Best Large Grants for Nonprofit Organizations in Wisconsin

The Clinical Data, Safety and Statistical Centers (CDSSC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance clinical research through comprehensive support. This includes statistical analysis, protocol development, and oversight of safety monitoring in studies related to asthma, autoimmune diseases, and transplantation. By coordinating these efforts, the program seeks to facilitate impactful research outcomes and improve public health outcomes through informed data-driven decisions.

The Howard D. Colman Scholarship supports high school seniors from Boone and Winnebago Counties pursuing degrees in engineering or technology fields. Established in memory of entrepreneur Howard D. Colman, the scholarship offers $2,500 in the first year, with potential renewal up to $10,000 for three additional years, contingent on meeting criteria. Recipients gain hands-on experience through internships with local firms, fostering connections to the Rockford area.

The NNLM Region 5 Professional Development Award offers funding for individuals at member institutions to enhance their knowledge and skills in health-related areas. This initiative aims to support meetings, workshops, and training that focus on health literacy, public health, and evidence-based practices. By fostering professional development, the NNLM seeks to improve healthcare services and access to health information across various communities, ultimately contributing to better public health outcomes.

Foundation of the Federal Bar Association

The Foundation of the Federal Bar Association provides the best way for practitioners to give back to the Federal legal community. Chartered by Congress in 1954, the Foundation serves people in communities across the United States through its generous grants, scholarships, and programming.

Our Mission: The Foundation’s mission is to:

• Promote and support legal research and education;
• Advance the science of jurisprudence;
• Facilitate the administration of justice;
• Foster improvements in the practice of Federal law

Foundation Grants

Foundation grants support community service projects and civics programs which comply with the Foundation’s mission to promote and support legal research and education; advance the science of jurisprudence; facilitate the administration of justice; and foster improvements in the practice of Federal law.

Civics Education Grant

The Civics Grant Program is designed to support projects and initiatives that promote a wider public understanding of democratic principles, the judicial system and the rule of law. Through targeted funding, the program empowers FBA chapters, sections, divisions, national standing committees (FBA entity), and other organizations to develop and support projects in their communities that foster public understanding of the rights and responsibilities of American citizenship, particularly among younger Americans.

Applicants may only receive one (1) Foundation grant per year.

The Eppley Foundation for Research, established in 1947, supports advanced scientific research in chemistry, physics, and biology. It prioritizes innovative studies, particularly in medical investigations and climate change. The foundation does not fund social sciences or projects with ample existing financial support. Applicants must hold a PhD or MD and be associated with a nonprofit in the US. The foundation aims to foster groundbreaking research that is unlikely to be replicated elsewhere.

Howard Hughes Medical Institute

More than 70 years ago, the Howard Hughes Medical Institute (HHMI) was founded with a mission to advance basic biomedical research and science education. Today, we invest in exceptional scientists at all career stages, catalyzing breakthroughs, new technologies, and the next generation of transformative clinical therapies. Our pathbreaking science takes place at more than 60 host institutions across the US, and at our Janelia Research Campus.

Cech Fellows Program

The Cech Fellows Program is a paid, nine-week summer research experience for rising college juniors and seniors designed to empower the next generation of scientific leaders through mentorship, hands-on research, and community. 

The Cech Fellows Program gives undergraduate students in the life sciences the opportunity to conduct hands-on research with leading scientists at HHMI laboratories across the US, from universities and research institutions to HHMI’s Janelia Research Campus outside of Washington, DC. Students are matched with HHMI scientists conducting fundamental research that advances our understanding of biology and health. 

This immersive program gives students the chance to contribute to real scientific discovery, receive professional mentorship, explore potential careers in biological and biomedical research, and connect with a community of like-minded peers.  

Gain Hands-On Experience in Research & Lab Work

The HHMI Cech Fellows Program is a 9-week, full-time, immersive research experience running from June 14, 2027 to August 12, 2027. Fellows: 

• conduct cutting-edge basic research in an HHMI lab for their own educational benefit  
• participate in professional development workshops   
• engage with a vibrant scientific community  
• build essential skills for future success in a scientific career   

Funding & Logistics 

As a Cech Fellow, students:  

• receive a $15,000 stipend if placed in an HHMI lab at a host institution, intended to cover travel, housing, meals, and incidentals. (Students are responsible for arranging their own housing.) 
• receive a $12,000 stipend if placed at HHMI’s Janelia Research Campus. (Students placed at Janelia have access to free, on-campus housing.)
• participate in an end-of-summer symposium at the Janelia Research Campus in Ashburn, VA, from August 10–12, 2027, at which they present their research and meet other Cech Fellows from across the country. Food, lodging, and travel to and from the symposium are provided by HHMI. 
• are matched with a local contact from their host lab who will provide suggestions for local housing options. Students are expected to travel to arrive at their host institutions by June 14, 2027.  

