Best Large Grants for Nonprofit Organizations in Tennessee

The JDF: FIRST LEGO League Explore Grant Program, supported by the John Deere Foundation, aims to enhance participation in STEM for underserved youth. Teams must apply for the grant before registration and ensure compliance with eligibility criteria, including training requirements. This initiative is part of John Deere's commitment to fostering diversity and inclusion in technology and engineering fields, ultimately seeking to impact one million youth by 2030.

The 1772 Foundation, in collaboration with the National Preservation Partners Network, is opening its 2026 grant cycle for Historic Property Redevelopment Programs (HPRP). This initiative aims to support nonprofit organizations in the U.S. focused on historic property revitalization. Eligible organizations must hold a 501(c)(3) designation and be NPPN members. Grants typically range from $50,000 to $75,000, promoting sustainable practices that address community revitalization and heritage conservation.

The PLTW Launch program, in partnership with the John Deere Foundation, aims to enhance STEM education access for underserved communities. This initiative supports schools in implementing PLTW Launch modules, fostering equitable opportunities for students. With a commitment to enroll at least 50% of students from the Free and Reduced Lunch program, the program focuses on real-world skills development to prepare youth for future challenges. The goal is to empower one million students by 2030.

The PLTW Gateway program, supported by the John Deere Foundation, aims to enhance STEM education access for underserved communities. By 2030, they intend to assist 1 million youth through inclusive educational opportunities. Schools within 40 miles of John Deere facilities can apply for grants to implement PLTW Gateway units, promoting real-world skill development. Priority is given to schools that demonstrate need and ensure student enrollment in these programs, fostering a strong foundation for future success.

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The Petfinder Foundation has been helping animal shelters and rescue groups since 2003. We are the ONLY national organization that does nothing but give cash and product grants to adoption groups.

Operation Grant

Grants vary depending on the organization’s need to support the number of adoptable pets listed on Petfinder and are awarded on a monthly basis throughout the year until all funds are depleted.

The Armstrong Foundation, established in 1949, focuses on funding educational initiatives that promote the significance of the U.S. Constitution. To be eligible, organizations must provide an IRS determination letter confirming their 501(c)(3) status. This foundation aims to enhance public understanding and appreciation of constitutional values through various educational mediums.

The JSF Scholarships aim to empower economically disadvantaged students by providing financial assistance for their education. This initiative addresses barriers to education and employment, enabling students to achieve academic success and meaningful careers. The Foundation supports various scholarship programs, partnering with schools and universities, and focusing on areas such as financial need and mentorship. By fostering educational opportunities, the JSF Scholarships contribute significantly to community development and individual empowerment.

The National Art Education Foundation (NAEF) is currently on a strategic pause regarding grant proposals until fall 2025. NAEF is committed to enhancing visual arts education through innovative initiatives that support instructional practices, research, and leadership. By promoting professional development and advocating for the inclusion of visual arts in curricula, NAEF aims to enrich the educational landscape for art educators and students alike.

The Home Depot Foundation's Path to Pro Scholarship aims to support U.S. veterans and train skilled tradespeople. With a commitment of $750 million by 2030, the Foundation has already trained over 44,000 participants. The program collaborates with industry leaders to address the skilled labor gap, offering resources and training in various trades such as carpentry and plumbing. By providing opportunities for high school seniors and graduates, this initiative fosters career development in the home improvement sector.

The Peter H. Brink Leadership Fund, supported by the National Trust for Historic Preservation, aims to enhance the capabilities of preservation organizations through mentoring and organizational development. Grants cover travel and mentor honoraria, fostering collaboration and peer-to-peer learning. Applications are accepted year-round on a rolling basis, prioritizing those who previously applied but did not receive funding. Eligible applicants include Forum members and nonprofit organizations, with a focus on innovative ideas for mentorship opportunities.

The Cynthia Woods Mitchell Fund for Historic Interiors, established by George P. Mitchell in 1997, supports the preservation of historic interiors through grants ranging from $2,500 to $15,000. Eligible applicants include public agencies and nonprofits, while individuals may apply if their project involves a National Historic Landmark. The competitive selection process typically concludes within three months, with grant recipients required to match funds dollar-for-dollar. This initiative promotes education and planning activities crucial for maintaining historic interior integrity.

The Arnold O. Beckman Postdoctoral Fellowship offers researchers the opportunity to advance their studies in Chemical Sciences or Chemical Instrumentation. This program supports innovative research within fundamental chemistry and the development of new instrumentation. Candidates must be U.S. citizens or permanent residents, or DACA recipients, with a PhD in the chemical sciences anticipated by May 1, 2026. Mentorship from a qualified institution is required, fostering independent research capabilities in a collaborative environment.

The Electronics, Photonics and Magnetic Devices (EPMD) Program, funded by the National Science Foundation, promotes cutting-edge research in electronics and photonics. It aims to develop innovative micro-, nano-, and quantum-based devices that enhance applications across various fields, including healthcare, energy, and communication. By focusing on emerging technologies that prioritize miniaturization and energy efficiency, EPMD seeks to foster advancements in material sciences, enhancing device functionalities and reliability.

The NDEP STEM Open NFO invites innovative proposals for research and implementation of effective STEM education and outreach programs. This continuously open announcement from the Department of Defense encourages submissions that align with key initiatives, including support for community colleges and strategic partnerships. As funding becomes available, amendments detailing specific topics and submission guidelines will be released. Applicants must submit white papers to express interest in full applications for potential funding consideration.

