Best Large Grants for Nonprofit Organizations in California

The National Institutes of Health (NIH) is seeking to enhance the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) through the establishment of a Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC). This initiative aims to improve emergency care outcomes by supporting trials that focus on effective treatments for non-stroke neurological and cardiovascular emergencies. Although applications are not currently being solicited, this notice allows potential applicants to prepare collaborative proposals.

The Grassroots Organizing National Grant Program, funded by the Ben & Jerry's Foundation, supports small, community-led organizations in the U.S. working to confront social and environmental injustices. Grants of up to $30,000 per year are available for two years, prioritizing organizations with budgets under $350,000. The program emphasizes grassroots organizing and community empowerment, inspired by the legacy of John Lewis. Eligible applicants must focus on collective action and local leadership to drive social change.

The Sandusky-Firelands Alzheimer’s Scholarship provides financial support to residents of Erie County, Ohio, pursuing degrees in the Medical and Health Care fields, particularly those interested in working with geriatric patients. Established in 1995 by a dedicated non-profit organization, this scholarship aims to enhance community well-being and quality of life. Renewals for up to three additional years are possible, depending on financial need and the discretion of the Scholarship Advisory Committee.

The NIAID aims to enhance our understanding of the interplay between chronic and infectious diseases through innovative precision systems biology research. By utilizing advanced technologies such as multi-omics and artificial intelligence, the initiative focuses on uncovering critical pathways that connect infections to chronic health issues. This multidisciplinary approach leverages longitudinal patient data to inform and improve prevention and treatment strategies, ultimately seeking to provide insights into disease progression and host-pathogen interactions.

The Fred C. Gloeckner Foundation Research Fund Grant, established in 2024, supports innovative floriculture research and education. This partnership between the Gloeckner Foundation and AFE aims to enhance advancements in floriculture through substantial funding. Grants are available for university and college projects, emphasizing significant research importance and public accessibility. Projects can include funding for research assistants and must be accompanied by detailed outlines. Indirect costs and salaries are not covered.

About AGC of California

Since 1920, we have worked together with our members to provide advocacy, education, career development, and networking opportunities to experienced and next generation construction and contracting professionals. From the moment you become an AGC member, we go to bat for you with state and local governments, while helping you connect with industry leaders through services, innovative programs, and events.

The AGC Construction Education Foundation (AGC CEF) provides resources, support, and training through innovative programs in order to attract, develop, and retain a strong, motivated, and skilled workforce. We believe construction careers transform lives. We connect people and communities to meaningful work and rewarding futures. We inspire the industry to be a place where people belong, grow and build lasting legacies.

AGC CEF Skilled Trades Scholarship

This scholarship is designed to support students pursuing post-secondary construction industry training programs. Scholarship amounts range from $500 to $2,500.

The Rocky Mountain Power Foundation supports arts and culture organizations through grants typically ranging from $2,000 to $5,000, with a focus on enhancing community vitality. Eligible organizations include nonprofits dedicated to performing arts, visual arts, and historic preservation. The foundation operates on a quarterly grant cycle, ensuring careful review of applications. Grants are limited to tax-exempt organizations, and the foundation does not fund projects outside its service areas in Utah, Wyoming, Idaho, Oregon, and California.

The Actions of Public Witness Grant, offered by the Unitarian Universalist Funding Program, provides matching grants of up to $1,500 to Unitarian Universalist congregations engaging in timely actions of public witness. This initiative supports efforts in social and environmental justice, encouraging congregations to mobilize during critical moments. Grants are available on a rolling basis and are intended for urgent projects that extend beyond the regular grant timeframe. Notably, individual applications are not accepted.

The John M. O'Quinn Foundation Grant, established in 1986, has contributed over $192 million to various charitable activities, focusing primarily on Houston and its surrounding areas. The Foundation supports tax-exempt organizations and governmental units, emphasizing conservation, education, healthcare, and programs for underprivileged youth. Grants are not available for type III supporting organizations, individuals, or foreign charities, ensuring a targeted impact within the local community.

Seattle Foundation is an agent of change, igniting powerful, rewarding philanthropy to make Greater Seattle a stronger, more vibrant community for all.

At Seattle Foundation, we believe that community is more than a place. It’s the shared understanding that our joy and well-being are tied to one another. Every day we work with nonprofits, philanthropists, and partners like you to strengthen community by igniting powerful philanthropy and advancing long-term solutions. Because it takes all of us to create a joyful region where every person can thrive.

HOLA at Microsoft Scholarship

This scholarship supports high school seniors who self-identify as Hispanic/Latino decent and is a U.S. citizen, permanent legal resident or be an individual granted deferred action status under the Deferred Action for Childhood Arrivals Program. Eligible applicants must plan to study Engineering, Computer Science, Computer Information Systems, Business Administration, Finance or Marketing at an accredited two- or four-year college, university, or vocational school. This scholarship is a $5,000 award with up to five (5) scholarships granted.

