Best Large Grants for Nonprofit Organizations in Tennessee

The Cat Enrichment Grant, offered by the Petfinder Foundation, provides funding ranging from $100 to $1000 to enhance the well-being of adoptable cats. Grants are awarded monthly until funds are depleted, supporting initiatives like interactive activities and safe outdoor experiences. This program aims to ensure that every cat remains happy and healthy while waiting for a forever home, ultimately increasing their chances of adoption.

The Office of Elementary and Secondary Education (OESE) is inviting applications for the Project SAFE Grant Program, aimed at enhancing student safety and well-being during the COVID-19 pandemic. This program provides essential resources to local educational agencies (LEAs) to implement effective strategies in accordance with CDC guidelines. Eligible applicants are encouraged to participate to ensure the health and safety of students across the nation.

The Farmers Advocating for Organic Grant (FAFO) supports impactful projects that enhance the organic agricultural sector, focusing on initiatives that assist family farmers and promote organic soil health. Eligible applicants include non-profit organizations and research institutions. FAFO prioritizes projects that address the needs of organic dairy, meat, and produce farmers while fostering cooperative growth. This grant aims to strengthen the organic industry and ensure the livelihood of organic farmers across the nation.

The Bigglesworth Family Foundation's Legal Services Program supports innovative projects aimed at enhancing legal aid effectiveness. Originating post-2008 financial crisis, this initiative helps non-profits combat poverty through legal assistance, targeting both individual organizations and the broader sector. Grants include I&R projects for testing new models and sector support for organizations providing technical assistance. Eligibility is primarily for 501(c)(3) nonprofits and public entities, with specific limitations on budget sizes and project types.

The Gerber Foundation provides research grants focused on pediatric nutrition, aiming to enhance the health and well-being of infants and young children. Key areas of interest include applied research on nutritional issues, benefits of specific nutrients, and innovative treatment regimens. The foundation prioritizes projects that promise significant advancements in health outcomes for children from birth to age three, ensuring that grant dollars effectively address critical development challenges.

The Miller Trust Grants, managed by EveryCat Health Foundation, support innovative feline health research. With a focus on projects that enhance knowledge of feline diseases and treatments, the grants offer up to $50,000 for 1-2 year projects. Eligible applicants include principal investigators from specific partner institutions. EveryCat has a rich history of funding over $11 million in research, promoting the health and well-being of cats globally. Proposals are welcomed in Spring and Fall grant cycles.

The Society of American Archivists Foundation Catalyst Grant provides funding ranging from $500 to $5,000 to support complex archival projects that advance the strategic goals of the SAA. This program prioritizes projects that foster best practices, such as processing and digitization of archives, and is open to non-profit archival repositories and individual archivists affiliated with member organizations. It aims to benefit the archival profession as a whole.

The Dog Field Trips/Short-Term Fostering Grant from the Petfinder Foundation aims to support organizations in purchasing essential supplies for short-term foster and dog field-trip programs. Grants ranging from $500 to $1000 are awarded monthly until funds are depleted. Eligible organizations must be Petfinder members in good standing, provide contact information, and submit a grant report post-funding. This initiative helps ensure that adoptable pets do not face euthanasia due to a lack of resources.

The Literacy Opportunity Fund, supported by the Nora Roberts Foundation and administered by ProLiteracy, provides grants ranging from $3,000 to $6,000 to nonprofit organizations in the U.S. that directly serve students with literacy programs. This initiative aims to enhance the operational capabilities of diverse literacy organizations, allowing them to effectively meet student needs. Applications are reviewed quarterly, ensuring timely support for eligible organizations that have not received funding within the calendar year.

The AEG K-14 Education Fund Grant supports geological education across K-14 levels, including elementary, middle, high schools, and community colleges. Established by the AEG Foundation, its purpose is to encourage innovative teaching methods in geology through hands-on activities and professional demonstrations. Grants are available to accredited educators and institutions in the U.S. While AEG membership is encouraged, it is not mandatory. The fund excludes support for political activities and overhead costs.

