diseases Addiction & Substance Use Disorders Rural Development +1 more

Davis-Kozoll Scholarship

Albuquerque Community Foundation
Private
United States
US $1,000 - US $5,000
The Davis-Kozoll Scholarship, established in 2019 by the Sandia Foundation, supports students from northwest New Mexico pursuing higher education in science or human service disciplines. Scholarships range from $1,000 to $5,000 and can be renewed annually based on academic progress. Applicants must have a minimum GPA of 2.0, demonstrate community ties, and may pursue various degrees or vocational certificates. Priority is given to students from specific local communities, enhancing educational opportunities in the region.
Education - Higher Education Vocational & Trade Education Career / College Preparation +2 more

Mechanisms that Impact Cancer Risk after Bariatric Surgery (R01 Clinical Trial Optional) (356341)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
The National Cancer Institute (NCI) is seeking applications for studies that explore how bariatric surgery influences cancer risk, emphasizing the need for innovative research in this area. This funding opportunity encourages the participation of researchers who focus on the long-term impacts of bariatric surgery beyond weight loss and diabetes, addressing critical gaps in understanding the disease mechanisms involved. Key deadlines for application submissions span from February 2025 to October 2027.
Cancer / Oncology Surgery Obesity

Seymour Siegel Youth Achievement Award

Jewish Community Foundation
Private
United States
Unspecified amount
The Seymour Siegel Youth Achievement Award, offered by the Jewish Community Foundation, provides financial support for high school students pursuing post-secondary education or vocational training. Open to applicants of the Jewish faith, this award prioritizes those from single-parent households, orphans, or foster children. Interested candidates must submit a personal narrative detailing their qualifications. The foundation, established in 1979, is a leading community resource in South Jersey, managing over $35 million in assets.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Unrestricted Grants for Nonprofits in South Carolina Highlights

Looking for unrestricted grants for nonprofits in South Carolina?


Read more about each grant below or start your 14-day free trial to see all unrestricted grants for nonprofits in South Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Unrestricted Grants for Nonprofits in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Unrestricted grants for nonprofits in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Unrestricted grants for nonprofits in South Carolina over $25K in average grant size

40 Unrestricted grants for nonprofits in South Carolina over $50K in average grant size

32 Unrestricted grants for nonprofits in South Carolina supporting general operating expenses

100+ Unrestricted grants for nonprofits in South Carolina supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Unrestricted grants for Nonprofits in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
25.2%
Q3
24.8%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Unrestricted Grants for Nonprofits in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$535,356 $535.4 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Unrestricted Grants for Nonprofits in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Unrestricted Grants for Nonprofits in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Unrestricted Grants for Nonprofits in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081