Skip to main content
Main content

Best Brule County Grants for Nonprofits in South Dakota

Looking for grants for 501(c)(3) nonprofit organizations working in Brule County? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$3.26B

Total funding

$5K

Median grant

9,000+ grants
$3.26B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

9,007 Results based on applied filters

America’s Healthy Food Financing Initiative: Partnerships Program

The Reinvestment Fund Inc
Private
United States
US $200,000 - US $3,000,000
The purpose of America’s Healthy Food Financing Initiative (HFFI) is to improve access to healthy food in underserved areas, to support food supply chain resiliency, to create and preserve quality jobs, and torevitalize low-income communities by providing financial and technical assistance, either directly orthrough other partners and intermediaries, to eligible fresh, healthy food retailers and enterprises toovercome the higher costs and initial barriers to entry in underserved areas. HFFI offers fundingopportunities and technical assistance to eligible applicants.
Food Access & Hunger

Make a SPLASH! Grant Contest - Need-Based Award

MNY Group, LLC.
Corporate
United States
US $50,000 - US $65,000 in in-kind support
The Make a SPLASH! Grant Contest, co-hosted by Inside Edge Safety Surfaces, offers two all-expenses-paid awards for Life Floor safety surfaces, aimed at enhancing community splash pads. The Need-Based Award targets municipalities and non-profits demonstrating financial need, with design options including planks, bubbles, and geometric shapes. Grant values range from $50,000 to $65,000, depending on project size, ensuring safety and accessibility for all users.
Outdoor Recreation

Make a SPLASH! Grant Contest - Inclusive Design Award

MNY Group, LLC.
Corporate
United States
US $50,000 - US $65,000 in in-kind support
The Make a SPLASH! Grant Contest invites municipal entities and non-profits in the U.S. to apply for the Inclusive Design Award. This award recognizes splash pads that prioritize inclusivity and accessibility. Winners will receive a customized Life Floor safety surface, valued at $50-65k, promoting community engagement and safety. With two opportunities to win, this initiative aims to enhance splash pad designs, ensuring they cater to all individuals. Join us in making splash pads safer and more accessible for everyone!
Outdoor Recreation Diversity, Equity & Inclusion

Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) (350160)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
This funding opportunity aims to enhance health interventions for Native American populations, addressing significant disease inequities and unique sociopolitical factors. It supports research in developing, adapting, and testing culturally informed health strategies, ensuring sustainability and community involvement. Key deadlines for applications are October 21, 2024, 2025, and 2026 for standard grants, and January 7, 2025, 2026, and 2027 for AIDS-related grants, emphasizing timely participation.
Health Disparities & Social Determinants of Health Native American Services Indigenous Health Systems

Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
This funding opportunity aims to support research interventions that enhance health outcomes in Native American populations. It focuses on addressing significant health disparities through culturally informed research, including the development and testing of health promotion strategies and treatment interventions. The initiative encourages sustainable solutions tailored to community needs, leveraging existing strengths and resources to improve health equity and reduce disease morbidity and mortality. Applications are due on multiple deadlines from 2024 to 2027.
Health Disparities & Social Determinants of Health Native American Services Indigenous Health Systems

O'Reilly Automotive Foundation Grant

O'Reilly Automotive Foundation Inc
Private
United States
Unspecified amount
The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.
Economic Services & Development Homelessness Services Food Access & Hunger +12 more

Grief Reach: Changemaker- Supported School-Based Community Expansion

National Alliance for Children's Grief (NACG)
Private
United States
US $110,000 - US $160,000
The Grief Reach grant program, supported by the New York Life Foundation and the National Alliance for Children's Grief, invites innovative community expansion proposals to better serve grieving children. Eligible organizations can apply for funding up to $160,000 to enhance their programs, focusing on unique community needs. By collaborating with the Judi's House/JAG Institute, participants will receive essential training and resources for impactful program evaluation, fostering a supportive environment for children and families facing grief.
Mental Health & Psychiatric Diseases Youth Services Family Services +1 more

