Best Grants for 501(c)(3) in South Dakota

The MRC/SOT Early Career Toxicologist Award, presented by the Society of Toxicology, recognizes an outstanding Midwest toxicologist with up to 10 years of experience. This prestigious award honors candidates actively contributing to the field or recently retired, showcasing their unique research achievements and teaching proficiency. Winners receive an engraved plaque and an honorarium, celebrating their commitment to advancing toxicology and enhancing human, animal, and environmental health.

The NRP Research Grant Program offers up to $50,000 for healthcare professionals to explore optimal neonatal resuscitation methods. It encourages innovative research addressing gaps in transitional physiology and effective teaching of resuscitation skills. Applications must focus on evidence-based practices and demonstrate potential for meaningful impact in delivery room care. Researchers from Canadian and US institutions are eligible, though applications primarily focused on quality improvement without a research emphasis will not be considered.

The Tobacco Youth & Community Engagement RFA (SD) aims to empower youth and their communities to combat tobacco use, including e-cigarettes. This initiative supports evidence-based prevention and cessation strategies tailored for individuals under 24 years old. Funded by the South Dakota Department of Health, this grant provides between $5,000 and $25,000 to applicants dedicated to fostering healthy environments and reducing tobacco-related harm among young populations.

The North Central Branch John Henry Comstock Award recognizes one graduate student from each of the Entomological Society of America's six branches. This award promotes graduate-level entomology and encourages attendance at the ESA Annual Meeting. Benefits include an all-expense-paid trip to the national meeting, a $500 cash prize, and a certificate presented during the meeting. Eligibility includes current enrollment in a graduate entomology program or recent graduation.

Entergy’s Open Grants Program aims to enhance community well-being through funding initiatives in arts, education, social services, and community improvement. The program prioritizes support for organizations that serve diverse populations, including children and low-income communities. Eligible entities must have 501(c)(3) status or equivalent nonprofit recognition. Applications should be submitted three months in advance, allowing ample time for review. Entergy focuses on projects that foster self-sufficiency and enrich local neighborhoods.

South Dakota Community Foundation

As a statewide community foundation, we work with donors, nonprofits and community leaders to strengthen philanthropy in South Dakota every day.

Scholarships

At South Dakota Community Foundation (SDCF), we proudly manage more than 350 scholarship funds in partnership with generous donors who are committed to supporting students. These scholarships offer countless opportunities to help ease the financial burden of continuing their education.

Mansour Karim Scholarship

To provide financial support for nursing students attending Capital University Center in Pierre, SD.

The Touring Arts Sponsor Grant Program, managed by the South Dakota Arts Council, aims to enhance the accessibility of quality arts programming across schools and communities in South Dakota. This initiative provides matching funds up to 50% of the program costs to eligible nonprofit organizations and educational institutions. It fosters cultural enrichment by facilitating diverse artistic engagements, ensuring that the arts are available in every region of the state.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5430 - Unlocking Value and Opportunities from Carbon Flows in Water Utilities

Grant Information

• Identify carbon flows across drinking water, stormwater, wastewater, and advanced treatment systems. Carbon flows may include source water, stormwater, process emissions, process inputs, residuals, and biogas.
• Identify the most relevant carbon recovery, capture, conversion, storage, and avoidance opportunities.
• Evaluate value creation pathways, including products, avoided costs, and environmental attributes, and mechanisms and partnerships needed to put them into practice.
• Assess how opportunities vary across system types and local contexts by focusing on more common scenarios for utilities.
• Provide practical, research-based insights to support identification, prioritization, evaluation, and advancement of carbon management opportunities under site-specific conditions and constraints.
• Evaluate implications for greenhouse gas (GHG) accounting, environmental attribute claims, and other potential benefits across pathways.

The LFF: Nature-Based Climate Action Grant aims to support initiatives that leverage natural systems to combat climate change. By funding projects focused on tree planting, prairie restoration, and carbon sequestration, the program seeks to engage communities and enhance understanding of climate challenges. Ideal applicants include rural organizations working to create measurable environmental impacts while fostering collaboration and policy change. This grant represents an opportunity for organizations ready to take significant strides in addressing the climate crisis.

The Mazamas is committed to exploring and preserving mountain environments in the Pacific Northwest through research grants. These grants support nonprofit research that aligns with the Mazamas’ mission, encouraging proposals from graduate and undergraduate students. Successful applicants often conduct field studies that enhance understanding of the region's natural features. Notably, the Mazamas also welcome innovative research ideas that may fall outside traditional grant guidelines, promoting a diverse range of scientific inquiry.

