Best Detroit Grants for Nonprofits in Michigan

The NIH is set to release a Notice of Funding Opportunity for early to definitive clinical trials across various biomedical fields. This initiative focuses on trials evaluating drugs, devices, and interventions that align with NIH's mission. Utilizing the R61/R33 funding mechanism, projects can span up to 7 years, supporting both planning and trial phases. Interested investigators are encouraged to prepare collaborative proposals, although applications are not currently being solicited.

Across the United States, small and micro businesses (SMBs) play a critical role in driving economic opportunity, job creation, and community prosperity. Yet many entrepreneurs continue to face challenges accessing the training, resources, and support needed to grow and remain competitive in an evolving economy. To help address these needs, Visa Foundation is committing $2M to launch an open-call grant program that will support nonprofit Entrepreneurial Support Organizations (ESOs) that provide direct services to SMBs. Through this program, Visa Foundation aims to strengthen the capacity of high-impact organizations that help small businesses build greater resilience, expand economic opportunity, and contribute to thriving local economies. 

The National Institute of Allergy and Infectious Diseases (NIAID) aims to enhance the development of diagnostic tests for infectious diseases through strategic partnerships between academia and industry. By fostering collaborations, NIAID seeks to overcome barriers to commercialization, ensuring promising diagnostics reach the market effectively. This initiative aligns with NIH's mission to advance innovative technologies that improve treatment and prevention strategies for infectious diseases, ultimately contributing to public health advancements.

About

Originally conceived by Dr Bruce Mesara in 1990 as a means to carry on his philanthropic efforts beyond his lifetime, the Mesara Family Foundation was re-envisioned by his two children Amy and Douglas in 2014, and received their 501(c)(3) status from the IRS in 2015. Amy and Douglas sought out the assistance of their cousins to build upon the charitable principals on their parents, aunts and uncles.

The foundation is headquartered in Kalamazoo Michigan.

Mission

The mission of the Mesara Family Foundation is to honor the philanthropic principles of the Mesara and Pauch families by supporting carefully selected organizations that share similar values. Our focus is to provide support toward education, conservation and other causes of special family interest where our funding will make a genuine difference.

The BJA FY 2026 John R. Justice Formula Grant Program offers loan repayment assistance to local and state prosecutors and public defenders who commit to three years of service. Administered by state agencies, this program aims to alleviate the financial burden on legal professionals dedicated to public service. Applications are due by November 10, 2026, providing a crucial opportunity for eligible beneficiaries to secure support for their educational loans.

The National Oceanic and Atmospheric Administration (NOAA) is inviting proposals for projects that enhance coastal flood protection through public-private partnerships, innovative insurance products, and improved sediment management. This initiative aims to utilize natural infrastructure to bolster flood preparedness and resilience. Funding of up to $2,000,000 is available for selected projects, supporting research teams that collaborate with regional stakeholders. Proposals must be submitted via Grants.gov, ensuring accessibility to critical resources and information.

The BJA FY 2026 Tribal Justice Training and Technical Assistance Program aims to enhance Tribal justice systems through specialized technical support. This funding opportunity addresses critical issues such as violent crime and substance-use related crime, including opioids. By assisting federally recognized Indian Tribes, the program promotes the development of sustainable legal and corrections infrastructure while fostering collaboration with federal, state, and local partners. Applications are due by October 28, 2026, at 8:59 p.m. ET.

The OJJDP FY 2026 Second Chance Act Youth Reentry Program aims to provide critical support for moderate- to high-risk youth transitioning back into their communities after confinement. This funding opportunity encourages collaboration among state agencies, local governments, Tribes, and community organizations to deliver comprehensive reentry services and assist youth in overcoming challenges related to recidivism. Applications are due by November 9, 2026, at 8:59 p.m. ET.

The OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support aims to fortify a national network of 61 multiagency task forces dedicated to combating child sexual exploitation facilitated by technology. This funding opportunity enhances training, prevention, and outreach efforts while fostering collaboration among law enforcement entities. Applications are due in JustGrants by November 9, 2026, at 8:59 p.m. ET, ensuring timely support for critical initiatives to protect children.