TruStage Foundation Grants and Sponsorships

TruStage Foundation
Private
United States
Unspecified amount
The TruStage Foundation focuses on fostering economic mobility through education and housing initiatives. By supporting K-12 literacy, mentoring, and affordable housing projects, the foundation aims to uplift marginalized communities. With a commitment to addressing racial and socioeconomic disparities, TruStage seeks to empower individuals and families to build a brighter future. Their funding is directed towards impactful programs that align with their mission, while avoiding causes that do not meet their criteria for economic mobility.
Literacy Tutoring & Mentoring Equitable & Affordable Housing +3 more

Felix E. Martin Jr. Foundation: Community Leadership Fund Grant

Felix E Martin Jr Foundation Inc.
Private
United States
Unspecified amount
The Felix E. Martin Jr. Foundation Community Leadership Fund provides essential support for leadership development in Muhlenberg County, KY. It aims to empower individuals and groups seeking innovative solutions to local challenges. Eligible applicants include those pursuing personal leadership growth or researching effective community strategies. The fund underscores inclusivity, welcoming diverse applicants without discrimination. This initiative fosters a vibrant community by equipping leaders with the resources needed to effect positive change.
All fields of work Civic Affairs Art & Culture +1 more

TFish Fund Grant

TFish Fund
Private
Eastern Asia, United States
Up to US $10,000
The TFish Fund Grant aims to alleviate poverty in East Asia by empowering small but impactful NGOs to achieve sustainability and transparency. Founded in 2011, the Transparent Fish Fund partners with select organizations that focus on poverty alleviation. By providing financial aid, capacity building, and promoting accountability, the fund bridges the gap between Western donors and local NGOs, fostering a philanthropic spirit while addressing the complex social issues faced in the region.
Asian American Services

Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed) (348960)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $400,000
This funding opportunity aims to support Early Stage Investigators (ESIs) in conducting preclinical HIV/AIDS research using Nonhuman Primate (NHP) models. Eligible applicants must have at least two years of postdoctoral experience and be within ten years of their terminal degree. The initiative aligns with the NIH Strategic Plan for HIV and HIV-Related Research, targeting the reduction of HIV incidence, development of therapies, and advancement in research areas related to HIV.
HIV / AIDS

Research Experiences for Undergraduates (348985)

National Science Foundation (NSF)
Federal Government
United States
US $5,000 - US $500,000
The Research Experiences for Undergraduates (REU) program, funded by the National Science Foundation (NSF), promotes active research participation among undergraduate students across various research areas. It supports two mechanisms: REU Sites, which engage multiple students in ongoing research, and REU Supplements, which enhance existing NSF-funded projects. Participants must be U.S. citizens, nationals, or permanent residents, and each REU opportunity has its unique application process.
Geoinformatics & Geospatial Sciences Biology Physics +14 more

Rails-to-Trails Conservancy: Trail Grants

Rails To Trails Conservancy
Private
United States
US $10,000 - US $25,000

Rails-to-Trails Conservancy (RTC) Trail Grants

RTC’s Trail Grants are building strong foundations in communities for equitable trail network development and activation—investing in transformative projects and programs that create more access to trails for more people across the country.  

Our grants support organizations at all levels—from local and national nonprofits to public agencies—with a focus on community-based leadership, engagement and long-term impact.  

Since 2008, RTC has provided over $3.7 million in grant funding to more than 280 organizations seeking to create, connect and maintain the nation’s trails, building vibrant trail networks that connect neighborhoods and regions, and make it possible for America to walk, bike and be active outside.