The Asian Cultural Council's New York Fellowship offers a transformative six-month program for artists, scholars, and arts professionals from Asia. Participants engage deeply with New York City's vibrant cultural landscape, attending performances, exhibitions, and workshops while building networks with local communities. This unique opportunity fosters peer-learning and individual artistic development, encouraging fellows to incorporate their experiences into their practices and contribute to their home cultures. The fellowship emphasizes exploration, exchange, and support, culminating in a rich cultural immersion.

About Us

We come to work every day because we believe in the power of possibility.

We believe the Sioux Falls area is a great place to live, work, and play. We also believe we have a responsibility to help preserve and sustain what’s good here, and to champion ideas and movements that have the potential to make our community even better.

We believe that meaningful and important social impact comes from thinking outside the box and having the courage to dream big dreams.

We believe strongly in the power and purpose of philanthropy. To us, philanthropy is more than just gifts and grants — philanthropy is thinking about how we can leverage financial, intellectual and human capital to help create a stronger, more vibrant community.

Finally, we believe philanthropy challenges us all to consider two important questions about our future – questions that drive and inspire our work every day: If we don't join together to build a better tomorrow, who will? And if not now, when?

Supporting Area Students

We’re proud to award more than 70 competitive scholarships to deserving students each year. 

Whether you’re preparing to graduate from high school, wrapping up a general equivalency diploma, or working toward your undergraduate or graduate degree, the Sioux Falls Area Community Foundation is proud to partner with passionate donors to administer a wide variety of competitive scholarships to help you achieve your educational goals.

Siouxland Chapter CFMA Scholarship

Awarded to graduating seniors of high schools in South Dakota.

The Asian Cultural Council's Individual Fellowship provides artists, scholars, and arts professionals from Asia and the United States with opportunities for self-directed cultural exchange and research in unfamiliar regions. This program supports activities such as interviews, workshops, and archival research, fostering cultural immersion and collaboration. With a funding limit of $35,000, the fellowship encourages innovative proposals that enhance creative perspectives and relationships among peers, while also ensuring strong eligibility criteria for applicants.

The ReFED Catalytic Grant Fund, managed by Refed Inc., supports innovative solutions to minimize food waste and reduce methane emissions, a cost-effective strategy for climate action. This fund prioritizes initiatives that enhance food recycling and improve supply chain efficiency in the beef and dairy sectors. By focusing on proven methods, the grant aims to accelerate impactful changes in the food system, ultimately fostering sustainable practices and collaborative efforts to combat food waste.

The Anderson-Rogers Foundation Grant supports U.S.-based 501(c)(3) organizations focused on environmental protection, animal welfare, climate change mitigation, and social support. Established in 2001, this family foundation prioritizes innovative projects and general operating support for small organizations facing financial constraints. Note that applicants must first submit a letter of inquiry, as the foundation does not fund scholarships or grants to individuals or religious organizations, nor does it support organizations outside the U.S.

The Alan Peterson Agricultural Scholarship, offered by CommunityGiving, aims to support Minnesota residents pursuing agricultural studies at accredited universities. This scholarship respects natural resources, promotes innovation in agriculture, and encourages research while advocating for the agricultural sector at all levels. Eligible applicants must be entering their junior or senior year in a four-year college, with no GPA requirement. The program seeks to empower future leaders in agriculture and foster community engagement.

The South Dakota Department of Health offers Civil Money Penalty (CMP) funds to enhance the quality of life for nursing home residents. These funds are derived from penalties imposed on facilities not meeting Medicare and Medicaid standards. Eligible projects include support for residents during facility closures, relocation assistance, and initiatives that promote resident and family engagement in care quality. The program aims to reinvest CMP revenues to benefit vulnerable populations in the state.

South Dakota Department of Health

The South Dakota Department of Health (SD DOH) strives to promote, protect, and improve the health of all South Dakotans with information, licensing, and more.

Cardiovascular Disease Prevention and Treatment Funding

The South Dakota Department of Health is pleased to announce a funding opportunity, the Cardiovascular Disease Prevention and Treatment funding. This funding opportunity is intended to support strategies that have a focus on prevention, treatment and/or management of cardiovascular disease. The facilities awarded funding through this opportunity will receive funds and technical assistance to create and expand sustainable programs to help link resources that support self-management and lifestyle changes to address those at increased risk for CVD with a focus on hypertension management.

The South Dakota Department of Health (SD DOH) Heart Disease and Stroke Prevention Program (HDSPP) is offering funding to meet one or both of the following priorities: Priority 1: Self-Measured Blood Pressure (SMBP) Program; and Priority 2: Care Coordination Program.

Priority 1: Self-Measured Blood pressure (SMBP) Program

Self-Measured Blood Pressure (SMBP) Program supports the implementation and expansion of Self-Measured Blood Pressure Monitoring programs through partnerships with local healthcare facilities and clinics. These programs are designed to help individuals with hypertension manage their condition effectively by monitoring their blood pressure at home in conjunction with clinical support.

