Best Large Grants for Nonprofit Organizations in Florida

About

The Children’s Brain Tumor Foundation (CBTF) was founded in 1988 by a group of dedicated parents, physicians, and friends to improve the treatment, quality of life, and the long term outlook for children with brain and spinal cord tumors through research, support, education, and advocacy to families and survivors. In addition to providing funds to research a cure, the organization is the nation’s leader in quality of life programs for families impacted by brain and spinal cord tumors. We support families from the day of diagnosis and throughout the brain tumor journey.

CBTF believes in the importance of being responsive to the needs of everyone in the brain tumor community regardless of their racial/ethnic background. We believe in the importance of a culture that values people of all racial/ ethnic backgrounds. We value the many identities that an individual brings to the community and honor and appreciate the intersections of these identities. Our practice values respect, integrity and honesty. We are committed to inclusiveness. 

The Rosalie Out of the Ordinary Scholarship

Thank you for applying for the Rosalie Out of the Ordinary Scholarship. This opportunity is given in memory of Rosalie Ou, a brain tumor survivor who brought positive energy and creativity everywhere she went. Her passions were fashion, art, and friendship. Rosalie taught many of us the art of origami and at the same time instilled in us lessons about how to live a life filled with joy. Rosalie was not able to complete her degree at the Fashion Institute of Technology. In her memory we dedicate this scholarship to a student who wants to fulfill their dream of a career in fashion or art.

The Elaine Ehlers Arts Scholarship, established in 2002, offers $5,000 to graduating high school seniors in New Jersey who demonstrate artistic excellence in various disciplines such as dance, drama, visual arts, or music. The scholarship is awarded based on a panel's evaluation of work samples and character. This initiative honors Elaine Ehlers' legacy, promoting arts education and supporting students pursuing their creative passions at accredited institutions.

The Peacock Foundation Inc. grants support the health and well-being of South Florida's children and families through contributions to eligible 501(c)(3) public charities. The foundation prioritizes proposals that address human services, education, health, youth, elderly care, disabilities, arts for educational purposes, and environmental education. All applicants must submit a letter of inquiry detailing their mission, project description, community served, and funding request. The foundation does not fund capital campaigns, individuals, or lobbying efforts.

The Larry H. & Gail Miller Family Foundation offers General Operating Grants aimed at 501(c)(3) nonprofits that serve the west side of Salt Lake City. Grants of up to $10,000, with an average of $5,000, support initiatives in health, shelter, education, economic self-reliance, and cultural enrichment. Applications are reviewed monthly. Organizations must be registered as nonprofits and align with the Foundation's focus areas to be eligible for funding.

The Rays Baseball Foundation Community Fund Grant supports local nonprofits in the Tampa Bay area, enhancing programs with over $1.8 million granted to more than 350 organizations. Eligible applicants must be 501(c)(3) entities operating in specific counties and submit an online application. This initiative aims to foster community development and support critical local services.

The United Way of St. Johns and Putnam Counties offers a Strategic Grant Fund aimed at empowering smaller nonprofit organizations that are often overlooked for traditional funding. Established in 1957, the organization focuses on critical areas such as housing stability, financial security, food access, and education. The goal is to support grassroots initiatives that create measurable impacts for residents, ensuring everyone has the opportunity to thrive in their communities.

The Penn National Gaming Foundation Grants support various community initiatives across North America, emphasizing education, health services, and cultural affairs. Launched post-Hurricane Katrina, the foundation aids local nonprofits, enhancing community development, public safety, and veteran support. The grants cater to organizations that address the needs of children, senior citizens, and disadvantaged populations, ensuring a broad impact in areas where Penn National Gaming operates. This commitment reflects the foundation's dedication to uplifting communities and fostering resilience.

The CDV5 Foundation Grant supports charitable organizations, churches, and government entities that meet IRS 501(c)(3) requirements. This grant aims to nurture successful children, foster stronger families, and cultivate healthier communities. Through partnerships, the foundation provides resources to help individuals reach their full potential. Applicants may submit one request annually for operating, capital, or program support, while event sponsorships are also considered. The foundation encourages applicants to consider their budget and history with the foundation when requesting funding.