The Intellia Therapeutics UNCF Scholarship Program, in partnership with the United Negro College Fund, aims to support students pursuing careers in life sciences. With a commitment to educational equity, this program offers scholarships to eligible students who demonstrate financial need and maintain a minimum GPA of 2.75. By investing in future leaders, Intellia Therapeutics and UNCF continue to empower individuals and strengthen communities, ensuring that no mind is wasted.

The Native Entities Grant Program, initiated by NTIA under the Digital Equity Act of 2021, aims to support Indian Tribes, Alaska Native entities, and Native Hawaiian organizations. This program streamlines funding through a unified application for two significant initiatives: the State Digital Equity Capacity Grant and the Digital Equity Competitive Grant. By focusing on reducing administrative burdens, it enhances access to digital resources and equity in underserved communities.

John J. Murphy Family Scholarship

Named in honor of John J. "Jack" Murphy, Olean native and former CEO and Chairman of Dresser Industries, this scholarship was established initially through a grant from the Communities Foundation of Texas and is continued with donations from generous donors. Selection criteria includes scholastic achievement, school and community participation, demonstrated leadership potential and financial need.

What We Do

At the North Carolina Community Foundation, we bring together generous people and connect them to causes and organizations they care about.

Our mission is to inspire North Carolinians to make lasting and meaningful contributions to their communities.

Our Philanthropic Network

We believe in the power of permanent philanthropy to strengthen our communities and people. By stewarding and growing donors’ gifts, our philanthropic network makes a powerful impact through robust grants and scholarships programs.

Humphrey-Ragsdale Scholarship Fund

Criteria

Residents of Craven County or graduates of a Craven County high school who are pursuing higher education at a two-year or four-year college or university, community or technical college, apprenticeship program, or pursuing graduate school or other professional degree such as dental, medical, law or seminary. Preference for those with a connection to First Baptist Church of New Bern, including but not limited to a church member, family of a church member, employee or former employee, family of employee or former employee, or youth group member.

The Watershed Education Scholarship, offered by the North Bay Watershed Association (NBWA), provides financial support for students of all ages who reside or work within the NBWA boundary. This scholarship aims to fund educational endeavors in environmental sciences, engineering, or water industry certifications. With awards up to $1,000 announced annually, the NBWA encourages projects that promote stewardship and benefit the entire North Bay watershed community.

The Trent R. Dames & William W. Moore Fellowship, established by Dames and Moore in 1990, supports graduate studies for practicing engineers or earth scientists who are ASCE members. This fellowship aims to advance engineering science and enhance societal welfare through innovative applications in geotechnical engineering and earth sciences, addressing social, economic, environmental, and political issues. Annually, two recipients are selected to further their academic pursuits in these critical fields.

About

Created by the community for the good of the community, the GLCCF is here to turn problems into opportunities through strategic grant making and initiatives created to address our region’s most pressing needs. We work with you to identify your charitable goals, and we ensure that they are carried out efficiently.

Work with us to make the kind of impact you want to see in your community. Let us take on the financial complexities and paperwork, while you focus on the important things like fostering good works throughout our community.

When you give to the Greater Lake City Community Foundation, you are making an investment that will benefit the community, now and in the future.

GLCCF Personal Services Scholarship

To award annually a scholarship to a qualified applicant who intends to further his/her education toward obtaining training to work in the Personal Services area.

About Us

We are one of more than 750 similar tax-exempt public charities throughout the United States that work to make their community a better place to live. We are a local organization staffed by residents of the community and led by a board of trustees who have an in-depth knowledge of the issues that shape our County.

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

About Our Scholarships

Our scholarships exist thanks to local families, friends, and organizations who have partnered with the Community Foundation to memorialize or honor someone, celebrate their alma mater, or promote a chosen career field. The creation of a scholarship fund can affect the donor as much as the recipient. 

The Community Foundation of Washington County, MD offers more than 100 scholarships for graduating high school students and non-traditional students in continuing education. 

The Thomas J. Bowers Aviation Scholarship Fund

A scholarship fund created in honor of Thomas J. Bowers to provide scholarships to deserving Washington County students who are active members of the Civil Air Patrol and express a desire to pursue a degree in an aviation-related field.

The Philip W. Sheridan-Tighe and Bond Scholarship Fund, administered by the Community Foundation of Western Massachusetts, supports graduating high school seniors from Hampden and Hampshire Counties pursuing civil engineering at a four-year college. Applicants can receive up to $3,000 in scholarships, which may influence college financial aid. Eligibility extends to students enrolling in accredited post-secondary schools in the U.S., including those from diverse backgrounds and experiences.

Grants for Research About Urban Communication Issues

Since our launch in 2005, the Urban Communication Foundation has provided awards and grants to dozens of distinguished scholars, researchers, and journalists to recognize and support provocative work that contributes in significant ways to the discourse around urban communication issues.

