Best Large Grants for Nonprofit Organizations in Florida

Program Description

Tau Grants are intended to strengthen the health and well-being of communities across our six-county region. These grants specifically support small nonprofit organizations that expand access to healthcare services or promote economic mobility. We are especially interested in organizations that both serve and are led by people from historically marginalized communities, including BIPOC (Black, Indigenous, and People of Color), LGBTQ+ individuals, people with disabilities, and immigrants. Tau Grants provide unrestricted general operating support to help these organizations thrive.

General operating grants strengthen the organization’s overall mission and goals and further its charitable purpose. The focus is not on specific projects or programs. Examples include strategic planning, technology upgrades, audits, and infrastructure costs such as utilities, rent, and personnel.

Focus Areas

Economic mobility is the ability of individuals to improve themselves and their families' economic condition.

Examples may include organizations focused on:

• job training/placement
• entrepreneurship
• social assistance
• financial literacy

The FY26 Bureau of Land Management Wildlife Resource Management Program aims to enhance wildlife resource management on public lands across the nation. With a focus on habitat protection, species reintroduction, and collaborative conservation efforts, the program addresses critical ecological needs while supporting the social and economic well-being of communities. Key initiatives include habitat treatments, monitoring efforts, and partnerships with state agencies to ensure effective management and recovery of priority wildlife species.

The American Heart Association is seeking proposals to study the prevalence and treatment of cardiovascular, kidney, and metabolic diseases among cancer patients and survivors. Given the over 16.7 million cancer survivors in the U.S., this research aims to highlight critical health disparities, identify treatment modalities, and explore shared risk factors. Applications focusing on underrepresented populations and utilizing real-world data sources are especially encouraged, aiming to improve health outcomes in this vulnerable group.

The Healthy American Forests Initiative, led by the National Fish and Wildlife Foundation (NFWF), aims to enhance forest health and resilience through targeted funding. This initiative anticipates awarding 10-15 grants ranging from $250,000 to $2 million, supporting projects up to 2 years in duration. A 20% non-federal match is required, and interested applicants are encouraged to collaborate with NFWF and Native Americans in Philanthropy for potential match funding.

The AWWA Scholarship Program, specifically the Woodard & Curran Scholarship, offers a $5,000 merit-based award annually to undergraduate or graduate students focused on water-related fields. This initiative aims to support historically marginalized communities, including women and BIPOC students, promoting equity in the water industry. With clean water being essential for community health, this scholarship reflects AWWA's commitment to nurturing the next generation of water professionals.

The NIAAA Integrative Neuroscience Initiative on Alcoholism (INIA) aims to renew support for two research consortia focusing on the biological mechanisms of excessive alcohol consumption and Alcohol Use Disorder (AUD). By utilizing advanced technologies and fostering collaboration across multiple sites, this initiative seeks to standardize neurofunctional measures and enhance reproducibility in findings. Investigators are encouraged to prepare for future applications to this NOFO, which will utilize the U24 activity code.

The Aerie Real Foundation™ Community Grant aims to enhance confidence, inclusion, and sustainability among young women while supporting non-profit organizations in the US and Canada. Grants of up to $10,000 are available to programs focused on mental well-being, fostering inclusive communities, and environmental protection. Applications are accepted from certified 501c3 nonprofits, with funding allocated for projects that align with the Foundation's mission. The goal is to empower the next generation and create a positive impact in local communities.

The Miami-Dade County Homeless Trust oversees the HOME Program Emergency Solutions Grant to address homelessness through a comprehensive Continuum of Care system. This program focuses on developing housing solutions for various priority sub-populations, including chronic homeless individuals and families. By leveraging funding for rental housing development, the initiative aims to provide sustainable housing and support services to eligible participants, ensuring that homelessness is rare, brief, and one-time.

The BJA FY 2026 Smart Reentry Demonstration Program aims to support state, local, and tribal governments in implementing effective reentry strategies for individuals transitioning from correctional facilities back to their communities. This program encourages comprehensive interventions designed to reduce recidivism by addressing various reentry needs, as outlined in the Second Chance Act. Applications are due by October 1, 2026, at 8:59 PM ET, and are submitted through JustGrants.

