Best Large Grants for Nonprofit Organizations in California

The Dr. Louis G. Economou Memorial Scholarship, established by the Saginaw Community Foundation, honors the legacy of Dr. Economou, a dedicated educator and community leader. This scholarship supports high school seniors in Saginaw County with a minimum GPA of 2.8 who demonstrate commitment to academics and extracurricular activities, particularly in varsity sports. Awards range from $500 to $4,000, aiming to assist students pursuing higher education or Career and Technical Education. The foundation emphasizes leadership, teamwork, and community service.

The Emily Anne Dressler Memorial Scholarship, established in 1993 by the Saginaw Community Foundation, honors a remarkable young woman whose joyful spirit touched many lives. This scholarship aims to support high school seniors from Saginaw County pursuing their educational goals, particularly in Career and Technical Education (CTE) fields. With awards ranging from $500 to $4,000, it empowers students to achieve their dreams while tackling the growing demand for skilled trades in today's job market.

The NIA Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) aims to create a secure, scalable cloud platform for genetic data related to Alzheimer’s disease. This initiative will enhance data accessibility, promote interoperability, and support rigorous research practices. By facilitating collaboration and providing robust analytical tools, the platform will maximize the scientific impact of AD/ADRD research, aligning with NIH goals for transparent and reproducible science, while addressing recommendations for broad access to high-value datasets.

Excellence Grant

The Community Foundation’s Excellence Grants provide much-needed support to nonprofits that dispense programs and services throughout the local community. Learn more about this year’s grantees who make an ongoing impact in the areas of Human Services, Seniors, Youth Development & Education and Arts & Culture! Each was chosen after careful consideration by our selection committee for the stellar work done every day for the benefit of our community members. 

Agog Open Call: Climate Futures + Immersive Media

This open call supports immersive media projects that help people better understand and respond to climate challenges and imagine what a better world could be.

We are looking for projects that use immersive technologies—including smart glasses, augmented reality, spatial sound, and mixed reality—to create more engaging, experiential forms of climate storytelling and civic participation.

The open call will support projects across a range of stages and formats, from early ideas to more developed work. What matters most is a compelling story or experience, a clear sense of purpose, and a thoughtful approach to bringing the work to life.

Grants may be awarded in denominations ranging from $25,000 to $200,000. In addition to funding, selected projects may receive mentorship, advisor support, and opportunities for partnership and distribution.

About Pfizer Grants

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders

There remains a scientific gap in understanding of the role of anti-TFPImediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Project Types and Area of Interest

Potential applicants are encouraged to identify and address preclinical/basic science data generation for TFPI modulation/rebalancing in their local setting. This may include:

• Rare bleeding disorders which arise from deficiencies in different clotting factors or pathway components but converge on a common functional endpoint which is an impaired thrombin generation (e.g., Factor II, Factor V, Factor VII, Factor X and Factor XI deficiencies, as well as von Willebrand disease).
• Other diseases such as Glanzmann's thrombasthenia (GT) that have a distinct pathophysiological mechanism.
• Other rare bleeding disorders whose mechanisms are not well understood (e.g., Bleeding Disorder of Unknown Cause, BDUC).

About Pfizer Grants

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Biochemical and Molecular Characterization of Marstacimab and TFPI Pathways 

This competitive grant encompasses research aimed at elucidating molecular and cellular mechanisms underlying marstacimab-TFPI interactions, including but not limited to differential expression of tissue factor and TFPI in various tissues, binding kinetics, and other biochemical properties. Projects should seek to advance foundational understanding of these interactions through innovative approaches in biochemistry, molecular biology, and related disciplines.

Project Types and Area of Interest

Projects that will be considered for Pfizer support will focus on basic science and fundamental biological understanding of Tissue Factor Pathway Inhibitor (TFPI), anti-TFPI Monoclonal Antibodies, and marstacimab. The areas of interest may include (but are not limited to):

• Basic biology of TFPI including interactions among key regulatory proteins in the intrinsic and/or extrinsic clotting cascades (e.g. Protein S being a co-factor for both Protein C and TFPI).
• Impact of differential TFPI expression within tissues and the role of various TFPI pools/isoforms in the regulation of coagulation.
• Pharmacology resulting from concomitant therapies added to anti-TFPI

Accreditation Sustainability Learning Community RFA

The Association of State and Territorial Health Officials (ASTHO), through the Public Health Infrastructure Grant (PHIG), is currently accepting applications for participation in a learning lab that will foster health department capacity to build a sustainable public health accreditation culture within their agencies. This opportunity is open to applicants from direct PHIG awardees at the state-, big city-, and county-level.

