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Best Detroit Grants for Nonprofits in Michigan

Discover active funding opportunities in Detroit Grants for Nonprofits. 37,000+ grants are available for a wide range of missions and programs with additional grants in Grand Rapids, Ann Arbor, and Lansing.

9,000+

Available grants

$2.60B

Total funding

$5K

Median grant

9,000+ grants
$2.60B total
$5K median

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9,419 Results based on applied filters

Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Enrollment Hubs

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institutes of Health (NIH) is dedicated to advancing emergency care through the Strategies to Innovate Emergency Care Clinical Trials Network (SIREN). This initiative seeks to establish clinical enrollment hubs that will enhance the network's ability to conduct trials aimed at improving outcomes for patients experiencing neurological and cardiovascular emergencies. Although applications are not currently being accepted, this notice encourages potential applicants to prepare collaborative and impactful proposals.
Health & Medicine Cardiovascular Diseases & Systems Neurological Diseases & Disorders +1 more

Established Clinician Investigator Award to Support Mentoring (KS1)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Established Clinician Investigator Award to Support Mentoring (KS1) is designed to provide established clinician investigators with dedicated time for mentoring early-career clinician research scientists. This initiative by the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to enhance the quality of mentorship, fostering the development of future leaders in clinical research. It supports a sustained commitment to training and guidance, ensuring a robust pipeline of skilled professionals.
Medical Education & Professional Training Tutoring & Mentoring

Mentored Career Transition Award (KT1/R00)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Mentored Career Transition Award (KT1/R00) offers a biphasic funding opportunity for up to 5 years, supporting the transition of postdoctoral researchers to independent faculty positions. The first phase provides 1-2 years of mentored career development, while the second phase grants up to 3 years of independent research support, contingent upon satisfactory progress and faculty appointment. This grant aims to enhance the capacity of early-career researchers in achieving research-intensive roles.
Education - Higher Education Tutoring & Mentoring

Mentored Clinician Research Scientist Career Development Award (KC1)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Mentored Clinician Research Scientist Career Development Award (KC1) from the NIH supports clinician research scientists for up to five years, providing dedicated time for intensive research career development. This award aims to guide candidates with clinical doctoral degrees towards achieving research independence by pairing them with experienced mentors who can help navigate their career paths.
Education - Higher Education Tutoring & Mentoring

Mentored Research Scientist Career Development Award (KR1)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Mentored Research Scientist Career Development Award (KR1) offers crucial support for researchers aiming for independence. Funded by the US Dept. of Health & Human Services through the NIH, this award allows candidates to engage in intensive research training under a mentor's guidance for up to five years. It is designed for those with research doctoral degrees, facilitating their transition into independent research roles and enhancing their contributions to the scientific community.
Education - Higher Education Tutoring & Mentoring

Rural Health Network Development Planning Program (363581)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
The Rural Health Network Development Planning Program aims to enhance rural health care by fostering integrated health care networks. It focuses on collaboration among entities to bolster local capacity and improve care coordination in underserved areas. By achieving efficiencies and expanding access to essential services, the program seeks to strengthen the overall rural health system while promoting the use of health information technology and exploring innovative care delivery models.
Rural Health Care Health Care Access & Delivery

Rural Health Network Development Program (363580)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $500,000
The Rural Health Network Development Program aims to enhance health care access in rural areas by supporting integrated health care networks. It offers two funding tracts: the Network Advancement Tract for established networks to overcome operational barriers and the Network Development Tract for early-stage networks to plan and expand services. Both tracts focus on improving care coordination, health outcomes, and operational efficiency, thereby strengthening the rural health care system.
Rural Health Care Health Care Access & Delivery

Rural Maternity and Obstetrics Management Strategies Program (363582)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The Rural Maternity and Obstetrics Management Strategies Program (Rural MOMS) aims to enhance access to maternity and obstetrics care in rural areas through collaborative networks. Funded by the US HHS: Health Resources & Services Administration (HRSA), this initiative focuses on innovative strategies to improve healthcare delivery for mothers and infants in underserved regions, ensuring that quality care is accessible where it is needed most.
Reproductive Health Women's Health Maternal And Perinatal Health +1 more

