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Best Unrestricted Grants for Nonprofits in South Carolina

Find the perfect Unrestricted grants for nonprofits in South Carolina on Instrumentl. 9,000+ Unrestricted grants for nonprofits in South Carolina in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,267 Results based on applied filters

Lily Smith Memorial Scholarship

Central Kentucky Community Foundation
Private
United States
Unspecified amount
The Lily Smith Memorial Scholarship, established by the Central Kentucky Community Foundation, supports high school graduates from Nelson County pursuing a nursing degree. Founded in 1960, the foundation is committed to enhancing community well-being through philanthropy. This scholarship exemplifies their mission by providing financial assistance to future nurses, ensuring that local talent is nurtured and prepared to meet healthcare needs. The initiative reflects a deep commitment to education and community service.
Education - Higher Education Nursing Education - High School +1 more

Tribal Maternal, Infant, and Early Childhood Home Visiting Program: Development and Implementation Grants (363222)

US Dept. of Health & Human Services: Administration for Children & Families
Federal Government
United States
US $250,000 - US $1,000,000
The Tribal Maternal, Infant, and Early Childhood Home Visiting Program seeks applications for Development and Implementation Grants to support evidence-based home visiting programs for expectant families and young children. Funded by the U.S. Department of Health & Human Services, these grants aim to enhance maternal and child health, improve parenting practices, and foster early childhood development within tribal communities, ultimately promoting better socio-economic outcomes and reducing instances of child maltreatment.
Maternal And Perinatal Health Child Welfare Services Early Childhood Development

Daniel W. Schindlbeck Memorial Scholarship Endowment Fund

Community Foundation of the Fox River Valley
Private
United States
Unspecified amount
The Daniel W. Schindlbeck Memorial Scholarship Endowment Fund, established in 2004, provides scholarships for students pursuing careers in criminal justice or law enforcement. Funded by the Community Foundation of the Fox River Valley, it honors Daniel Schindlbeck, a dedicated police officer in Aurora. The typical award is $1,000, supporting students from the foundation's service area, including Kane and Kendall counties. This initiative promotes education and community service, ensuring a lasting legacy of civic engagement.
Education - Higher Education Career / College Preparation Education - High School +1 more

Zonta Club of Greater Sandusky Nontraditional Students Scholarship Fund

Erie County Community Foundation
Private
United States
Unspecified amount
The Zonta Club of Greater Sandusky offers a scholarship fund aimed at supporting female residents of Erie, Huron, Ottawa, or Sandusky Counties, Ohio. This fund is specifically for women aged 23 and older who are returning to education after a break. Eligible candidates must be enrolled in a 2-4 year undergraduate program at an accredited institution, empowering them to enhance their educational and professional prospects.
Education - Higher Education Women & Girl Services Education - High School +2 more

AISES Burlington Northern Santa Fe (BNSF) Foundation Scholarship

American Indian Science and Engineering Society (AISES)
Association/Society
United States
US $2,500
The AISES Burlington Northern Santa Fe Foundation Scholarship supports Native students pursuing degrees in STEM fields. This scholarship aims to empower Indigenous students by providing financial aid and fostering diversity within the STEM community. Applicants must be full-time students and either enrolled citizens or descendants of recognized Native American or Indigenous groups. The program is part of BNSF’s commitment to enhancing educational opportunities for underrepresented communities in the transportation sector.
College Success / Persistence STEM / STEAM Education Academic Scholarship Programs +1 more

The Manzer-Keener-Wefler Scholarship Fund

Stark Community Foundation
Private
United States
More than US $500

Stark Community Foundation

Since 1963, Stark Community Foundation has been helping individuals, families, businesses and nonprofits like you support the causes you care about.

In addition to personalized donor services, we manage a competitive grantmaking program and award grants to address local needs. Today, the Foundation stewards over 1,000 charitable funds totaling $485 million in assets and has granted more than $300 million to nonprofits in our community and beyond.

Scholarships

Stark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.

The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties.

The Manzer-Keener-Wefler Scholarship Fund

The Manzer-Keener-Wefler Scholarship Fund assists applicants with a field of study in or related to photography, visual arts (including graphic design). 

This scholarship is renewable.

Education - Higher Education Visual Arts Design +1 more

Jerry J. Murphy MSW Scholarship Fund

Community Foundation of the Fox River Valley
Private
United States
Unspecified amount

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Jerry J. Murphy MSW Scholarship Fund

The Jerry J. Murphy MSW Scholarship Fund provides scholarships to students pursuing a Master of Social Work degree.

Jerry Murphy is the retired Executive Director of the INC Board. He served residents of Kane County for over 28 years during his time with the organization.

INC Board, NFP, is an Illinois, not-for-profit corporation which was chartered as Mental Health and Mental Retardation Services on April 21, 1969, to promote the creation of local mental health boards authorized under 405 Illinois Compiled Statutes §20/3a.