The Lazarus Family Scholarship in Bioethics and Humanities, offered by the AMA Foundation, supports students engaged in bioethics or the humanities, including art, music, and literature. This scholarship aims to foster the next generation of physician leaders by providing financial assistance to those who are committed to advancing health equity and community service. By recognizing diverse fields of study, it emphasizes the importance of interdisciplinary approaches in medicine and the humanities.

The U.S. Fish and Wildlife Service's Coastal Program offers vital technical and financial support for projects aimed at protecting and restoring fish and wildlife habitats in priority coastal ecosystems. Collaborating with conservation partners, the program ensures that all projects are scientifically sound and align with the missions of the Department of the Interior. Applicants must contact a local office for guidance before applying, ensuring projects meet strategic conservation goals.

Greater Toledo Community Foundation

Greater Toledo Community Foundation transforms generosity into lasting impact. With over $510 million in assets across 1,000+ funds, we've granted more than $370 million to strengthen education, health, arts, and social services throughout our region.

We connect donors with causes they care about while bringing together leaders, organizations, and resources to tackle our community's biggest challenges. What began with Walter E. Terhune's vision in the 1920s continues today as we help individuals, families, and businesses create positive change that will benefit our region for generations.

Ottawa County Community Foundation Grants

The Ottawa County Community Foundation, Inc. (OCCF) is a public charitable organization created by the citizens of Ottawa County to enrich the quality of life for individuals and families in Ottawa County. Grants from unrestricted funds support a variety of programs in the fields of education, health and social services, economic development, natural resources and the arts.

The Trout and Salmon Foundation Grant offers matching funds up to $5,000 to support projects aimed at restoring and enhancing trout and salmon habitats in North America. Established in 1969, the foundation prioritizes partnerships with local watershed organizations focused on habitat improvement. Grants are provided for projects that physically restore streams and fisheries, with on-site labor recognized in certain cases. The foundation seeks to diversify funding across various watersheds and regions, ensuring a broad impact in conservation efforts.

Our Mission

Our mission is to serve as the connection between our community and public education, evaluating needs and securing resources to enhance the quality of education.

Originally established in 1987 as the Dial-A-Teacher program in Lake County, Florida, by local business leaders in collaboration with the Lake County School District. The primary objective was to provide homework assistance to students, particularly those facing academic challenges. In 1988, the 501(c)(3) nonprofit organization was renamed the Education Foundation of Lake County, Inc. This rebranding marked a broader commitment to enhancing public education in the community. Today, the foundation continues to serve as a vital link between the community and public education, offering various programs and initiatives to support students and educators throughout Lake County. We are a member of the Consortium of Florida Education Foundations.

Teacher Grants

Each year, the Education Foundation funds projects that directly support students, teachers and classrooms in the Lake County School District. We’re especially excited to back initiatives focused on:

• Career & technical education
• Graduation and literacy improvement
• Financial education
• STEM programs
• Support for struggling students

Are you a teacher or support staff member with an innovative project idea that needs funding? The Education Foundation works with our community of supporters to help make that idea a reality. Through our easy-to-use online grant application, educators are encouraged to submit their proposed ideas to secure funding. 

For grants over $2,000, applicants need to get approval from their Principal and the Superintendent (or her designee). 

For Curriculum or Capital Expenses? Get approval by your Media Specialist and Principal.

The Jim and Margie Fegley Orchestral String Scholarship Fund, established in 2013 by Marjorie Fegley, honors her late husband, James E. Fegley. This fund supports Berks County residents pursuing music education, particularly in orchestral strings. Applicants must maintain a GPA of 3.0 or higher and have participated in music programs. The Berks County Community Foundation manages this fund, which contributes significantly to the local arts and education landscape, fostering musical talent in the community.

The Ornis Birding x Lost Birds Expedition Grant aims to inspire skilled young birders, aged 18-30, to explore remote regions and rediscover species that have evaded scientific detection for over a decade. Funded by Ornis Birding Expeditions, this grant offers up to $5,000 for innovative expeditions, encouraging participants to submit detailed observations and engage with local communities. The initiative seeks to fill critical gaps in ornithological knowledge while promoting conservation and ecotourism.

