Best Grants for Nonprofit Healthcare Programs in Missouri

Missouri 501(c)(3) nonprofits serving the greater Kansas City area can seek $150,000 - $500,000 for healthcare, social services, education, arts, and Jewish community initiatives that expand services or improve outcomes for low-income, underserved residents. Focused on transformational change, the Marion and Henry Bloch Family Foundation supports special programs, capacity building, and capital projects rather than general operations.

The Costco Wholesale Charitable Contributions program prioritizes support for children, education, and health services within local communities. Nonprofit organizations seeking assistance must be 501(c)(3) certified and focus on monetary requests. Applications are reviewed within 4-6 weeks, factoring in community needs and collaboration. However, Costco limits grants to 10% of the program budget and typically restricts organizations to one request per fiscal year. They do not fund individuals or direct aid for various specific purposes.

Nonprofit 501(c)(3) organizations serving youth through health, education, or welfare programs in Missouri and beyond can seek funding for direct services and enrichment initiatives. The Dan Paul Foundation supports child advocacy, homelessness, poverty relief, clean air and water, refugee enrichment, and related youth development efforts with grants up to US $15,000.

Nonprofit 501(c)(3) organizations in the greater Kansas City metro, including Missouri counties such as Jackson, Cass, Clay, and Platte, can apply for Hall Family Foundation’s grants to support community health, healthcare access, and related services. Programs in Missouri that advance equitable health, livable neighborhoods, and family well-being may be competitive.

U.S.-based 501(c)(3) cultural institutions with audited expenses over $2 million can apply for the Hearst Foundation’s culture grants to support arts and science programming, including in Missouri. Funding (often more than US $100,000) may support program, capital, or limited general/endowment needs, and health-related nonprofits with strong arts or STEM education components may be eligible.

The PNC Foundation aims to enhance the lives of individuals in local communities through partnerships with nonprofit organizations. Their focus includes promoting educational opportunities, particularly for early childhood education, and supporting economic development initiatives. Grants are available for organizations that benefit low- to moderate-income families and enhance community growth. The foundation prioritizes programs that foster sustainability and diversity, ensuring a lasting impact on the communities they serve.

The Sidney Stern Memorial Trust Grant supports charitable, scientific, medical, and educational organizations that are 501(c)(3) certified. This private funder emphasizes impactful service to diverse populations without discrimination. Grants must be utilized within the United States and cannot be awarded to individuals, political candidates, or lobbying efforts. The Trust is dedicated to enhancing the general welfare through soundly-managed initiatives that contribute significantly to community needs.

The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.

Nonprofit 501(c)(3) organizations running health and medical assistance programs in Missouri and other Southern states can seek project support that creates tangible, meaningful impact. Robinson Foundation supports healthcare access alongside poverty relief, children and families, disaster relief, veterans, and related services for communities below the Mason-Dixon line; single-year funding only, no capital projects.

The Dudley T. Dougherty Foundation Grant supports nonprofit charitable organizations recognized under section 501(c)(3) of the IRS Revenue Code. Established in 2002, the foundation aims to empower groups committed to positive change, fostering respect for life and the environment. Their vision emphasizes collaboration for a better future, encouraging applicants to embody these values in their initiatives. With a focus on impactful projects, this grant is an opportunity for organizations striving to make a critical difference in our world.

Nonprofit 501(c)(3) organizations, public schools, and qualified government entities can seek funding for education, environment, entrepreneurship, and community enrichment projects that benefit communities near Georgia-Pacific facilities, including in Missouri. Focused on broad community well-being, the Georgia-Pacific Foundation invites eligible groups within 30 miles of a GP manufacturing community to apply.

Nonprofit 501(c)(3) organizations in Missouri located within 15 miles of a TJX store, distribution center, or office can seek funding for basic needs, youth education, workforce readiness, and domestic violence safety programs. The TJX Foundation supports vulnerable families and children through community-based services rather than capital campaigns, salaries, or general operating funds.

Nonprofit health and human service organizations in the Kansas City region of Missouri can receive unrestricted, one-year support for mission-driven programs through United Way of Greater Kansas City’s Impact 100. Funding supports work in areas like health care access and delivery, behavioral health, housing, food security, and related education and financial stability services.

Nonprofit Partnership Grant ProgramJackson County, Missouri invites proposals from qualified non-profit organizations to receive competitive grant funding that directly serves and uplifts disadvantaged communities within the County. These funds are intended to support initiatives to promote equitable access to resources, improve quality of life, and address systemic disparities in areas such as housing, health, education, food insecurity, and community development.Jackson County recognizes that certain communities face historic and persistent barriers to opportunity. These barriers can stem from economic disinvestment, environmental hazards, limited access to healthcare, or systemic inequities in housing and employment. This grant program is designed to enable local organizations and agencies to address these challenges with innovative, impactful, and sustainable solutions.

Nonprofit 501(c)(3) organizations in Missouri addressing basic needs, community vitality, or volunteer-driven causes can apply for Ameriprise Community Grants to support hunger relief, shelter, economic development, arts access, and adult self-sufficiency programs. With a mission to strengthen communities, Ameriprise Financial provides U.S. nonprofits with funding that prioritizes measurable outcomes and Ameriprise employee or advisor volunteer engagement.