Education - Higher Education Career / College Preparation Education - High School +1 more

Olsson Roofing Company, Inc. Scholarship Fund

Community Foundation of the Fox River Valley
Private
United States
Unspecified amount

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Olsson Roofing Company, Inc. Scholarship Fund

In 1988, Olsson Roofing Company, Inc. of Aurora created a scholarship fund within the Community Foundation for area students.

Scholarships from this fund are awarded in recognition of high scholastic achievement, participation in school activities and leadership potential.

These awards are reserved for students whose parents are actively involved in the roofing trade or construction industry.

Through the generosity and commitment of this civic-minded company, many students have received needed assistance for their college educations.

Education - Higher Education Career / College Preparation Education - High School +1 more

The James V. Gray Memorial Scholarship II

Erie Community Foundation
Private
United States
Unspecified amount
The James V. Gray Memorial Scholarship II, awarded by the Erie Community Foundation, supports Erie County graduating seniors pursuing two-year programs with a minimum GPA of 2.5. In 2023, the foundation awarded over $800,000 in scholarships to help over 500 students achieve their educational dreams. This need-based scholarship honors James Vincent Gray, a dedicated teacher and coach, reflecting the foundation's commitment to education and community development.
Education - Higher Education Career / College Preparation Academic Scholarship Programs +1 more

The Sophie Kosiorek Scholarship

Erie Community Foundation
Private
United States
Unspecified amount
The Sophie Kosiorek Scholarship, provided by the Erie Community Foundation, awards $800,000 in scholarships to over 500 deserving students annually. This scholarship specifically supports a four-year member of the Seneca High School girls basketball team, recognizing the positive attitude and strong team ethic exemplified by Sophie. Eligible applicants must maintain a GPA of 3.0 or higher, ensuring that the scholarship supports both athletic and academic excellence.
Career / College Preparation Academic Scholarship Programs Education - Higher Education +1 more

OJJDP FY 2026 Strategies to Support Children Exposed to Violence

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
Up to US $815,000
The OJJDP FY 2026 Strategies to Support Children Exposed to Violence program aims to implement effective violence reduction strategies targeting juvenile offenders. This initiative focuses on enhancing community capabilities to assist children affected by violence in various environments, including homes and schools. By strengthening local responses to child victimization, the program seeks to diminish the incidence of violence and alleviate the long-term adverse effects that such exposure can have on children's well-being.
Mental Health & Psychiatric Diseases Youth Services Crime & Justice +2 more

Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required) (363926)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Neurological Disorders and Stroke (NINDS) aims to enhance research on Amyotrophic Lateral Sclerosis (ALS) through intermediate patient population expanded access protocols. These protocols will provide investigational drugs to ALS patients while collecting vital data to inform future treatments and care strategies. This initiative seeks to better understand the disease's biomarkers, patient experiences, and the overall impact of investigational therapies, fostering advancements in ALS research and care.
Neurological Diseases & Disorders Stroke Amyotrophic Lateral Sclerosis (ALS)

Health Equity and Inclusiveness Research Fellow Award

LUNGevity Foundation Inc
Private
United States
US $50,000 - US $100,000
The Health Equity and Inclusiveness Research Fellow Award by LUNGevity supports physician-scientists conducting lung cancer research aimed at addressing health disparities. Funded projects will focus on early detection and improved outcomes for lung cancer, particularly among underserved communities. Awards can reach up to $100,000 over two years, with payments contingent on project milestones. This initiative aims to foster innovative research and enhance individualized treatment approaches for lung cancer.
Lung Cancer Health Disparities & Social Determinants of Health

State Maternal Health Innovation Program (SMHI)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
US $657,142 - US $1,000,000
The State Maternal Health Innovation Program (SMHI) aims to enhance maternal health across states by addressing critical gaps. It focuses on improving service quality, developing a skilled workforce, and utilizing enhanced data capabilities. Through innovative programming, the initiative strives to significantly reduce maternal mortality and severe maternal morbidity, ensuring better health outcomes for mothers and their families.
Women's Health Maternal And Perinatal Health

Dr. Dianna K. Wolfe Memorial Scholarship

Community Foundation of Randolph County
Private
United States
Unspecified amount

About Us

We are YOUR Community Foundation! Our mission is to bring people and resources together to strengthen the quality of life, both now and in the future, for the residents of Randolph County.

The Community Foundation of Randolph County, Inc. is here to make our community the very best place to live, work, and raise a family. As a non-political private organization, we are uniquely able to provide grant money for innovative projects that have a major impact on our community.

