Best Large Grants for Nonprofit Organizations in Wisconsin

The National Scleroderma Foundation supports pediatric scleroderma research with up to $500,000 in funding for new and established investigators. Their mission focuses on advancing medical research and promoting awareness of scleroderma, with the vision of improving the lives of those affected. This initiative aims to encourage innovative research that could lead to better treatments and a potential cure for pediatric scleroderma, enhancing support for affected families.

The NIA Academic Leadership Career Award (K07) provides funding for established investigators to strengthen research capacity in aging and Alzheimer's Disease. The program supports the development of educational infrastructure, mentorship, and career development activities. Key deadlines for applications include February 12, June 12, and October 12 from 2025 to 2027. This award is specifically for research not involving independent clinical trials, allowing applicants to gain experience in trials led by others.

The Student Research Grant in Early Childhood Language Development, funded by the American Speech-Language-Hearing Foundation, supports master's and doctoral students conducting research on early language development. With up to three grants of $2,000 each available, this initiative honors Arlene M. and Noel D. Matkin. Eligible candidates must be enrolled full-time in accredited programs, focusing on research that benefits young children facing language delays or disorders.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Richard J. & Irma E. Larson Scholarship Endowment Fund

The Richard J. and Irma E. Larson Scholarship Endowment Fund was established to help Aurora area high school graduates attend colleges and universities to further their education in the fields of law, teaching, Christian ministry and agriculture.

Richard, better known as Dick, and Irma are both graduates of Wartburg College in Waverly, Iowa. Dick received his Juris Doctor Degree from the University of Illinois College of Law. Irma earned her Master’s Degree from Northern Illinois University.

Irma has served on several community boards, including Child Welfare, the Aurora YWCA, P.E.O. Chapter DD, and The Mid-West Early American Pressed Glass Club. After retirement, she volunteered as a Court Appointed Special Advocate (CASA) for nine years.

The monetary value of each scholarship award varies depending upon the amount available in each individual scholarship fund. The most common scholarship award amount is $1,000 for a single year. Scholarships are designated as non-renewable one-year awards or renewable multi-year awards depending upon the scholarship fund criteria, as established by the donor of the scholarship fund.

The Native American Library Services Basic Grant (NAB) aims to enhance library services for Native Communities. By supporting the acquisition of materials, programming, and staff training, the program empowers Tribal libraries to adapt to evolving information needs. This initiative fosters knowledge centers that contribute to community wellness and cultural preservation. Through targeted project activities, the NAB program ensures that libraries effectively meet their users' diverse needs, promoting accessibility and engagement across the nation.

The A.J. and Sigismunda Palumbo Charitable Trust supports organizations committed to enhancing the lives of children and young adults. They focus on educational institutions, health-related initiatives, and community services in the St. Marys, Pennsylvania area. Grants are awarded to 501(c)(3) organizations demonstrating accountability and measurable outcomes, with a preference for projects that benefit the community at large. The Trust encourages collaborative funding efforts and endeavors that inspire hope and vision.

The Transport Phenomena (TP) program, supported by the National Science Foundation, aims to advance fundamental research in the transport of mass, momentum, energy, and species across various scales. This initiative focuses on innovative methodologies that enhance our understanding of single- and multiphase systems, thermodynamic processes, and combustion dynamics. By integrating theoretical, experimental, and computational approaches, TP seeks to connect microscale phenomena with broader engineering applications, ultimately contributing to national priorities in energy, biotechnology, and environmental sustainability.

The Rural Communities Opioid Response Program (RCORP) - Community Systems Development aims to enhance behavioral health systems in rural areas by providing funding for the development and expansion of services. This initiative supports the establishment of formalized networks to boost operational and clinical capacity, ensuring effective implementation of evidence-based substance use disorder prevention, treatment, and recovery services tailored to community needs.

About Us

Marshfield Area Community Foundation, Inc. is a public, 501-C-3 charity. There are 30 community foundations in Wisconsin and more than 750 in the nation. The purpose of all community foundations is to accumulate charitable dollars that impact a specific geographic region in areas such as education, the arts, economic development, recreation, environmental protection, health care, and social services. They may be relatively small, as we are (assets of $14 million), or very large, as is the Greater Milwaukee Foundation (assets over $400 million).

Most people are familiar with private foundations, established by individuals, families, or corporations. Typically, in order to establish a private foundation, one has to have considerable wealth. You could say Community Foundations are much more democratic. We are, in a sense, an umbrella foundation containing many small foundations. We call those small foundations “funds.”

Marshfield Area Community Foundation Scholarships

The mission of the Marshfield Area Community Foundation is “Connecting people who care with causes that matter to enrich the quality of life in the Marshfield area”. Education is a valuable tool and a cause that matters to all of us. Through assisting students with financial support to receive an education, not only do students and the families of those students benefit, but also our community benefits, which further allows us to achieve our mission of enriching the quality of life in the Marshfield area.

