Best Operating Grants for Nonprofits in California

The AAP Foundation Fellowship offers financial support for the Institute for Teaching and Learning in the Health Professions, covering full tuition for its Program for Dental School Faculty. This $3,500 fellowship is designed for periodontists pursuing teaching roles, providing essential skills in academic environments. The program includes comprehensive training, interactive learning methods, and mentorship, enabling participants to successfully transition into educational positions and develop their careers as dental educators.

The Preserve Route 66 Legacy Business Grant Fund offers financial support to enhance historic sites and stimulate economic growth along the iconic Route 66. Targeting projects that reflect the diverse narratives of historically underrepresented communities, this grant emphasizes mural and painting initiatives in preparation for the 2026 centennial celebration. Grants range from $5,000 to $10,000, with no matching funds required, fostering inclusivity and preservation of cultural heritage along the corridor.

The Shakespeare in American Communities Grant, funded by Arts Midwest, supports professional theater companies in the U.S. to produce Shakespeare's works and conduct educational activities. This initiative aims to engage middle and high school students, particularly from underserved communities, through performances and interactive workshops. Eligible applicants must demonstrate experience in theater education and comply with federal regulations. The program emphasizes accessibility, aiming to enrich students' understanding of Shakespeare's relevance in contemporary society.

The Investigators in the Pathogenesis of Infectious Disease Grant Program, funded by the Burroughs Wellcome Fund, aims to support early-career assistant professors studying human infectious diseases. With a budget of $505,000 over five years, it encourages innovative research on the interplay between human systems and infectious agents, fostering multidisciplinary approaches to enhance our understanding of disease mechanisms and health maintenance.

The John and Marlene Heslip Architecture Student Scholarship Program supports full-time undergraduate and graduate architecture students at accredited institutions in the U.S. and Canada. With a focus on innovative design using manufactured concrete masonry and hardscape products, the program awards a $5,000 scholarship each academic year. The scholarship aims to advance the education of future architects while fostering a commitment to excellence and diversity in the field.

The AFAR Grants for Junior Faculty and Glenn Foundation for Medical Research offer up to $160,000 for one- to two-year research projects focusing on the biology of aging. Aimed at early career faculty, these grants support innovative studies not limited to age-related diseases but rather the fundamental mechanisms of aging. Approximately 10 grants will be awarded in 2026, with funding starting July 1. Applicants must be independent investigators within 10 years of their postdoctoral training.

The DoW Traumatic Brain Injury and Psychological Health Translational Research Award aims to transform scientific discoveries into clinical applications. This program encourages innovative research approaches and requires preliminary data. It prohibits basic research and clinical trials, emphasizing the need for relevant animal models or community-based participatory research for human subjects. Funding supports two research levels, refining ideas into tangible products or evaluating them for clinical trials, with options for early-career investigator partnerships.

About Us

Overview

The Alaska Community Foundation connects people who care to the causes that make a difference and matter most to them. We encourage and nurture philanthropy through building and managing permanent endowments, convening stakeholders, working with partners to strengthen Alaskan communities, and providing donors with flexible giving options that are strategic to their philanthropic objectives. ACF also manages the Pick.Click.Give. program.

Mission

Inspiring the spirit of giving and connecting people, organizations, and causes to strengthen Alaska’s communities now and forever.

Vision

ACF envisions an Alaska where communities come together and have resources to thrive.

Healthcare Excellence Scholarship Fund

The Aurora Integrated Oncology Foundation is pleased to offer scholarships to support Alaskan students achieve their fullest potential, with the goal of helping students improve their lives and improve healthcare in their communities.

The NCI Research Specialist Award (R50) supports non-tenure track scientists in cancer research who provide essential contributions within laboratories and core facilities. This award aims to enhance research careers for skilled scientists who do not seek independent investigator funding. Eligible candidates must possess an advanced degree, have at least two years of contribution to NCI-funded research, and dedicate a significant portion of their time to this work. The R50 offers salary support and travel funds to recognize and stabilize these vital roles in cancer research.

The NCI Research Specialist Award (R50) supports clinician scientists involved in NCI-funded clinical trials. This funding opportunity encourages the development of stable research careers by providing salary support and autonomy, allowing clinician scientists to contribute to national clinical trial development and implementation. They play a critical role in sustaining the NCI clinical trials network without serving as principal investigators. This award aims to ensure continuity in cancer research careers.

The FY26 Traumatic Brain Injury and Psychological Health Research Program (TBIPHRP) aims to support impactful health services research that connects research, practice, and policy. It emphasizes building real-world evidence for interventions and clinical guidelines tailored to specific populations. Key features include requirements for clinical trials, preliminary data, and community-based participatory research approaches. The program also offers an Early-Career Investigator Partnering Option to foster collaboration between seasoned and emerging researchers.