Dr. Dianna K. Wolfe Memorial Scholarship

Dr. Dianna K. Wolfe was a lifelong resident of Winchester. After graduating from Lee Driver High School at the age of 17, she started Nurses Training at Ball Memorial Hospital School of Nursing, where she received her nursing degree. She earned her bachelor’s degree in nursing from Indiana University. She also earned her master’s degree and her doctorate degree from Ball State University. She joined the Ball State University School of Nursing faculty in 1977, teaching in the associate, baccalaureate, and graduate nursing programs for about 33 years, where she maintained her professional clinical practice as an evening supervisor. During her career she was flexible, adaptable, and willing to try new teaching strategies as technology progressed, and her students gave her high ratings throughout her tenure as being well organized and relating course materials effectively.

During that time, she raised six children. Her love of education inspired her husband, Robert, to go to school and he subsequently earned two degrees.

In creating the Dr. Dianna K. Wolfe Memorial Scholarship, her family hopes to continue her legacy by assisting students interested in obtaining education to work in the healthcare field.

Education - Higher Education Nursing Career / College Preparation +1 more

Maternal and Child Health (MCH) Nutrition Training Program (363411)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +7 more
US $550,000 - US $735,000
The Maternal and Child Health (MCH) Nutrition Training Program aims to enhance the nutrition and overall health of mothers and children. This initiative focuses on interdisciplinary graduate education, equipping a skilled workforce to support Title V and other MCH programs. It seeks to expand nutrition education and career pathways while improving access to quality nutrition services. Trainees will gain practical experience through placements at health centers, ultimately benefiting families and communities.
Maternal And Perinatal Health Nutrition & Healthy Eating

NIHCM Foundation: Trade Journalism Award

The National Institute for Health Care Management
Private
United States
US $15,000
The NIHCM Foundation's Trade Journalism Award honors outstanding reporting aimed at specialty audiences, focusing on enhancing the affordability, accessibility, and quality of healthcare in the U.S. A $15,000 prize will be awarded to the winner. Entries, which can be individual stories or series published in 2025, must provide valuable insights relevant to health plans, policymakers, and stakeholders, addressing the critical issues of rising healthcare costs and access.
Journalism Health Care Access & Delivery Health Policy & Advocacy +1 more

AVID: Priscilla and Ranney Draper Scholars Fund

Scholarship America Inc
Private
United States
US $5,000
The AVID: Priscilla and Ranney Draper Scholars Fund offers scholarships to high school seniors enrolled in the AVID elective, supporting their transition to a four-year college or university. Administered by Scholarship America, this program recognizes students from Orange County, CA, who have demonstrated commitment and financial need. Each applicant completes a single application for multiple scholarships, with awards of up to $5,000 available for undergraduate studies.
Education - Higher Education Academic Scholarship Programs College Success / Persistence +1 more

First Solar Community Giving Fund

South Carolina Native Plant Society Grand Strand Chapter
Association/Society
Florence County, South Carolina, Georgetown County, South Carolina +3 more
Up to US $1,500
The First Solar Community Giving Fund, managed by the Grand Strand Chapter of the South Carolina Native Plant Society, supports local projects focused on native plants. This nonprofit organization, based in Conway, offers grants up to $1,500 to encourage community involvement in conservation efforts. The Grand Strand Chapter aims to fund 3 to 4 projects that align with its mission of protecting and educating about native plant species.
Botanical Conservation Habitat & Ecosystem Restoration

John W. Burandt Scholarship

Rochester Area Community Foundation
Private
United States
US $2,000

Mission & Vision

Rochester Area Community Foundation, in partnership with generous philanthropists and community partners, works to improve the quality of life for people who live and work in the eight-county region through its leadership and strategic grantmaking.

Our Mission:

We are cultivating a thriving Greater Rochester region — powered by philanthropy, grounded in community, and sustained across generations.

Our Vision:

We envision a Greater Rochester region transformed by enduring philanthropy, where every person, neighborhood, and future generation can thrive.

John W. Burandt Scholarship

Purpose of Scholarship

To provide support for tuition, fees, books, and other expenses associated with post-secondary education for dependents of firefighters residing in the city of Rochester, NY.

Number and Size of Awards

One award of $2,000; paid in the Fall and and divided equally between the Fall and Spring semesters.

Donor Information

This scholarship was established by Mrs. Lorene (Rene) Burandt in honor of her husband, John W. Burandt, a dedicated firefighter who served the Rochester community for 30 years.