Radiation Exposure Screening and Education Program

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
US $250,000 - US $500,000
The Radiation Exposure Screening and Education Program aims to support organizations in their efforts to screen and educate individuals who have been exposed to radiation from uranium mining and U.S. nuclear weapons testing. This initiative emphasizes the importance of awareness and education in mitigating health risks associated with radiation exposure, ensuring affected communities receive the necessary resources and support for health management.
Environmental Contamination & Pollution Community / Public Safety

Lions Club International Hunger Grant Program

Lions Clubs International Ftdn
Private
United States
US $10,000 - US $150,000

About Lions Club International FoundationLions Clubs International Foundation (LCIF) provides grants that empower the service of our members. Since its inception in 1968, LCIF has awarded more than US$1.3 billion in grant funding.  Mission :Our mission is to empower Lions clubs, volunteers and partners to improve health and wellbeing, strengthen communities, and support those in need through humanitarian service and grants that impact lives globally, and encourage peace and international understanding. And we fulfill it every day, everywhere we serve.Lions Club International Hunger Grant ProgramHunger Grants focus on strengthening infrastructure and providing essential equipment for Lions’ hunger-relief efforts. These grants empower Lions to support vital initiatives such as school feeding programs, food banks and feeding centers, ensuring that those in need receive the nourishment they require. These grants support infrastructure and equipment acquisition for Lions’ projects focused on alleviating hunger.Grant Examples: 

  • Construction or expansion of food banks, feeding centers and food storage facilities.
  • Purchase of refrigerators and freezers to store perishable food items.
  • Vehicles to transport, collect and deliver food.

Food Access & Hunger Food Security

Annual Recurring University Training and Research

United States Department of Energy (DOE)
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The Annual Recurring University Training and Research grant aims to foster the next generation of engineers and scientists by funding research and development at U.S. colleges and universities. This initiative focuses on supporting early-stage research and enhancing opportunities for underrepresented communities, ensuring that students gain essential skills for successful careers in the U.S. workforce and economy. It is a vital step toward inclusive educational advancement and workforce development.
Workforce Preparation & Job Readiness Energy Engineering +2 more

Capacity Building for Global, Regional, and National Immunization Programs (363591)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Capacity Building for Global, Regional, and National Immunization Programs aims to enhance immunization efforts in key countries, focusing on the prevention and control of vaccine-preventable diseases like polio and measles. By strengthening immunization services and surveillance systems, the program will better address emerging health threats and reach under-immunized populations. Additionally, it will support sustainable practices through National Immunization Technical Advisory Groups and manage the National Stop Transmission of Polio program in Pakistan.
Preventative Healthcare Vaccines & Immunizations

Promoting Population Health through Increased Capacity in Alcohol Epidemiology & the Prevention of Excessive Alcohol Use

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The CDC has announced funding for FY 2027 to enhance state capacity in alcohol epidemiology and prevent excessive alcohol use through the NOFO CDC-RFA-DP-27-0072. This initiative aims to equip states with essential tools and knowledge for effective public health measures against excessive alcohol use, a major preventable cause of death in the U.S. The program will also provide expert technical assistance and training on effective prevention strategies over a 5-year performance period.
Epidemiology & Public Health Addiction & Substance Use Disorders Preventative Healthcare

Rural Communities Opioid Response Program - Community Systems Development

Health Resources and Services Administration
Federal Government
American Samoa, Guam +7 more
Up to US $500,000
The Rural Communities Opioid Response Program (RCORP) - Community Systems Development aims to enhance behavioral health systems in rural areas by providing funding for the development and expansion of services. This initiative supports the establishment of formalized networks to boost operational and clinical capacity, ensuring effective implementation of evidence-based substance use disorder prevention, treatment, and recovery services tailored to community needs.
Rural Development Rural Health Care Community Services +1 more

Rural Communities Opioid Response Program - Evaluation

Health Resources and Services Administration
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The Rural Communities Opioid Response Program - Evaluation aims to assess the effectiveness of behavioral health strategies in rural settings. By developing evaluation tools and resources, this initiative seeks to empower local communities in their health initiatives, ensuring that future programs are informed by comprehensive evaluations. Funded by the Health Resources and Services Administration, the program highlights the importance of tailored approaches to address opioid-related challenges in rural areas.
Mental Health & Psychiatric Diseases Addiction & Substance Use Disorders Rural Development +1 more

