Best Large Grants for Nonprofit Organizations in California

The NewSchools: Teaching Reimagined Grant offers a unique funding opportunity of $150,000 to $250,000 for innovative ideas aimed at reimagining the role of educators and enhancing student outcomes. With a focus on leveraging generative AI, the grant supports early-stage organizations and initiatives that prioritize diverse teaching strategies and community involvement. The application deadline is January 8, 2026, with a priority deadline of December 1, 2025, for updates on eligibility.

Dave Dupont Memorial Scholarship

The family remembers Dave as a very kind hearted, loving husband, father, and friend. He and his wife Sandi were married 35 years, and had 2 children Kyle and Danielle DuPont.

Dave loved to give back to his community, and attend as many fundraisers as he could. Dave would be proud to be able to give back to the kids in his community.

Family Medicine Cares USA offers grants up to $25,000 to support the establishment of new free clinics. Eligible applicants must either have opened or plan to open within six months of the application deadline and hold the National Association of Free and Charitable Clinics Seal of Excellence. Priority is given to clinics with an AAFP member as medical director and those engaging Family Medicine residents or medical students as volunteers. Applications are accepted annually from March 15 to July 15.

American Welding Society (AWS) National Scholarships

The National Scholarships are the most prestigious, high-dollar scholarships offered by the AWS Foundation. More than 130 donor-funded scholarships, totaling over $700,000, are available for students pursuing a bachelor’s or associate degree in welding or a related discipline. Scholarships range from $2,500-$10,000+. Applicants are required to submit two references and official transcripts.

National Scholarships are a crucial component of a country's commitment to promoting education and providing opportunities for its citizens to excel academically. These scholarships are designed to recognize and support outstanding students, enabling them to pursue their educational goals and contribute to the development of their nation.

The Brooks and Joan Fortune Family Foundation Grant supports educational, artistic, and outreach initiatives. Applications are accepted year-round, with a focus on projects that yield specific outcomes rather than general operating expenses. While historically centered in Indiana and Florida, the foundation welcomes proposals from across the country. Eligible organizations must hold a 501(c)(3) designation. This grant is an excellent opportunity for nonprofits aiming to make a tangible impact in their communities.

The Cohen Gordon B Great Scholarship Fund honors Judy Gordon's legacy as a dedicated social worker and educator in Duluth. This fund supports students overcoming adversity, encouraging their pursuit of two-year or four-year degrees. Eligible applicants are graduates from any Duluth high school, with a preference for ESL or non-native English speakers. The scholarship awards $2,000 for one academic year, emphasizing the importance of resilience and belief in every student's potential.

The Combined Pilot Research Grants by the Plastic Surgery Foundation (PSF) and the American Association of Plastic Surgeons (AAPS) aim to support innovative pilot studies in hand surgery and plastic surgery. Grants of up to $10,000 are provided for projects that enhance scientific knowledge and clinical practices. Eligibility requires applicants to be MDs, DOs, or PhDs in U.S. or Canadian institutions, and membership in AAPS is encouraged to facilitate collaboration and mentorship.

Arnold Ventures

Overview

Arnold Ventures (AV) is a philanthropy dedicated to improving the lives of Americans through evidence-based policy solutions that maximize opportunity and minimize injustice. We focus on improving systems where outcomes are falling short, incentives are misaligned, and the time is right for change.

To advance this mission, we invest in rigorous research to better understand the root causes of problems and strengthen the evidence base on what works to solve them. Using this evidence, we advocate for policy reforms and help build durable, bipartisan coalitions for lasting change.

Request for Proposals

Causal Research on the Impacts of K-12 School Policies 

The next several years present an important opportunity to shape the future of state K-12 education policy. States are making consequential decisions about curriculum, assessment, and accountability systems; school choice and governance policies; and teacher and leader workforce policies. High-quality research in these areas will help policymakers distinguish between reforms that are merely appealing and those that meaningfully improve student outcomes over the long term.

Through this request for proposals (RFP), Arnold Ventures seeks to support research studies that estimate the causal effects of actionable, politically viable U.S. K-12 education policies that can be influenced at the state level and have the potential to improve outcomes at scale. Competitive proposals should employ rigorous causal research methods and, where feasible, examine not only short-term educational outcomes but also longer-term impacts on postsecondary and/or labor market outcomes using administrative data. Given the pace of state policymaking, we place a high value on research that can inform decisions quickly and will give preference to studies that can be completed within 18 months of project kickoff and/or produce actionable findings by the end of 2028.

