Best Large Grants for Nonprofit Organizations in Florida

The Sustainable Forests and Communities Grant aims to foster environmentally and economically sustainable forest communities in the U.S., particularly where the Weyerhaeuser Family has interests. It prioritizes projects enhancing the environment, economy, and community through sustainable practices. Eligible organizations must be 501(c)(3) tax-exempt entities operating in forested areas, focusing on integrated approaches that value forest ecosystem services. This initiative encourages local job creation, sustainable economic activities, and innovative partnerships to achieve sustainability goals.

The AAAAI Travel Scholarship supports eligible professionals to attend the AAAAI Annual Meeting in Philadelphia from February 27 to March 2, 2026. This event features plenary sessions, workshops, and presentations on current research in allergy and immunology. The scholarship not only provides financial assistance but also fosters opportunities for networking and collaboration among attendees, enhancing their knowledge and experience in the field.

The Alpha Gamma Delta Foundation provides grants aimed at combating hunger in the U.S. and Canada, focusing on direct food assistance, food rescue, and nutrition education. Eligible organizations can receive up to $10,000 in funding, with an average grant size of $5,000. Since its inception, the Foundation has awarded over $2 million to support local food programs, ensuring communities have access to essential resources and assistance for those in need.

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

Breast Cancer Screening & Prevention Initiative

The Breast Cancer Screening & Prevention Initiative, supported by the McKesson Foundation and administered by the NAFC, aims to expand access to lifesaving breast cancer screening and prevention services for uninsured and medically underserved. Through this initiative, the NAFC will provide $30,000 grants to members to establish or strengthen breast cancer screening programs in alignment with evidence-based guidelines from the U.S. Preventive Services Task Force and the American Cancer Society. Funding will support activities such as improving patient identification and referral systems, increasing access to mammography services through partnerships or mobile units, strengthening staffing and technology capacity, and providing patient education and case management to ensure follow-through with recommended screenings. By enhancing early detection and preventive care, the initiative seeks to reduce barriers to care and improve health outcomes for women who might otherwise go without critical cancer screening services.

The Paul L. Busch Award, provided by the Water Research Foundation, honors individuals for innovative research in water quality. This prestigious award supports promising researchers with a $100,000 grant to advance their work. The selection process is inclusive, with no restrictions based on race, gender, or nationality, and encourages applications from diverse candidates. Recipients are expected to collaborate with U.S.-based organizations, fostering practical applications of their research in the water environment.

The W. Wesley Eckenfelder Graduate Research Award, administered by the AEESP Foundation, recognizes outstanding graduate students in environmental engineering and science whose research enhances wastewater management knowledge. This prestigious annual award offers a $1,500 honorarium and a plaque for winners, along with a $500 travel stipend for attending the AAEES awards ceremony. Eligible candidates include both Master’s and Ph.D. students who demonstrate exemplary academic performance and innovative research contributions.

The J.R. Simplot Company Foundation Grant supports U.S. non-profit organizations focused on art, education, youth, community, and global food and agriculture. Established in 1929, the foundation is committed to enhancing community welfare through creative cultural endeavors, educational initiatives, health services, and youth programs. Applications are reviewed quarterly, ensuring a timely response to organizations dedicated to making a positive impact in their communities.

AmeriCorps Seniors RSVP Opportunity

About RSVP

Established in 1971 and now one of the largest senior volunteer programs in the nation, AmeriCorps Seniors RSVP engages people ages 55 and older in a diverse range of volunteer activities. AmeriCorps Seniors RSVP volunteers tutor children, help prepare simple taxes, assist victims of natural disasters, provide nutrition/food support, facilitate opioid and substance abuse education workshops, and serve in their communities in many other ways. AmeriCorps Seniors RSVP volunteers choose how, where, and how often they want to serve, with commitments ranging from a few hours to a maximum of 40 hours per week. While serving, AmeriCorps Seniors RSVP volunteers improve their own lives by staying active and civically engaged. 