RNomics Molecular Standards

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The RNomics Molecular Standards initiative, supported by the NIH Common Fund, aims to enhance research on RNA molecules by developing standardized references. This program will facilitate the creation, testing, and distribution of RNA molecular reference standards, which are crucial for ensuring consistency and reliability in RNA research. By providing guidance on best practices and planning for long-term availability, RNomics will help advance technologies that analyze RNA sequences and functions, ultimately improving health and disease understanding.
Genetics & Genomics Human Genome & Genetics

Transformative Technologies for Experimental and Computational RNome Characterization and Functional Analysis

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $500,000
The NIH Common Fund is launching the RNomics program to advance RNA research through innovative technologies. This initiative focuses on developing tools for comprehensive analysis of RNA molecules, addressing current methodological limitations. Key priorities include sequencing RNA, detecting modifications, and studying RNA function across various biological contexts. The program encourages high-risk, early-stage projects that demonstrate potential for significant impact. Successful Phase 1 projects may transition to Phase 2, aimed at delivering validated resources for the research community.
Genetics & Genomics Human Genome & Genetics

Cech Fellows Program

Howard Hughes Medical Institute
Private
United States
Up to US $15,000

Howard Hughes Medical Institute

More than 70 years ago, the Howard Hughes Medical Institute (HHMI) was founded with a mission to advance basic biomedical research and science education. Today, we invest in exceptional scientists at all career stages, catalyzing breakthroughs, new technologies, and the next generation of transformative clinical therapies. Our pathbreaking science takes place at more than 60 host institutions across the US, and at our Janelia Research Campus.

Cech Fellows Program

The Cech Fellows Program is a paid, nine-week summer research experience for rising college juniors and seniors designed to empower the next generation of scientific leaders through mentorship, hands-on research, and community. 

The Cech Fellows Program gives undergraduate students in the life sciences the opportunity to conduct hands-on research with leading scientists at HHMI laboratories across the US, from universities and research institutions to HHMI’s Janelia Research Campus outside of Washington, DC. Students are matched with HHMI scientists conducting fundamental research that advances our understanding of biology and health. 

This immersive program gives students the chance to contribute to real scientific discovery, receive professional mentorship, explore potential careers in biological and biomedical research, and connect with a community of like-minded peers.  

Gain Hands-On Experience in Research & Lab Work

The HHMI Cech Fellows Program is a 9-week, full-time, immersive research experience running from June 14, 2027 to August 12, 2027. Fellows: 

  • conduct cutting-edge basic research in an HHMI lab for their own educational benefit  
  • participate in professional development workshops   
  • engage with a vibrant scientific community  
  • build essential skills for future success in a scientific career   

Funding & Logistics 

As a Cech Fellow, students:  

  • receive a $15,000 stipend if placed in an HHMI lab at a host institution, intended to cover travel, housing, meals, and incidentals. (Students are responsible for arranging their own housing.) 
  • receive a $12,000 stipend if placed at HHMI’s Janelia Research Campus. (Students placed at Janelia have access to free, on-campus housing.)
  • participate in an end-of-summer symposium at the Janelia Research Campus in Ashburn, VA, from August 10–12, 2027, at which they present their research and meet other Cech Fellows from across the country. Food, lodging, and travel to and from the symposium are provided by HHMI. 
  • are matched with a local contact from their host lab who will provide suggestions for local housing options. Students are expected to travel to arrive at their host institutions by June 14, 2027.  
Education - Higher Education Science Biology +3 more

PSE Solar Grant

Puget Sound Energy
Corporate
United States
Up to US $100,000

Puget Sound Energy (PSE)’s Solar Grants are funding to increase equitable access to the benefits of solar. In 2026, PSE is offering $1,000,000 in competitive funding awards to community-based organizations, government agencies and Tribal entities in PSE’s electric service area to install solar at their property.What makes a solar project eligible?

  • Proposed projects must receive sufficient sunlight, as determined by a solar installer. The total solar resource fraction (TSRF) must be at least a 75% average of all points in the proposed solar array.
  • Property that solar arrays are installed on may be owned or leased. If the property is leased, the applicant must demonstrate project support from the property owner and affirm that they will be in that space for at least five years.
  • Projects must be less than or equal to 100 kW AC in size and will apply for interconnection and Net Metering.
  • Grantees must maintain insurance coverage of the solar system for a minimum of five years, and PSE recommends maintaining insurance for the life of the system.
  • Grantees must retain Renewable Energy Certificates (RECs) for the life of the project or sell them to PSE. RECs are a market-based instrument that represent the non-power, “green” attributes of renewable electricity generation. Grantees comply simply by not selling these attributes to any entity other than PSE.
  • Solar is a long term investment. The roof or structure this array is being placed on should be in good condition and should not need to be replaced for at least 20 years.
Solar Energy

