Best Large Grants for Nonprofit Organizations in Florida

The heart of The NRA Foundation’s mission is preserving the core of our American values and traditions in our steadfast effort to Teach Freedom.

The NRA Foundation Supports Freedom, Family, and the Future of the Shooting Sports

Established in 1990, The NRA Foundation, Inc. (“NRA Foundation”) is a 501(c)(3) tax-exempt organization that raises tax-deductible contributions in support of a wide range of firearm-related public interest activities of the National Rifle Association of America and other organizations that defend and foster the Second Amendment rights of all law-abiding Americans.

The heart of The NRA Foundation’s mission is preserving the core of our American values and traditions in our steadfast effort to Teach Freedom.

Established in 1990, The NRA Foundation, Inc. (“NRA Foundation”) is a 501(c)(3) tax-exempt organization that raises tax-deductible contributions in support of a wide range of firearm-related public interest activities of the National Rifle Association of America and other organizations that defend and foster the Second Amendment rights of all law-abiding Americans. These activities are designed to promote firearms and hunting safety, to enhance marksmanship skills of those participating in the shooting sports, and to educate the general public about firearms in their historic, technological and artistic context. Funds granted by The NRA Foundation benefit a variety of constituencies throughout the United States including children, youth, women, individuals with physical disabilities, gun collectors, law enforcement officers, hunters and competitive shooters.

Women's Wildlife Management Conservation Scholarship

The Women’s Wildlife Conservation Scholarship, established by the NRA Women’s Policies Committee, is a renewable one-year $5,000 scholarship available to full-time college sophomores, juniors, or seniors. Thank you for your interest in the field of wildlife management, forestry, parks, or fish and wildlife conservation.

Scholarship Value

$2,500 per semester for up to two semesters. Recipients must maintain qualifications listed above to receive second installment.

The Mathers Charitable Foundation Grant focuses on advancing basic scientific research with the potential to transform human health. It supports institutions and investigators in fields such as immunology, cancer biology, and neuroscience while prioritizing impactful, foundational discoveries. The foundation empowers researchers to drive innovative solutions and foster meaningful contributions to science and society. Eligibility includes U.S.-based institutions and principal investigators with equipped labs, while ineligible entities include overseas institutions and private foundations.

The Junior League of Miami Community Grants aim to empower women, children, and families in Miami by addressing food insecurity and other critical issues such as homelessness and health. Organizations eligible for these grants must hold a 501(c)(3) status and serve Miami-Dade County. The league focuses exclusively on educational and charitable purposes, fostering women's leadership through community impact. Funds cannot be used for capital costs, operational expenses, or scholarships.

Cattaraugus County Trappers Memorial Scholarship

Created by the Cattaraugus County Trappers Association, this scholarship will be awarded to a graduating high school student who plans to pursue a degree in Natural Resources Conservation, Fish & Wildlife Management, Forest Management or similar area of study at a 2- or 4-year college. Financial need will be considered. Applicants must include list of outdoors sports in which they participate, a statement on importance of the role of sportsmen in conservation and management of fish and wildlife and natural resources, and information on career path in their goal statement.

The PRO 2026-06 Mental Health Wellness Uniting Grant aims to promote mental health wellness for families and youth in Hillsborough County. Approved by the Children's Board of Hillsborough County, this grant focuses on funding services that enhance behavioral support, resource navigation, and social connections. It targets parents of children aged 0-18 and youth aged 11-18, emphasizing collaboration and measurable outcomes. Organizations with expertise in mental health are encouraged to apply.

The Hanger Foundation's Empowerment Grants aim to positively impact individuals with physical challenges by supporting 501(c)(3) organizations in the U.S. The foundation focuses on rehabilitation services, athletic programs, and social activities that empower those with limb loss or differences. Grants are available for one year and prioritize projects that engage communities and enhance the quality of life for those in need. Organizations are encouraged to apply for funding that directly supports these goals.

The Tribal Colleges Research Grants Program (TCRGP) aims to enhance research capacity at Tribal colleges, focusing on agriculture, natural resources, and human sciences. By fostering leadership skills and knowledge, the program prepares students for competitive careers in agriculture and related fields. Projects involving innovative agricultural technologies, such as AI and data science, are encouraged. TCRGP also emphasizes training opportunities for undergraduate students to equip them for success in a digital society and explore pathways in AI for food and agricultural sciences.

The Patient-Centered Outcomes Research Institute (PCORI) intends to release an Implementation of Findings From PCORI's Research Investments PCORI Funding Announcement (PFA) on Aug. 4, 2026, seeking to fund implementation projects that promote the uptake of peer-reviewed findings from specific PCORI-funded patient-centered comparative clinical effectiveness research (CER) in the context of the body of related evidence. This PFA is an open competition opportunity for principal investigators to propose implementation projects that move evidence toward practical use in improving health care and health outcomes. Applicants may propose projects with budgets up to $1.8 million in total direct costs.