The FY26 Traumatic Brain Injury and Psychological Health Research Program's Clinical Trial Award aims to fund impactful clinical trials that address psychological health issues and traumatic brain injury (TBI). This award supports a variety of interventions, requires preliminary data, and mandates community-based participatory research approaches. It offers two research levels: one for pilot studies and early trials, and another for larger, advanced trials assessing effectiveness in relevant populations.

About Us

Overview

The Alaska Community Foundation connects people who care to the causes that make a difference and matter most to them. We encourage and nurture philanthropy through building and managing permanent endowments, convening stakeholders, working with partners to strengthen Alaskan communities, and providing donors with flexible giving options that are strategic to their philanthropic objectives. ACF also manages the Pick.Click.Give. program.

Mission

Inspiring the spirit of giving and connecting people, organizations, and causes to strengthen Alaska’s communities now and forever.

Vision

ACF envisions an Alaska where communities come together and have resources to thrive.

Greater Ketchikan Chamber of Commerce Endowed Scholarship Fund

The mission of the Greater Ketchikan Chamber of Commerce is to advocate and educate on behalf of members to promote a healthy business climate that recognizes both Ketchikan’s quality of life and its economic potential.

Our vision for Ketchikan is a community with a strong and diversified economy, a year-round, stable employment base, and a quality of life which is both attractive to prospective residents and conducive to business expansion and sustainable new development.

For more information about the Greater Ketchikan Chamber of Commerce, please visit their website at https://www.ketchikanchamber.com/

The FY26 Peer Reviewed Cancer Research Program Impact Award promotes significant research aimed at enhancing clinical cancer care. It requires preliminary data to ensure feasibility and emphasizes projects with a strong potential for immediate impact. This funding supports clinical trials and allows for either a single Principal Investigator or a duo of partnering PIs, ensuring that both can contribute distinct aspects of the research. Applications must be carefully coordinated to avoid withdrawal risks.

The DoW Peer Reviewed Cancer Clinical Trial Award supports the rapid initiation of clinical trials aimed at significantly improving cancer treatment. Projects may range from small pilot studies to large-scale phase III trials, focusing on innovative products, drugs, or devices. This award mandates the inclusion of patient advocates and prohibits animal studies, ensuring that all preclinical work is completed prior to the award start date. Regulatory applications must be submitted if required for the proposed trials.

The FY26 Peer Reviewed Cancer Research Program's Idea Award promotes innovative, high-risk cancer research initiatives. It supports groundbreaking concepts that advance cancer knowledge, patient care, and treatment options within the Military Health System. Projects must demonstrate creativity and innovation, avoiding incremental advancements. Notably, the Early Career Investigator Option is available to foster the growth of promising new investigators early in their careers. This award aims to make significant contributions to cancer research for Service Members and Veterans.

This funding opportunity supports exceptionally promising Early Stage Investigators in genomics, encouraging innovative research across various fields such as genomic sciences and medicine. Applicants must submit their proposals by 5:00 PM local time of their organization. The initiative, led by the US Dept. of Health & Human Services through the NIH, aims to foster long-term career development in genomic research while addressing its ethical, legal, and social implications.

The Rella Lossy Award celebrates Rella Lossy’s legacy by recognizing outstanding new full-length plays from emerging playwrights. This award offers $2,500 to the selected playwright and $1,000 to the producing company, supporting the development of fresh voices in theatre. Eligible companies must be based in specific California counties and maintain membership with Theatre Bay Area. This initiative aims to foster new talent and bring diverse narratives to the stage, enriching the cultural landscape of the Bay Area.

Community Foundation of Central Wisconsin

The Community Foundation of Central Wisconsin gives everyone the opportunity to make significant and lasting gifts to their community. We manage over 320 funds that enhance Portage and Waushara counties. Together with our generous donors, we create a strong culture of philanthropy in Central Wisconsin.

We are a tax-exempt, 501(c)(3) public charity founded in 1982 to provide scholarships and grants to organizations and projects that improve the quality of life in Portage and Waushara counties.

Scholarships

The Community Foundation proudly supports students in Portage and Waushara counties with over $325,000 in scholarships annually, thanks to the generosity of local individuals and families. Award amounts range from $500 to $40,000, opening doors to educational opportunities.

Whether you're a student seeking financial support or a donor looking to grow a scholarship fund, we invite you to explore available opportunities and learn how you can be involved.

Don & Mary Hamerski Memorial Scholarship Fund

Qualifications: Graduating High School seniors from a Central Wisconsin high school.

Taos Community Foundation

Taos Community Foundation is dedicated to serving the unique needs of the communities of Taos and western Colfax counties. Our philanthropic efforts support and enrich the lives and opportunities of citizens and protect the environment that sustains us. Our initiatives amplify donor investments, which directly and powerfully support growth in our community.

Edgar Meyer Scholarship

The Edgar F. Meyer Scholarship was established in 2022 by his family. Edgar F. Meyer was a distinguished biochemist, creative scientist and passionate educator who died in 2015. This scholarship is awarded in E.F. Meyer’s memory to students who are planning to study and build a career in the fields of healthcare and /or education and who show creativity, drive, and the ability to overcome hardship in pursuing their dreams.