While most of our recipients hail from academia and journalism, we also encourage submissions from other practitioners whose work will lend new insights into the discipline, raise broader awareness of related socio-political, economic, and cultural concerns, or influence public policy.

The Michael Brill Research Award in Urban Communication

Sponsored by the Urban Communication Foundation and the Environmental Design Research Association

The Michael Brill Award for Urban Communication, Design, and Human Behavior supports innovative research that seeks to enhance the quality of community life by examining human communicative behavior in the context of the technologies and the physical environments in which those interactions occur. This research should address and connect theoretical perspectives from the fields of communication, design and the social sciences. Research supported by the Brill Grant may focus on how physical community places influence the mode, nature, and content of human communicative behavior OR use a communication lens for examining community places and human activity.

The Building Communities of Recovery program aims to enhance access to long-term recovery support for individuals facing substance use disorders and co-occurring mental health issues. By empowering organizations to mobilize community resources, this initiative fosters a collaborative environment that promotes sustained recovery. Funded by the Substance Abuse and Mental Health Services Administration, the program emphasizes the importance of community connections in the recovery process, ensuring that individuals receive the support they need to thrive.

Local Data for Equitable Communities CFP

This call for proposals (CFP) invites eligible nonprofit organizations in the U.S. to apply for a grant to collect, analyze, and use data to address inequities in the physical, economic, and social conditions of a place. Improving these conditions is key to achieving health equity where health is no longer a privilege, but a right. Structural racism is one of the leading barriers that results in inequities in conditions within and across communities. The Robert Wood Johnson Foundation (RWJF) expects to award up to 30 grants of $50,000 each, with a period of performance of nine months. The Urban Institute, as the national coordinating center for this program, is collaborating with RWJF on program design, grantee support, and communications.

Local data can be valuable tools to make progress on building places that offer everyone the chance to be as healthy as possible. Community organizations and residents can use data to understand challenges, set priorities, advocate for what is important to them, and hold others accountable for promised changes.

The goals of the Local Data for Equitable Communities grant program are to:

• Inform public policy and improve the physical, social, and economic conditions of places
• Build local capacity to use data for action
• Strengthen the use of equitable data practices
• Document successful practices for more communities to learn from and adapt

Funding

• Type of Award: Awards funded under this opportunity will be structured as grants.
• Number of Awards: Up to 30 awards will be funded.
• Amount of Award: Each award will be up to and including $50,000.
• Award Duration: Awards will be nine months.

The NCI Pathway to Independence Award (K99/R00) supports early-stage postdoctoral researchers transitioning to independent faculty positions. This funding opportunity encourages talented individuals with clinical or research doctoral degrees to lead independent clinical trials. Applicants should aim to foster research careers in cancer control, prevention, and data sciences. This initiative provides essential support during the transition from mentored positions to independent research roles, enhancing the pool of independent investigators in cancer research.

The ACLS Digital Justice Development Grants, funded by The Mellon Foundation, aim to enhance justice and equity in digital scholarly practice. These grants support projects that engage with historically marginalized communities, including people of color and those with disabilities. By providing resources and coaching for sustainable project development, the program promotes inclusion in the digital humanities, ensuring that diverse voices contribute to shaping digital knowledge and cultural heritage.

About Us

Marshfield Area Community Foundation, Inc. is a public, 501-C-3 charity. There are 30 community foundations in Wisconsin and more than 750 in the nation. The purpose of all community foundations is to accumulate charitable dollars that impact a specific geographic region in areas such as education, the arts, economic development, recreation, environmental protection, health care, and social services. They may be relatively small, as we are (assets of $14 million), or very large, as is the Greater Milwaukee Foundation (assets over $400 million).

Most people are familiar with private foundations, established by individuals, families, or corporations. Typically, in order to establish a private foundation, one has to have considerable wealth. You could say Community Foundations are much more democratic. We are, in a sense, an umbrella foundation containing many small foundations. We call those small foundations “funds.”

Marshfield Area Community Foundation Scholarships

The mission of the Marshfield Area Community Foundation is “Connecting people who care with causes that matter to enrich the quality of life in the Marshfield area”. Education is a valuable tool and a cause that matters to all of us. Through assisting students with financial support to receive an education, not only do students and the families of those students benefit, but also our community benefits, which further allows us to achieve our mission of enriching the quality of life in the Marshfield area.

Marc & Undine Cross Memorial Scholarship (2025)

The Barbara J. Thompson Scholarship offers multiple one-time awards of $1,000 or more for high school graduates and current seniors from accredited schools within the Santa Cruz City Schools District. Eligible candidates must have a minimum GPA of 3.0, be U.S. citizens residing in Santa Cruz County for at least three of the past four years, and participate in activities such as employment, family care, community involvement, volunteer work, or sports.

FCA Foundation Scholarship

Award:

• One time award of $5,000.