Best Health Care Grants in Pennsylvania

The Buhl Foundation Grant Program supports initiatives in Southwestern Pennsylvania that enhance community vitality and foster economic development. The foundation prioritizes projects in education, health, and employment, particularly those benefiting Pittsburgh's Northside neighborhoods. By focusing on resident-led initiatives, the foundation aims to empower local communities and ensure sustainable growth. Applicants must be 501(c)(3) tax-exempt organizations, with funding preferences for projects that revitalize neighborhoods and improve access to vital resources.

The Alcon Foundation focuses on enhancing global eye health through charitable monetary donations to 501(c)(3) organizations. Grants aim to support programs that improve access to quality eye care and education, fostering community development. Eligible applicants must demonstrate high-quality services, well-defined goals, and the ability to report outcomes. The foundation does not fund organizations that discriminate or are not 501(c)(3) compliant, ensuring that resources are directed towards impactful initiatives.

Highmark Corporate Giving is dedicated to enhancing community health and economic resilience across its service areas. With a focus on equitable access to healthcare and support for local organizations, Highmark aims to reduce health disparities and promote well-being. Their initiatives, such as the Bright Blue Futures program, provide funding to impactful community projects, supporting a diverse range of organizations that align with their mission of fostering healthier, more vibrant communities.

The Highmark Foundation provides high-impact grants aimed at enhancing community health in Pennsylvania and West Virginia. It supports evidence-based programs that address critical health issues, including chronic diseases, family health, and access to care. The Foundation prioritizes initiatives that demonstrate sustainable solutions and collaboration with community partners. By funding diverse health-related projects, it aims to improve the well-being of underserved populations, ensuring that vital health interventions reach those in need.

The Hillman Foundation, established in 1951, aims to enhance the quality of life in Pittsburgh and southwestern Pennsylvania. It focuses on strategic grantmaking for economic development, health, education, human services, the arts, and the environment. The Foundation prioritizes initiatives that foster community growth, support arts and culture, and address social determinants of health. It primarily funds tax-exempt organizations serving the ten counties of southwestern Pennsylvania.

The PDCED Appalachian Regional Commission Grant supports economic development in Pennsylvania's Appalachian Region. It funds projects that enhance job creation, improve infrastructure, and promote business development. The goal is to leverage federal, state, and local resources to strengthen the economy of this 205,000-square-mile area. Funding is prioritized for initiatives that lead to sustainable economic growth, workforce readiness, and improved community capacity. Eligible projects include technical assistance, infrastructure development, and local government support.

The Tuttleman Foundation, established in Philadelphia in 2003, provides grants ranging from $1,000 to $250,000 to 501c3 organizations. Guided by the legacy of Stanley and Edna Tuttleman, the foundation focuses on areas such as education, community building, health care, arts and museums, basic human services, and spirituality. Their engaged philanthropy aims to support enduring benefits for the communities they serve, reflecting the founders' commitment to impactful giving.

The William G. McGowan Charitable Fund provides grants focusing on Education, Human Services, and Healthcare initiatives. The fund prioritizes programs with measurable outcomes that aim to alleviate poverty and suffering. Eligible organizations must be 501(c)(3) nonprofits and align with the fund's mission to create sustainable change. Applications are accepted by invitation only in specific regions, with a rolling deadline. The fund seeks collaborative efforts to maximize impact across its program areas.

The McLean Contributionship Grant, established in 1951, supports charitable projects in the Greater Philadelphia area, focusing on Arts, Education, Environment, and Health. The Trustees prioritize long-term benefits through capital projects rather than ongoing operational expenses. They favor initiatives that enhance community understanding of the environment, promote inclusivity, and improve care for the aging, all while fostering education and cultural developments. The foundation seeks to empower young talent and enhance service delivery in the region.

The Pittsburgh Foundation aims to foster a vibrant, equitable, and just community in the Pittsburgh region through its Foundation-Directed Grantmaking. Focus areas include Basic Needs, Equity and Social Justice, Arts and Culture, Economic Mobility, and Environmental Action. The Foundation prioritizes support for organizations serving low-income communities and those impacted by social injustices. By aligning grantmaking with community aspirations, they strive to ensure everyone can thrive and access essential resources and opportunities.

The Kenneth A. Scott Charitable Trust Grants focus on enhancing the quality of life for companion animals and native wildlife. This private foundation supports innovative projects that go beyond basic care, ensuring the well-being of homeless and abused animals. Eligible organizations must have a 501(c)(3) status and be located in specific states, including Ohio and parts of Indiana and Michigan. The Trust emphasizes humane treatment and sustainable funding for animal welfare initiatives.

