Best Large Grants for Nonprofit Organizations in Tennessee

The LAM Foundation offers Pilot and Feasibility Research Awards aimed at fostering innovative research in lymphangioleiomyomatosis (LAM). These awards support hypothesis-driven studies with the potential to advance understanding and treatment options for this rare disease. Applicants can request a maximum of $50,000 for a period of up to one year. The Foundation prioritizes new researchers, encouraging fresh perspectives in LAM research to enhance patient care and ultimately achieve a future without LAM.

The Combined Pilot Research Grants program, supported by the Plastic Surgery Foundation and various surgical organizations, aims to promote innovative research in hand and plastic surgery. With funding of up to $10,000 for one-year pilot projects, this initiative encourages the development of surgeon scientists and seeks to enhance research funding in the field. Eligible applicants must be medical professionals holding relevant positions in U.S. or Canadian institutions.

The Jordan Fund, established by John & Kelly Olerud in 2003, is dedicated to supporting children with special needs and their families. This grant-making organization assists children with substantial disabilities up to age twenty-one, covering costs for respite, therapy, and essential equipment not provided by insurance. By funding 501(c)(3) organizations, the Jordan Fund aims to enhance the quality of life for these children and their families.

PLTW Launch offers a rolling grant for schools across the U.S. to implement the PLTW Launch program for the upcoming academic year. All schools, especially those serving low-income and minority populations, are encouraged to apply. The grant covers participation and training fees, with requirements to implement multiple PLTW modules over time. This initiative aims to enhance STEM education, ensuring diverse access to innovative learning opportunities.

The Visionary Prize for Women’s Economic Empowerment, established in 2022 by Visionary Women and the Hostetler/Wrigley Foundation, honors a visionary woman leader of a nonprofit focused on advancing women's economic empowerment in the U.S. This prestigious award provides $100,000 in unrestricted funds to support the recipient's agency and its initiatives. Eligible candidates must have a minimum of four years of operation and an annual budget exceeding $500,000, actively working towards women's economic advancement.

Ryan Lesher Student Athlete Memorial Scholarship (NCF)

Provides scholarships to Council Rock South and North High Schools for students who participated in multiple sports and maintained a GPA over 3.0.

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

The Tim Moffatt Career Advancement Award

This scholarship will be awarded to deserving students who are graduating from a WCPS high school, or are a non-traditional learner with equivalent education, who have been accepted into a trade school/program/apprenticeship, or who have enlisted in the military. 

The Community Foundation of Hancock County offers educational support for Hancock County, Indiana adults who are seeking post-secondary training or schooling to improve their career prospects. There are also some opportunities provided by specific businesses in the area. The application is open year-round until all funds are used.

Adult Re-Education Fund

Established by John and Linda Zimmermann, this scholarship provides support to adults who wish to obtain additional education and/or training in order to increase employment opportunities.

Mission and Vision

The Mission of the Foundation is to improve the quality of life in the Coastal Bend by building community endowment and addressing social, educational, environmental, and cultural needs through the awarding of grants and scholarships.

The Foundation’s Vision is to provide the Coastal Bend with:

• Efficient gift options to meet donors’ charitable wishes
• Effective grants to charitable organizations and scholarships to students
• Ethical leadership to promote and enhance area philanthropy

Scholarships

The CBCF scholarship is open each year. Scholarships awarded will be for the following academic year. Scholarships are available only to students who graduated from a high school in one of the counties in the CBCF Service Area: Aransas, Bee, Jim Wells, Kleberg, Nueces, Refugio and San Patricio. Thanks to our generous donors, the Coastal Bend Community Foundation (CBCF) offers scholarships to students from over 100 funds.

Wilson - Chase Wilson Memorial 4-H Scholarship

Purpose

In memory of Chase Wilson, a former outstanding Nueces County 4-H member, who died in 1985 as a result of a tragic accident. Chase was a senior student at Texas A&M University in the College of Agriculture. He was due to graduate in the spring of 1985 with plans of a career ahead. The scholarship was established by his family to encourage 4-H members to continue their education beyond the high school level.

Jaden Lauderdale Memorial Scholarship

The Jaden Lauderdale Memorial Scholarship was established in 2017 by Doug and Jessica Lauderdale in memory of their daughter. Jaden was a 14 year old with a huge heart and always thought of others. She was waiting for a heart transplant at Riley. Her family wanted to continue Jaden's giving attitude by presenting an annual scholarship to one Greene County senior seeking a 2 or 4-year degree in the medical field.

The Community Foundation of Hancock County offers educational support for Hancock County, Indiana adults who are seeking post-secondary training or schooling to improve their career prospects. There are also some opportunities provided by specific businesses in the area. The application is open year-round until all funds are used.

Nancy King “Dare to Dream” Fund

The purpose of this fund is to honor the Greenfield Kiwanis Club, a group whose members were like family to Nancy, through the provision of scholarships to persons who wish to obtain additional education.

The Bernie Smillie Memorial Scholarship was established in 2010, in memory of Freeland resident and business owner Bernie Smillie. Bernie passed away in 2000, due to complications from a lung transplant he had received in 1994. In 2005, family and friends of Bernie established the Bernie Smillie Memorial Golf Outing. Proceeds of this outing has helped to promote organ donor support and awareness and establish this scholarship fund.

Bernie Smillie Memorial Scholarship - Medical

Evaluation Criteria

• Leadership ability
• Financial need
• Academic performance
• Standardized test scores
• Special skills
• Awards and honors
• Community service
• Work experience
• Extracurricular school activities
• Overall involvement
• Career goals as demonstrated in essay
• Letter of recommendation.