The FY 2025 EDA Public Works and Economic Adjustment Assistance Programs aim to enhance economic growth and resilience in distressed communities. EDA invites ongoing applications for funding, focusing on innovative approaches that leverage regional strengths. The updated NOFO emphasizes timely reviews and outlines submission procedures for core programs under the Public Works and Economic Development Act. Grantees are encouraged to develop unique initiatives that foster lasting economic prosperity.

The Abbey Mural Prize, established in 1932, supports the creation and restoration of public murals across the United States. This prestigious award, administered by the National Academy of Design since 1940, emphasizes projects that enhance community engagement and social activism through art. Grants typically range from $10,000 to $40,000, with a total annual funding cap of $125,000. Eligible applicants include artists, architects, and nonprofit organizations committed to impactful mural projects.

The Anne S. Chatham Fellowship in Medicinal Botany, funded by the Garden Club of America, aims to protect and expand knowledge of medicinal plants. It offers a $4,500 grant to support Ph.D. students and recent graduates in pursuing essential research that may otherwise be inaccessible. This initiative not only fosters botanical research but also contributes to the development of therapies that enhance patient quality of life and potentially save lives.

The Zeller Summer Scholarship in Medicinal Botany, initiated by the Garden Club of America, supports US undergraduate students pursuing summer studies in medicinal botany. Established in 2003 in honor of Caroline Brown's family, the scholarship encourages students to engage in various educational projects and internships. Eligibility includes enrollment in an accredited US college, with restrictions on international applicants. This initiative fosters knowledge in the field, promoting environmental awareness and academic excellence.

The Joan K. Hunt and Rachel M. Hunt Summer Scholarship in Field Botany aims to promote the study of field botany among students in the U.S. by providing a $3500 annual grant for summer study opportunities. Eligible students include undergraduates and graduate students up to the master's degree level, who are U.S. citizens or permanent residents. The scholarship encourages hands-on experience in various botanical projects, enhancing the understanding and appreciation of botany in horticulture.

The Garden Club of America Fellowship in Tropical Botany aims to enhance the preservation of tropical forests by increasing the number of botanists with practical field experience. Established in 1983, the fellowship provides two grants of $5,500 annually for doctoral candidates pursuing research in tropical plant systematics and forest ecology. Eligible applicants include U.S. citizens or permanent residents enrolled in U.S. institutions, who are expected to complete their Ph.D. in Botany within two years.

The Centers of Research Excellence in Science and Technology (CREST) program, funded by the National Science Foundation, aims to strengthen research capabilities at Minority-serving institutions (MSIs). It encourages the integration of STEM research and education, promoting diversity within the workforce. Successful proposals are expected to demonstrate innovative strategies for broadening participation and achieving national competitiveness in research. CREST Centers will also foster partnerships that advance significant research themes, ensuring sustained support and development for underrepresented groups in STEM.

The Dog Enrichment Grant, offered by the Petfinder Foundation, aims to enhance the quality of life for dogs awaiting adoption through enrichment activities and items. Grants are available for play yard renovations (up to $3,000) and interactive items (up to $1,000). Applications are accepted monthly until funds are depleted, and the window closes on November 1. Eligible expenses must be utilized within three months, and reimbursement requests will not be accepted.

The Pittsburgh Conference Memorial National College Grant (PCMNCG) supports small college science departments by providing grants for scientific equipment, teaching aids, and library materials. With a maximum funding of $10,000, this initiative promotes excellence in science education and encourages proposals that demonstrate effective integration of requested resources into curricula. Eligible institutions must have fewer than 5,000 students, ensuring that funds significantly impact undergraduate science education across diverse fields.

The Pioneering Aerospace Capabilities, Engineering and Research (PACER) program is a 20-year Broad Agency Announcement (BAA) by the US Air Force aimed at advancing innovative aerospace technologies. This initiative encourages white papers and proposals for research and development to enhance technology readiness levels. It is designed to provide the warfighter with a decisive advantage through transformative technology solutions. Multiple awards are anticipated, allowing for a range of project durations and funding values.

The Polaris Trails Grants Program, launched in January 2006, supports off-road and snow clubs across the U.S. and Canada. This pioneering initiative funds projects that promote safe riding, trail preservation, and environmental protection. Organizations can receive up to $10,000 for trail development, safety initiatives, and maintaining land access. Eligible applicants include 501(c)(3) and 501(c)(7) organizations, while funds are not available for politically or religiously affiliated programs.

The Tailored for Troops Grant Program, initiated by the Disabled Veterans National Foundation, provides essential business attire to veterans seeking employment. This initiative addresses the unique challenges veterans face in the job market, including unemployment and the need for proper attire. By partnering with organizations that offer employment services, the program ensures that veterans receive necessary support in their transition to civilian careers, ultimately aiding in reducing homelessness among veterans.

The Find Your Light Foundation is committed to providing every child with access to quality arts education. By focusing on direct support for exceptional programs, along with education, advocacy, and outreach, they aim to highlight the importance of arts in youth development. Grants are awarded to arts education initiatives in low-income areas across North America, typically ranging from $5,000 to $15,000, with awards issued in the Summer and Winter each year.