PCORI seeks to fund implementation projects that incorporate active, multicomponent strategies that will lead to uptake and integration of evidence generated by PCORI-funded research in practice settings. Implementation should target specific end users with a clear interest in — and ability to benefit from — the evidence. Proposed implementation projects will adapt findings as needed to facilitate uptake in the proposed settings and accomplish scale-up to reach larger numbers and/or scale-out to reach broader populations and settings. Applicants must demonstrate commitment and buy-in — including from leadership as well as frontline staff critical to the success of the project — from proposed implementation sites across multiple health systems, such that they provide a supportive context and infrastructure for undertaking the proposed project. In addition, projects should involve regional and national stakeholder organizations positioned to extend uptake in broader venues.  

Applications must be guided by an established conceptual model or framework and, where possible, by evidence regarding effective strategies for implementing evidence-based practices and interventions. Additionally, applications must include a rigorous evaluation plan that documents the successful execution of the implementation approach and the impact of the project on health care and health outcomes as feasible and appropriate within the project scope.

The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.

The Tobacco, Alcohol, and Cannabis Policy Research for Health Equity (R21 Clinical Trial Optional) aims to fund projects that explore policies related to tobacco, alcohol, and cannabis in the U.S. The focus is on understanding how these policies affect usage and exposure among disadvantaged populations. Engaging community organizations is essential for promoting equity in cancer prevention. This initiative is crucial for advancing health equity and reducing disparities in substance use.

The Tobacco, Alcohol, and Cannabis Policy Research for Health Equity grant aims to support research on policies affecting tobacco, alcohol, and cannabis use in the U.S. This initiative focuses on how these policies impact populations facing health disparities. Key components include engaging community organizations to advance equity in cancer prevention. Important deadlines for applications range from February 2025 to October 2027, providing opportunities for both standard and renewal submissions.

The Crawford Taylor Foundation focuses on enhancing programs that create lasting legacies in St. Louis. With priorities in community development, women's health, animal welfare, and environmental preservation, the foundation seeks to support 501(c)(3) organizations that meet specific eligibility criteria. They avoid funding multi-year grants or for-profit initiatives, emphasizing support for local causes and relief efforts deemed important by the Taylor family.

The Love IV Lawrence Foundation Grant focuses on suicide prevention and reducing stigma around suicidal ideation. It offers funding for projects in the Tampa Bay area that align with its mission. Eligible organizations must have a 501(c)(3) designation, make an impact in specified counties, and file a 990 form annually. This grant aims to support innovative approaches to mental health challenges and promote compassionate care among providers.

Arnold Ventures is dedicated to enhancing lives in America through evidence-based policies that address social injustices. Their Evidence and Evaluation team seeks to discover and evaluate solutions for pressing social issues by funding rigorous causal research. This initiative focuses on studies that employ quasi-experimental methods to assess the impact of programs and policies in key areas like education and public finance, ultimately guiding effective resource allocation and policy reform.

The CDC's K01 Mentored Research Scientist Development Award aims to support new investigators in conducting vital research to prevent interpersonal violence and suicide among children and adolescents. This grant encourages proposals that address critical public health issues, including adverse childhood experiences and youth violence, while fostering research independence. Applicants are expected to explore the impact of technology on violence and demonstrate the relevance of their findings to prevention efforts.

The REPI Challenge, initiated by the DOD's REPI Program, aims to protect critical testing and training capabilities through funded projects. Since 2012, over $193 million has been allocated to 69 initiatives, leveraging more than $512 million in partner contributions. The upcoming 2026 REPI Challenge will focus on strategic mission safeguarding, with up to $20 million available for preventing land use conflicts and enhancing military resilience, thus ensuring the longevity of vital defense capabilities.

The CREST program by the NSF aims to bolster research capabilities at minority-serving institutions (MSIs) through education and research integration. It specifically supports STEM doctoral programs and encourages proposals in high-priority areas such as AI and climate change. By enhancing the institutional capacity, the program seeks to increase the number of underrepresented doctoral graduates in STEM fields, thereby fostering diversity and innovation in scientific research.

BMO Gives is committed to fostering positive societal impact through community support and charitable initiatives. It focuses on enhancing community and economic resilience, as well as environmental sustainability. Eligible applicants must be registered charities or non-profits operating in Canada or the U.S. and align with BMO's corporate values, which promote inclusivity and non-discrimination. The program aims to support projects that address significant societal needs and empower local communities.

