Best Grants for Capital Funding in Florida

The Basil O'Connor Starter Scholar Research Awards, offered by March of Dimes, support emerging researchers in maternal and child health. With a $150,000 grant over two years, the program prioritizes projects addressing preterm birth and health equity. Eligible applicants must be within four to nine years of completing their clinical training or terminal degree, holding a tenure-track position. This initiative aims to foster impactful research that enhances clinical treatments for serious maternal and newborn health conditions.

The William T. Grant Scholars Program provides crucial support for early-career researchers aiming to expand their expertise through innovative research and mentoring. This five-year program focuses on reducing inequality and improving the use of research evidence to benefit young people in the U.S. By emphasizing the development of new disciplines and methods, the program encourages applicants to take bold risks in their research trajectories, ultimately fostering a supportive academic community.

About Us

Making a Difference, Together

The Community Foundation of Monroe County (CFMC) builds a thriving, inclusive community through the power of philanthropy. By connecting generous donors with local causes, we help ensure Monroe County remains a place where everyone can thrive. Since our founding, we’ve been a trusted steward of community resources, fostering impactful collaborations and sustainable solutions to address challenges in education, health, poverty, and community development.

Skilled Trades Scholarship

The Greater Milan Area Community Fund is proud to support students pursuing skilled trades and hands-on career pathways that build practical skills, open doors to stable employment, and strengthen our local community.

Scholarship awards are typically paid directly to the accredited trade program or educational institution and are generally non-taxable.

Applications are evaluated two times each year for awarding in the six months after application and selection.

The Special Emphasis Limited Project Grant from the American Society of Colon and Rectal Surgeons aims to address health disparities in colorectal surgery. It focuses on improving care for racial/ethnic minorities, women, LGBTQ+ populations, and individuals with disabilities. Proposals should concentrate on patient-oriented interventions and may explore quality improvement, access to services, and enhancing workforce diversity. Funding of up to $20,000 is available for innovative projects that promote equity in colorectal healthcare.

The NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) support small businesses in conducting clinical trials for NIH-funded projects. This initiative encourages partnerships with investors to assist in the commercialization of innovations in neurological disorders. Applicants must submit a comprehensive Commercialization Plan detailing anticipated funding. The program aims to promote effective transitions from research to market, enhancing the development of drugs, devices, and therapies for neurological conditions.

The Spencer T. and Ann W. Olin Foundation Wetlands and Waterfowl Research Fellowship supports graduate students in North America conducting research on waterfowl or wetland biology. The fellowship, offering up to $9,500 annually, emphasizes applicant qualifications, research proposal soundness, originality, and potential contributions to conservation efforts. This competitive opportunity is renewable for up to two additional years for PhD students and once for Masters students, pending satisfactory progress reports.

Just One More Grant aims to transform lives by providing financial support to individuals and nonprofit organizations in the U.S. who are overcoming challenges like mental health issues, drug misuse, and educational barriers. The foundation encourages applications from those committed to personal growth and community support. Though current grants are paused for nonprofits, interested individuals with actionable plans are invited to apply. More information and past winners can be found on their website.

IMPACT 100 of Northwest Florida offers grants to nonprofit organizations in Okaloosa and Walton Counties, aiming to fund high-impact projects that transform lives. Grants start at $100,000, with specific focus areas including education, environment, family, health & recreation, and arts & culture. Eligible organizations must be tax-exempt and serve local communities. The grant process encourages collaboration among nonprofits, fostering innovative solutions for community needs.

The Michael R. Priddy Music Scholarship, offered by the Central Kentucky Community Foundation, aims to support graduating high school seniors from Hardin County Schools, specifically Elizabethtown and LaRue County High Schools. This scholarship is intended for students who have demonstrated involvement in classical orchestra or music performance, or who plan to pursue music studies, thereby fostering musical education in the community.

The United Way of St. Lucie & Okeechobee offers Community Impact Grants aimed at enhancing health, education, and financial stability in the community. Nonprofits serving these counties are encouraged to apply, provided they meet specific eligibility criteria, including being a 501(c)(3) organization and having operational experience of at least two years. This initiative focuses on addressing critical needs such as food security and housing assistance, fostering a sustainable and impactful community.

