Best Large Grants for Nonprofit Organizations in California

The Frankenthaler Climate Initiative provides funding for energy efficiency projects in visual arts museums, addressing climate change through innovative cultural leadership. Grants up to $25,000 support institutions in evaluating energy mitigation opportunities, enhancing efficiency, and reducing emissions. Eligible applicants include museums and visual arts schools across the U.S. The initiative encourages sustainable practices while assisting organizations in understanding their energy needs and planning for effective interventions within a project timeline of 18 months.

The Clarence W. Winter Charitable Trust, established from Mr. Winter's Will, provides annual grants of $3,000 to $5,000 to support tax-exempt organizations focused on charitable, religious, scientific, literary, or educational purposes. While there are no geographic restrictions, the Trust prioritizes organizations in Bucks County, PA. With a commitment to community betterment, Mr. Winter's legacy continues to support impactful initiatives for years to come.

The Louder Than Words Grant Program, supported by the Finish Line Youth Foundation, focuses on empowering diverse and underserved communities in Indianapolis and beyond. With grant cycles addressing areas like health, workforce development, and safe communities, organizations can request up to $10,000 to support impactful programming. Eligible applicants must be 501(c)(3) organizations dedicated to fostering positive change, particularly for communities of color, ensuring equitable access to resources and opportunities.

The Holthouse Foundation for Kids supports organizations that empower at-risk youth through character education, life skills, and entrepreneurship. They provide grants to non-profit entities recognized under Section 501(c)(3) of the Internal Revenue Code, focusing on community enrichment in Houston and beyond. While inquiry letters are accepted year-round, they do not guarantee funding, and applicants must understand that proposals are not a promise of financial support.

The Joseph R. & Mercedes McMicking Foundation Grant aims to enhance the quality of life for children and families in the San Francisco Bay Area. It focuses on charitable giving, supporting educational programs in arts, technology, education, and science. The foundation provides grants to 501(c)(3) organizations, promoting access to resources and tuition assistance for local pre-K-12 schools. This initiative strengthens community ties and nurtures the next generation's growth through diverse educational opportunities.

Driving University Impact: Expanding the Public Exchange Network Grant

How the Public Exchange Network Works

No single university – even a large R1 – has enough faculty expertise available to meet the needs of every partner. The Public Exchange Network was designed to help universities work together seamlessly to build robust partnerships and generate more collective impact. Universities joining the network are independent but affiliated members, with full control over their own program and project portfolios. As a national network with local, on-the-ground capacity, Public Exchange Network members can also share approaches that work, scale solutions to common problems, and build cross-regional partnerships together. 

As an institutional partner in the Public Exchange Network, universities will build capacity to develop, test and implement solutions to the most urgent problems in their regions and beyond. Universities joining the Public Exchange Network get:

• The tools, templates and training they need to start right away;
• A shared brand they can plug into on day one;
• A network of faculty, past and potential partners and philanthropic relationships, benefitting everyone in the network. 

Public Exchange Network Expansion grants will cover 75-80% of the minimum estimated annual costs for two years to launch a new Public Exchange. To launch a Public Exchange, universities must have the following in place: (1) a staff executive director with experience launching and leading social impact partnerships, (2) a project seed fund, and (3) a modest operations budget. We also recommend some in-kind project management support from an existing university staff member. The grant includes a two-year Public Exchange Executive Director (ED) compensation subsidy of $300,000 to launch the Public Exchange on campus, and a 2-year license to use the Public Exchange brand. New Public Exchange Network members will also receive ongoing support and guidance from current Public Exchange leadership and staff at USC and WashU, including recruitment support and intensive training for hiring and onboarding an executive director, a sub-site on the Public Exchange website, incubation and project management support from current Public Exchange staff, and a suite of tools for developing and implementing Public Exchange projects.

The Niles Rotary Club Grant, established in 1937, supports local charitable projects in Fremont. With a focus on community significance, eligible non-profit organizations can apply for funding ranging from $500 to $5,000. The grant emphasizes measurable objectives and life-enhancing initiatives. The club also seeks matching funds from Rotary District and International to enhance its outreach, ensuring a lasting impact on the community.

The Tribal Institutional Review Board Establishment and Enhancement (TIRBEE) award aims to assist federally recognized AI/AN Tribes, Tribal colleges and universities, and Tribal health organizations in creating or enhancing Institutional Review Boards (IRBs). This initiative is crucial for ensuring ethical research practices within Tribal communities, fostering cultural sensitivity in research, and protecting the rights of AI/AN participants. Applications must be submitted by 5:00 PM local time of the applicant organization.