The Hemophilia Alliance Foundation's Impact Grants aim to support organizations enhancing services for individuals with inherited bleeding disorders. Since its inception in 2009, the foundation has awarded over $6.6 million, enabling innovative projects that expand capacity and collaboration. Eligible applicants include local organizations and federally-funded treatment centers, emphasizing creativity in project proposals. Priority will be given to initiatives that address unserved populations and foster educational advancements in the community.

The Kia Pet Adoption Grant, funded by the Petfinder Foundation as part of the Accelerate the Good program, supports organizations in the US, Canada, and Mexico with free or reduced-fee adoptions for dogs and cats. Grants are awarded monthly based on the number of adoptable pets listed on Petfinder.com until funds are depleted or November 1st. Grantees are required to report adoptions and share stories of pets adopted through this initiative.

The Senior Pet Adoption Assistance Grant, offered by the Petfinder Foundation, provides financial support to adopters of senior pets or bonded pairs. This initiative aims to encourage the adoption of older pets by covering costs such as adoption fees and post-adoption expenses, including veterinary care and supplies. Grants, up to $1,000, are awarded monthly until funds are depleted, ensuring that senior pets find loving homes while alleviating some financial burdens for their new families.

The Sports 4 Life Grants, co-founded by the Women’s Sports Foundation and ESPN, aim to promote the health and development of girls in underserved communities. This initiative focuses on increasing participation and retention rates of Black, Hispanic, and Native American girls in sports through funding for coaching, equipment, and facilities. By fostering leadership and self-esteem, the program seeks to empower young girls and provide them with lifelong benefits from sports participation.

The Sustainable Disaster-Relief Fund, established by Vanguard Charitable in 2006, aims to support communities affected by natural disasters. By providing funding for rebuilding efforts and necessary infrastructure, this initiative helps ensure that affected areas are better prepared for future disasters. Grants are available to 501(c)(3) organizations in good standing, focusing on charitable purposes like operating expenses and specific projects. The fund plays a critical role in enhancing community resilience and promoting effective disaster recovery.

The Hart Family Fund for Small Towns offers grants between $2,500 and $15,000 to support preservation projects in towns with populations of 10,000 or less. These funds aim to encourage local preservation efforts, enhance public discussion, and build technical expertise among community groups. The application process is competitive, with a review period of approximately three months. Eligible applicants include public agencies and nonprofits, with a cash match required. Projects must start within six months of receiving funding.

The Rachael Ray No-Kill Excellence Grants, funded by the Rachael Ray Foundation, support Best Friends Network partners in maintaining a 90% Save Rate for animals. These grants encourage innovative projects that enhance community partnerships and mentorships, helping organizations achieve sustainable lifesaving outcomes. Eligible organizations can apply for grants up to $60,000, with a focus on scalable programs that benefit animals and promote no-kill initiatives across the United States.

The National Institute on Aging intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the Coordinating Center (CC) of the Claude D. Pepper Older Americans Independence Centers (OAIC) program. The CC serves as a facilitator for OAIC site interactions and as a conduit for translating OAIC objectives and findings to both scientific and general audiences. The proposed CC must demonstrate an ability to work cooperatively with all OAIC sites and possess sufficient scientific expertise in geriatrics and related areas to serve the national coordination functions of the OAIC program. Applicants should have a demonstrated ability to coordinate multi-site projects.Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.

Takeda Oncology offers grant funding opportunities aimed at addressing unmet educational and research needs in the medical community. They prioritize support for programs in hematology, thoracic, and gastrointestinal cancers, including lymphoma, leukemia, and previously treated metastatic colorectal cancer. Takeda encourages partnerships that enhance patient outcomes and provide tangible benefits through donations, grants, and sponsorships. Applications must be submitted at least 60 days prior to the program start date for timely review.