The Snee-Reinhardt Charitable Foundation Grant supports transformative programs in Pittsburgh and surrounding areas, focusing on arts, education, environmental health, and human services. With an emphasis on tangible outcomes, the foundation values projects that serve large community segments. Eligibility requires organizations to have 501(c)(3) status for three years, while ineligible requests include fiscal sponsorships and general operating expenses. The foundation prioritizes local initiatives, particularly from Southwestern Pennsylvania and Northern West Virginia.

The Wawa Foundation offers financial grants exceeding $2,500 to 501(c)(3) non-profit organizations in its six-state market, focusing on health, hunger, and supporting everyday heroes. Applications are accepted in January, April, July, and October, with grant requests reviewed prior to the next submission window. Eligible organizations include those working to improve lives through health initiatives, hunger relief efforts, and support for community heroes. For more details, visit the Wawa Foundation's official site.

The Alcon Foundation Grant aims to enhance eye care services and improve patient access, with a focus on educational and training programs. The foundation also supports cultural and community development initiatives that uplift the quality of life in areas where Alcon operates, including cities like Fort Worth, Houston, and Irvine. However, it does not fund non-501(c)(3) organizations, athletic leagues, or fundraising events, among other exclusions.

The Neag Foundation Grant aims to foster positive change in education, healthcare, and the arts. Supporting initiatives in Pennsylvania and Connecticut, the foundation focuses on enhancing educational opportunities, advancing healthcare interventions, and promoting the arts and humanities. By encouraging innovative projects that receive community support, it seeks to improve the quality of life for individuals and families. Organizations with a 501(c)(3) status are encouraged to apply for funding opportunities that align with these goals.

The Bayer Fund Health & Wellness Grant Program aims to support organizations that provide education and resources for patients and caregivers facing cancer and cardiovascular diseases. Grants focus on assisting communities, particularly the African American population, in managing these health issues. Funding covers educational services, disease awareness, and access to care, with all activities to commence post-funding decisions. Eligible organizations must hold a 501(c)(3) status and operate within 55 miles of Bayer sites.

The Greater Harrisburg Foundation Upstream Grant aims to foster community improvement by funding innovative projects that address systemic issues at their source. This grant supports nonprofit organizations in Cumberland, Dauphin, Franklin, Lebanon, and Perry Counties, allowing them to implement creative solutions in areas such as education, health, and environmental stewardship. By focusing on upstream interventions, the foundation encourages a proactive approach to social change, ultimately enhancing community resilience and well-being.

The Joseph Kennard Skilling Trust Grant supports social welfare agencies in Philadelphia, enhancing community welfare through targeted programs. Established in 1963 by Joseph Kennard Skilling, the trust embodies his lifelong commitment to philanthropy. The foundation prioritizes effective programs, professional management, and community needs, while favoring organizations that assist vulnerable populations. Eligible nonprofit organizations under Section 501(c)(3) are encouraged to apply, particularly those addressing issues like elder care, youth at risk, and rehabilitation of the homeless.

The Just Born Corporate Giving Grant Program aims to enhance the well-being of children and families in need by supporting initiatives in arts, education, health, and community development. The program focuses on opportunities that benefit underserved populations, emphasizing diverse leadership and community engagement. Grants prioritize projects that promote cultural enrichment, educational access, and essential health services, ultimately fostering a collaborative and inclusive environment for all. Through strategic partnerships, Just Born Quality Confections is committed to making a meaningful impact in its local communities.

The Audrey Hillman Fisher Foundation Grant aims to enhance health and healing for communities through investments in the arts, education, human services, and environmental initiatives. With a focus on Pittsburgh, PA, Santa Barbara, CA, and Squam Lakes, NH, the foundation accepts grant applications year-round, with deadlines of January 5 for June funding and July 1 for November funding. The foundation prioritizes projects from new organizations within these regions.

The Cigna Group Foundation is launching the Improving Youth Mental Health Grant, committing $9 million over three years to enhance mental health support for youth aged five to 18. This initiative targets post-pandemic challenges, offering resources to parents, caregivers, and youth service professionals. Nonprofits are encouraged to apply for funding between $100,000 and $150,000 to develop programs that promote social-emotional skills, enhance caregiver support, and improve access to mental health interventions in underserved communities.

The Secular Distribution Grant supports charitable activities aimed at enhancing community well-being, particularly within 100 miles of Coatesville, PA. Focused on health and human services, the grant encourages projects that address community needs, foster self-reliance, and promote civic engagement. With a commitment to philanthropic impact, funding is reserved for organizations demonstrating 501(c)(3) tax-exempt status and a proven need, while maintaining strict eligibility criteria to ensure effective resource allocation.