Staab Construction Scholarship (2025)

Pablo's Business Directed Giving (BDG) is an initiative by Pablo Foundation to support local 501(c)(3) nonprofits in the Eau Claire area. With contributions capped at $2,000 per quarter, the program empowers a diverse Care Committee from Pablo Group to identify organizations that align with the Foundation's mission of promoting sustainability in housing, health, education, and the arts, while emphasizing equity and inclusion in community development.

The UCAR Next Generation Fellowship offers graduate students a unique opportunity to engage in Earth System Science research while addressing societal impacts. With a $40,000 fellowship over two years, participants can expect mentorship from UCAR leaders and professional development training. This program encourages interdisciplinary exploration, allowing fellows to collaborate closely with experts, attend conferences, and build lasting networks. It aims to empower diverse students as future change-makers in the field, fostering a commitment to equity and innovation.

The W. J. Blanchet Scholarship, offered by The Community Foundation for a Greater Richmond, supports graduating high school seniors from Northumberland County who demonstrate financial need and a commitment to academic excellence and community service. Preference is given to members of local churches. This scholarship aims to empower students to pursue higher education at accredited institutions, fostering educational growth and community engagement in the region.

Sony Corporation of America focuses its charitable giving on arts, culture, technology, and the environment, with a strong emphasis on education in these fields. It supports registered 501(c)(3) non-profit organizations while ensuring that their contributions encourage the development of the creative and technical skills essential for future workforce needs. Notably, multi-year requests and various exclusions, including those based on discrimination, are not considered.

The Clarence W. Seavers Citizenship Scholarship supports graduates from Erie County, Ohio high schools pursuing degrees in Political Science or Computer Science/Technology. With a minimum GPA requirement of 3.0, this scholarship can be renewed for up to three additional years at the discretion of the Scholarship Advisory Committee, without considering financial need. It emphasizes leadership, spirituality, and community service, aiming to empower students to contribute positively to their communities.

The Beaver Dam Area Community Foundation Impact Grant aims to enhance the quality of life in Dodge County by supporting impactful projects. Grants, ranging from $5,000 to $10,000, focus on endowment building, capital projects, capacity building, community leadership, community betterment, and startup initiatives. The Foundation exclusively funds organizations serving Dodge County, ensuring that each grant contributes to local growth and sustainability, while fostering innovative solutions to pressing community needs.

The FY 2027 Department of War Multidisciplinary Research Program (MURI) funds U.S. academic teams engaged in innovative basic research addressing future defense challenges. Established in 1985, MURI emphasizes collaboration across multiple scientific disciplines to tackle complex, DoW-relevant issues. By fostering partnerships among faculty, postdoctoral researchers, and students, the program aims to advance the U.S. defense industrial base and nurture a skilled scientific workforce, contributing to significant breakthroughs in military technology and economic growth.

The John Jamison Iron Mountain Education Fund provides scholarships to encourage educational pursuits among the children of Iron Mountain employees. Established in 2004, it awards $2,000 to selected applicants and $4,000 to those majoring in STEM fields. Eligibility includes dependent children of full-time employees at the Director level and below, along with deceased employees' children. The number of scholarships varies annually based on available funds, supporting students in their quest for higher education.

The National Institute of Environmental Health Sciences (NIEHS) is launching a funding opportunity for research hubs focused on the health impacts of extreme weather. This initiative encourages multidisciplinary teams to engage with community partners on issues such as wildfire smoke and extreme heat. Emphasizing collaboration, the program aims to develop scalable solutions and measurable public health outcomes, leveraging resources and expertise across institutions to address climate-related health challenges effectively.

About the Hertz Foundation

Empowering the Nation’s Most EXCEPTIONAL Innovators

The Hertz Foundation identifies and empowers the nation’s most exceptional innovators in science and technology, fueling a lifelong community dedicated to solving our most pressing problems.

Hertz Community

Awards & Recognition

We’ve established several awards to recognize and support Hertz community members who are accelerating solutions to significant real-world challenges, either through their individual careers or volunteering to strengthen the Hertz Foundation’s work. In addition to providing financial and professional support at a critical time, we also hope to generate more awareness within the Hertz community and inspire collaborations that build on the momentum.

Hertz Foundation Travel Fund

The Hertz Foundation Travel Fund provides financial support to Hertz Fellows to advance their professional growth through conference travel and interdisciplinary engagement. Awardees receive a lump sum of $2,000 for domestic or $5,000 for international travel.