The Youth Leadership Fund, established by Sally and Rick Botzler, aims to foster youth leadership skills in underserved communities by supporting K-12 initiatives focused on environment, sustainability, and community responsibility. Grants of up to $1,500 are available for organizations that demonstrate measurable outcomes impacting youth and the local environment. The fund prioritizes projects reflective of diverse community needs and encourages collaboration with other partners.

The Community Foundation of Carroll County supports nearly 70 academic, sports, special circumstances, and 4-H scholarships. Search scholarships by name, or sort by application type.

Meghan Lynn Rippeon Memorial Scholarship

The purpose of the Meghan Lynn Rippeon Memorial Scholarship is to honor the life of Meghan Lynn Rippeon by providing a scholarship for any senior graduating from a Carroll County, Maryland high school who has shown academic achievement and is pursuing an education in early childhood development and who has been accepted at an accredited College, University, or Technical School. Applications will also be accepted from continuing students, i.e. those that are already in college, who meet the criteria established for this scholarship.

The Family Medicine Cares USA Free Health Clinic Grants support existing clinics in providing care to the uninsured. Grants of up to $10,000 are available if funds permit, prioritizing clinics with AAFP members in leadership roles. The program emphasizes the involvement of Family Medicine residents or medical students as volunteers, aiming to enhance healthcare access in underserved communities.

The Rapier Education Fund, managed by the San Antonio Area Foundation, supports high school seniors and college students pursuing degrees in the USA. Eligible applicants must maintain a minimum GPA of 2.5 and be enrolled full-time. The fund covers tuition, fees, and books, and is renewable for up to three years. Since 1964, the foundation has awarded millions in grants to enhance community living through education and other initiatives, making a lasting impact on the San Antonio area.

The Dr. Doris R. Corbett-Johnson Leaders for Our Future Award, presented by SHAPE America, honors young professionals under 36 who exhibit exceptional promise in scholarship, teaching, and leadership. This prestigious award is available in two categories: college/university and non-college/university, with a maximum of two recipients per category each year. By recognizing emerging leaders, SHAPE America aims to inspire a new generation dedicated to advancing health and physical education.

The Community Focus Grant Program, supported by the Robert H. Janssen Foundation, aims to enhance youth enrichment and sports programs within San Luis Obispo County. This initiative, reflective of the Search Institute's 40 Developmental Assets, promotes community inclusivity and mentorship. Grants target nonprofit organizations, focusing on direct service costs to ensure access for all youth, regardless of income, while emphasizing active participation in enriching activities.

The Radiation Oncology-Biology Integration Network (ROBIN) Centers, funded by the National Cancer Institute (NCI), aims to enhance national radiation oncology infrastructure through collaborative research. This initiative supports studies on biological responses to radiation treatment in cancer patients, focusing on understanding tumor and tissue changes. By integrating various scientific disciplines and collecting comprehensive data, ROBIN intends to improve cancer care, optimize treatment strategies, and accelerate translational discoveries to enhance patient outcomes.

The Shannon Revel Scholarship, offered by the Community Foundation of Monroe County, supports high school seniors in Monroe County pursuing a degree in environmental engineering. This initiative aims to empower the next generation of engineers dedicated to addressing environmental challenges, fostering a sustainable future. With a commitment to inclusivity and community development, this scholarship reflects the foundation's mission of making a difference through philanthropy and education.

Who We Are

Thousands of your friends and neighbors make up Samaritan Health Services. We’re a nonprofit network of hospitals, clinics and health services caring for more than 290,000 residents in the mid-Willamette Valley and central Oregon Coast and portions of Marion and Polk counties. We work together to provide highly reliable and innovative medicine with world-class quality in a way that supports the values of the communities we serve. That includes caring for all people, regardless of your ability to pay.

Linn County- Samaritan Lebanon Community Hospital Auxiliary Scholarship

East Linn County students currently attending college and majoring in a medical field are invited to apply for the Samaritan Lebanon Community Hospital $1,000 Auxiliary Scholarship.