Building Capacity for Communicating Impact Learning Community RFA

Learn how to communicate about Public Health Infrastructure Grant impact through a new community of practice! Through peer learning, technical assistance, and practical tools, participating teams will build strategic leadership and communications skills to more effectively translate public health achievements into compelling messages for key audiences. All directly funded PHIG recipients (big-city, county, state/territory-level governmental public health professionals) are eligible to apply.

Bridging the Gap Scholarship 

This scholarship was established to honor the memory of Trey Powell and Bridget Horn, who were both Veterans that lost their battle with PTSD to suicide. The Stronger Together Foundation strives to bring awareness to the large number of Veterans who face crises and ultimately commit suicide, as well as provide support to the families left behind. 

Scholarship Total Amount: $2,000.00

• (Two) $1,000.00 Scholarships will be awarded

The Bedford Community Health Foundation offers a variety of scholarships for individuals pursuing certification, degrees, and advanced degrees in health-related fields. Students can be full-time nursing students, employed nurses seeking additional education, full-time allied health students, employed health providers wanting to specialize and high school students enrolled in the Governor’s Health Academy at Susie G. Gibson Science & Technology Center.

Allied Health and Graduate Studies Scholarship 

Allied Health/Graduate Scholarship is designed to assist those who seek to enter into or advance in a health-related field. This scholarship is for full-time students pursuing an undergraduate degree and for those pursuing a graduate degree in a health-related field. Examples of professionals and degree programs include dietitians, speechlanguage pathologists, physical therapists, respiratory therapists, audiologists, medical assistants, pharmacy technicians, diagnostic medical sonographers, dental hygienists, certified nurse’s assistant, nurse practitioner and licensed practical nurse to name a few.

Face the Future Scholarship

At Bubble, we believe the next generation of builders, creators, and changemakers deserves support.

The Face the Future Scholarship provides financial awards to students who embody our core values of authenticity, creativity, innovation, and community impact as they pursue their academic goals.

In 2026, we're awarding 20 scholarships totaling $55,000 to students across the U.S., UK, and Canada.

One recipient will also earn a Spring 2027 internship at Bubble's New York City headquarters.

Camden Property Trust Scholarship

Benefiting dependents of Camden employees.

About the Scholarship Award:

• Multiple scholarships awarded for the 2026-27 academic year. Award amount varies by college/degree type:
  • 4-year college and trade schools: $5,500
  • 2-year college: $3,000
• Reapply guidelines:
  • Students in a four-year degree program may reapply up to 3 years after initial award (maximum 4 years of funding)
  • Students in a two-year degree or certificate program may reapply up to one year after initial award (maximum 2 years of funding)

What can this scholarship be used for?

• The scholarship will be mailed directly to the student's college to be used towards tuition, required academic fees, and/or book expenses.
• Scholarship funding cannot be distributed directly to the student. Funding cannot be used for room and board, rent, meal plans, parking passes, or other similar living expenses.
• Scholarships cannot be used for a summer semester or for graduate degrees.

Samuel “Bo” Terry Scholarship Fund

Fund provides higher education scholarship assistance to needy and deserving students graduating from Roanoke City Public Schools.

Amount

• $500+

Rangeley Educational Fund

Fund provides scholarships to further the education of young men and women pursuing study in technical, vocational, academic, or professional fields.

Amount

$1,000+

Romero Family Scholarship Fund

Fund was established to provide scholarship assistance to further the education of able and deserving young men and women in their post high school education in the fields of either technical, vocational, academic or professional education, with preference given to students from Henry and Franklin Counties and the City of Martinsville.

Amount

• $2,500+

The Charles H. Adrean D.S.C. Post 625 Memorial Scholarship, established by American Legion Post 625, honors exceptional athletes graduating from schools within New York's American Legion District 5. This scholarship supports students in their pursuit of post-secondary education, including academic, professional, and trade programs. It remains accessible to recipients entering military service, allowing them to claim it upon returning. The foundation aims to empower youth through educational opportunities that contribute to personal growth and community service.

About Us

Midlands Community Foundation (MCF) is here to serve and add value to donors’ philanthropic needs by providing them an opportunity to “invest in the power of community.” It is our goal to identify current and emerging issues, channel resources to address community needs, and help prepare for the future.

MCF Mission

The mission of Midlands Community Foundation is to be a catalyst for lasting impact in Sarpy and Cass counties and to give opportunities to organizations and individuals to pursue their charitable goals.

Scholarships Through MCF

Midlands Community Foundation is committed to the futures of communities in Sarpy and Cass Counties, and across the country. Supporting higher education of students is a direct investment in the futures of these communities.

The Walt Secord “Always Sunny and 75” Memorial Trade Scholarship Application

The Fund shall annually distribute two (2) scholarships in the amount of $1,000 each.