Trail Creation & Maintenance Pedestrian & Bike-Friendly Infrastructure

Trail Accelerator Grants- Spring Cycle Planning and Design

International Mountain Bicycling Association
Private
United States
US $10,000 - US $30,000
The Trail Accelerator Grants aim to enhance mountain bike trail communities by providing essential planning and design services. With funding between $10,000 to $30,000, these grants support local organizations in creating sustainable trail systems. The initiative encourages projects that increase access and promote community engagement, particularly focusing on diversity and inclusion. Applicants must demonstrate the capacity to match funds, ensuring collaborative efforts to improve trail networks and experiences for all riders.
Trail Creation & Maintenance Biking Pedestrian & Bike-Friendly Infrastructure

Mathematical Sciences Postdoctoral Research Fellowships

National Science Foundation (NSF)
Federal Government
United States
Up to US $190,000
The Mathematical Sciences Postdoctoral Research Fellowships (MSPRF) aim to support emerging leaders in mathematics and statistics. These fellowships enhance participants' research environments, ensuring significant scientific development. Awardees can choose between a Research Fellowship or a Research Instructorship, with funding available for research across various mathematical and statistical disciplines. Proposals are submitted directly to the NSF, and fellows must affiliate with eligible institutions or organizations.
Mathematics

Mathematical Sciences Research Institutes (349343)

National Science Foundation (NSF)
Federal Government
United States
US $1,500,000 - US $6,500,000
The Mathematical Sciences Research Institutes, supported by the National Science Foundation, serve as critical national resources aimed at advancing research in mathematics and statistics. These institutes facilitate the discovery and dissemination of knowledge while enhancing connections with related fields. Their activities attract top mathematical minds to tackle pressing problems and engage a diverse array of U.S.-based researchers, ultimately bolstering the impact of mathematical sciences across various disciplines.
Mathematics

Founders Project Fulfillment Grant

Children's Theatre Foundation of America (CTFA)
Private
United States
US $30,000
The Founders Project Fulfillment Grant, offered by the Children's Theatre Foundation of America (CTFA), is dedicated to supporting 501(c)(3) IRS-certified theatres with a strong commitment to artistic excellence for young audiences. Eligible organizations must have a minimum operating budget of $1,000,000 and a proven track record of diversity in leadership, making this grant a vital resource for fostering inclusive theatre experiences for children and families.
Theater Youth Involvement in the Arts Arts / Culture Access & Participation

Ash Grove Charitable Foundation Grant

Ash Grove Charitable Foundation
Private
United States
Up to US $25,000
The Ash Grove Charitable Foundation Grant supports public charities with 501(c)(3) status, focusing on capital projects that enhance community life in states where Ash Grove operates. With a commitment to environmental sustainability, education, and human services, the Foundation prioritizes funding for renovation and construction projects. Grants typically reach up to $25,000, aiming to foster better living standards and support local initiatives that are vital for community growth and resilience.
Community Services

Bell's Brewery Small Grassroots Grants

Bell's Brewery, Inc.
Corporate
District of Columbia, United States
US $500 - US $5,000
Bell's Brewery Small Grassroots Grants support projects focusing on water stewardship across the Great Lakes watershed. With grant amounts ranging from $500 to $5,000, eligible organizations can apply for funding to improve ecosystem health, enhance public health through better water resource management, and promote resilience against climate-related water risks. This initiative highlights Bell's commitment to environmental stewardship and community support in all 50 states and DC.
Water Resource Management Environmental Stewardship Climate Change Resilience & Equity +3 more

Pioneering Aerospace Capabilities, Engineering and Research (PACER)

US DOD: Dept. of the Air Force, Materiel Command
Federal Government
United States
Unspecified amount
The Pioneering Aerospace Capabilities, Engineering and Research (PACER) program is a 20-year Broad Agency Announcement (BAA) by the US Air Force aimed at advancing innovative aerospace technologies. This initiative encourages white papers and proposals for research and development to enhance technology readiness levels. It is designed to provide the warfighter with a decisive advantage through transformative technology solutions. Multiple awards are anticipated, allowing for a range of project durations and funding values.
Aerospace Engineering

Rupert Dunklau Foundation Grant

Rupert Dunklau Foundation
Private
Colorado, Iowa +5 more
Unspecified amount
The Rupert Dunklau Foundation Grant supports organizations with 501(c)(3) status, focusing on Lutheran Higher Education, Health and Human Care, and Faith Strengthening. Since its establishment in 1968, the foundation has aimed to provide financial resources to ministries within the Lutheran tradition, particularly in Nebraska and surrounding states. Eligible projects must align with the foundation's mission to promote the welfare of mankind through educational and health initiatives.
Lutheranism Health Care Access & Delivery Human & Social Services +1 more