Firefighting & Fire Prevention Vocational & Trade Education Educational Access & Equity +1 more

The Woman’s National Farm and Garden Association (WNF&GA) Scholarship for the Study of Conservation and Natural Resources Management

Woman's National Farm and Garden Association, Inc.
Association/Society
United States
US $4,000
The Woman's National Farm and Garden Association (WNF&GA) Scholarship supports graduate students pursuing careers in conservation and natural resource management. This annual scholarship aims to continue the legacy of conservationists dedicated to protecting our planet's resources. Eligible candidates must demonstrate a strong commitment to environmental stewardship through their academic and community involvement. However, WNF&GA members and their immediate families are excluded from eligibility. The scholarship is a vital resource for future leaders in conservation.
Environmental Conservation Natural Resources

Animal and Veterinary Innovation Centers (U18)

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
American Samoa, Guam +4 more
Up to US $7,500,000
The Animal and Veterinary Innovation Centers (U18) funding opportunity, led by the FDA, aims to foster collaborations with academic institutions to tackle critical veterinary health challenges. This includes addressing Highly Pathogenic Avian Influenza, promoting genomic advancements in agriculture, and developing veterinary solutions for minor species. Applications are invited to enhance animal health and public safety, with Letters of Intent due prior to the July 2024 deadline.
Genetics & Genomics Epidemiology & Public Health Veterinary Science & Services +2 more

Disaster Grants Program

Legal Services Corporation
Private
United States
Unspecified amount
The Disaster Grants Program by LSC provides vital funding to organizations aiding survivors of government-declared emergencies. It empowers legal aid groups to deliver essential services to low-income disaster survivors, ensuring access to legal assistance during crises. The program also educates communities on disaster legal services and prepares them for future emergencies, enhancing resilience and response capabilities. By supporting various grant types, the initiative addresses immediate needs and fosters long-term recovery strategies.
Disaster Relief / Humanitarian Aid Legal Services Supportive Housing & Shelters

Samuel "Eric" Storm Memorial Scholarship Fund

Community Foundation For Mississippi
Private
United States
US $2,500
The Samuel "Eric" Storm Memorial Scholarship Fund offers $2,500 to students pursuing advanced degrees in Physical Therapy, Occupational Therapy, or Speech Therapy. Established in honor of Eric Storm, a dedicated physical therapist, the fund aims to support students in accredited programs. Eric's legacy includes his commitment to mentorship and community service, reflecting his belief in health care as a calling. This scholarship honors his impact on many lives and encourages future health professionals to follow in his footsteps.
Education - Higher Education Academic Scholarship Programs Physical Therapy +2 more

Patient Reported Outcomes (PROs) RFP

Arthritis Foundation
Private
United States
Up to US $235,000
The Arthritis Foundation is seeking research proposals focused on Patient Reported Outcomes (PROs) to enhance shared decision-making in arthritis care. Projects should aim to deepen the understanding of patient treatment goals, monitor disease activity, and improve communication of PRO data. Research can span various arthritis types, including osteoarthritis and rheumatoid arthritis, and should last up to two years. This initiative emphasizes the integration of patient perspectives to elevate care quality.
Musculoskeletal Diseases Arthritis

ATS/PHA Early Career Award

American Thoracic Society Inc
Association/Society
United States
Up to US $50,000

ATS/PHA Early Career Award

One grant is available for early-career investigators interested in pulmonary hypertension research who are likely to make a strong and sustained impact in PH research. This grant is co-funded by the Pulmonary Hypertension Association and ATS.

Areas of interest for proposals include:

  • Investigating the pathophysiology of PH
  • Elucidating mechanistic pathways
  • Identifying novel therapeutic targets or biomarkers in adult or pediatric pulmonary hypertension

The project should have potential applicability to human pulmonary vascular diseases.

Applicants may request up to $50,000 for one year for salaries or supplies or a combination thereof.

Cardiovascular Diseases & Systems Chronic Obstructive Pulmonary Disease

Scholarships for Non-Tribal College Students

American Indian College Fund
Private
United States
US $2,000 - US $3,000
The American Indian College Fund offers scholarships for non-Tribal college students, providing financial support for American Indian and Alaska Native students pursuing higher education at accredited institutions. Applications open annually on February 1st, with a priority deadline of May 31st. Award amounts typically range from $2,000 to $3,000. Students are encouraged to apply early to ensure priority review for available scholarships, fostering educational opportunities and success for Indigenous youth.
Native American Services Native American Culture & Heritage Indigenous Services

Unrestricted Grants for Nonprofits in South Carolina Highlights

Looking for unrestricted grants for nonprofits in South Carolina?


Read more about each grant below or start your 14-day free trial to see all unrestricted grants for nonprofits in South Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Unrestricted Grants for Nonprofits in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Unrestricted grants for nonprofits in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Unrestricted grants for nonprofits in South Carolina over $25K in average grant size

40 Unrestricted grants for nonprofits in South Carolina over $50K in average grant size

32 Unrestricted grants for nonprofits in South Carolina supporting general operating expenses

100+ Unrestricted grants for nonprofits in South Carolina supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Unrestricted grants for Nonprofits in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
25.2%
Q3
24.8%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Unrestricted Grants for Nonprofits in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$535,356 $535.4 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Unrestricted Grants for Nonprofits in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Unrestricted Grants for Nonprofits in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Unrestricted Grants for Nonprofits in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081