The National Cancer Institute (NCI) invites applications for the R33 grant aimed at advancing emerging technologies in cancer research. This funding opportunity seeks projects that demonstrate significant progress in technology development, focusing on cancer biology, early detection, and clinical diagnosis. Eligible proposals must showcase innovative methodologies that enhance research capabilities, with a strong emphasis on technical validation and broad applicability in cancer applications.

The National Meredith Willson Awards provide multi-year operating support to organizations using music for systemic change. The Music Man Foundation will award grants of $50,000 to $500,000 to 5-10 selected organizations in 2026, focusing on their impact through music. Eligible organizations must have 501(c)(3) status, a history of music programming, and a commitment to systemic change. Applications will be evaluated on leadership, organizational capacity, and alignment with grant criteria.

The Mount Rest Fund Grant, established by the East Tennessee Foundation, continues a legacy of support for women and children in Knox County. Founded in 2004, it honors the historical commitment of the Mount Rest Home, which began in 1894. The grant focuses on projects related to early childhood education, health drivers, and addressing Adverse Childhood Experiences (ACEs). Eligible organizations must serve the local community and comply with non-discrimination policies to qualify for funding.

The AGA Research Scholar Award offers $100,000 per year for three years to early-career faculty in digestive disease research. Applicants must hold an MD or PhD and be in a full-time faculty position in North America. The award fosters scientific independence by requiring a minimum of 50% research effort. AGA membership is mandatory, and applicants are encouraged to self-assign their proposals to specific research categories. This award aims to support promising junior researchers in their pursuit of independent research careers.

The Margaret M. and Harley H. Wachs Youth Leadership Fund Grant, established in 2001, aims to empower young people in Johnson County by providing travel and leadership opportunities. It focuses on engaging middle and high school youth in community service, leadership roles, and developmental travel. Eligible organizations include 501(c)(3) charities and educational institutions. Special consideration is given to programs that foster youth leadership in collaboration with community organizations. Grants will not fund religious projects or individual grants.

LaFrancine Stallings Math & Science College Scholars

The LaFrancine Stallings Math & Science College Scholarship will provide renewable need-based scholarships of up to $6,375 to undergraduate juniors enrolled full-time pursuing a Science Technology Engineering Mathematics (STEM) major at any four-year accredited HBCU in the 2026-2027 school year.

ASEEES Internship Grant Program

Funded by an external grant, ASEEES’s Internship Grant Program provides incoming, current, and recent (i.e. those who have graduated no more than two years prior to the competition deadline) MA, PhD, and professional school students with grants that make it possible for them to accept unpaid or underpaid internships in areas broadly related to Russia, including Russia’s relations with other regions/countries.

The grant offers $2,000 a month, to be paid directly to the grantee (intern) during their internship. In the case of underpaid internships, ASEEES will work with the host institutions and the grantees to make sure the grantee receives a combined stipend of $2,000 per month or has an extended duration for the internship.

The AGA Fellow Abstract Award, offered by the American Gastroenterological Association, provides a $500 travel award to MD, PhD, or equivalent fellows who present their abstracts at Digestive Disease Week® (DDW). The award encourages the participation of active trainee members and emphasizes diversity by inviting applications from underrepresented groups in biomedical research. The top abstract will earn an additional $1,000 award, highlighting excellence in gastroenterology research.

The World Childhood Foundation aims to eradicate child sexual abuse and exploitation through innovative programs. Organizations eligible for funding must be based in the U.S. and focus on child safety, supportive environments, and responses to abuse. The grant does not support emergency relief, orphanages, or established program costs. Interested applicants should start the process 1-2 months prior to the deadline to ensure they can fulfill the necessary requirements, including a site visit.

The AGA Pilot Research Award offers $40,000 for one year to independent investigators at any career stage, focusing on innovative research in gastroenterology or hepatology. Applicants must hold an MD, PhD, or equivalent degree, and AGA membership is required at the time of application. This award encourages early career researchers and supports projects with new directions, emphasizing mentorship for those in the early stages of their careers.

Saginaw Area Health Care Administrators Scholarship

The Saginaw Area Health Care Administrators Scholarship was established in 1987 to help advance health care for the elderly and ill elderly. The scholarship provides cash awards to assist employees of association members in meeting educational expenses. Each year, employees in the areas of administration, nursing, dietary, maintenance, and other health-related occupations are invited to apply for scholarships.

The Chaim Schwartz Foundation Grant supports initiatives that preserve and enrich Yiddish language, culture, theater, and art. Established in memory of Sandra Schwartz Tangri, the foundation aims to continue the rich social justice heritage of Yiddishkeit. Proposals can be project-specific or for general support, with grant amounts ranging from $500 to $5,000, and the application process is designed to be straightforward for non-profit organizations.

The Foundation for Physical Therapy Research aims to enhance public health through funding innovative research in physical therapy. With a mission to optimize movement and improve societal health, it supports both emerging and established researchers. By offering grants, scholarships, and fellowships, the Foundation has created a robust pipeline of skilled researchers. Their efforts also focus on addressing health disparities and advancing evidence-based practices, ensuring a brighter future for the profession and its impact on patient care.

The CATCH Grant, offered by USA Football, provides essential support to organizations facing critical challenges such as natural disasters or theft. This program aims to enhance the athlete experience by assisting with unexpected hardships affecting operations. Eligible organizations enrolled with USA Football can apply for varying award amounts based on their specific circumstances. For more information, refer to the FAQs available on the USA Football website.

The National Cancer Institute (NCI) invites applications for innovative technologies aimed at cancer research and clinical care. This funding opportunity supports early-stage projects focused on proof-of-concept studies to assess the feasibility of new methods and tools. Applications should demonstrate significant technical innovation, targeting advancements in cancer biology, early detection, clinical diagnosis, treatment, and epidemiology. Technologies may include novel analysis platforms, imaging technologies, and biospecimen processing innovations, with a focus on cancer applications.