The National Institutes of Health (NIH) is set to publish a Notice of Funding Opportunity (NOFO) for research on isolated human islets as a diabetes treatment. This initiative aims to gather data from clinical trials, aiding the research community in future publications and trial designs. While applications are not currently being accepted, potential applicants are encouraged to start forming collaborations and consider applying when the opportunity opens.

The Armando "Frank" Quaglia Veteran's Scholarship, offered by the Grand Rapids Community Foundation, supports full-time graduate or upper-level undergraduate students from Kent or Ionia County pursuing healthcare or engineering degrees. With a minimum 3.0 GPA, preference is given to veterans and their families. This scholarship aims to eliminate barriers to education, fostering academic success and connecting students to opportunities in West Michigan's inclusive community.

The AAAE Diversity, Equity & Inclusion Scholarship, provided by the AAAE Foundation, supports ethnic diversity students pursuing aviation studies in the U.S. or Canada. With two awards of $5,000 each, recipients are chosen based on their academic achievements, financial need, and community involvement. Eligible applicants include college juniors, seniors, or graduate students with a minimum GPA of 3.0. This scholarship aims to foster future leaders in the aviation industry, enhancing diversity and inclusion.

About Us

Marshfield Area Community Foundation, Inc. is a public, 501-C-3 charity. There are 30 community foundations in Wisconsin and more than 750 in the nation. The purpose of all community foundations is to accumulate charitable dollars that impact a specific geographic region in areas such as education, the arts, economic development, recreation, environmental protection, health care, and social services. They may be relatively small, as we are (assets of $14 million), or very large, as is the Greater Milwaukee Foundation (assets over $400 million).

Most people are familiar with private foundations, established by individuals, families, or corporations. Typically, in order to establish a private foundation, one has to have considerable wealth. You could say Community Foundations are much more democratic. We are, in a sense, an umbrella foundation containing many small foundations. We call those small foundations “funds.”

Marshfield Area Community Foundation Scholarships

The mission of the Marshfield Area Community Foundation is “Connecting people who care with causes that matter to enrich the quality of life in the Marshfield area”. Education is a valuable tool and a cause that matters to all of us. Through assisting students with financial support to receive an education, not only do students and the families of those students benefit, but also our community benefits, which further allows us to achieve our mission of enriching the quality of life in the Marshfield area.

Sophia Smrz Memorial Scholarship (2025)

The LAFLA LEIF Fellowship Program empowers underrepresented law students to pursue public interest careers. Launched in 2021, it provides fellowships to select summer law clerks, addressing inequities in the legal profession. Along with participation in the Summer Law Clerk Program, LEIF fellows engage in weekly meetings and complete a final project. They are eligible for up to $10,000 in educational reimbursement for tuition, fostering a community dedicated to equal justice.

The Permanente Medical Group (TPMG) Informatics Fellowship offers a 1- to 2-year program focused on clinical informatics, leveraging data science and health technology to enhance care delivery. Nestled within the Kaiser Permanente Northern California Division of Research, this fellowship encourages innovative approaches to address healthcare challenges. Mentored by expert clinician-scientists, fellows will gain hands-on experience and collaborate with healthcare leaders, fostering skills in electronic health records, clinical decision support, and telemedicine.

Confederated Tribes of Siletz Indians

The Confederated Tribes of Siletz Indians is a sovereign nation and has three main branches of government – Judicial, Executive, and Legislative. One of our most important resources is our people.

Education

The Confederated Tribes of Siletz seeks to provide opportunities for Tribal members to reach potential, establish independence and improve quality of life through lifelong learning and education.

Cathern Tufts Memorial Scholarship

Cathern Tufts, affectionately known as “Cat” in the offices of the CTSI administrative offices and Tribal elder woodcuts, was the Tribal Attorney for fourteen and a half years until she passed in 2018 following a short illness. She was a Siletz Tribal member who graduated from Arizona State University School of Law. She served an internship in Washington D.C. prior to going to work as an attorney. Her parents and friends wished to honor her life and achievements through this memorial scholarship. This scholarship is for students in pre-law, law, or in a natural resource field.

The Champions in Action Grant, offered by the Citizens Charitable Foundation, supports nonprofit organizations in California, Massachusetts, New Jersey, New York City, Pennsylvania, Rhode Island, and Southern Florida. This funding, totaling $50,000, aims to empower nonprofits addressing social challenges through innovative solutions. With an application deadline extended to August 22, 2025, eligible organizations can gain not only financial support but also media coverage and volunteer assistance to enhance their community impact.