Cherokee Nation Foundation

The Cherokee Nation Foundation is a nonprofit organization serving the Cherokee Nation, a federally recognized tribe of more than 470,000 citizens. Its mission is to provide educational opportunities to Cherokee students so they can reach their full potential. The Cherokee Nation Foundation is a tax-exempt charitable organization under Section 501(c)(3) of the Internal Revenue Code.

Scholarships

Cherokee Nation Foundation offers a diverse range of scholarships to help reverse the trend of rising student debt. Students may receive up to two CNF scholarships per academic year. All opportunities are reserved for Cherokee Nation citizens, unless otherwise noted in the description.

Senior Master Sergeant Texie C. Taylor, USAF Memorial Scholarship

Applicant must be a junior or senior undergraduate or graduate student majoring in physics, chemistry, biology, medicine, nursing (RN), engineering (aerospace, civil, chemical, electrical, mechanical) or mathematics with a minimum 3.0 GPA. This is a one-year scholarship reserved for Cherokee Nation citizens residing within the Cherokee Nation jurisdictional area.

The Pablo Foundation Grant aims to foster a vibrant and sustainable community in Eau Claire by funding innovative projects over $10,000 that align with its vision and commitments to equity, diversity, and environmental sustainability. Established in 2017, the foundation has expanded its support beyond the arts to include housing, health, and education, focusing on initiatives that address specific community needs and benefit diverse populations.

The Spring - Health Care Service Grant Cycle, administered by the Archdiocese of Milwaukee Catholic Community Foundation, aims to support organizations providing essential health care services in the Milwaukee area, particularly in regions previously served by St. Anthony Hospital. This initiative is part of a broader commitment to philanthropy in Southeastern Wisconsin, focusing on health care for the underserved and fostering community well-being.

The Inspire Grants for Small Museums (2027) initiative, funded by the Institute of Museum and Library Services, aims to empower small museums across various disciplines. This program focuses on project-based funding to enhance public service through educational programs, exhibits, and community partnerships. By supporting small, often underfunded institutions, Inspire seeks to strengthen their capacity to engage communities and improve collections management, fostering experiential learning and discovery.

The Stout Foundation Grant supports organizations aligned with the values of its founder, Mr. Stout. Grants are awarded exclusively to entities with 501(c)(3) tax-exempt status and focus on charitable, educational, and scientific purposes. Preference is given to organizations with low overhead costs and those located in areas frequented by Foundation members. The Foundation aims to promote effective use of funds while remaining flexible in its grant-making approach.

About Father John Foundation GrantIn 1997 Monsignor John P. Hourihan established this perpetual charitable foundation for the purpose of funding care for the homeless and people with disabilities, especially the deaf and hard of hearing. The purpose of the Foundation is to financially assist churches and other non-profit organizations, that do not take more than insubstantial government funding, in administering their programs. Our giving focus is broad and considers programs that are: religious, educational, rehabilitational, social, and/or vocational. A priority is given to the deaf and homeless. All funding is given regardless of nationality, race or religion. The Foundation will continue its dedication to raising and distributing grants to be used by charities devoted to providing care and services to the homeless and disabled.

The Garden Club of America and the Royal Horticultural Society offer prestigious Interchange Fellowships aimed at fostering British-American collaboration in horticulture and landscape architecture. These fellowships provide American and British scholars with transformative experiences in the UK and US, respectively, focusing on hands-on horticultural work and education. The program includes financial support for travel and living expenses, ensuring fellows gain significant exposure to diverse horticultural practices and build valuable professional connections.

The Mid Wisconsin Grants, established under the Community Foundation of North Central Wisconsin, provide funding for nonprofit projects in communities once served by Mid Wisconsin Bank. The grants support initiatives in health, education, and community development. Eligible organizations must be tax-exempt entities based in specific Wisconsin locations. Potential applicants are encouraged to discuss their project ideas with grant officers before submission. Note that political or strictly religious purposes are not funded, and prior recipients are ineligible for two years.

The David C. J. Peters Scholarship, established by Southland Industries in honor of ASHRAE member David Peters, offers a one-year scholarship to qualified undergraduate students in mechanical or architectural engineering. Candidates must be enrolled full-time in a bachelor's program at designated institutions and maintain a minimum GPA of 3.0 or be in the top 30% of their class. This initiative supports the mission of ASHRAE to promote sustainable practices in engineering.

The Guido's Fresh Marketplace Scholarship Fund, established by the Berkshire Taconic Community Foundation, honors the legacy of Guido Masiero, a dedicated educator and entrepreneur. This scholarship aims to support graduating high school students from public schools in Pittsfield, Lenox, or Great Barrington, Massachusetts, who are pursuing higher education in physical education, health, wellness, or business studies. The fund reflects the foundation's mission to enhance community opportunities and economic mobility.