Wild Animal Initiative: Seed Grants

Wild Animal Initiative
Private
Afghanistan, Albania +189 more
Up to US $30,000
The Wild Animal Initiative offers Seed Grants to support innovative projects in wild animal welfare research. These grants aim to facilitate early-career researchers and established scientists in testing new techniques and approaches that incorporate welfare assessments into ecological studies. The program emphasizes cost-effective solutions, focusing on improving the welfare of wild animals. Successful proposals will explore diverse themes such as wild fish welfare and near-term welfare interventions to address urgent animal welfare challenges.
Wildlife Health Ichthyology (Fish)

Arctic Research Opportunities (349724)

National Science Foundation (NSF)
Federal Government
Canada, Greenland +1 more
Up to US $330,000
The National Science Foundation (NSF) seeks proposals for Arctic research to enhance understanding of the rapidly changing Arctic environment and its social systems. This initiative encourages innovative research that connects the Arctic region with lower latitudes, aiming to improve projections of future changes. Collaborations with federal and international partners are encouraged for co-reviewing proposals. Proposals that extend beyond the Arctic must clearly articulate their relevance to Arctic knowledge advancement.
Oceanography Hydrology Environment +7 more

Leonard-Litz Foundation: LGBTQ+ Community Grants

Leonard Litz Foundation
Private
United States
Unspecified amount
The Leonard Litz Foundation supports LGBTQ+ organizations through grants that promote health, wellness, crisis intervention, racial justice, advocacy, and social assistance. Priority is given to organizations in the northeast U.S. and those serving communities of color and transgender individuals. Applications that clearly link funding requests to specific needs will receive stronger consideration. The foundation aims to foster a supportive environment for the LGBTQ+ community to thrive.
LGBTQIA+ Services Sexuality & LGBTQIA+ Rights

Cornerstone: Learning for Living- Planning Grants

The Teagle Foundation Incorporated
Private
United States
Up to US $25,000
The Cornerstone: Learning for Living Planning Grants, sponsored by The Teagle Foundation and NEH, aim to revitalize humanities education in higher learning. With a focus on transformative texts and faculty engagement, the initiative encourages diverse institutions to innovate general education. Grants up to $25,000 support curriculum reform and professional development, fostering a sense of belonging and community among students while enhancing their analytical skills and cultural awareness.
Education - Higher Education Humanities & Social Science Teacher Development & Training

Cornerstone: Learning for Living- Implementation Grants

The Teagle Foundation Incorporated
Private
United States
Up to US $300,000
The Teagle Foundation and the NEH are offering the Cornerstone: Learning for Living implementation grants to enhance the role of humanities in higher education. Aimed at revitalizing student engagement, the initiative supports diverse institutions in creating transformative curricula and fostering community. Grants of up to $350,000 over 24 months will fund faculty development, course redesign, and outreach efforts, ensuring sustainable humanities programs that benefit a wide array of students, particularly in STEM fields.
Education - Higher Education Humanities & Social Science Teacher Development & Training

Gilead Foundation Funding

Gilead Sciences Foundation
Private
Canada, Mexico +2 more
Unspecified amount
The Gilead Foundation offers funding aimed at creating equitable health opportunities for all. Through its Giving Together Program and the Creating Possible Fund, it mobilizes resources to support community organizations that address health disparities and promote education equity. By fostering employee volunteerism and matching contributions, the Foundation actively engages in building healthier communities. This holistic approach seeks to dismantle barriers to health access, ensuring a sustainable impact on individuals and communities.
Health Disparities & Social Determinants of Health STEM / STEAM Education Sustainability +1 more

Brule County Grants for Nonprofits Highlights

Looking for Brule County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Brule County grants recommended for your specific programs.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Grant Funding Trends in South Dakota

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in Brule County Grants for Nonprofits year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the Brule County Grants for Nonprofits given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Brule County Grants for Nonprofits changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538