Supporting professional development

Established in 2025, this funding provides Fellows with critical support to enhance their career and professional development. Funding is designated to support travel to attend technical conferences, interdisciplinary or entrepreneurial convenings and workshops or seminars that catalyze new career paths, research directions or cross-sector collaborations.

The Community Foundation for a Greater Richmond

The Community Foundation of Richmond is a philanthropic organization dedicated to improving quality of life across the Richmond region by connecting people, ideas, and resources for lasting community impact. The Foundation manages charitable funds, supports local nonprofits, and leads strategic initiatives that address community priorities such as education, health, economic opportunity, and equity. Through grantmaking, donor services, and community leadership, the Foundation works to strengthen nonprofits, respond to emerging needs, and build a more resilient, inclusive, and thriving Richmond-area community.

Virginia Urology Center Scholarship

The Virginia Urology Center Scholarship Program was established in 1999 to benefit graduating seniors from public and private high schools in communities where Virginia Urology offices are located, including Metropolitan Richmond, the Tri-Cities, Northern Neck, Middle Peninsula and South Hill. The scholarship supports post-secondary study in the fields of science and medicine. Funds awarded will help to cover the costs of tuition, room, board, books and laboratory fees.

Hendrix-Murphy Foundation

Enhancing literature & language at Hendrix College since 1978.

In homage to Bertie Wilson Murphy’s passion for the study and appreciation of literature and language, the Hendrix-Murphy Foundation at Hendrix College was founded in 1978 with an endowment by her son, Charles H. Murphy, Jr., former CEO of Murphy Oil Corporation. Mrs. Murphy was a 1905 graduate of Galloway Women’s College in Searcy, Ark., which merged with Hendrix College in Conway in the 1930s. Charles H. Murphy, Jr., was a member of the Hendrix Board of Trustees and served as chair. 

The Foundation's programs are overseen by a Board of Directors that is headed by the president of the College and includes Murphy family members, the provost, and representatives from the Hendrix Board of Trustees.

The Hendrix-Murphy Book Award

Hendrix is proud to offer the Hendrix-Murphy Book Award to an outstanding high school junior who demonstrates distinguished scholarship or leadership in literary studies (English, creative writing, foreign languages, or drama).

Hendrix-Murphy Book Award recipients will receive a copy of Poems to Read: A New Favorite Poems Anthology, edited by Robert Pinsky and Maggie Dietz.

Students may be nominated by their English, languages, creative writing, or drama teacher or guidance counselor by using the required form.

The Paul Calabresi Career Development Award for Clinical Oncology aims to enhance the training of clinician-scientists in clinical and translational cancer research. This funding opportunity encourages the career growth of researchers but does not permit Scholars to lead independent clinical trials. Instead, it allows participation in clinical trials under the mentorship of an experienced researcher, fostering a collaborative approach to cancer research.

The National Science Foundation (NSF) is offering Postdoctoral Research Fellowships in Biology to support innovative research at the intersection of Artificial Intelligence (AI) and Biological Sciences. These fellowships aim to cultivate expertise in both fields, enabling scientists to leverage AI for breakthroughs in biotechnology and bio-system design. The program encourages proposals that utilize existing biological data and infrastructure to enhance discovery and innovation, ultimately benefiting human lives and the U.S. economy.

The Grutzner Madeline Island Fund, managed by the Boreal Waters Community Foundation, supports initiatives that address the evolving needs of Madeline Island. Funding is available for projects focusing on health, education, children, cultural activities, and environmental efforts. Eligible organizations must be classified as charitable under IRS guidelines and serve the Madeline Island community. Priority is given to projects benefiting children and youth, while ongoing program support is considered a lower priority.

The FY 2023 Disaster Supplemental grant aims to support communities affected by major disasters, such as Hurricanes Ian and Fiona, by funding both construction and non-construction projects. This initiative focuses on long-term economic recovery strategies to address the challenges faced in areas with federal disaster declarations. Additionally, the Economic Development Administration has launched the Economic Development Grants Experience (EDGE) platform to enhance the efficiency and transparency of the grant management process.

The David G. & Jacqueline M. Braithwaite Scholarship, administered by the East Texas Communities Foundation, supports graduating seniors from East Texas planning to major in biology, mathematics, engineering, or related fields. This scholarship aims to empower students pursuing careers in medicine, veterinary medicine, or biotechnology. Financial need is not a consideration, and the scholarship is renewable, reflecting a commitment to education and community development in East Texas.

The David G. & Jacqueline M. Braithwaite Scholarship in Chemistry, offered by the East Texas Communities Foundation, supports graduating seniors from East Texas counties majoring in chemistry. This renewable scholarship emphasizes the importance of education in achieving dreams, with a preference for chemistry or biochemistry majors. Although financial need is not a consideration, students attending any college in the United States can apply, enabling broader opportunities for aspiring chemists.