The Quality of Life Grants Program, established by the Dana Reeve Foundation, aims to enhance the lives of individuals with disabilities and their families by funding nonprofit organizations. Priority Impact Grants - Tier 2 provide support for critical issues affecting those with paralysis, with grants ranging from $25,000 to $30,000. These grants focus on improving access, independence, and community engagement through innovative programs, including assistive technology, disaster preparedness, and respite services.

The NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01) aims to support clinical trials that evaluate interventions for communication disorders. This funding opportunity encourages collaboration between NIDCD Project Scientists and investigators, focusing on trials that require FDA oversight, establish efficacy, or pose risks of harm. By fostering well-designed studies, the NIDCD seeks to advance treatment and prevention strategies in the field of communication disorders.

The NIDDK High Risk Multi-Center Clinical Study Cooperative Agreement (U01 Clinical Trial Required) invites applications for high-risk clinical trials that involve multiple centers and aim to change clinical practice or public health. Applicants are encouraged to submit Letters of Intent 30 days before the proposal deadline, with various deadlines set from February 2025 to October 2026. Planning activities must be completed before submission, and consultation with NIDDK staff is advised.

The John's Island Foundation (JIF) offers Core Grants annually to support capital needs of nonprofit agencies in Indian River County. Eligible agencies must be tax-exempt 501(c)(3) organizations that demonstrate a commitment to serving individuals facing challenges related to food, shelter, health, and education. JIF focuses on tangible capital improvements, ensuring that funds are used to enhance community services. This initiative reflects JIF's dedication to fostering a sustainable impact for those in need within the local community.

The Elizabeth M. Pfriem Foundation, established in 2015 in Rye Brook, New York, is committed to enhancing the human condition through grants to 501(c)(3) public charities. Focusing primarily on the greater Bridgeport, Connecticut area, it supports initiatives in education, healthcare, food security, and housing. The foundation prioritizes organizations demonstrating fiscal responsibility and innovative programs with significant impact potential, ensuring sustainable support for vulnerable populations, especially children and families in need.

The National Institutes of Health (NIH) is inviting applications for the Multidisciplinary Research to Accelerate Hepatitis B Cure in Persons Living with HIV and HBV (MRA-HBV) program. This initiative aims to enhance understanding of hepatitis B persistence and pathogenesis, identify biomarkers, validate drug targets, and create non-invasive diagnostics. It supports observational cohorts paired with multidisciplinary teams utilizing existing clinical data, contributing to innovative research in hepatitis B cure strategies.

The McMillen Foundation Grants Program supports research in cardiology, lipids, and organ transplant, along with educational initiatives and social services in Washington and Alaska. With a single grant cycle annually, nonprofits certified under 501(c)(3) can apply for funding, preferably those benefiting children and promoting equity. The foundation emphasizes programs that leverage the arts to foster social change, impacting youth and disadvantaged communities. Applications must be submitted by July 31 to be considered for the current cycle.

The Sensata Foundation, established in 2017, is a 501(c)(3) nonprofit supporting community development and STEM education across the U.S. With a focus on improving access to STEM resources and empowering youth, the Foundation partners with nonprofits to address food insecurity, homelessness, and environmental sustainability. By fostering community partnerships and providing financial support, Sensata Foundation aims to inspire future leaders and enhance the quality of life for all, particularly in underserved areas.

The AWWA Scholarship Program, administered by the American Water Works Association, offers a $5,000 scholarship to graduate-level students pursuing careers in the water industry. Recognizing the vital role of future professionals, AWWA aims to support education in water supply and wastewater management through this scholarship initiative. Founded in 1886, American Water is the largest U.S. investor-owned water utility, emphasizing the importance of investing in education for sustainable water solutions.

The Sonnentag Foundation Grant supports organizations in cities where County Materials Corporation operates, focusing on four key areas: Hunger & Homelessness Support, Service Members & Veterans Support, Sexual Abuse & Domestic Assault Services, and Mentoring & Skills Building. Eligible applicants must be 501(c)(3) recognized organizations that serve the broader community. The foundation aims to empower vulnerable populations, including veterans, to lead fulfilling lives and provide essential services for healing and personal development.

Our Mission

To advance Mayo Clinic’s commitment to be a socially responsible Enterprise by supporting and extending Mayo’s strategic mission of integrated practice, research and education through active community engagement practices.