Funding Priorities

AmeriCorps Seniors RSVP programming is designed to meet community needs. Applicants may propose activities intended to address community needs by thoroughly explaining the unmet need and activities to be completed by volunteers to address that need. In addition, AmeriCorps is interested in programming that addresses agency priorities. AmeriCorps Seniors RSVP priorities for this funding opportunity are:

• Supporting Older Adults and Caregivers: Provide respite, support groups, system navigation, care coordination, and resources for older adults, including custodial grandparents, and caregivers.
• Helping Older Adults Re-enter the Workforce: Offer job readiness, mentoring, training, and remove barriers to employment for older adults (volunteers provide services, not seek jobs).
• Building Strong Families: Support parents in helping children succeed, mentor parents, connect families to resources, and strengthen community partnerships.
• Preventing and Mitigating Fraud and Scams: Use digital navigators and other strategies to protect older adults from financial fraud and exploitation, including emerging AI-driven scams.
• Reducing Homelessness: Develop or renovate affordable housing, assist people experiencing homelessness in finding and maintaining permanent housing, and address housing needs for vulnerable populations.
• Supporting Behavioral Health Initiatives: Improve mental health, reduce isolation, prevent substance use, provide harm reduction tools (Naloxone, fentanyl test strips), peer support, and recovery services.

Award Funding Requirements

Applicants must construct the budget in the following manner. The federal share of the budget must not exceed $75,000 plus up to $350 for every unduplicated volunteer, whether or not they serve in an outcome-based work plan. 

The Pierce's Disease and Glassy-winged Sharpshooter Board offers grants to support research and outreach aimed at safeguarding California vineyards from serious pests and diseases. Prior funding has varied from $4,300 to $383,000, with projects typically lasting one to three years. Emphasis is placed on solutions that effectively address pest issues, encouraging multi-disciplinary teams to enhance the impact of their work on winegrape health.

The Garden Club of America Board of Associates Centennial Pollinator Fellowship offers funding for research on pollinator decline, specifically targeting bees, bats, butterflies, and moths. This fellowship, established in 2013, supports graduate students in U.S. institutions with annual funding typically around $4,000. It aims to enhance knowledge in pollinator science while fostering a new generation of scientists dedicated to conservation. Recipients may reapply for additional funding in subsequent years.

The Down Syndrome – Aim High Scholarship, offered by The Community Foundation for the Greater Capital Region, empowers students pursuing careers in special education or therapy for individuals with Down Syndrome. This scholarship supports dedicated individuals committed to improving the lives of others through education and professional development. Since 1968, the foundation has focused on enhancing community well-being, making this scholarship a vital resource for aspiring professionals in the field.

The Carl and Marilynn Thoma Foundation offers Special Project Funding to support innovative initiatives in the arts, particularly in under-resourced areas. This grant encourages collaborative projects that enhance community engagement and education, focusing on art exhibitions and scholarships in the greater Texas Panhandle. By fostering leadership and creativity, the Foundation aims to empower individuals and organizations to make a lasting impact in the fields of art and art history.

The US Dept. of Health & Human Services, through the Eunice Kennedy Shriver National Institute of Child Health and Human Development, is set to announce a funding opportunity focused on HIV research for pediatric and maternal populations. This initiative aims to foster innovative clinical trials addressing critical research areas in HIV, inviting collaborations from experts in various fields. Applications are not currently solicited, but potential applicants are encouraged to prepare for this opportunity.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5433 - Optimizing Membrane Biofouling Control in Potable Water Reuse Treatment Trains

Grant Information

Main Objective: Evaluate alternative biofouling control chemicals and operational strategies to optimize performance across the potable reuse treatment train while maintaining treatment performance and finished-water quality. Supporting objectives include:

• Identify and assess alternative biofouling control chemicals and operational strategies that can reduce membrane fouling and differential pressure, reduce cleaning frequencies, minimize degradation of ultraviolet transmittance (UVT), and reduce lifecycle cost.
• Evaluate treatment-train performance impacts, including effects on membrane system performance, membrane lifespan, UVT, and ultraviolet advanced oxidation processes (UV-AOP) performance and energy demand, finished-water quality, and concentrate management.
• Quantify lifecycle benefits and tradeoffs associated with selected strategies, including energy and chemical consumption, membrane replacement and cleaning frequency, monitoring and reporting requirements, operator safety and chemical handling, environmental considerations, and capital/operating and maintenance costs.

The Longleaf Landscape Stewardship Fund Grant, managed by the National Fish and Wildlife Foundation (NFWF), provides funding for projects aimed at restoring and conserving longleaf pine and bottomland hardwood forests. With approximately $30 million available for 2024, grants range from $250,000 to $3,000,000. This initiative, supported by various federal and private entities, emphasizes the importance of ecological preservation and sustainable land management practices.