Hope for Addiction Scholarship

Samba Recovery
Corporate
United States
US $1,000

About Samba RecoverySamba Recovery is dedicated to empowering individuals recovering from alcoholism and drug addiction by restoring confidence and fostering resilience. Through a foundation of compassion, support, and holistic care, we guide individuals toward renewed health and wellness, meaningful relationships, and the discovery of their inner strengths—assisting them to achieve their fullest potential.Hope for Addiction ScholarshipSamba Recovery’s Hope for Addiction Scholarship is an annual $1,000 award dedicated to encouraging more young people to join the fight against addiction by pursuing degrees that directly support individuals and families affected by substance use disorders.

We welcome applications from all eligible students, with special encouragement for those who are in recovery themselves or who have been impacted by addiction within their families.Application requirements:

  • Proof of college enrollment or acceptance
  • Pursuing a degree with the goal of working with individuals and/or families impacted by addiction
  • Completed application form
  • An original 500 to 1000 word essay on how you are planning to use your degree to help individuals and families struggling with addiction, and why helping those affected by substance use disorder is important to you
Addiction & Substance Use Disorders Alcoholism

Patient Education Grants

Revolution Medicines
Corporate
Europe, United States
Unspecified amount

We are Revolutionaries

Who We Are

We are Revolutionaries -passionate in our singular pursuit of discovering, developing and delivering innovative targeted therapies for patients living with RAS-addicted cancer. At Revolution Medicines, we believe in challenging the status quo to find new therapeutic approaches to some of the toughest cancers. With our first wave of investigational RAS(ON) inhibitors, we are pioneering a new way of targeting the RAS cancer drivers of disease, and we have the potential to change the treatment paradigm in these cancers where there is a significant unmet medical need.

Our mission is to revolutionize treatment for patients with RAS-addicted cancers through the discovery, development and delivery of innovative, targeted medicines.

Research, Grants & Support

At Revolution Medicines, we understand the importance of extending our support of scientific advancement beyond the research we conduct and the medicines we provide.

We support activities that make meaningful information and resources available to the broader medical and scientific communities to help advance science, increase understanding of certain diseases, and enhance patient care.

Charitable Donations

Funding for programs that deliver disease awareness, treatment education, or other healthcare information intended to improve patient understanding and empowerment.

Patient Care & Services Community Health Education Cancer / Oncology

Joseph G. Markoly Foundation Grant Support for Elder Organizations

Joseph G Markoly Foundation Inc
Private
Brevard County, Florida, DeSoto County, Florida +12 more
Unspecified amount

Joseph G Markoly Foundation Inc

When Joseph Markoly originally established the foundation more than thirty years ago, its focus was on Alzheimer’s and heart disease support, funded through a number of the larger national disease-related organizations. Over time the focus has shifted to helping small to mid-size organizations in our local communities which support children and seniors in a variety of effective ways. 

Markoly Foundation was established in honor of Joseph G. Markoly, an entrepreneur and philanthropist who wanted to make a positive impact in people’s lives. Joseph’s family was affected directly by both Alzheimer’s and heart disease having lost a family member to each condition. For that reason, the foundation dedicates a majority of their resources to providing grants to organizations that focus on the treatment of each of these diseases. In addition, Markoly Foundation supports a variety of programs dedicated to helping children and seniors by providing services, supplies, programs and research in areas impacting these demographics.

Joseph G. Markoly Foundation Grant Support for Elder Organizations

The Markoly Foundation takes pride in supporting local organizations that provide services for elders in our community. Seniors face a number of challenges that come with aging, especially when they don’t have loved ones who are able to assist them with their needs. We provide grants for a variety of senior-related programs from Caregiver Education and Support to Emergency Meal Delivery and Transportation Services.

We are dedicated to providing funding for local nonprofit programs that improve the quality of life for all, but particularly for the children and elders in our community.