The KUH P30 Resource Core Center funding opportunity invites applications for centers aimed at enhancing research in Kidney, Urology, and Hematology diseases. These centers will provide essential resources, including data and tools, to the research community, fostering collaboration through a national network with the Center Coordinating Hub. This initiative by the National Institutes of Health aims to drive innovative research and shared expertise for improved health outcomes.

The KUH U24 Center Coordinating Hub aims to foster collaboration among funded Centers within the NIDDK/KUHN mission. This initiative encourages the development and sharing of vital research resources, including data, reagents, and expertise, with the broader scientific community. By creating a national network, the program enhances research capabilities and promotes innovative solutions in kidney, urology, and hematology diseases.

The NIDDK Multi-Purpose Resource-Related Research Centers Cooperative Agreement (U2C) invites applications to enhance research capabilities in areas such as obesity and diabetes. These centers provide specialized services, including technical support and data coordination, primarily to clients at other institutions lacking necessary expertise. This initiative aims to bolster high-impact research through collaboration and experiential training, addressing critical health challenges aligned with NIDDK's mission.

About

Community Foundation of Greenville bridges philanthropy and purpose in Greenville County, helping people make their charitable giving simpler and more powerful for 70 years. We strategically match diverse needs and opportunities in Greenville County with philanthropic resources.

Vision:

Community Foundation of Greenville will be the leading catalyst for developing assets and unlocking potential to meet the needs of an inclusive and equitable community.

Mission:

Community Foundation of Greenville improves the lives of Greenville County residents through strategic philanthropy, community investment, and collaborative leadership.

Obermier Scholarship Fund in Memory of John N. Obermier, Edith M. Obermier and Mary Belle Obermier

Purpose

Mary Belle Obermier established this scholarship with a gift from her estate in 2012. Her intent was to help academically deserving students who need financial assistance to be able to attend college and to give preference to qualified students who are committed to a career in the United States Navy. The preference for naval students is in recognition of the US Navy careers of her deceased husband, John, and his deceased first wife, Edith, who were both veterans of World War II.

Criteria:

• Applicants must demonstrate financial need (economically disadvantaged).
• Applicants must have a current academic GPA of 3.0 or higher.
• Applicants must be enrolled/accepted to an institution of higher learning prior to applying.
• Applicants must submit one letter of recommendation from a teacher, employer, or clergy.

Preference in the selection process will be given in the following order to qualified students who are:

students who are committed to a career in the United States Navy

residents of Greer, SC

residents of South Carolina and

residents of all other states

Susan G Komen Breast Cancer Foundation

The mission of Susan G. Komen® is to save lives by meeting the most critical needs in our communities and investing in breakthrough research to prevent and cure breast cancer.

Susan G. Komen Career Catalyst Research (CCR) Grants

Susan G. Komen Career Catalyst Research (CCR) Grants foster promising breast cancer researchers who are in the early stages of their faculty careers by providing support for up to three years of “protected time” for research career development under the guidance of a Mentor Committee. We seek to support those who will emerge as the next key leaders in the fight against breast cancer.

CCR Research Focus: Research projects must be hypothesis-driven, breast cancer-focused studies. They may be considered basic, translational, clinical and/or population science in nature and should align with Komen’s research priorities and mission to save lives from breast cancer. 

The Earthwatch Institute's Teach Earth Fellowship connects K-12 teachers with scientists through immersive research expeditions. Celebrating 50 years, this program empowers educators to inspire students with hands-on environmental science experiences. Teachers gain confidence, collaborate with peers, and develop impactful curricula. The fellowship includes workshops, networking opportunities, and resources to enhance environmental education in classrooms. Participants return with renewed purpose, ready to engage their communities in conservation efforts.

The DoW Bone Marrow Failure Idea Development Award supports innovative, high-impact research aimed at understanding and curing bone marrow failure diseases. This grant is available to both Established Investigators and Early-Career Investigators, with no preliminary data required for applications. Reviewers assess proposals based on specific criteria tailored to the investigator's career stage. The focus is on achieving interpretable results that contribute significantly to the field.

The DoW Bone Marrow Failure Investigator-Initiated Research Award supports innovative research aimed at advancing the understanding and treatment of bone marrow failure. This funding opportunity encourages applications for translational and clinical studies, requiring preliminary data to strengthen proposals. Unique features include the ability for a partnering Principal Investigator to contribute to the research, thereby fostering collaboration while maintaining a focus on significant advancements in patient care.

The FY26 Bone Marrow Failure Research Program's Resource Development Award aims to create a multiomic atlas from human bone marrow failure samples. This resource will be open-access, providing essential data for researchers and clinicians to enhance their understanding of bone marrow failure diseases. A comprehensive Data Resource Sharing Plan is required to ensure timely availability of the developed resource, fostering collaboration within the scientific community.