Best Large Grants for Nonprofit Organizations in Florida

The Blavatnik National Awards for Young Scientists honor exceptional faculty-rank scientists and engineers in the U.S. Recognizing achievements in Life Sciences, Physical Sciences & Engineering, and Chemical Sciences, each Laureate receives $250,000 in unrestricted funds. Nominations come from a select group of institutions and previous Laureates, emphasizing innovation and impact. The awards celebrate the future potential of young researchers, fostering diversity in STEM fields. The ceremony takes place annually in New York City.

The ASPCA National Shelter Grants Initiative offers up to $2.5 million in grants to support U.S. shelters and their communities. Grants ranging from $10,000 to $95,000 aim to enhance animal outcomes, psychological health, and access to veterinary care. Eligible applicants include non-profit organizations or municipal agencies with facilities for adoptable animals, while foster-based rescue organizations are excluded. This initiative is crucial in assisting shelters during challenging times.

The Capital Development (CAP) Grants Program offers financial support to non-profit cultural organizations for capital improvement projects in Miami-Dade County. This initiative aims to enhance cultural facilities, ensuring they are ADA accessible and serve the community effectively. Applicants must demonstrate readiness and secure matching funds. Priority is given to projects that improve accessibility and public service, ultimately enriching the cultural landscape for all residents.

The Braslau Family Travel Grant supports degree-seeking students and early career physicists in the US to attend APS March or April Meetings. Established in 2016, it honors the Braslau brothers, both distinguished scientists. Grants, ranging from $500 to $1,000, prioritize applicants lacking financial support, particularly underrepresented minorities and women. Funds are disbursed post-meeting, contingent on required documentation. This initiative fosters professional and academic interactions crucial for emerging physicists.

The John C. Lasko Foundation Trust Grant supports the construction of worship spaces across the nation, requiring churches to fund at least 50% of the project costs. Established by John C. Lasko, the foundation aims to build enduring churches that adhere to its mission. Grants are specifically for sanctuary construction, and applicants must own the land designated for the church. Notably, funds are not available for debt repayment or non-sanctuary areas.

The Community Foundation for Northeast Florida offers the Art Ventures grant for small to mid-sized arts organizations. This funding aims to enhance organizational capacity and support program development. Eligible applicants must hold 501(c)(3) status or partner with a fiscal sponsor, and demonstrate a commitment to arts and culture in Baker, Clay, Duval, Nassau, Putnam, or St. Johns counties. Additional support is available for Black-led organizations that meet specific criteria.

The Corporation Associates Seed Grant, offered by the American Chemical Society, provides up to $5,000 per year for innovative projects in chemical sciences education, public engagement in the chemical industry, and safety enhancements in chemistry. This grant supports one-time initiatives that align with the goals of the ACS Committee on Corporation Associates. Note that funding excludes research, equipment purchases, travel, and illegal activities, ensuring resources are allocated to impactful educational endeavors.

About

At Creative Pinellas, we believe the arts are essential to a vibrant, thriving community. Through programs, partnerships, and advocacy, we empower artists and cultural organizations across Pinellas County—enhancing quality of life, driving economic growth, and inspiring residents and visitors alike.

At Creative Pinellas, we’re all about celebrating the power of the arts to bring people together and make life better. We support local artists, spark creative experiences, and help build a cultural scene that makes Pinellas County an inspiring place to live, work, and play. From gallery shows and public art to festivals and performances, the arts play a big role in drawing visitors to the area—boosting local businesses and showcasing everything our vibrant community has to offer.

Arts Tourism Funding Program: Celebrating Pinellas County’s Creative Spirit Grant

Creative Pinellas is spearheading a transformative new arts tourism funding program designed to position Pinellas County as a premier cultural destination while strengthening its creative economy. On Tuesday, March 24, the Pinellas Board of County Commissioners approved the $500,000 program by unanimous vote. Creative Pinellas will direct the program, which is funded by Visit St. Pete-Clearwater (VSPC) with outreach and event support provided by St. Petersburg Arts Alliance and Clearwater Arts Alliance.

The inaugural program will fund a wide range of experiences created by artists and arts organizations selected through a competitive process. The experiences will shape a countywide, multi-week festival of the arts during Fall 2026 featuring performances, exhibitions, workshops, public art, and immersive cultural experiences across beaches, parks, downtown districts, and cultural venues. It is expected to reach an estimated 2.5 million visitors during that time.