Senior Services Caregiver Support / Respite Care Food Delivery & Distribution Services +1 more

Joseph G. Markoly Foundation Grant Support for Children’s Organizations

Joseph G Markoly Foundation Inc
Private
United States
Unspecified amount

Joseph G Markoly Foundation Inc

When Joseph Markoly originally established the foundation more than thirty years ago, its focus was on Alzheimer’s and heart disease support, funded through a number of the larger national disease-related organizations. Over time the focus has shifted to helping small to mid-size organizations in our local communities which support children and seniors in a variety of effective ways. 

Markoly Foundation was established in honor of Joseph G. Markoly, an entrepreneur and philanthropist who wanted to make a positive impact in people’s lives. Joseph’s family was affected directly by both Alzheimer’s and heart disease having lost a family member to each condition. For that reason, the foundation dedicates a majority of their resources to providing grants to organizations that focus on the treatment of each of these diseases. In addition, Markoly Foundation supports a variety of programs dedicated to helping children and seniors by providing services, supplies, programs and research in areas impacting these demographics.

Joseph G. Markoly Foundation Grant Support for Children’s Organizations

Children are the future of this world and the Markoly Foundation is proud to fund local programs dedicated to improving the lives of children and their families. From providing vision services for school kids to classes on parenting, we are proud to do our part to help fund critical community programs for families.

We are dedicated to providing funding for local nonprofit programs that improve the quality of life for all, but particularly for the children and elders in our community.

Family Services Child Welfare Services Child Care Services

U.S. National Science Foundation State and Regional Artificial Intelligence Infrastructure Hubs:

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NSF State and Regional AI Infrastructure Hubs program seeks to enhance access to computational resources essential for AI-driven scientific exploration. By forming flexible consortia among government, academia, and industry, these hubs aim to foster innovation and workforce development in AI. The initiative aligns with national R&D priorities, emphasizing the critical role of AI in advancing scientific discovery and expanding infrastructure to support this mission across various disciplines.
Artificial Intelligence (AI)

National Foundation for the Centers for Disease Control and Prevention (363484)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $1,250,000
The National Foundation for the Centers for Disease Control and Prevention offers funding to support administrative expenses that bolster CDC's mission. This initiative enhances partnerships to address health threats both domestically and globally. Projects funded through this grant align with CDC's strategic goals, focusing on measurable outcomes such as program support and participation from various CDC Centers and Offices. Importantly, this grant only supports non-research activities.
Epidemiology & Public Health

Domestic Violence Prevention: Forensic Healthcare Services

US Dept. of Health & Human Services: Indian Health Service
Federal Government
United States
Unspecified amount
The Domestic Violence Prevention grant aims to enhance access to forensic healthcare services for American Indian and Alaska Native victims of domestic violence and related issues. By fostering multidisciplinary partnerships, this initiative promotes trauma-informed care and improves victim support across IHS Areas. The focus is on developing comprehensive, culturally sensitive services that ensure timely interventions and coordinated responses to vulnerable populations, thereby enhancing overall victim well-being and safety.
Domestic Violence Crime Victim Services Violence Prevention +1 more

Tribal Epidemiology Centers

US Dept. of Health & Human Services: Indian Health Service
Federal Government
United States
Unspecified amount
The Tribal Epidemiology Centers initiative aims to support currently unserved areas through a new cohort of TEC sites. Funded by the US Dept. of Health & Human Services: Indian Health Service, this program seeks to enhance public health capacity within tribal communities, ensuring access to essential health services and resources. The initiative underscores a commitment to addressing health disparities and promoting wellness among Native populations.
Epidemiology & Public Health Indigenous Health Systems Native American Services +1 more

Detroit Grants for Nonprofits Highlights

Looking for Detroit Grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Detroit Grants for nonprofits recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Detroit Grants for Nonprofits

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

100+ Detroit grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

32 Detroit grants for nonprofits over $25K in average grant size

16 Detroit grants for nonprofits over $50K in average grant size

19 Detroit grants for nonprofits supporting general operating expenses

85 Detroit grants for nonprofits supporting programs / projects

700+ Grants on Instrumentl focused on Equitable & Affordable Housing

2,000+ Grants on Instrumentl focused on Art & Culture

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Detroit grants for Nonprofits?

Most grants are due in the first quarter.

Q1
35.4%
Q2
20.9%
Q3
25.2%
Q4
18.6%

Typical Funding Amounts

What's the typical grant amount funded for Detroit Grants for Nonprofits?

Grants are most commonly $20,000.

$500 $500 Min.
$20,000 $20 K Median
$31,262 $31.3 K Average
$275,000 $275 K Max.

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