The H. Hovnanian Family Foundation Grant supports the Armenian community in Armenia and the U.S., focusing on Monmouth and Ocean Counties, New Jersey. The Foundation prioritizes education, healthcare, arts, and youth development through grants to registered non-profits. Proposals should demonstrate sustainability and community impact, with favorable consideration given to projects that engage local stakeholders and foster collaboration. Applications are accepted year-round, with a maximum funding limit of $10,000 for operational expenses.

The Dr. Bruce D. J. Batt Fellowship in Waterfowl Conservation honors the legacy of Dr. Bruce Batt, a leading figure in waterfowl research. This fellowship offers up to $5,000 annually to graduate students at North American universities conducting vital research on waterfowl and wetlands. Renewable for up to two additional years for PhD students, the fellowship promotes the integration of sound science in conservation efforts, supporting the next generation of waterfowl professionals.

The NIHCM Journalism Grants support projects that enhance health reporting and education, targeting critical issues such as healthcare affordability, pharmaceutical pricing, provider market dynamics, and chronic disease management. This initiative emphasizes the importance of informing policymakers and the public on how to improve healthcare quality and access in the U.S. Proposals may also explore the role of artificial intelligence in healthcare delivery. Applications are welcome from journalists, nonprofits, and universities.

Morris Animal Foundation invites Established Investigators to submit pre-proposals for research focused on reptile and amphibian health. This initiative emphasizes the importance of animal health and welfare while facilitating impactful conservation efforts. Proposals must demonstrate clear animal health needs, collaborative strategies, and potential benefits to wildlife populations. Funding for these projects is anticipated to average around $100,000 over a maximum duration of 36 months, fostering innovative solutions for pressing health challenges in these species.

The St. Mary's Bank Charitable Foundation 1908 Funds Grants provide financial support to nonprofit organizations in New Hampshire, focusing on community development and services. Established to uphold St. Mary’s Bank's commitment to social responsibility, these grants, ranging from $500 to $5,000, aim to foster financial independence and address issues like homelessness, youth support, and civic engagement. The Foundation prioritizes projects that benefit local communities and promote long-term sustainability.

The Zero Hunger | Zero Waste Foundation Grant supports nonprofit organizations focused on ending hunger and reducing food waste. Since its inception, the foundation has allocated over $59 million to enhance food security through innovative programs and community engagement. Eligible applicants include 501(c)(3) nonprofits addressing critical needs such as food access, nutrition education, and support for vulnerable populations. This initiative aims to create equitable food systems and ensure that no one goes hungry.

The Bay Area Lyme Foundation Grant supports innovative research aimed at improving diagnostics and treatments for Lyme disease. With a revised granting schedule, proposals can be submitted year-round, with reviews conducted three times annually. The foundation welcomes applications from universities, hospitals, and independent entities across the U.S., emphasizing the importance of addressing challenges in diagnosing and treating Lyme disease, especially for difficult cases.

The AAAAI Allied Health Recognition Award honors non-physician members who have significantly contributed to allergy and immunology education or research. As part of the American Academy of Allergy, Asthma & Immunology, this award emphasizes the importance of allied health professionals in advancing patient care. Eligible recipients include AAAAI Allied Health members who demonstrate excellence in their field, ensuring that contributions to the specialty are recognized and celebrated.

The Jeanette Zaichkin NRP Nursing Grant for Excellence and Innovation in NRP Education supports nurses dedicated to enhancing neonatal resuscitation training. This grant, offered by the American Academy of Pediatrics, provides up to $10,000 for innovative projects addressing key gaps in transitional physiology and evidence-based practices. Eligible applicants must be current NRP Instructors and work in neonatal care settings. The initiative aims to empower nurses in teaching essential skills for successful newborn resuscitation.

The AAAAI Distinguished Clinician Award honors individuals with a significant impact on allergy, asthma, and immunology. Recognizing those dedicated to patient care and clinical research, the award emphasizes excellence in diagnosing and treating allergic diseases. Recipients are selected based on their extensive clinical research and contributions to the field, including published works and presentations at national and international meetings. This prestigious recognition reflects the important role of clinicians in advancing allergy and immunology practices.

The HEAL Initiative aims to identify new druggable targets for pain within the understudied proteome. This funding opportunity invites applications for pilot projects that generate preliminary data and tools for exploring these targets. The initiative seeks to enhance research on understudied proteins related to pain management, providing essential funding for biochemical and biological work. This NOFO is part of the NIH's broader effort to develop novel medications that address various aspects of opioid addiction and its consequences.