This marks the first time Creative Pinellas has distributed arts funding to support not only individual artists and nonprofits, but also for-profit arts organizations.

Award Amounts and Frequency

• The panel plans to select approximately 20-30 arts experiences, totaling $350,000 to Individual Artists and Organizations. It is possible that more or fewer experiences will be selected. Another $50,000 is planned for those selected to provide opening and closing experiences for the month of the arts.
• The panel reviewing applications will be asked to fund in two categories: individuals and organizations.
• Individual Artists may apply for $5,000 to $15,000.
• Organizations may apply for $15,000 to $50,000.
• The panel predicts to select a very limited number of arts experiences at the higher funding levels.
• All applicants acknowledge that Creative Pinellas may offer funding at a different amount than applied for.

The Dr. John T. Macdonald Foundation Grant aims to enhance healthcare in Miami-Dade County through funding local community projects and medical scholarships. Established in 1992, the foundation has awarded over 597 grants, emphasizing direct medical care and health education for children and the economically disadvantaged. Eligible applicants include tax-exempt organizations with a focus on improving community health. The foundation's commitment to sustainable transformation inspires future generations to contribute positively to their communities.

The Indigo Oak Fund is a Colorado-based foundation dedicated to empowering individuals through support for education, the arts, and social justice. Focused on fostering lifelong learning and creative expression, the Fund aids various programs that enhance community engagement. It supports both youth and adult initiatives, including classes and community events in diverse artistic disciplines. By prioritizing equal opportunity and personal potential, the Fund strives to make a meaningful impact in the lives of individuals and the community.

The Garden Grant Program by Whole Kids Foundation offers $3,000 to schools and non-profits to create or enhance edible educational gardens. This initiative connects children with food, fostering curiosity and healthy eating habits. Eligible applicants include K-12 schools and organizations that regularly engage at least ten children in gardening activities. The program emphasizes the importance of hands-on learning about food and gardening, aiming to inspire a new generation of healthy eaters.

The Community Organizing Grants Program by the Peace Development Fund empowers local organizations to drive social justice initiatives. It supports groups that foster grassroots leadership and systemic change while dismantling oppression. Grants are primarily for general support, focusing on projects that align with their mission. Eligible organizations include those in the U.S., Haiti, and Mexico, while excluding completed projects or lobbying activities. This initiative encourages sustainable, community-based solutions and diverse alliances for a just society.

The NSF National Innovation Corps (I-Corps) Teams program aims to bridge the gap between scientific research and marketable technologies. By providing NSF-funded researchers with entrepreneurial education, mentoring, and funding, it accelerates the transformation of foundational discoveries into viable products and services. Participants engage in hands-on customer discovery and business model assessments, leading to improved product-market fit and strategic partnerships. This initiative fosters collaboration between academia and industry, enhancing the commercialization of deep technologies.

The Simons Foundation's Targeted Grants in Mathematics and Physical Sciences (MPS) program invites applications for funding to support research projects. Grants can be awarded for up to five years, with flexible funding levels. Eligible applicants include established educational institutions and research centers, and funding can cover various expenses such as salaries, travel, and equipment. Notably, the program does not allow funding for U.S. national labs. For complete guidelines, refer to the Simons Foundation's website.

The Local Section Member Engagement (LS-MEET) Grant Program, provided by the American Chemical Society, aims to enhance community engagement within local sections. With a funding cap of $2,000, this program supports initiatives that attract new members and strengthen existing communities. Eligible projects may include innovative technology use, targeted events for underrepresented local chemist groups, and activities that promote interaction among members. Applications should align with local section goals and detail specific budgetary needs.

The Boston Scientific Foundation Inc. offers charitable donations to U.S. Health Care Providers (HCPs) and National Associations supporting legitimate charitable efforts. These include funding for public health education, community health research, and charitable sponsorships. Eligible applicants are encouraged to reach out to the division Grant Coordinators for inquiries or submission guidance. This initiative aims to foster community well-being and enhance health outcomes through various charitable activities.