The Walter Blackburn Scholarship, established by Alpha Blackburn in memory of her husband, supports Marion County residents pursuing degrees in design, architecture, fine arts, performing arts, or construction management. Eligible students must demonstrate financial need and maintain a GPA of 3.0 or higher. Preference is given to public school and minority students. Awards cover educational expenses at accredited institutions, including tuition, fees, and sometimes room and board, fostering educational opportunities in Central Indiana.

The Curtis Gates Lloyd Research Fellowship, provided by the Lloyd Library and Museum, supports research in various fields, including botany, conservation, and history of science. This fellowship offers a stipend of $2,000 for local applicants and $3,000 for those from outside the region. To be eligible, applicants must hold at least a Bachelor’s degree and commit to conducting research at the library for a minimum of 20 hours per week. The fellowship duration ranges from one to three months.

The FRS Community Grant Program supports rural communities served by NTCA members, offering grants up to $5,000 for various local initiatives. Priority is given to projects that promote economic development, education, health, and public service. Eligible applicants must secure a 10% match of the grant amount requested. Ineligible projects include overhead expenses, individuals, and those without secured funding. FRS aims to foster sustainable and engaged rural communities through these efforts.

Our Mission

Empower donors to fulfill their passions and dreams by establishing charitable vehicles designed to create a positive and enduring impact on Jewish Buffalo, Western New York and the World.

Golden Goldman Fund

The Golden Goldman Philanthropic Fund’s mission is to maximize local impact in support of: Women’s issues including reproduction and choice; Arts and Culture; Literacy; Reducing Income Inequality; and Judaism.

Funding will be awarded based on your proposal's potential impact. We will be looking at the applying organizations' fiscal viability and their ability to reach out to underserved individuals as part of our evaluation process. We do not usually provide funding for ongoing, existing programs.

The Jandy Ammons Foundation, established in 2012, is committed to enhancing local communities through innovative, project-driven initiatives. Focused on 'shovel ready' projects, it supports wildlife conservation, educational efforts, artistic installations, and Christian mission endeavors. By providing resources to IRS-recognized 501(c)(3) charities, the foundation aims to inspire community engagement and sustainable growth. The foundation reflects the collaborative spirit of its founders, Andy and Jan Ammons, who believe in hard work, integrity, and maximizing available resources.

The Graduate Education Fund: AUKUS Scholarships, established by the American Australian Association, supports American and Australian citizens pursuing full-time graduate studies in security, technology, and diplomacy. With up to $40,000 in funding for tuition and living expenses, this scholarship encourages innovative research in critical fields, particularly in relation to the AUKUS initiative. Applications are open biannually, fostering educational exchange and collaboration between the two nations.

The Mitsubishi Corporation Foundation for the Americas (MCFA) supports environmental initiatives across the Americas, focusing on biodiversity conservation, environmental education, justice, and sustainable development. They prioritize programs that align with these aims, particularly those involving 501(c)(3) organizations. MCFA seeks to empower marginalized communities, promote ecological stewardship, and encourage sustainable economic practices, ensuring that environmental burdens are shared equitably across all communities.

The Dementia CAReS Grants aim to enhance the lives of American Indian and Alaska Native communities affected by dementia. By providing funding, training, and support, this initiative focuses on developing actionable strategies within Tribal and Urban Indian settings. Key activities include establishing a network of dementia champions and promoting local best practices. The goal is to empower communities to improve dementia care and outcomes through collaborative efforts and innovative approaches.

The AWWA Scholarship Program, specifically the Veolia Water Technologies & Solutions Vernon D. Lucy III Scholarship, offers a $5000 award to undergraduate students pursuing careers in the water sector. Established by the American Water Works Association, this scholarship honors the mentorship of Vernon D. Lucy III and aims to support the next generation of water industry professionals. Eligible candidates must demonstrate interest in water-related fields, underscoring AWWA's commitment to fostering future leaders.

The PNC Foundation's Grow Up Great Grant is a significant initiative aimed at enhancing educational opportunities for children from birth to age 5. With a commitment of $500 million, this program focuses on improving school readiness through support in vocabulary development, social-emotional learning, and the arts. By partnering with community-based nonprofits, PNC aims to foster stronger, smarter, and healthier communities, ensuring a brighter future for the next generation.

The AWWA Scholarships Program, led by the American Water Works Association, aims to support the future of the water industry by investing in students. The Mueller Water Products Continuing Education Scholarship awards $5,000 to an undergraduate student employed by a water utility, emphasizing the importance of practical experience in education. This scholarship not only aids financial needs but also encourages students to pursue careers in water supply, fostering growth in this vital sector.

