Best Large Grants for Nonprofit Organizations in Florida

The NIAID aims to support four Clinical Trials Networks (CTNs) by funding Statistical and Data Management Centers (SDMCs) to enhance HIV research. These SDMCs will oversee study designs, data collection, and compliance with regulatory standards while ensuring data quality and integration. This initiative is a crucial step toward ending the HIV epidemic, fostering innovative methods, and adhering to NIH data sharing policies. Applications for the SDMCs are now being solicited.

About Us

The American College of Obstetricians & Gynecologists (ACOG) is the leading professional membership organization for ob-gyns. ACOG champions ob-gyns in providing equitable, evidence-based care for patients today and into the future.

ACOG comprises more than 62,000 members across 12 Districts, representing regions in the United States, Canada, and Central and South America. These members maintain the highest professional standards and are united in their delivery of exceptional, respectful, science-backed care for patients. ACOG members include medical students, residents, practicing and retired physicians, and health professionals in related fields.

For nearly 75 years, ACOG has strengthened members with comprehensive, expert-reviewed practice guidelines; management tools; career development resources; and lifelong learning opportunities.

Pete and Weesie Hollis Community Service Award

The Pete and Weesie Hollis Community Service Award (formerly the President’s Community Service Award) was established by then President Richard “Pete” Hollis. The award was an outgrowth of Dr. Hollis’ presidential theme of caring for patients. Dr. Hollis felt strongly that many of the Fellows of ACOG gave hours of care and support within their community to underserved or poorly served patient populations, often with little or no remuneration or recognition.

The award is not to be given as a recognition of activities related to service to ACOG or activities that are based on support of the specialty in legislative or regulatory decisions. Recipients of the award will receive a $1,000 honorarium plus complimentary registration to the Annual Clinical and Scientific Meeting where the award is presented.

The Foundation for Sustainability and Innovation Grant aims to support projects that promote environmental restoration, preservation, and education, with a focus on sustainable resource use and community development. This grant encourages innovative approaches that connect urban and rural settings, enhance biodiversity, and foster creativity in addressing societal challenges. Eligible applicants include IRS-designated non-profits that align with the foundation's vision. The foundation also supports small presses and periodicals that creatively address sustainability issues.

The Rosenstiel Scholarship, part of the New Mexico Press Women Scholarship Fund, aims to support graduate students in journalism, communications, or law. Established in 2023, it encourages recipients to engage in investigative journalism and uphold First Amendment rights. Eligible candidates must maintain a minimum 3.0 GPA and submit relevant publications, letters of recommendation, and transcripts. This scholarship not only fosters academic excellence but also promotes ethical standards among future media professionals.

Levine Impact Lab

The Levine Impact Lab powers equitable transformation by investing in nonprofit leadership, building community organizations’ capacities, and building their capacity to accelerate positive social and environmental change.

We combine venture-capital expertise and inspired philanthropic thinking to radically amplify the value of giving.

Levine Impact Lab Operational Support Program

The Levine Impact Lab’s Operational Support Program is an 18-month, high-engagement operational partnership designed to help environmental organizations move strategic and financial priorities forward.

At the core of the program is hands-on operational support: our team works side-by-side with your leaders to drive progress on a critical project, whether it’s strengthening your financial infrastructure, increasing earned revenue, or planning for growth.

This is a working partnership. The grant funding and peer-learning community are designed to support and accelerate your momentum.

We are the best fit for organizations that:

• Operate at the intersection of environmental impact and social enterprise
• Are past the startup phase but still in a critical growth stage
• See LIL as a thought partner in unlocking strategy, scale, and sustainability
• Show up with clear goals and a commitment to moving the work forward

More information about participation commitments here.

What is Operational Support?

To get the most out of this program, organizations must come prepared with a specific project, workstream, or organizational challenge they want to tackle over the 18 months with operational support. 

Potential Area(s) of Support: 

• Financial strategy and planning
• Fundraising, development and donor engagement strategy
• Cost structure analysis
• Program development or expansion
• Corporate partnership strategy 
• New location or geographic expansion
• RFP support/capital planning
• Strategic planning
• Board engagement

Find examples of what past cohorts have worked on here.