The Stray Dog Institute Grants aim to transform food systems by providing funding and support to nonprofits focused on animal welfare, environmental advocacy, and food justice. With grant amounts typically ranging from $2,500 to $10,000, the Institute prioritizes pragmatic solutions that foster dignity, justice, and sustainability. By addressing systemic issues in food production, they promote a compassionate approach that respects both people and animals. This initiative seeks to create a sustainable future for all stakeholders in the food system.

The St. Johns Cultural Council offers the State of the Arts Grants, providing six $1,500 awards to support individual artists and arts organizations in St. Johns County. Applications open annually on September 1st, aiming to fund innovative projects in various artistic disciplines. Priority is given to proposals that engage underserved communities or enhance arts education. This competitive grant process encourages creative proposals while ensuring minimal application burden on applicants.

The National Forest Foundation’s Collaborative Capacity Program offers financial support to enhance collaboration among local communities and partners, focusing on improving wildfire resilience and forest health. Grants range from $10,001 to $75,000, with a 20% cash or in-kind match requirement. The program aims to foster long-term stewardship outcomes for National Forest System lands, ensuring benefits to both forests and local economies through collaborative efforts.

The Gladys Brooks Foundation supports innovative projects in libraries, education, hospitals, and clinics. Grants focus on resource endowments, capital construction, and equipment aimed at improving public access to information and educational resources. Eligible applicants must be 501(c)(3) organizations located in specific states and demonstrate that projects will be funded primarily by the grant. Applications for direct salary support or research projects are not accepted.

The CDC's National Centers of Excellence in Youth Violence Prevention (YVPCs) aim to expand the evidence base for preventing youth violence among individuals aged 10 to 24. This initiative supports rigorous evaluations of prevention approaches, community engagement, and training for early career researchers. By establishing partnerships and focusing on communities with above-average youth violence rates, the YVPCs seek to enhance collaborative efforts and effectively disseminate research findings to inform future prevention strategies.

The Community Foundation of Carroll County supports nearly 70 academic, sports, special circumstances, and 4-H scholarships. Search scholarships by name, or sort by application type.

Jay A. Graybeal Scholarship

The purpose of the Jay A. Graybeal Scholarship is to provide scholarships to college bound high school students, or students currently enrolled in undergraduate studies or pursuing post-graduate studies in general history or a specialty area of studies in history to include but not limited to; museum studies, archival management, library science, historic preservation, material culture, American Studies, archaeology, anthropology, art or architectural history or preservation technology; or to students pursuing a recognized certification or apprentice program dedicated to traditional arts, industries, trades or crafts.

The Scholarship amount is $1,000.

The Lauren Townsend Memorial Wildlife Fund, established in 1999 in memory of Lauren Townsend, supports 501(c)(3) nonprofits in the U.S. focused on animal welfare and wildlife preservation. Grants are awarded to organizations with specific project funding needs and budgets under $250,000. Smaller nonprofits are encouraged to apply, while general operating expenses and lobbying activities are not funded. The fund honors Lauren's passion for animals, continuing her legacy of support for those in need.

About

The American Society of Mammalogists (ASM) was established in 1919 for the purpose of promoting interest in the study of mammals.

ASM Mission Statement

The mission of the American Society of Mammalogists is to advance the scientific understanding of mammals globally, to diversify the profession of mammalogy, and to promote science as the basis for the conservation and management of mammals. The Society achieves these goals through publications, grants and fellowships, annual meetings, and other education and outreach activities.

Stephen Jenkins Scholarship in Mammalogy

One of Steve Jenkins’ most meaningful legacies is found in the hundreds of students he taught and mentored over his 37 years in the Biology Department at the University of Nevada, Reno. He taught a wide range of classes including introductory biology, ecology, mammalogy and research design, and served as graduate advisor to more than 30 students. His research focused on beavers, wolves, wild horses, and ground squirrels. Steve worked to pass on his own belief that critical thinking is not just a fundamental tenet of sound science, but a force for good. He wrote the book How Science Works, an effort to demystify the scientific process for nonspecialists. In his retirement he wrote a second book, Tools for Critical Thinking in Biology. Steve has been a member of American Society of Mammalogists (ASM) since 1974.

Scope and Rationale of the Award

The new Stephen Jenkins Scholarship Award would be available to a graduate student in a North American university whose research is focused on one or more mammalian species. This would include field research (and lab research that supports and augments field research) in such fields as animal behavior, ecology, evolution, and conservation biology. ASM supports research on all aspects of mammalian biology, and the award will provide support for early career mammalogists. 

Use of Funds:

The award may be used only for research expenses, in the field or in the laboratory, research related travel, laboratory supplies, equipment, and attendance at professional meetings.  The current award is for $5000.