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Best Operating Grants for Nonprofits in California

Find the perfect Operating grants for nonprofits in California on Instrumentl. 11,000+ Operating grants for nonprofits in California in the United States.

11,000+

Available grants

$3.61B

Total funding

$5K

Median grant

11,000+ grants
$3.61B total
$5K median

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10,803 Results based on applied filters

NIDDK Multi-Purpose Resource-Related, Multi-Component Research Services Centers Cooperative Agreement (U2C - Clinical Trial Optional)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDDK Multi-Purpose Resource-Related Research Centers Cooperative Agreement (U2C) invites applications to enhance research capabilities in areas such as obesity and diabetes. These centers provide specialized services, including technical support and data coordination, primarily to clients at other institutions lacking necessary expertise. This initiative aims to bolster high-impact research through collaboration and experiential training, addressing critical health challenges aligned with NIDDK's mission.
Kidney Diseases

KUH U24 Center Coordinating Hub (U24 Clinical Trial Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The KUH U24 Center Coordinating Hub aims to foster collaboration among funded Centers within the NIDDK/KUHN mission. This initiative encourages the development and sharing of vital research resources, including data, reagents, and expertise, with the broader scientific community. By creating a national network, the program enhances research capabilities and promotes innovative solutions in kidney, urology, and hematology diseases.
Kidney Diseases

KUH P30 Resource Core Center (P30 Clinical Trial Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The KUH P30 Resource Core Center funding opportunity invites applications for centers aimed at enhancing research in Kidney, Urology, and Hematology diseases. These centers will provide essential resources, including data and tools, to the research community, fostering collaboration through a national network with the Center Coordinating Hub. This initiative by the National Institutes of Health aims to drive innovative research and shared expertise for improved health outcomes.
Kidney Diseases

Grady Graves Scholarship Fund

Communities Foundation of Texas
Private
United States
Up to US $20,000
The Grady Graves Scholarship Fund, established in 1953, aims to uplift the community by providing scholarships of up to $20,000 for graduating seniors of Crowell High School in Texas. Focused on enhancing health, wealth, and education, this initiative fosters a culture of giving and equity. By partnering with local donors and organizations, the fund plays a vital role in shaping a brighter future for students and the broader community.
Education - Higher Education Education - High School Academic Scholarship Programs

Advanced Rehabilitation Research Training (ARRT) Program - Health and Function (363965)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $245,000 - US $250,000
The Advanced Rehabilitation Research Training (ARRT) Program, funded by the US HHS: Administration for Community Living, aims to enhance the capabilities of individuals with advanced degrees in conducting high-quality research focused on health and function outcomes for people with disabilities. The program offers advanced training opportunities over a 36-month period, specifically targeting rehabilitation researchers, including those with disabilities, to foster multidisciplinary approaches in disability and rehabilitation research.
Medical Rehabilitation Medical Education & Professional Training Disability Rights & Justice

Women's Initiative for Screening and Health (WISH) (361882)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The Women's Initiative for Screening and Health (WISH) aims to enhance women's health by improving access to preventive services. It focuses on updating HRSA-supported guidelines, increasing awareness of these guidelines, and promoting their adoption in clinical practice. By collaborating with healthcare providers, academic institutions, and patient organizations, WISH strives to implement a comprehensive strategy that benefits women's health across their lifespan.
Women's Health Preventative Healthcare

Diabetes Research Center (P30 Clinical Trial Optional)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is announcing a Notice of Funding Opportunity (NOFO) for Diabetes Research Centers (DRCs). These centers aim to foster collaboration among diabetes researchers, enhance preclinical and clinical research, and provide access to specialized resources. Emphasis is on innovative scientific themes and collaborative projects in areas such as Immunology and Artificial Intelligence. Although applications are not currently solicited, potential applicants are encouraged to prepare for future submissions.
Diabetes

WAEF Scholarships - Danna Gebbers Guzman Memorial

Washington Apple Education Foundation
Private
United States
Unspecified amount
The WAEF Scholarships, supported by the Washington Apple Education Foundation, offer over $1 million in educational awards to more than 300 students this year. These scholarships are primarily for individuals with ties to the tree fruit industry in Washington, with a special focus on the Danna Gebbers Guzman Memorial Scholarship, aimed at nursing students. Eligible recipients can use the funds at accredited institutions with nursing programs.
Agricultural Crops Nursing