People

The success of this program relies on having the right organizational leaders at the table. Each organization must commit two senior staff members who are equipped to make key decisions, drive implementation, and stay closely involved throughout the 18-month engagement. These leaders must:

• Have clear decision-making authority and/or strong backing from the Executive Director or CEO
• Be directly involved in the project or challenge the organization is addressing
• Be able to commit time, energy, and focus to move the work forward

There will also be opportunities to include additional staff members in operational projects, as needed, to ensure the right voices and expertise are present. 

Who this might include: Executive Director and Finance Director, Business Development Manager and Operations Lead, or Marketing Manager and Development Director, depending on the nature of your project.

What We Offer

• Tailored 1:1 operational support and strategic advising
• A national cohort of up to 10 organizations
• Peer network of strategic thought partners
• Virtual and in-person workshops and events
• Private Slack channel
• Exclusive alumni programming
• Grant funds over two years
• Supportive peer-learning community
• Accelerated organizational growth and momentum through strategic partnership with LIL

View Program Flyer here.

The Atlantic Salmon Federation Olin Fellowships support individuals aiming to enhance their knowledge and skills in salmon conservation and management. These fellowships are available annually for various pursuits, including research and graduate studies, without the requirement of being enrolled in a degree program. Eligible applicants must be legal residents of the U.S. or Canada, and the fellowships can be conducted at accredited institutions or active management programs.

The HEAL Initiative aims to address the complex interplay between chronic pain and opioid use disorder (OUD), affecting 40-60% of OUD patients. Through the IMPOWR initiative, this funding opportunity seeks to develop integrated care strategies that enhance treatment delivery at health systems levels. By identifying effective interventions and collaborative care models, the initiative strives to improve patient outcomes in managing both chronic pain and OUD, while emphasizing the roles of various healthcare professionals in this integrated approach.

The Young Forester Leadership Award, presented by the Society of American Foresters (SAF), recognizes exceptional leadership from young forestry professionals under 40 years old. This award highlights contributions to forestry through innovative projects and sustained leadership roles. Recipients receive a $500 honorarium, complimentary registration for the SAF national convention, and support for travel expenses up to $500. This prestigious accolade aims to encourage the next generation of forestry leaders to excel in their professional endeavors.

The National Institute of Allergy and Infectious Diseases (NIAID) is funding research to enhance drug susceptibility testing (DST) for mycobacteria. This initiative aims to improve testing for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, which are on the rise. Current methods are slow and ineffective against drug-resistant strains, making rapid DSTs essential for effective treatment and reducing transmission rates. Innovative approaches, including rapid genotypic and phenotypic methods, will be supported to address these challenges.

About

A History Of Making Waves

Carnival Foundation oversees the many philanthropic endeavors of Carnival Corporation as well as its employee-driven service group, the “Friends Uniting Neighbors” (F.U.N.) Team.

Carnival Foundation’s contributions are widespread, touching the communities where the brands visit and operate. From the cities where our brands are headquartered to ports we visit around the world, we endeavor to make a difference to the lives of many.

Through monetary and in-kind donations, innovative philanthropic programs, employee fundraisers and hands-on volunteer initiatives, Carnival Foundation and the brands of Carnival Corporation support a variety of organizations. Whether it’s providing meals to the homeless and abuse prevention or working toward medical advancement and educating youth, Carnival Foundation’s reach is communitywide.

Grants Or Sponsorships

To apply for a grant or sponsorship from Carnival Foundation, prospective applicants must complete an online application and include the following information and documents:

• A letter of request with a brief description of the organization, including its legal name, history, activities, purpose and governing board
• Purpose for which the grant is requested
• Grant amount requested
• Listing of other sources of financial support
• Operating budget of the project for which the funds are requested
• Organization’s annual budget
• Copy of the organization’s most recent audited financial statement
• Copy of organization’s most recent 990 filed with the Internal Revenue Service
• Copy of Internal Revenue Service determination letter indicating 501© (3) tax-exempt status as an organization that is not a private foundation
• Organization’s completed W-9 form
• Geographical area(s) served
• Organizations applying for a grant renewal must submit a final report detailing use of the prior grant award. Interim and final reports will be submitted through our online portal.