Nonprofit 501(c)(3) organizations addressing behavioral health and substance use disorders in Missouri and nationwide can apply for Elevance Health Foundation’s Behavioral Health Grant to expand treatment, prevention, and early intervention services. Grants support programs that increase access to MH/SUD treatment, reduce risks and harms, and lessen social isolation and loneliness among affected individuals.

Nonprofit 501(c)(3) organizations, school districts, and government entities supporting childcare for ages birth to five in rural Kansas or western Missouri can seek US $100,000 - US $500,000 to expand capacity, improve facilities, and increase affordability. Patterson Family Foundation supports projects serving its catchment communities; Missouri health-focused nonprofits offering childcare for working families may be eligible.

Missouri nonprofit healthcare programs, school districts, and government entities serving rural counties can access funding through the Patterson Family Foundation to develop, educate, license, recruit, or retain critical healthcare workers. Eligible organizations must operate within the foundation’s Kansas or western Missouri catchment and support thriving rural communities through healthcare workforce development initiatives.

Nonprofit 501(c)(3) organizations, school districts, and government entities expanding high school career and technical education programs in rural Missouri may be eligible for funding to modernize CTE offerings. With a mission to help rural communities thrive, Patterson Family Foundation supports projects that prepare students for high-demand industries and strengthen local workforces.

Missouri nonprofit 501(c)(3)s, school districts, and government entities improving rural education can access funding through the Patterson Family Foundation, with awards from US $25,000 - US $500,000. Projects in the foundation’s Kansas and western Missouri catchment that test new, potentially scalable ideas—especially project-based or experiential learning—may be eligible, including initiatives that strengthen rural health-related education pipelines.

Missouri nonprofit healthcare providers and other eligible 501(c)(3)s, school districts, and government entities can apply for Patterson Family Foundation’s Preventative Care Access Grant, awarding US $100,000 - US $500,000 to launch or expand care delivery models like telehealth, mobile health, and community paramedicine. Rural communities in the foundation’s Kansas and western Missouri catchment may benefit.

Nonprofit 501(c)(3) organizations, school districts, and government entities providing healthcare services in rural Kansas or western Missouri can apply for the Patterson Family Foundation’s Specialty Care Access Grant Program. Funding supports bringing specialty medical services—such as maternal care, oncology, dental, chronic disease, and mental or behavioral health—closer to rural communities, which may benefit Missouri nonprofit healthcare programs in eligible counties.

Nonprofit 501(c)(3) organizations, school districts, and government entities providing trades workforce training or upskilling can seek funding to support skilled trades, apprenticeships, and vocational education, including healthcare fields, in rural Missouri communities. Patterson Family Foundation supports projects serving its Kansas and western Missouri catchment, with potential multi-year support and limited capital and indirect cost funding.

Patterson Family Foundation

The Patterson Family Foundation, based in Kansas City, Missouri, is a family-led foundation that extends the legacy of Neal and Jeanne Patterson. The Foundation’s mission, “Working together to help rural communities thrive,” is carried forward through strategic grantmaking and other collaborative initiatives that serve rural counties across Kansas and western Missouri. 

At the Patterson Family Foundation, we believe that thriving rural communities aren’t just about the numbers—they’re about the people who choose to live there. A strong and engaged community is built on essentials like access to good jobs, quality healthcare, educational opportunities, and a sense of belonging. But keeping rural communities strong doesn’t happen on its own—it takes all of us working together. That’s why we focus on working with local leaders, businesses, and organizations to invest in the areas that matter most, ensuring that rural places don’t just get by but thrive for generations to come.

Community Needs Grant

We continue to invest in community-focused work through dedicated programs and initiatives that strengthen local leadership and support long-term community vitality. Our Community Engagement opportunities for the 2026 cycle are offered through targeted, collaborative efforts rather than an open call application process, allowing us to work closely with communities and organizations on high-impact, locally driven projects.

This opportunity supports projects that strengthen resident retention and encourage former residents to return by enhancing the spaces, services, and community assets that make rural places appealing to live, work, and build a future. Projects should help communities create environments where people feel connected, supported, and inspired to stay or come home. Applicants should plan to report on community participation, improvements to key spaces or assets, and early indicators of resident retention or increased engagement from returning residents. 

Nonprofit 501(c)(3) organizations and aligned for-profits in Missouri can receive more than US $50,000 to tell powerful stories about their work in preservation, education, or wellness. Jesse W Couch Charitable Foundation supports projects that highlight environmental conservation, mental health, early education, outdoor recreation, and related community programs, which may include nonprofit healthcare and wellness initiatives.

The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.

The Mutual of America Foundation Community Partnership Award honors exemplary nonprofit organizations in the U.S. that foster collaborative partnerships across sectors. Annually, a national competition showcases numerous organizations demonstrating impactful community partnerships. Six organizations receive recognition, including the Thomas J. Moran Award, which offers $100,000, and the Frances R. Hesselbein Award, granting $75,000. Since 1996, the award has acknowledged 262 partnerships, emphasizing Mutual of America's commitment to societal improvement through collaboration.