The scholarship will be available to seniors graduating from Taos County High Schools who plan to pursue advanced studies by attending a 4 year college or university. The Scholarship will also consider those applying to 2 year vocational or trade schools.

The award is up to $4,000 paid out at $1,000 per year for up to 4 years for those students attending a 4 year institution or up to $2,000 paid out at $1,000 per year for 2 years for those students attending a 2 year institution if a 2.5 GPA is maintained and all other requirements are met.

The NIDCR Predoctoral to Postdoctoral Transition Award aims to enhance the diversity of the dental, oral, and craniofacial research workforce. This program supports exceptional graduate students from underrepresented backgrounds as they transition from PhD or dual degree programs (F99) to mentored postdoctoral positions (K00). Key deadlines for applications span from August 2024 to April 2027, ensuring ample opportunities for eligible candidates to apply.

The Koshland Young Leader Awards, established in 1999 by Dr. Daniel Koshland Jr., recognize young leaders facing significant challenges while demonstrating academic excellence and community leadership. Each year, 11 juniors from the San Francisco Unified School District receive $10,000 for educational expenses. This program has awarded nearly $1 million to over 170 students, empowering them to pursue higher education despite adversities such as economic hardship and family responsibilities.

The Junior Faculty Development Award, funded by the American College of Gastroenterology, offers $450,000 over three years to support junior researchers in gastroenterology or hepatology. Aimed at ACG members, this award allows recipients to dedicate 50% of their time to clinical research, enhancing their skills and advancing their careers. Eligible candidates include those within seven years post-fellowship who can guarantee protected research time. The initiative fosters novel research that directly impacts gastrointestinal health.

Washington County Community Foundation

The Washington County Community Foundation seeks to improve the quality of life in Washington County by promoting and facilitating philanthropy. We accomplish this by assuming four philanthropic roles of Grantmaker, Donor Service Organization, Fundraiser, and Community Leader. Fostering philanthropy by offering charitable gifting opportunities to donors on an individualized basis and at reasonable fees, we make charitable giving easier, more satisfying, and more effective. 

The Foundation is a tax-exempt, 501(c)(3) not-for-profit corporation organized under the laws of Pennsylvania, which is registered with the Pennsylvania Charities Bureau and annually files the Federal Form 990.

Scholarships for Post-Secondary (Undergraduate) School

The Foundation provides both need-based and merit-based scholarships to students in Washington County, with a few scholarships also available to students in Greene County. All scholarships are made payable to the educational institution the student is attending. 

Chapman Family Scholarship Fund

For current year graduating seniors of any Washington County or Greene County high school who demonstrate financial need. Preference will be given to certificate, trade, or technical school applicants. Awardees may be eligible for up to three subsequent-year scholarships, provided they maintain eligibility.

The SPFFA Educational Scholarship provides financial support of $5000 for university candidates aiming to teach French in primary and secondary schools. To be eligible, applicants must be American citizens or resident aliens, preferably enrolled in a School of Education and pursuing a Master in Teaching with a focus on French. Additionally, applicants need to maintain a GPA above 3.00, ensuring commitment to their educational goals.

Washington County Community Foundation

The Washington County Community Foundation seeks to improve the quality of life in Washington County by promoting and facilitating philanthropy. We accomplish this by assuming four philanthropic roles of Grantmaker, Donor Service Organization, Fundraiser, and Community Leader. Fostering philanthropy by offering charitable gifting opportunities to donors on an individualized basis and at reasonable fees, we make charitable giving easier, more satisfying, and more effective. 

The Foundation is a tax-exempt, 501(c)(3) not-for-profit corporation organized under the laws of Pennsylvania, which is registered with the Pennsylvania Charities Bureau and annually files the Federal Form 990.

Scholarships for Post-Secondary (Undergraduate) School

The Foundation provides both need-based and merit-based scholarships to students in Washington County, with a few scholarships also available to students in Greene County. All scholarships are made payable to the educational institution the student is attending. 

George and Mary Matijevich Scholarship Fund

For a current year graduating senior from Burgettstown High School, Avella High School, or Fort Cherry High School, who demonstrates financial need and is pursuing post-secondary education in electronics, mechanics, mechatronics, machine tool technology or a related field. 

Scholarship Opportunities

The Sioux Falls Area Community Foundation manages one of the state's largest scholarship programs, awarding more than $500,000 in scholarships to local students each year. If you’re interested in pursuing higher education, it's likely we have a scholarship that can help you achieve your dream.

Trent Area Scholarship

Organizers have defined the Trent community as the area bounded on the south by the Moody County line, on the north by SD Highway 34, on the east by the South Dakota state line, and on the west by the Colman Road, also known as 470th Avenue.

* Multiple scholarships are awarded