The Chipotle Cultivate Foundation Grant Program supports 501(c)3 non-profits dedicated to making real food accessible and fostering community growth. Established in 2011, this initiative aligns with Chipotle's mission to cultivate a better world. Eligible organizations can apply through an invitation-only process, focusing on those paving the way for a better future. The foundation also offers mentorship and resources to innovative ventures in the food industry.

The Trail Accelerator Grants aim to enhance mountain bike trail communities by providing essential planning and design services. With funding between $10,000 to $30,000, these grants support local organizations in creating sustainable trail systems. The initiative encourages projects that increase access and promote community engagement, particularly focusing on diversity and inclusion. Applicants must demonstrate the capacity to match funds, ensuring collaborative efforts to improve trail networks and experiences for all riders.

Catholic Extension's Enhancing Pastoral and Social Ministry Grants aim to empower the church to broaden its outreach and foster societal transformation through targeted pastoral and social initiatives. This program supports specific elements of the church's ministerial efforts, including funding for catechetical resources, marriage and family ministries, and social outreach for vulnerable populations. By investing in these areas, Catholic Extension seeks to enhance the church's role in communities, especially following disasters.

The National Institute of Mental Health is inviting research applications for the AIDS Research Center program, which includes Developmental Centers and full Research Centers. This initiative aims to enhance interdisciplinary HIV/AIDS research through collaboration and innovative approaches across various scientific domains. The program emphasizes alignment with national strategies and encourages applications from teams skilled in fostering partnerships with diverse stakeholders. Although applications are currently not being solicited, this notice allows potential applicants time to prepare strong proposals.

The Charles Hamlin Scholarship, established by Nurses Educational Funds, Inc., supports professional nurses pursuing master's or doctoral degrees in nursing. Applicants must hold a current RN license and demonstrate a commitment to nursing leadership, particularly in orthopedic care and the well-being of Native American communities. The scholarship honors Dr. Charles Hamlin's legacy, emphasizing the importance of cultural sensitivity in healthcare and preventing burnout among healthcare professionals. This award aims to empower future nursing leaders and enhance diversity in the field.

About

A History Of Making Waves

Carnival Foundation oversees the many philanthropic endeavors of Carnival Corporation as well as its employee-driven service group, the “Friends Uniting Neighbors” (F.U.N.) Team.

Carnival Foundation’s contributions are widespread, touching the communities where the brands visit and operate. From the cities where our brands are headquartered to ports we visit around the world, we endeavor to make a difference to the lives of many.

Through monetary and in-kind donations, innovative philanthropic programs, employee fundraisers and hands-on volunteer initiatives, Carnival Foundation and the brands of Carnival Corporation support a variety of organizations. Whether it’s providing meals to the homeless and abuse prevention or working toward medical advancement and educating youth, Carnival Foundation’s reach is communitywide.

In-Kind Donations

To apply for an in-kind donation from Carnival Foundation, submit an online application complete with the following information:

• A letter of request with a brief description of the organization including its legal name, history, activities, purpose and governing board
• Contact name and information, including phone number and address for the individual who is organizing the event
• Name and date of the event
• Average amount of funds raised from the auction in previous years and estimated number and demographics of the event audience
• Description of how funds raised from the donation will be used within the organization
• List of other cruise suppliers, if any, participating in the event
• An outline with details of Carnival’s publicity/promotional opportunities associated with the event
• Copy of Internal Revenue Service determination letter indicating 501© (3) tax-exempt status as an organization that is not a private foundation.
• Copy of organization’s most recent 990 filed with the Internal Revenue Service
• Geographical area(s) served

The 1954 Project - Luminary Award seeks visionary nonprofit leaders dedicated to advancing educational equity for Black students. Awardees receive $1 million in funding, leadership development, and networking opportunities. The selection prioritizes leaders demonstrating strategic vision, community commitment, adaptability, and collaborative spirit. Applicants must align with one of three impact areas: Innovation in Teaching and Learning, Diversity in Education, or Pathways to Economic Mobility, ensuring their initiatives foster systemic change and uplift marginalized communities.