The Gilbert Memorial Fund Grant supports organizations conducting innovative medical research. Established in memory of the Gilbert family, this fund aims to promote advancements in various areas of medicine. Applications are accepted year-round, with a review meeting held annually on March 1. Grants typically range from $10,000 to $40,000, and eligible organizations must be recognized as 501(c)(3) entities. This initiative reflects a commitment to enhancing healthcare through research and development.

The AAO-HNSF Maureen Hannley Research Grant offers $50,000 for one year to support research addressing clinical gaps in otolaryngology. Eligible applicants include otolaryngologists in the U.S. or Canada, emphasizing projects with direct patient significance. The grant encourages junior faculty and mandates a letter of support from department chairs. Funds cannot cover principal investigator salaries but can support non-clerical staff. This initiative aims to enhance the development of independent researchers focused on patient-oriented outcomes.

The AHNS Pilot Grant offers $20,000 for one year to support innovative research in head and neck oncology. It is aimed at medical students, residents, and junior faculty who are AHNS members. The grant encourages clinical and translational studies that focus on the prevention, diagnosis, and treatment of neoplastic diseases in this field. Applicants must submit letters of support from their department and advisors to ensure adequate resources and supervision during the project.

The Peter G. Peterson Foundation Grant aims to address America's long-term fiscal challenges by promoting awareness and encouraging action. The Foundation supports innovative projects that align with its mission, particularly those by U.S.-based 501(c)(3) non-profits capable of national impact. Eligible applicants should have a minimum two-year existence and an annual budget of at least $1 million. The Foundation avoids funding organizations outside the U.S. or those involved in political activities.

The Major Research Grants on Reducing Inequality, funded by the William T Grant Foundation, support research aimed at reducing inequality in youth outcomes for ages 5-25 in the U.S. Grants range from $100,000 to $600,000 over 2-3 years. Studies can explore various systems such as education, mental health, and justice, focusing on mechanisms for change, intervention effectiveness, and improved measurement of inequality.

The ABC-CLIO Leadership Grant supports AASL Chapters in developing leadership programs for school library associations at various levels. This grant encourages initiatives that engage new members, train current leaders, and foster collaboration among organizations. Successful applications clearly define program objectives, participant groups, and include well-structured budgets and evaluation plans. The grant aims to promote innovative leadership approaches that can be replicated by other chapters, enhancing the overall effectiveness of school libraries.

The Gene Haas Foundation offers the Secondary Level Program Scholarship to promote education in CNC machining. This initiative aims to enhance manufacturing education and support local organizations improving community quality of life. The foundation has contributed over $225 million since 1999, focusing on scholarships and training programs for students. It also sponsors robotics and racing teams, ensuring hands-on experience for participants. Grants are awarded exclusively to tax-exempt entities, facilitating educational growth and community engagement.

The Oxbow Rescue Grant Program supports animal rescue organizations by providing financial assistance for various projects, including education, outreach, capital improvements, and operational support. With annual funding of approximately $25,000, grants are available to qualified groups that benefit small animals such as rabbits and guinea pigs. Oxbow aims to empower these organizations by offering resources and support to enhance their rescue efforts throughout the year.

Dwight Nicholson Medal for Outreach

This award recognizes the humanitarian aspect of physics and physicists created through public lectures and public media, teaching, research, or science related activities. Recognition consists of a stipend of $3,000, Nicholson medal, and a certificate which includes the citation for which the recipient has been recognized. Up to $1,500 will be available for the recipient's travel expenses to the meeting at which the Medal is presented. It will be presented annually.

The Stanley Smith Horticultural Trust Grant supports education and research in ornamental horticulture, funding projects that enhance public gardens, promote ornamental plants, and support related educational initiatives. Grants typically range up to $20,000, with a maximum of $25,000, focusing on project support rather than general operating expenses. Eligible organizations include 501(c)(3) public charities and similar entities worldwide, while the Trust does not fund individuals or capital campaigns.

The CFCC Program Grants, offered by the Collier Community Foundation, aim to support local nonprofits addressing community needs in Collier County, FL. Grants are available for arts, healthcare, education, and more, encouraging measurable impact. Eligible organizations must be tax-exempt and operational for at least two years. Applicants can request funding for new initiatives or program expansions to enhance their services. For more information, visit the FAQs on the foundation's website.