The Provident Bank Foundation's Empowerment Grant focuses on uplifting marginalized communities by providing flexible funding for initiatives that promote economic self-sufficiency. With grants ranging from $5,000 to $25,000 over two years, the program supports organizations in education, human services, and workforce development. Eligible applicants must demonstrate meaningful community impact and align with the Foundation's funding priorities, which include promoting quality education, social safety nets, and career development opportunities.

The AmeriHealth Caritas Foundation Grant aims to prevent and mitigate adverse childhood experiences (ACEs) to promote healthier outcomes for children. With a focus on empowering families, healing behaviors, and access to healthcare, the foundation supports nonprofit organizations that provide comprehensive care and resources. Grants range from $100,000 to $250,000, totaling up to $1.945 million for project-specific initiatives. Eligible organizations must be 501(c)(3) nonprofits operating in states where AmeriHealth Caritas Medicaid markets exist.

Enterprise Community Partners

Enterprise Community Partners is a national nonprofit that exists to make a good home possible for the millions of families without one. Home is where life happens, where plans are made, and futures begin. It is the foundation for dignity, health, education, wealth, and community. Yet rents keep going up, paychecks don’t keep pace, and good homes in strong neighborhoods are increasingly out of reach.

The system doesn’t work. It must be changed, and it must be changed by us.

Enterprise has the breadth, scale, and expertise to do it. We support community development organizations on the ground. We aggregate and invest billions to improve housing and strengthen communities across the U.S. We advance housing policy at every level of government. We build and manage communities ourselves. Everything we do is informed by the residents we serve.

Together with our partners, we focus on the greatest need — the massive shortage of affordable rental homes — to achieve three goals:

• Increase the supply of affordable homes
• Advance racial equity after decades of systematic racism in housing
• Support residents and strengthen communities to be resilient to the unpredictable, and make upward mobility possible

Since 1982, we have invested $92.0 billion and created 1.1 million homes across all 50 states, the District of Columbia, Puerto Rico, and the U.S. Virgin Islands. We do all this to make home and community places of pride, power, and belonging.

National Housing Innovation Grant Competition

Home is foundational. It’s where we plant roots, raise and care for our families, and build community bonds. Yet in every corner of the country, millions of people of all ages and backgrounds need a home they can afford.

Wells Fargo is meeting this moment with a powerful grant opportunity. Together with Enterprise, Wells Fargo has launched the third iteration of the Housing Affordability Breakthrough Challenge. The 2026 cycle of the housing innovation competition will identify and propel proven, ready-to-scale solutions that transform current practices and increase housing choice and access.

Eligible applicants will compete for five individual grants of $2 million to advance their innovation and drive meaningful, systems-level change in the housing and adjacent industries. Winners will gain access to mentorship and coaching from industry leaders and experts and join a powerful network of Breakthrough Challenge innovators.

Focus Areas

This third cycle of the Housing Affordability Breakthrough Challenge aims to meet the nation’s affordable housing challenges across all types of communities: Native, rural, suburban, tribal, and urban.

Proposals must encompass one or more of three focus areas:

• Design and Construction
• Finance
• Service Delivery and Programs

Applicants will be asked to show how their proof of concept or pilot program has achieved clear outcomes and success, and provide a clear pathway to expanding the innovation’s reach and impact

Round 1: Criteria and Scoring

Your innovation must meet the criteria below to advance to the official scoring stage.

Type of Community

Innovations can serve all types of communities:

• Rural
• Urban
• Suburban
• Tribal

Location

Priority scoring will be given to applications from entities that are based in – or whose innovations are designed for – one or more of these 28 states, plus D.C.:

• Alaska, Arizona, Arkansas, California, Colorado, Florida, Georgia, Idaho, Illinois, Iowa, Maryland, Massachusetts, Minnesota, Montana, Nevada, New Jersey, New Mexico, New York, North Carolina, North Dakota, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, Utah, Virginia, Washington, Washington D.C.

Affordability

Innovations must serve residents at these income levels:

• Rental: 80% AMI or below
• Homeownership: 120% AMI or below
• Workforce housing: 120% AMI or below

The Gladys Brooks Foundation supports innovative projects in libraries, education, hospitals, and clinics. Grants focus on resource endowments, capital construction, and equipment aimed at improving public access to information and educational resources. Eligible applicants must be 501(c)(3) organizations located in specific states and demonstrate that projects will be funded primarily by the grant. Applications for direct salary support or research projects are not accepted.

The Universal Leaf Foundation Grants support 501(c)(3) nonprofit organizations primarily in areas where Universal Leaf Tobacco Company operates. Focus areas include education for at-risk individuals, higher education, civic/community arts, and environmental initiatives. The Foundation emphasizes good corporate citizenship and community engagement through financial support and employee volunteerism. Organizations must operate within designated geographic areas and cannot be involved in political advocacy or restrict services based on demographics. Grants aim to enhance community well-being and educational opportunities.