Don and Bern Holcomb Memorial Scholarship

This scholarship was created in memory of Don and Bern Holcomb and is for high school students from any school in Cattaraugus or Allegany county who plans to attend an accredited post-secondary institution, with a preference for a student majoring in an agricultural or conservation-related field or a female pursuing an engineering degree.

The Alfred P. Sloan Foundation Research Fellowship supports innovative and fundamental research by early-career scientists across various fields. This prestigious two-year fellowship offers $75,000 in a lump sum, allowing recipients to allocate funds towards research-related expenses. Eligible candidates must hold a Ph.D. and be tenure-track faculty at U.S. or Canadian institutions. The fellowship aims to nurture the next generation of leaders in research and academia.

U.S. Small Business Administration

SBA works to ignite change and spark action so small businesses can confidently start, grow, expand, or recover. Created in 1953, the U.S. Small Business Administration (SBA) continues to help small business owners and entrepreneurs pursue the American dream. SBA is the only cabinet-level federal agency fully dedicated to small business and provides counseling, capital, and contracting expertise as the nation’s only go-to resource and voice for small businesses.

Manufacturing grants

SBA provides grants to help empower small manufacturers.

Empower To Grow (E2G) Manufacturing in America Grant

The goal of this grant is to provide workforce development in key manufacturing industries, such as timber, energy, aluminum, steel, digital, and automotive.

SBA is looking for organizations that will provide technical proficiency and essential skills, including operating machinery, quality control, welding, utilizing industrial software, and workplace safety. 

The California Fire Foundation is offering the California Rises 2025 Grant to support California-based fire departments, firefighter associations, tribes, and nonprofits engaged in wildfire relief efforts in Los Angeles and Ventura counties. This grant aims to assist in long-term recovery by funding essential resources for first responders and communities affected by wildfires. Eligible projects include community relief, training, and equipment replacement, with awards ranging from $25,000 to $100,000.

The Audrey Hillman Fisher Foundation Grant aims to enhance health and healing for communities through investments in the arts, education, human services, and environmental initiatives. With a focus on Pittsburgh, PA, Santa Barbara, CA, and Squam Lakes, NH, the foundation accepts grant applications year-round, with deadlines of January 5 for June funding and July 1 for November funding. The foundation prioritizes projects from new organizations within these regions.

The Lakers Youth Foundation offers quarterly grants aimed at empowering underserved youth through education, health, wellness, and sports programs. Grants range from $1,000 to $20,000, and applicants must detail how funds will be utilized. Eligible organizations must have operated for at least two years and cannot exceed 50% of the project's budget in requested funding. The Foundation excludes funding for individuals, private foundations, and new programs.

The AISES RISE Scholarship offers $2,000 annually to support Indigenous students pursuing careers in STEM, particularly in the casino gaming industry. This initiative, powered by Aristocrat Gaming, aims to empower Indigenous talent through exposure, resources, and programming. Eligible applicants must be full-time students and current AISES members, demonstrating a commitment to their education and community. The scholarship seeks to enhance diversity in STEM fields by providing critical financial support to deserving students.

The Stanford Medicine Children’s Health Center for IBD and Celiac Disease offers funding for postdoctoral fellows and instructors to conduct innovative research focused on pediatric IBD and celiac disease. This initiative aims to nurture future researchers and prepare them for independent funding opportunities. Eligible research includes basic, clinical, epidemiological, and health policy studies related to maternal and child health. Funding supports substantial salary and benefits, ensuring commitment to impactful research in this critical area.

The Stanford Children's Health Center for IBD and Celiac Disease offers Intramural Seed Grants to promote innovative research in pediatric diseases. This program supports high-risk, high-reward projects, encouraging multi-PI collaborations across disciplines. Awards of up to $100,000 per year for two years are available, aimed at generating preliminary data for future funding applications. Eligible applicants include Stanford faculty holding specific university positions. Proposals should focus on advancing understanding of pediatric IBD and celiac disease through various research approaches.

The Brennan Family Foundation, established in 1990 by Edward J. Brennan, aims to support charitable, educational, and religious institutions. With a mission to inspire youth development, the foundation provides financial assistance primarily to health care and educational organizations, religious entities, and the arts. Their strategic annual review process ensures that contributions effectively serve our most valuable resource—children. The foundation continues to honor Brennan's legacy of charitable responsibility.

The US Department of Health & Human Services, through the FDA, is funding clinical trials targeting rare neurodegenerative diseases. This initiative aims to enhance treatment options by evaluating the efficacy and safety of new products for both children and adults. By fostering innovative and collaborative trial designs, the FDA seeks to accelerate the approval of new therapies, ultimately benefiting patients with rare conditions and advancing drug development in this critical area.