About Us

Our Mission

The Marfan Foundation drives research, education and support – and builds community – to improve outcomes, save lives and empower all people to thrive who are living with Marfan, Loeys-Dietz, Vascular Ehlers-Danlos syndromes, and related genetic aortic and vascular conditions.

Our Vision

Quality of life, longevity, and cures for all people with genetic aortic and vascular conditions.

Innovators Award

This is for faculty investigators for $100,000 over 2 years ($50,000 per year), to explore an innovative concept in “translational” science that has applicability to improving human health. Examples could include fundamental research, diagnostic tests, biomarkers, biomedical engineering advances, and imaging advances. Collection of data for improved evidence-based medical guidance are of great interest.

The SHAPE America: Joy of Effort Award recognizes dedicated individuals who exemplify the spirit of commitment and passion in health and physical education. Awardees are current SHAPE America members with at least three years of membership, demonstrating excellence in teaching, coaching, or leadership. This prestigious award celebrates those who have made significant contributions to the field, inspiring others to lead healthy, active lives through their efforts in education and advocacy.

The JoLyn Beeman Memorial Children’s Fund Grant supports projects enriching children's lives in Rock County, focusing on education, recreation, sports, and the arts. Established in 1997, this Fund has funded numerous initiatives, including playground equipment, educational resources, and special education projects. Grants are available to teachers and leaders, with a maximum funding limit of $5,100. The Fund aims to enhance community engagement and provide meaningful experiences for children.

The Amgen Foundation Inc focuses on non-healthcare donations and sponsorships that target humanitarian, social, educational, and community programs. They offer support to organizations outside the U.S. healthcare community, particularly those recognized as tax-exempt public charities. Eligible organizations must serve specific Amgen communities throughout the U.S. This initiative aims to enhance health outcomes and address critical societal needs, thereby reducing the burden of disease and improving lives.

Monarch Watch offers a Free Milkweeds Grant for habitat restoration projects aimed at supporting the monarch butterfly population. The program provides free milkweed plugs to schools and educational non-profits that demonstrate clear educational goals, long-term maintenance plans, and adequate space for the plants. With over 730,000 milkweeds distributed since 2015, this initiative plays a vital role in restoring habitats along key migration routes in the eastern and western U.S.

The Joe Booker Endowed Scholarship, administered by the Hamilton County Community Foundation, supports students in Indiana who advocate for limited government based on Judeo-Christian values. This scholarship aims to empower individuals to achieve their educational goals, promoting a community where everyone has equitable opportunities. Eligible applicants must maintain a minimum GPA of 3.0, and preference is given to residents from Arcadia or Cicero, IN. This initiative reflects a commitment to fostering civic responsibility and community engagement.

The National Institutes of Health (NIH) is dedicated to advancing emergency care through the Strategies to Innovate Emergency Care Clinical Trials Network (SIREN). This initiative seeks to establish clinical enrollment hubs that will enhance the network's ability to conduct trials aimed at improving outcomes for patients experiencing neurological and cardiovascular emergencies. Although applications are not currently being accepted, this notice encourages potential applicants to prepare collaborative and impactful proposals.

The A.J. Muste Memorial Institute's Social Justice Fund Grant supports grassroots activist projects in the U.S. and abroad, focusing on those with limited funding access. Prioritizing efforts to dismantle systemic injustices, the grant seeks proposals from organizations lacking mainstream support, especially those addressing issues like immigration violence, racial inequalities, and economic exploitation. The fund emphasizes direct activism and diverse leadership, making it a vital resource for community-driven initiatives in the pursuit of social justice.

The Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program aims to support federally recognized AI/AN Tribes and organizations in developing a workforce of researchers focused on AI/AN health disparities. This initiative, funded by the NIH, provides phased support for training and mentoring activities that equip individuals with the necessary skills to conduct culturally responsible biomedical research, ultimately guiding them towards successful careers in the biomedical research field.

The C Spire Wireless Foundation provides sponsorships primarily focused on STEM education, aiming to enhance digital literacy and workforce development in underserved communities. Organizations eligible for support must be 501(c)(3) tax-exempt entities dedicated to these educational initiatives. Preference is given to projects based in the foundation's service region. Proposals should be submitted at least 90 days prior to events for consideration, with a review process taking two to three weeks.

The C Spire Wireless Foundation Grant supports STEM education initiatives in Mississippi, Tennessee, and Alabama. Aimed at 501(c)(3) organizations, it focuses on projects that enhance digital literacy, technology skills, and workforce development. With a commitment to community transformation, the foundation prioritizes local projects that improve tech education and broadband access, creating a stronger future for the region. Applications must be submitted 150 days before the event, with a review period of up to four weeks.