The Resident Opportunity and Self-Sufficiency Service Coordinator (ROSS-SC) Program for Fiscal Year 2026 aims to empower residents of Public and Indian Housing by addressing barriers to economic self-sufficiency. Through grant funding from HUD, Service Coordinators assess individual needs, linking residents to educational, professional, and health resources. This support enables participants to achieve financial stability and independence, facilitating their journey towards self-sufficiency and enhancing their quality of life.

The Affordable Housing and Supportive Services Demonstration (AHSSD) aims to enhance housing stability and well-being for American citizens residing in affordable housing. By funding Community Action Agencies and tribes, the initiative fosters public welfare engagement and service enrollment. The program addresses diverse needs, offering referrals, case management, and direct services in education, childcare, mental health, and more, ultimately supporting economic mobility and reducing dependency among vulnerable populations.

The Thoroughbred Education and Research Foundation (TERF) offers grants to support education and research related to Thoroughbred horses. The foundation prioritizes funding for scholarships, educational programs, and equine research aimed at promoting thoroughbred health and welfare. Eligible applicants include qualified 501(c)(3) organizations, while those previously funded must submit reports before applying again. Notably, TERF does not provide funds for facilities caring for unwanted horses or cover overhead costs for grants.

The HIV Care Grant Program aims to enhance access to comprehensive, high-quality HIV care and treatment for low-income individuals in Pacific Island territories. Funded by the US HHS: Health Resources & Services Administration (HRSA), this initiative supports states and territories in developing effective systems of care, ensuring that those affected by HIV receive the necessary treatment and support to improve health outcomes.

The Thoroughbred Education and Research Foundation (TERF) offers grants to support thoroughbred health, welfare, and education. Focused on enhancing equine research and safety in racing, TERF prioritizes funding for scholarships, educational programs, and veterinary medicine. Eligible applicants must be recognized 501(c)(3) organizations, with a commitment to transparency in reporting. This initiative aims to significantly impact the thoroughbred industry by fostering improved care and understanding of these horses, contributing to their overall welfare.

The Curriculum and Instruction Honor Award, presented by SHAPE America, recognizes outstanding contributions to health and physical education curriculum research. This prestigious award highlights the importance of effective instructional practices that prepare students for active and healthy lives. Award recipients are selected based on their scholarship in health education and physical education, demonstrating commitment to excellence since the organization's founding in 1885. SHAPE America advocates for quality education and promotes the well-being of preK-12 students across the United States.

The Friends Foundation for the Aging Grant supports innovative and impactful programs aimed at addressing the needs of older adults, particularly within underserved populations. This Quaker foundation prioritizes collaboration and sustainability in its funding efforts. Eligible applicants must be 501(c)(3) public charities focused on enhancing the quality of life for aging individuals. Grants are typically awarded for one year and target organizations that align with the foundation's mission and values.

The Eastern Bird Banding Association is offering the Memorial Fund Research Grants to support research utilizing avian marking techniques, such as banding. Applicants must submit a detailed project proposal, including significance and budget, alongside their background in ornithology. Grants are open to all, particularly encouraging student applications, with no lifetime award limit per individual. Projects must focus on species within EBBA territory, ensuring marking techniques are integral to the research.

The SAF National Awards Program includes the John A. Beale Memorial Award, recognizing exceptional voluntary service in forestry by SAF members. Established to honor John Beale's legacy, this award is presented at the SAF national convention and includes a $500 honorarium, complimentary registration, and up to $500 for travel expenses. Nominees must demonstrate sustained commitment to the SAF and its mission, showcasing leadership and promotion of forestry principles.