The Applied Drug Policy Research Experiences project aims to provide graduate students and recent post-graduates with hands-on research opportunities to support the National Drug Control Strategy. Through rigorous studies and data analyses, this initiative will explore the evolving dynamics of illicit drug supply and usage, assisting public health and safety officials in anticipating drug-related issues and crafting effective responses to safeguard the American public.

The Friends of Reservoirs: Large Grant supports fish habitat enhancement projects in manmade reservoirs, promoting conservation and partnerships. With approximately $250,000 in Federal funding and $500,000 from Bass Pro Shops, grants up to $75,000 are available. Projects must match funding and can be multi-year, with specific caps on subsequent funding. This initiative aims to address habitat impairments and enrich community quality of life through improved fishing opportunities.

The Friends of Reservoirs: Mossback Grant offers three grants of $1,000 in Mossback products to eligible members of Friends of Reservoirs organizations. Sponsored by Mossback Fish Habitat, these grants aim to enhance structural habitat in public waters. The total retail value is approximately $1,500. Applicants must cover freight costs, and a $25 application fee applies to each submission. This initiative supports habitat restoration efforts across member organizations.

The Senior Citizen Services Grants, established by Senior Citizens Services, Inc. at the Pinellas Community Foundation, aim to support wellness programs for residents aged 55 and older in Pinellas County. Eligible organizations can request funding for services such as mental health counseling, adult day care, and caregiver support. Emphasizing competitive funding, these grants prioritize projects that directly benefit the senior population, enhancing their quality of life through various wellness initiatives.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Miller Family Scholarship

This scholarship has been made possible by the generosity of Michael K. Miller, who established the Miller Family Scholarship Fund of the Community Foundation for Mason County. This scholarship is presented to instrumentalists graduating from Ludington High School.

The Limited Competition Small Grant Program for NIDDK K01/K08/K23/K25 recipients offers funding opportunities for pilot studies and feasibility research. This program aims to support researchers transitioning to independent investigator roles by providing resources for small projects that can yield preliminary data for future R01 applications. Key deadlines for applications range from February 2025 through January 2028, with specific dates for standard, renewal, and AIDS-related applications.

The See, Test & Treat Grant offers funding for a pathologist-led cancer screening program aimed at underserved communities. With a focus on health education, the program provides vital cervical and breast cancer screenings, ensuring same-day results and follow-up care. Eligible institutions can apply for funding up to $20,000 for single-year projects or up to $50,000 over three years. This initiative addresses health disparities, empowers communities, and enhances the visibility of pathology in healthcare.

Patagonia’s Corporate Grant supports grassroots organizations focused on bold, direct-action campaigns that address the root causes of environmental issues. The program emphasizes equity, inclusivity, and long-term change, targeting communities affected by environmental exploitation. Grants are awarded to innovative groups within the US and Canada, fostering civic engagement and measurable objectives. Patagonia prioritizes funding for initiatives that confront systemic bias and promote environmental justice, ensuring that diverse voices are represented in the environmental movement.

The ASTR Targeted Research Area Grant supports projects by scholars focusing on under-represented areas in theatre, dance, and performance studies. This includes research on Asian, African, Latin American, and Middle Eastern disciplines, as well as pre-1900 studies and essential translations. The grant, offering up to $3000, encourages recipients to publish their findings and collaborate with Theatre Survey editors. Eligibility extends to scholars with terminal degrees and graduate students, provided they are ASTR members.

The David Kelby Johnson Memorial Foundation offers grants to 501(c)(3) organizations focused on sight preservation, children's services, and environmental conservation, primarily in Utah. Established in memory of David Kelby Johnson, who tragically lost his life at a young age, the foundation aims to honor his legacy by supporting impactful charitable initiatives. Grants range from $5,000 to $100,000, with a commitment to improving communities both locally and globally.

The Ittleson Foundation, established in 1932, focuses on enhancing mental health, AIDS prevention, and environmental initiatives. It funds not-for-profit organizations aiming to improve public policy and the lives of citizens. The Foundation is particularly interested in innovative projects addressing mental health stigma, advancing preventative efforts, and supporting underserved populations. While it funds new initiatives, it does not typically support capital projects, endowments, or direct service programs outside New York City.