The CDC is offering funding to enhance collaboration among tuberculosis control programs and various partners in the U.S. This initiative aims to strengthen relationships with national TB control entities, federal agencies, academia, and community organizations. The goal is to promote health and quality of life by preventing, controlling, and eventually eliminating tuberculosis in the United States, building on previous funding opportunities.

The Advanced Rehabilitation Research Training (ARRT) Program aims to enhance the research capabilities of individuals with advanced degrees, focusing on disability and rehabilitation research related to employment outcomes. Funded by the US HHS Administration for Community Living, this grant offers a 36-month project period, supporting multidisciplinary training for researchers, including those with disabilities, to contribute to high-quality research in the field.

The Advanced Rehabilitation Research Training (ARRT) Program, funded by the US HHS: Administration for Community Living, aims to enhance the capabilities of individuals with advanced degrees in conducting high-quality research focused on health and function outcomes for people with disabilities. The program offers advanced training opportunities over a 36-month period, specifically targeting rehabilitation researchers, including those with disabilities, to foster multidisciplinary approaches in disability and rehabilitation research.

The Small Business Innovation Research Program (SBIR) Phase II aims to enhance technological innovation in the private sector, focusing on improving the lives of individuals with disabilities through research and development. Administered by the US HHS Administration for Community Living, this program supports small businesses in addressing the needs of these individuals. Grants are available for a 24-month project period, allowing projects to expand upon Phase I results to achieve greater commercial application and societal impact.

The Small Business Innovation Research (SBIR) program, Phase I, aims to stimulate technological innovation in the private sector, enhancing the role of small businesses in meeting Federal research needs. Specifically, ACL's SBIR program focuses on improving the lives of individuals with disabilities through research and development products. The initiative includes 11 grants with a 6-month project period to assess the feasibility of innovative concepts, contributing to economic and social benefits.

The Advanced Rehabilitation Research Training (ARRT) Program, funded by the US HHS: Administration for Community Living, aims to enhance the skills of researchers in the field of disability and rehabilitation. By providing advanced training over a three-year period, this program focuses on improving community living and participation outcomes for individuals with disabilities. It seeks to equip scholars with the necessary tools to conduct high-quality, multidisciplinary research, ultimately benefiting the disability community.

The Alzheimer's Disease Programs Initiative (ADPI) aims to foster the development of dementia-capable community health worker programs within the National Aging Network. This initiative, supported by the US HHS: Administration for Community Living (ACL), seeks to enhance dementia screening, reduce barriers to care, and improve access to essential services for individuals with dementia and their caregivers. By integrating community health workers into aging services, the program aspires to elevate the quality of life for those affected.

The Rehabilitation Engineering Research Center on Recreational, Sport, and Exercise Technologies for People with Disabilities aims to enhance rehabilitation services through innovative technological solutions. This initiative focuses on promoting health and exercise among individuals with disabilities by addressing unique rehabilitation challenges. Funded by the US HHS Administration for Community Living, the project spans 60 months, involving advanced research and development to create effective support mechanisms and overcome environmental barriers.

The Field Initiated Projects Program aims to foster new research and develop solutions that enhance the inclusion and independence of individuals with disabilities. This initiative focuses on generating scientific knowledge and understanding critical issues faced by these populations, particularly those with significant support needs. With a total of 16 grants available over a 36-month period, this program encourages innovative approaches that support employment, living arrangements, and caregiver involvement.

The Rehabilitation Research and Training Center (RRTC) focuses on enhancing the lives of parents with disabilities through research, training, and technical assistance. This initiative aims to develop evidence-based services and supports that empower parents in their caregiving roles. Funded by the US HHS: Administration for Community Living (ACL), the project spans 60 months with a commitment to fostering inclusive environments for families. The RRTC will explore innovative interventions and technologies to better support these parents in their daily challenges.

The Rehabilitation Engineering Research Center aims to enhance services for individuals who are blind or have low vision through innovative technology development. This initiative focuses on overcoming rehabilitation challenges and environmental barriers, promoting independence and community living. A grant of five years will support ongoing research efforts, ensuring advancements in assistive technologies that empower the target population. The project aligns with the Rehabilitation Act's goals, emphasizing the importance of accessibility and inclusion.