Our Vision

To be a proactive partner, inclusive of diverse and underserved populations, and contribute to the overall health, sustainability, livability and vibrancy of the many communities we serve. Stakeholders will better understand and appreciate Mayo Clinic’s community engagement practices and our ongoing role in strengthening partnerships and creating positive social impact.

Community Contributions Program in Florida

Mayo Clinic in Florida is a not-for-profit organization with the primary mission of patient care. As a private trust for the public good, Mayo Clinic is dedicated to giving back to its local communities through its Office of Community Relations.

Mayo Clinic partners with others to ensure that:

• Our community investments align with our mission to advance patient care, research and education
• Our community is a welcoming, vibrant and healthy environment
• Our community is an environment that attracts and sustains a diverse Mayo Clinic workforce to provide the best patient care

Program Information

Mayo Clinic considers sponsorship and grant requests from registered 501(c)(3) organizations in northeast Florida for new/ongoing programs or other community outreach activities that support the stated goals. These may include:

• Health and Human Services
• Education and workforce development
• Belonging
• Youth enrichment
• Community events

Each request will be considered for alignment with any of the following health priorities:

• Access to Care
• Mental Health
• Food Environment - access to nutritious food

Access to Care

Mayo Clinic will offer one grant funding opportunity for the Community Health Needs Assessment priority area: Mental Health

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

HIV, AIDS, and prevention

Help with healthcare costs for HIV, AIDS, and prevention

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

HIV, also known as human immunodeficiency virus or acquired immunodeficiency syndrome, is a virus that attacks the immune system. When left untreated, it can develop into AIDS. HIV is a chronic disease that affects the immune system.

The 2026 Vilcek Prizes for Creative Promise in Biomedical Science will award three $50,000 prizes to exceptional young immigrant scientists in the U.S. This prestigious prize recognizes innovative research contributions in biomedical science. Eligible candidates must be under 38 years old, hold a doctoral degree, and have made significant achievements in their field. The Vilcek Foundation aims to highlight the impact of immigrant scientists on the advancement of biomedical research, fostering diversity and excellence.

The Lynde and Harry Bradley Foundation Grant supports organizations dedicated to preserving American exceptionalism through a commitment to individual liberty, free markets, and civic responsibility. It prioritizes proposals from 501(c)(3) organizations that promote informed citizenship and strong communities. With ongoing acceptance of Letters of Inquiry, the Foundation seeks to empower initiatives that align with its principles of limited government and the rule of law, fostering a rich community culture.

About Us

Our team is working tirelessly to heal the planet and ensure that a just and livable future prevails.

With three decades of clean energy industry experience, our leadership team draws upon a long track record of environmental stewardship and meaningful throughput to confidently navigate today's unprecedented challenges.

We are teaming up with local philanthropists, nonprofit organizations, advocates and elected officials to implement effective solutions towards stopping the climate crisis.

Solar Moonshot Program Grant

The Solar Moonshot Program is helping nonprofit organizations across the United States afford the switch to clean energy.

Grants up to $25,000 are typically awarded, with grant amounts dependent on various factors, including the organization’s need for funding. 

In addition to grants given through the program, we also offer short-term, low-interest recoverable grants to help cover the project costs offset by the Investment Tax Credit.

Grants for 2026 are made possible by the BQuest Foundation and two anonymous donors, and the program is managed by Hammond Climate Solutions Foundation. Learn more about the program's status and participants below! 

The NIDDK Disease Research and Translational Core Centers (P30 Clinical Trial Optional) program invites applications to support innovative biomedical research focused on cystic fibrosis, diabetes, and other chronic diseases. These centers foster collaboration, provide essential resources, and mentor early-stage investigators, enhancing the research landscape. Funding will support pilot programs and access to shared services, ensuring efficient use of resources while promoting a robust scientific community dedicated to advancing health outcomes.

The Charlotte CF Education Fund Grant aims to enrich the lives of school-age children in Charlotte County, Florida, by providing additional educational opportunities and workforce development. Funded by the Charlotte Community Foundation, this grant supports programs like afterschool initiatives, career development, reading programs, and feeding programs. Eligible applicants must demonstrate fiscal responsibility and primary service to Charlotte County residents, ensuring that grant funds effectively benefit the community.