The Overwatch Alliance Grants support non-profit organizations with annual revenues of $500,000 or less that aid military members, veterans, and their families. Grants of up to $15,000 are available for impactful projects such as emergency financial assistance, transitional housing, and employment support. Eligible organizations must be IRS-designated 501(c)(3) entities. The Alliance encourages applications from those addressing crucial veteran community needs while reinforcing the importance of community backing for capital projects.

Stealth Biotherapeutics offers grants and sponsorships aimed at enhancing healthcare education for providers and patient communities. These funding opportunities focus on innovative programs that address rare genetic disorders, neurodegenerative conditions, and ophthalmic disorders. To apply, requests must be submitted 60 days prior to the funding start date, ensuring alignment with the therapeutic interests of the organization while providing valuable insights for healthcare professionals.

Who We Are

The Unitarian Universalist Funding Program (UUFP) is a denominational grantmaking program of the Unitarian Universalist Association. Inspired by the richness and diversity of our liberal religious tradition, the mission of the UUFP is to promote the influence of Unitarian Universalist principles through grantmaking.

With funds generously provided by the Unitarian Universalist Veatch Program at Shelter Rock, the UUFP awards grants to Unitarian Universalist (UU) and non-UU projects and organizations. Grants are made that:

• Support the work of social justice.
• Strengthen Unitarian Universalist institutions.
• Transform gratitude for being into generosity of living.

Get Out The Vote - 2026

The Fund for UU Social Responsibility has increased funding for grants to UU congregations and organizations working to Get Out The Vote in 2026. Grants of up to $1,000 will be made on a rolling basis until funds are depleted.  

Please note that funds must go to a UU congregation or organization for the work by UUs of the organization. The funds may not be passed through to another organization. Collaboration and partnerships are encouraged.

UU congregations and organizations frequently support the democratic process in an election cycle in a non-partisan* manner by participating in voter registration drives, organizing to stop voter suppression, providing non-partisan educational materials or forums for voters, or by volunteering to help registered voters get to the polls on election day.

The Neighbor to Neighbor Disaster Relief Fund Grants, managed by the East Tennessee Foundation, focus on supporting nonprofits and agencies responding to the aftermath of Hurricane Helene in East Tennessee. This initiative aims to assist communities in recovery and rebuilding efforts, specifically targeting counties severely affected by flooding. Eligible organizations include public charities and educational institutions. The fund prioritizes long-term recovery efforts, fostering resilience and sustainability in impacted areas.

The Security and Preparedness (SAP) Program, supported by the National Science Foundation, promotes fundamental research addressing global and national security issues. It emphasizes intellectual merit and broader impacts, encouraging projects that are methodologically sound and empirically driven. Research areas include international relations, political violence, and peace science, among others. The program also fosters undergraduate research experiences and methodological innovations, while strictly avoiding applied research.

The PEN America: Phyllis Naylor Grant for Children’s and Young Adult Novelists awards $5,000 annually to authors of children's or young adult fiction. This grant supports writers at critical stages in their careers, specifically for a novel-in-progress. Candidates must have published works that received positive critical reception but limited sales. Self-published works and collaborative manuscripts are ineligible, ensuring that the grant focuses on authors with established literary merit.

The AHA: Rapid Response Funding offers crucial support to nonprofit organizations facing urgent campaign needs in the final stages of policy advocacy. This funding is intended for grassroots organizing, coalition building, polling, and media relations to successfully push for policy passage or defend against harmful legislation. Only organizations that are tax-exempt and have exhausted other resources are eligible, ensuring that funds are directed to campaigns with critical needs.

KaBOOM! Multi-Sport Courts provide innovative playspaces designed to meet the needs of older youth. These customizable sports courts allow communities to engage in various sports such as basketball and volleyball, addressing the lack of play opportunities. With guidance from KABOOM! Project Managers, applicants can fundraise and collaborate with community members to create an inviting space for active play, ensuring sustainable maintenance and ownership post-project completion.