Child Well-Being National Program

Doris Duke Foundation Inc.
Private
United States
Unspecified amount
The Child Well-Being Grant Program, established by the Doris Duke Foundation, focuses on promoting the healthy development of children and preventing abuse. With a commitment to addressing systemic inequities, the program supports initiatives that strengthen social service systems and foster partnerships to enhance access to services. It prioritizes funding for projects that encourage community-based interventions and the development of future leaders dedicated to improving child welfare, ensuring all children have the opportunity to thrive in safe and supportive environments.
Child Welfare Services Early Childhood Development Child Abuse & Neglect

Craft Artists Emergency Relief Grant

Craft Emergency Relief Fund Inc
Private
American Samoa, Guam +4 more
US $1,000
The Craft Artists Emergency Relief Grant provides $3,000 to U.S.-based individual craft artists aged 18 and older who are facing recent, unforeseen emergencies. Established by the Craft Emergency Relief Fund (CERF+) in 1985, this grant aims to empower artists during critical times, allowing them to use the funds as needed for recovery. Applications are accepted on a rolling basis, ensuring timely support for artists in distress.
Folk Art / Traditional Art Visual Arts Textile & Fiber Arts

Mary Eliza Mahoney Scholarships

Minnesota Nurses Association Foundation (MNAF)
Association/Society
United States
Up to US $10,000
The Mary Eliza Mahoney Scholarships, offered by the Minnesota Nurses Association Foundation (MNAF), provide financial support to nursing students, members of healthcare unions, their dependents, and veterans. Each scholarship awards $2,500 per semester for a maximum of four semesters, totaling up to $10,000. This initiative aims to enhance nursing education and promote the professional growth of future nurses, ensuring access to quality healthcare for all.
Education - Higher Education Nursing Academic Scholarship Programs

Donald E. Meier Surgical Humanitarian Award

American Pediatric Surgical Association
Association/Society
United States
Unspecified amount
The Donald E. Meier Surgical Humanitarian Award, presented by the American Pediatric Surgical Association, honors a member dedicated to providing surgical care to underserved children without expecting reimbursement. This award recognizes significant humanitarian contributions, whether through local outreach or global missions. Nominations are submitted to the Board, which determines the frequency of the award based on the submissions received. This accolade highlights the commitment of surgeons to humanitarian efforts in the pediatric surgical field.
Children’s Health & Pediatrics Surgery Volunteerism & Philanthropy

OJJDP FY 2026 Second Chance Act Youth Reentry Program

US Department of Justice: Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The OJJDP FY 2026 Second Chance Act Youth Reentry Program aims to provide critical support for moderate- to high-risk youth transitioning back into their communities after confinement. This funding opportunity encourages collaboration among state agencies, local governments, Tribes, and community organizations to deliver comprehensive reentry services and assist youth in overcoming challenges related to recidivism. Applications are due by November 9, 2026, at 8:59 p.m. ET.
Youth Services Crime & Justice Youth Development & Leadership

AISES National Conference Travel Scholarship

American Indian Science and Engineering Society (AISES)
Association/Society
United States
Unspecified amount
The AISES National Conference Travel Scholarship provides financial support for full-time students in STEM fields to attend the annual conference. Covering registration, airfare, and lodging, recipients must commit to attending all events and uphold the AISES Code of Conduct. Selection is based on the quality of essays, letters of recommendation, and academic performance. Announcements for awarded scholarships will be made in late August/early September 2025, facilitating networking and professional development for indigenous students.
Academic Success & Enrichment STEM / STEAM Education Indigenous Services

OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
Up to US $1,200,000
The OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support aims to fortify a national network of 61 multiagency task forces dedicated to combating child sexual exploitation facilitated by technology. This funding opportunity enhances training, prevention, and outreach efforts while fostering collaboration among law enforcement entities. Applications are due in JustGrants by November 9, 2026, at 8:59 p.m. ET, ensuring timely support for critical initiatives to protect children.
Youth Services Crime & Justice Crime Victim Services +1 more

E. Wayne Baumgartle Agricultural Memorial Scholarship

Decatur County Community Foundation Inc.
Private
United States
Unspecified amount
The E. Wayne Baumgartle Agricultural Memorial Scholarship, managed by the Decatur County Community Foundation, aims to support students from Decatur County, Indiana, pursuing post-secondary education in agriculture. This scholarship seeks to alleviate the financial burden of educational expenses for deserving candidates. Interested students are encouraged to reach out to the local FFA instructor for more information. This initiative reflects the foundation's commitment to fostering community growth through educational opportunities.
Academic Scholarship Programs Agricultural Education Education - Higher Education