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Awards

Mensa Foundation Prize

The Mensa Foundation Prize celebrates exceptional achievements that redefine our understanding of intelligence and creativity.

Awarded biennially, this distinguished honor highlights transformative scientific discoveries that elevate the understanding of intelligence.

Details

One of the most prestigious honors in the field, the Mensa Foundation Prize highlights exceptional contributions that elevate the understanding of intelligence.

Award Components

Criteria for Entry

The NASA ROSES 2025: A.18 Geosphere program provides funding for research on solid-Earth processes across various scales. It aims to enhance understanding of the Earth's structure and dynamics, particularly in the core, mantle, and lithosphere. Key areas of focus include Earth Surface Properties, Crustal Dynamics, and Earth Interior. This initiative supports advancements in managing natural resources, assessing geohazards, and exploring the forces driving plate tectonics, ultimately contributing to improved hazard forecasting and mitigation strategies.

The Distressed Cities Technical Assistance (DCTA) Program provides competitive funding for eligible applicants to deliver technical assistance to local governments serving economically distressed communities of 50,000 or fewer residents. Selected awardees collaborate closely with HUD to enhance the capabilities of UGLG officials and staff, ensuring they effectively address community needs. Applicants may focus on broad HUD jurisdictions or specific areas as specified in the program's NOFO.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5430 - Unlocking Value and Opportunities from Carbon Flows in Water Utilities

Grant Information

• Identify carbon flows across drinking water, stormwater, wastewater, and advanced treatment systems. Carbon flows may include source water, stormwater, process emissions, process inputs, residuals, and biogas.
• Identify the most relevant carbon recovery, capture, conversion, storage, and avoidance opportunities.
• Evaluate value creation pathways, including products, avoided costs, and environmental attributes, and mechanisms and partnerships needed to put them into practice.
• Assess how opportunities vary across system types and local contexts by focusing on more common scenarios for utilities.
• Provide practical, research-based insights to support identification, prioritization, evaluation, and advancement of carbon management opportunities under site-specific conditions and constraints.
• Evaluate implications for greenhouse gas (GHG) accounting, environmental attribute claims, and other potential benefits across pathways.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5411 - Practical Playbook for Adaptive Utility Capital Improvement Planning Under Deep Uncertainty

Grant Information

• Assess current utility practices for incorporating adaptive or flexible decision making into capital improvement planning (CIP) at the portfolio or programmatic level.
• Identify where deep uncertainty most affects CIP decision points, including investment areas prone to lock-in or points of no return.
• Document the institutional processes, frameworks, and governance structures that have enabled utilities to embed adaptive and flexible investment strategies.
• Quantify how adaptive capital strategies compare to traditional CIP approaches in terms of lifecycle costs, rate stability, financial risk exposure, and avoided or deferred capital investments across a range of plausible future conditions.
• Establish practical criteria to help utilities determine which types of capital investments are well suited for adaptive approaches.
• Develop a practitioner-focused playbook that equips utilities to apply adaptive CIP in practice, including case studies, decision trees, trigger points, vulnerability assessment tools, financial and risk insights, and governance guidance.
• Produce tiered recommendations that allow utilities to adopt adaptive CIP practices incrementally.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5418 - Optimizing PFAS Treatment Systems for Multi-contaminant Removal and Operational Benefits

Project Objectives

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5426 - Investigation of Non-Point Sources of PFAS in Sewersheds and Potential Mitigation Strategies

Grant Information

Evaluate the impact of non-point or dispersed sources of per- and polyfluoroalkyl substances (PFAS) in the sewershed (including PFAS-contaminated groundwater infiltration) on PFAS mass loading to wastewater treatment plants.

Assess how PFAS loading from non-point or dispersed sources of PFAS in the sewershed may affect treatment efficiency and reuse water quality.

Improve understanding of PFAS precursor contributions.

Identify potential strategies to mitigate PFAS loading from non-point or disbursed sources of PFAS in the sewershed.