The BioLEAP Classroom Grants, funded by the National Anti Vivisection Society, support U.S. educators in purchasing humane alternatives to animal dissection. Grants of up to $1,000 are available for innovative learning tools like 3D models and synthetic specimens. This initiative promotes ethical education in anatomy labs, ensuring teachers have access to effective resources while fostering a compassionate approach to learning.

Scholarship Opportunities

The Sioux Falls Area Community Foundation manages one of the state's largest scholarship programs, awarding more than $500,000 in scholarships to local students each year. If you’re interested in pursuing higher education, it's likely we have a scholarship that can help you achieve your dream.

Trent Area Scholarship

Organizers have defined the Trent community as the area bounded on the south by the Moody County line, on the north by SD Highway 34, on the east by the South Dakota state line, and on the west by the Colman Road, also known as 470th Avenue.

* Multiple scholarships are awarded

Biochemical and Molecular Characterization of Marstacimab and TFPI Pathways

This competitive grant encompasses research aimed at elucidating molecular and cellular mechanisms underlying marstacimab-TFPI interactions, including but not limited to differential expression of tissue factor and TFPI in various tissues, binding kinetics, and other biochemical properties. Projects should seek to advance foundational understanding of these interactions through innovative approaches in biochemistry, molecular biology, and related disciplines.

Funding Range and Project Length

Individual projects requesting up to $50,000 USD will be considered.

Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.

Maximum project length is 1 year.

The Combined Pilot Research Grants program, supported by the Plastic Surgery Foundation and various surgical organizations, aims to promote innovative research in hand and plastic surgery. With funding of up to $10,000 for one-year pilot projects, this initiative encourages the development of surgeon scientists and seeks to enhance research funding in the field. Eligible applicants must be medical professionals holding relevant positions in U.S. or Canadian institutions.

The Northern Wisconsin Outdoor Experiential Education Scholarship Fund supports residents of Chequamegon Bay communities in accessing quality outdoor education programs. Created by anonymous donors passionate about outdoor experiences, the fund targets applicants demonstrating financial need and belonging to underrepresented groups in outdoor education. Awards of $1,000 are available for one year, enabling youth to engage in environmentally sustainable outdoor activities and develop social responsibility.

The City of Berkeley's Community Festivals Grant supports diverse cultural events that engage the community and enhance Berkeley's reputation as a vibrant destination. Grants up to $7,000 are available for one-time festivals that are free and accessible to the public. Eligible applicants include nonprofit organizations and artist collectives. The grant encourages projects that celebrate cultural heritage and foster community involvement, while ineligible costs include administrative expenses and ongoing programming.

The Community Foundation of Carroll County supports nearly 70 academic, sports, special circumstances, and 4-H scholarships. Search scholarships by name, or sort by application type.

Legacy Septic and Excavation Scholarships

The purpose of the Legacy Septic and Excavation Scholarships is to provide scholarships for current students of Winter’s Mill High School, Manchester Valley High School, Westminster High School and Carroll County Career and Technology Center who have an interest in the environment and who meet the eligibility requirements set up for this scholarship.

The Skin Cancer Pilot Research Grants, funded by the Skin Cancer Foundation, support innovative studies in skin cancer prevention, detection, and treatment. With over $2 million awarded since 1981, these grants are aimed at early career dermatology investigators. Each year, researchers can apply for one-year projects, with a total of $125,000 available through two $50,000 grants and one $25,000 grant. This initiative is vital for advancing research and improving patient outcomes.

The Award for Graduate Study in American History, offered by the National Society of The Colonial Dames of America in the State of Illinois (NSCDA-IL), provides $3,000 annually to a graduate student. This award supports research that enhances understanding of America's development from colonial times to the present, with a preference for those intending to teach. NSCDA-IL fosters appreciation for our national heritage through educational initiatives and historic preservation.

The Patricia L. Hartman and Lois C. Hartman Scholarship Fund, managed by the San Antonio Area Foundation, supports current high school seniors and college students pursuing Associate or Bachelor's degrees in the USA. It aims to enhance educational opportunities, with a preference for applicants from Alamo Heights ISD. This fund reflects a commitment to improving community life through education, making a lasting impact on students' futures.