Mystery Donor Vocational Scholarship Fund

Decatur County Community Foundation Inc.
Private
United States
Unspecified amount
The Mystery Donor Vocational Scholarship Fund, managed by the Decatur County Community Foundation, supports local students accepted into vocational schools. This scholarship aims to assist those pursuing hands-on careers through skill development in various institutions or apprenticeship programs. By easing financial burdens, it encourages students to gain practical experience and contribute to their communities, fostering a skilled workforce for the future.
Academic Scholarship Programs Vocational & Trade Education Education - Higher Education +1 more

Charles H. Adrean D.S.C. Post 625 Memorial Scholarship

The Community Foundation of Herkimer & Oneida Counties
Private
United States
Unspecified amount
The Charles H. Adrean D.S.C. Post 625 Memorial Scholarship, established by American Legion Post 625, honors exceptional athletes graduating from schools within New York's American Legion District 5. This scholarship supports students in their pursuit of post-secondary education, including academic, professional, and trade programs. It remains accessible to recipients entering military service, allowing them to claim it upon returning. The foundation aims to empower youth through educational opportunities that contribute to personal growth and community service.
Education - Higher Education Baseball & Softball Vocational & Trade Education

Bernie G. Yvon Memorial Fund Scholarship

The Community Foundation For Northeast Florida Inc
Private
United States
Up to US $2,000

Community Foundation for Northeast Florida

The Community Foundation for Northeast Florida connects people who care with causes that matter. Since 1964, we have served the citizens of Duval, St. Johns, Nassau, Baker, Clay, and Putnam counties through a range of charitable and civic activities, while helping individual donors achieve their philanthropic goals. We believe in Giving Back. Forever Forward.

Scholarships

Thanks to generous donors, The Community Foundation offers several scholarships each year that benefit students in Northeast Florida who are seeking post-secondary degrees.

Bernie G. Yvon Memorial Fund Scholarship

For High School Seniors & College Students in The Theatre/Performing Arts

The purpose of the fund is to perpetuate the legacy of Bernie G. Yvon by supporting students pursuing study in the Theatre/Performing Arts with need-based scholarships. In this tenth year (2026), amounts up to $2000 each will be available from contributions to the fund via The Community Foundation for Northeast Florida. In selecting the successful candidate(s), the review committee will consider the following:

  • Knowledge of Bernie G. Yvon
  • Theatre/Performing Arts potential and past experiences
  • Financial need
  • Academic record
  • Two letters of recommendation
  • GPA

Education - Higher Education Performing Arts Theater

Leukemia Exploration and Prevention Grant Program (LEAP) - Team Award

American Cancer Society
Association/Society
United States
Up to US $1,720,000
The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention for patients with RUNX1 familial platelet disorder (RUNX1-FPD). This program supports interdisciplinary research teams investigating the mechanisms of leukemogenesis and innovative treatment strategies. With funding of up to $430,000 per year, LEAP encourages projects focused on both understanding clonal evolution and developing novel therapeutic approaches. The initiative seeks to bridge critical knowledge gaps and provide urgent interventions for high-risk populations.
Leukemia

Dennis Jones and Wayne Johnston Memorial Dice Run Scholarship

Cattaraugus Region Community Foundation
Private
United States
Approximately US $500

Dennis Jones and Wayne Johnston Memorial Dice Run Scholarship

This fund provides a scholarship for a graduating senior from either Olean High School or Allegany-Limestone Central School who will be attending a 4-year college, with preference for a student planning to study business or business related field (i.e. accounting, finance, marketing, economics etc.)

Education - Higher Education Career / College Preparation Business Education

Cash for Classrooms Grants

Casey's General Stores, Inc
Private
United States
US $3,000 - US $50,000
Casey's Cash for Classrooms Grants support K-12 public and nonprofit private schools through funding for physical improvements, material needs, teacher support, and community engagement. In 2025, $900,000 was awarded across 80 grants, allowing schools to enhance their learning environments. With a commitment to community engagement, Casey's has donated $15 million since 2019, emphasizing their dedication to making life better for communities and guests. Grants range from $3,000 to $50,000, with funds required to be used within 12 months.
Education - K through 12 Teacher Development & Training Academic Success & Enrichment +1 more

Athene Charitable Foundation Grants

Athene Charitable Foundation
Private
United States
Unspecified amount
The Athene Charitable Foundation focuses on corporate social responsibility through community involvement, aiming to create positive social impacts in education, health, human services, and the environment. Their initiatives include partnerships, employee volunteering, and donations aligned with their mission. They prioritize organizations that support diversity and inclusion while ensuring compliance with their non-discrimination policies. Eligible entities must be registered 501(c)(3) organizations or equivalent, enhancing community welfare where Athene employees live and work.
Education Wellness & Healthy Living Human & Social Services +1 more