The Waste Management Charitable Contributions Program supports initiatives that enhance environmental stewardship, sustainability education, and community vitality. With a commitment to civic pride and economic development, the program prioritizes organizations that address local needs and promote sustainable practices. Eligible applicants include 501(c)(3) organizations that focus on public purposes, while ineligible requests include funding for operating costs and individual fundraising events. This initiative fosters a collaborative approach to community betterment.

Community Finance Initiative 

Advancing the financial resilience of low-income households across the U.S.

This model enables us to engage and support a broad range of organizations across the globe to tackle some of the most pressing social issues of our time.

The Citi Foundation’s 2026 Community Finance Initiative commits $35 million to support programming that bolsters the financial stability, strength and safety of low-income households in the U.S.

Focus Areas

The Foundation seeks to support organizations advancing low-income household financial resilience in the United States across three focus areas:

Stabilize: Programs that help low-income households to build financial skills and confidence to manage daily finances and navigate financial stress.

• Financial coaching on budgeting, credit, debt reduction and savings strategies.
• Digital tools offering personalized financial guidance and product navigation.
• Assistance with public benefits and social safety net programs.

Strengthen: Programs that help low-income households build and repair credit, as well as short- and long-term financial assets.

• Financial products or services for credit building and credit repair.
• Initiatives to increase savings, including emergency funds.
• Support for homeownership, including readiness, preservation and long-term stability (e.g., first-time buyer assistance, preventing displacement and support systems for aging in place resources).

Safeguard: Programs that protect low-income household financial security by preventing and addressing financial losses.

• Education and support for the safe and confident use of digital financial tools.
• Fraud and scam awareness, prevention and recovery initiatives, including protection from identity theft.
• Interventions to help households recover from major financial shocks (e.g., healthcare costs, extended family care, job transitions or natural disasters).

Funding Opportunity

The Foundation plans to award 70 $500,000 (USD) grants (to be disbursed over two years) totaling $35 million to community organizations working in select communities where Citi has a presence.

The grants will be restricted and are anticipated to be disbursed in two annual payments in 2026 and 2027. Proposed projects should be for a term of 24 months, starting no sooner than August 1, 2026 and ending no later than December 31, 2028.

The Tobacco Prevention & Cessation RFA aims to support community-driven initiatives that promote tobacco-free lifestyles in South Dakota. With a focus on collaboration among local organizations, this funding opportunity seeks to implement strategies outlined in the SD-TCP State Plan, which emphasizes long-term changes to reduce tobacco-related health issues. By fostering partnerships and investing in impactful projects, the RFA is dedicated to decreasing the prevalence of tobacco use and its associated harms in the state.

The Bush Prize: Native Nations honors Native-led organizations committed to innovative solutions in their communities. Grants can reach up to $500,000, covering 25% of the organization’s previous fiscal year expenses. This annual award emphasizes collaboration and resourcefulness, supporting entities that are deeply valued in their communities and have proven success in addressing challenges. The program, a partnership with four community grant partners, aims to empower organizations in Minnesota, North Dakota, South Dakota, and 23 Native Nations.

The CHS Foundation's Ag Leadership Grant aims to enhance agricultural leadership and cooperative education. This program supports projects that cultivate a diverse pipeline for future agricultural leaders, focusing on education and career training for high school students to young professionals. Priority is given to initiatives that impact multiple states within the CHS trade area, thereby fostering a deeper understanding of the cooperative business model in agriculture.

The Osmann Family Native American Scholarship supports South Dakota high school seniors who are enrolled members of a Native American tribe. Managed by the Sioux Falls Area Community Foundation, this scholarship is aimed at students planning to attend a four-year college or technical school in the state. Eligible candidates must maintain a minimum GPA of 2.5 and demonstrate commitment to academic success and community involvement. The scholarship is renewable for up to three additional years, providing crucial financial support for education.

Kimberly Rose Means — Native American Council of Tribes Scholarship

Awarded to a graduating senior who is an enrolled member of a South Dakota Native American tribe or a South Dakota tribal member who is returning to school. 

The Stimulating Hematology Investigation: New Endeavors (SHINE) program aims to enhance nonmalignant hematology research aligned with the goals of the NIDDK, NIA, and NHLBI. It invites R01 grant applications focused on innovative and early translational hematology topics, fostering growth in this critical research area. Key deadlines for applications span from February 2025 to October 2027, allowing for both standard and renewal submissions.

The Call for Kindness Grant, offered by Riley's Way Foundation, empowers young leaders aged 13-23 to launch impactful social projects focused on kindness and community connection. With grants up to $5,000, recipients receive essential mentorship, coaching, and community support. This initiative has already benefited over 3,500 youth nationwide, promoting values of empathy and social change. Applicants can pursue projects in diverse areas, including environmental justice, ensuring a broad impact in their communities.