The Ag Health and Safety Grants, awarded by CHS and the CHS Foundation, aim to enhance agricultural safety and foster community well-being. These grants focus on educating youth and farmers about agricultural hazards, providing training for rural professionals, and developing essential safety guidelines. With a commitment to improving safety standards, the program has benefitted over 32,000 youth and supported more than 450 communities through safety initiatives and equipment, ensuring a safer future for all involved in agriculture.

The COPIC Medical Foundation Grants aim to improve healthcare outcomes by funding programs that enhance patient safety and reduce medical errors. With over $10 million awarded since its inception in 1991, the foundation focuses on scalable solutions to address healthcare fragmentation. This final grant cycle emphasizes innovative approaches that can be replicated across the healthcare community. Organizations must be 501(c)(3) certified or have a fiduciary partner to qualify for funding.

The BIE Professional Development Funding for STEM Educators and Students, offered by the Native Forward Scholars Fund, supports training opportunities in science, technology, engineering, and mathematics (STEM) for TCU faculty, staff, and students. This funding assists with costs related to professional development including continuing education, conferences, and certifications. Eligible applicants include educators at BIE-funded or controlled schools, as well as those at institutions with significant Native American populations, fostering increased representation and support for Native scholars.

The National Institute on Drug Abuse (NIDA) invites applications for longitudinal cohort studies focusing on HIV and substance use. This initiative aims to foster multidisciplinary research addressing HIV-associated co-morbidities and substance use disorders. The program encourages collaboration with a NIDA-funded Coordinating Center to enhance research agendas that align with NIH-HIV priorities, ensuring impactful policy and practice outcomes in the field of HIV/AIDS and substance use.

Farmer First Regenerative Pilot Program

Regenerative Agriculture is a conservation management approach that emphasizes natural resources through improved soil health, water management, and natural vitality for the productivity and prosperity of American agriculture and communities.

In December 2025, NRCS launched the NRCS Regenerative Pilot Program, a farmer first, outcomes-based approach to conservation designed to return the agency to its core mission – helping people help the land. NRCS is investing $700 million to specifically support regenerative agriculture, including:

• $400 million through the Environmental Quality Incentives Program (EQIP); and
• $300 million through the Conservation Stewardship Program (CSP)

This pilot program addresses whole-farm resource concerns through support for voluntary regenerative agriculture conservation plans. It also puts American farmers first as a part of the solution to Make American Healthy Again (MAHA) by supporting access to American-grown whole foods, critical to addressing the chronic disease crisis nationwide.

For too long, divided and highly specific funding pools have unintentionally encouraged isolated, practice-by-practice conservation, rather than holistic management. By integrating bundled regenerative practices into single applications, closing program loopholes, and recognizing outcomes, NRCS will deliver lasting benefits for farmers, natural resources, and the American consumer.

Emphasizing regenerative agriculture builds upon NRCS’s 90 years of existing conservation work by restoring land health, improving long-term productivity, and ensuring American grown production for the future. 

The contract length will be a minimum of 5 years.

The NASPGHAN Foundation Abbott Advanced Fellowship in Pediatric Nutrition offers up to $75,000 for one year of advanced training in pediatric nutrition for members of NASPGHAN. This fellowship aims to enhance pediatric nutrition expertise by supporting a well-defined clinical experience and focused research project. Eligible applicants must be MDs or DOs and members in good standing, with a preference for those seeking training at different institutions. This initiative addresses the increasing importance of pediatric nutrition in child health.

The Mobilize Power Fund Grant, offered by the Third Wave Fund, supports youth-led gender justice activism. This rapid response fund targets organizations led by young women of color and LGBTQ+ youth, providing up to $10,000 for urgent needs. It prioritizes groups addressing recent incidents that threaten their work, fostering community power and leadership. Organizations with budgets under $500,000 can apply, aiming for impactful, time-sensitive initiatives that promote social change.

The U.S. Department of Health & Human Services, through the NIH, invites applications for the U01 grant aimed at advancing gene-based therapies for ultra-rare neurological and neuromuscular disorders. This initiative focuses on IND-enabling studies and supports the development of innovative therapeutics with proven biological rationale. Applications must include robust data and compelling justification for the proposed clinical candidates, targeting a specific patient population to facilitate IND filing and subsequent clinical trials.