Leukemia Exploration and Prevention Grant Program (LEAP) - Research Scholar Grant

American Cancer Society
Association/Society
United States
Up to US $860,000
The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention strategies for patients with RUNX1 familial platelet disorder. This initiative, supported by the American Cancer Society, focuses on understanding the mechanisms behind leukemia development and fostering innovative research leading to effective treatment options. Grants of up to $215,000 per year for four years are available, emphasizing the urgent need for targeted therapies in high-risk populations.
Leukemia

NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32) (358114)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32) supports rigorous biomedical research training and dissertation research for doctoral candidates in clinical, behavioral, or biomedical sciences. Funded by the NIH, this fellowship aims to enhance research capabilities and knowledge in the field of audiology. Key deadlines for applications include April 8, August 8, and December 8 for the years 2025 to 2027, ensuring timely opportunities for aspiring researchers.
Hearing Disorders & Audiology

Vietnam Veteran’s Moving Wall Fund Scholarship

Community Foundation of Central Illinois
Private
United States
US $700

Who We Are

The Community Foundation of Central Illinois will make a sustainable philanthropic impact in our community through visible leadership in connecting people who care with causes that matter.

Vietnam Veteran’s Moving Wall Fund

The Vietnam Veteran’s Moving Wall Fund Scholarship was established to support the children of local veterans who served in the Vietnam War or subsequent conflicts. It was created in 1990 by the Vietnam Veteran’s Moving Wall Committee using remaining funds originally raised to bring the National Vietnam Veteran’s Moving Wall Exhibit to Glen Oak Park in Peoria, Illinois. The exhibit honors the 58,126 Americans who lost their lives during the Vietnam War.

Education - Higher Education Military & Veterans Services Educational Access & Equity

Sandusky Bay Kiwanis Community Services Scholarship

Erie County Community Foundation
Private
United States
Unspecified amount
The Sandusky Bay Kiwanis Community Services Scholarship supports graduating seniors from several high schools in Erie County, Ohio, including Huron, Margaretta, Perkins, Sandusky, and St. Mary’s Central Catholic. To qualify, applicants must have a minimum GPA of 2.8 and demonstrate a commitment to community service and financial need. This scholarship aims to empower students to contribute positively to their communities while furthering their education.
Education - Higher Education Education - High School Academic Scholarship Programs

Operating Grants for Nonprofits in California Highlights

Looking for operating grants for nonprofits in California?


Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in California recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Operating Grants for Nonprofits in California

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

400+ Operating grants for nonprofits in California grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

200+ Operating grants for nonprofits in California over $25K in average grant size

200+ Operating grants for nonprofits in California over $50K in average grant size

38 Operating grants for nonprofits in California supporting general operating expenses

300+ Operating grants for nonprofits in California supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Health & Medicine

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in California?

Most grants are due in the first quarter.

Q1
28.5%
Q2
25.8%
Q3
23.3%
Q4
22.4%

Typical Funding Amounts

What's the typical grant amount funded for Operating Grants for Nonprofits in California?

Grants are most commonly $100,000.

$0 $0 Min.
$100,000 $100 K Median
$2,149,932 $2.1 M Average
$150,000,000 $150 M Max.

Average Grant Size

What's the typical amount funded for California?

Grants are most commonly $145,539.

$145,539

Total Number of Grants

What's the total number of grants in Operating Grants for Nonprofits in California year over year?

In 2024, funders in California awarded a total of 256,564 grants.

2022 237,186

2023 236,635

2024 256,564

Top Grant Focus Areas

Among all the Operating Grants for Nonprofits in California given out in California, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Operating Grants for Nonprofits in California changing over time?

Funding has increased by -1.38%.

2022 $34,364,756,699

2023 $37,770,770,141
9.91%

2024 $37,247,795,891
-1.38%

California Counties That Receive the Most Funding

How does grant funding vary by county?

Los Angeles County, San Francisco County, and San Mateo County receive the most funding.

County Total Grant Funding in 2024
Los Angeles County $10,841,756,858
San Francisco County $5,409,542,294
San Mateo County $5,358,878,304
Santa Clara County $3,811,026,208
Alameda County $3,749,322,182

Related Grants in California

Browse Other Nonprofit Operations & Capacity Grants in California

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