Best Large Grants for Nonprofit Organizations in Florida

Gropper Clement Legacy Scholarship

To provide financial support to graduates of Huron, James Valley Christian, Kadoka and Miller High Schools.

The Environmental Engineering and Science Foundation offers six Master's Degree scholarships of $2,500 each for students pursuing advanced studies in Environmental Engineering or related fields. Eligible candidates must be U.S. citizens or permanent residents, have a strong academic record with a minimum GPA of 3.0, and be accepted into an accredited graduate program. This initiative aims to support future leaders in environmental engineering and science.

The Community Foundation of the Rappahannock River Region

The Community Foundation is a devoted advocate for the vitality and well-being of the Rappahannock River Region. We are a 501(c)(3) nonprofit that manages and distributes charitable giving in the counties of Stafford, Spotsylvania, King George, and Caroline, and the City of Fredericksburg.

Scholarships

One of The Community Foundation’s strategies for preserving and growing the quality of life in our region is supporting higher education for area students. Generous individuals and families, companies and organizations establish endowed scholarship funds and the proceeds from these funds benefit deserving students. Donors work with foundation staff to determine appropriate criteria for each fund. The Community Foundation currently administers more than fifty scholarship funds.

The Randy and Tina Harris Family Scholarship Fund

The Randy and Tina Harris Family Scholarship Fund is responsive to workforce readiness needs. This scholarship will be available on a rolling basis, students may apply at any time. Randy, a member of the Board of Governors at The Community Foundation starting in June 2022, owned two businesses in the area until 2021, Ultimate Subaru and Ultimate Buick GMC. As an active businessperson, philanthropist and retiree, he seeks to give back to the community he calls home. Tina and Randy have been friends to the foundation through leadership and participation, also contributing to the Virginia Education Improvement Scholarships Tax Credits and through the Randy and Tina Harris Family Charitable Fund. 

Apply for a Scholarship

While it is common for students to go to college after high school, earning a college degree isn’t the only option after high school, nor is it the right option for everyone.

The trades are vital, though often underappreciated, career fields that are essential for the functioning of society. Skilled trades are the backbone of our society and can be lucrative, stable career opportunities. In areas like construction, manufacturing, technology and medicine there are trades where people are able to make significant contributions to our world.

African Americans are very underrepresented in these fields. To ensure the brightest future possible, it’s crucial for African Americans interested in the trades to have the financial resources necessary to further their education.

Randy’s father, James Harris, had a successful career as a machinist and welder. He demonstrated that a college degree was not a necessity for a successful career. This scholarship was created for those African American students like James Harris, who are inspired to develop their talents in trades or taking non-traditional paths to further their education.

The ECMC Foundation focuses on eliminating equity gaps in postsecondary education by 2040 through strategic grantmaking and investments. They support organizations aiming to remove barriers to completion, build institutional capacity, and transform the postsecondary ecosystem. Eligible entities include nonprofit organizations, government entities, and postsecondary institutions. However, funding is not available for personal scholarships, political activities, or projects outside the U.S. that do not align with the Foundation's mission of diversity and inclusion.

The HEAL Initiative aims to address the significant overlap between chronic pain (CP) and opioid use disorder (OUD), with 40-75% of individuals affected by both. The IMPOWR project focuses on testing innovative interventions and implementation strategies to integrate care for CP and OUD across various health systems. The BEACON Center will enhance network coordination, build capacity, and develop resources to address barriers in service delivery, ultimately improving sustainability and scalability of evidence-based practices.

The DGF Bridge Grants provide essential financial support of $500 to professional dramatists facing hardships. This one-time award helps cover non-emergency daily expenses such as housing, utilities, and healthcare. Eligible applicants must be U.S.-based dramatists with limited financial resources and have not previously received a DGF Bridge Grant. By nurturing today's creators, DGF ensures the continuation of impactful storytelling in the theater community.

The Culpeper Rotary Foundation Scholarship supports residents of Culpeper County pursuing a four-year degree. With a $1,000 award renewable for four years, applicants must demonstrate financial need and maintain a GPA of 2.5 or higher. The Northern Piedmont Community Foundation manages the scholarship application process, emphasizing community involvement. This initiative reflects NPCF's commitment to enhancing educational opportunities in the region, ensuring that local students have the support they need to succeed in their academic pursuits.

The Howe Foundation, established by Thomas E. Howe in Clark County, Nevada, supports U.S. charitable organizations focused on education, medical advancements, and game hunters associations. Grants are administered by Wells Fargo Bank, with applications reviewed annually in September. Eligible organizations must be 501(c)(3) exempt under the Internal Revenue Code, ensuring support for meaningful community initiatives.

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

The Weitz Company Scholarship Fund

Can go to college or vocational school with a major or emphasis in one of the following fields of study:

• Architecture
• Civil Engineering
• Construction Management
• Interior Design
• Other Construction-related fields (e.g., construction project management, mechanical/electrical engineering and trades).

LSW Architects Legacy Scholarship

The LSW Architects Legacy Scholarship Fund was established in honor of LSW Architects' founding leaders and their ability to imagine and build in creative space. 

Number and Size of Awards:

The number and size of awards may vary and are determined by the selection committee. Minimum award amount is $2,500.

Number of Awards: 4

Total Amount Awarded: $10,000

Cures Within Reach

Cures Within Reach is the philanthropic leader in drug, device and nutraceutical repurposing research, which has the potential to transform the lives of patients with unsolved diseases by delivering treatments that can be used in the near-term. Our focus: we find and fund proof-of-concept clinical trials that, once successful, de-risk and catalyze follow-on funding, building the clinical evidence required for regulatory approval or to support off-label use by patients everywhere.

Clinical Repurposing Research to Impact US Veterans/Military

This Request for Proposals (RFP) from Cures Within Reach (CWR) is seeking clinical repurposing trials from US-based research institutions using already approved treatments to address unmet and high-priority medical needs of US veterans and/or active US military, such as mental health, post-traumatic stress disorder (PTSD) and brain injuries. Our strongest preference is for proof of concept, pivotal, Phase I or Phase IIA clinical repurposing trials. Eligible trials may be conducted at accredited US-based academic, nonprofit and governmental research institutions and/or health systems involved with medical research, including Veterans Administration (VA) health systems and hospitals. 

Repurposed therapies must be approved and/or generally recognized as safe for human use by some regulatory agency, such as the US Food and Drug Administration, European Medicines Agency, Health Canada or Japan’s Pharmaceuticals and Medical Devices Agency, and may include drugs, devices, nutraceuticals or diagnostics, as well as combination therapies. These repurposed therapies must be tested in a new indication for which they are not already approved or used widely in clinical practice as standard of care. Repurposed therapies also may be added to current standard of care to improve patient outcomes and/or quality of life.

The Parkinson Family Foundation Grant supports organizations focusing on Food & Water, Faith & Evangelism, and Health & Humanitarian Efforts. Applications are open year-round, with grants ranging from $1,000 to $5,000; larger requests are typically declined. Eligible applicants include schools, state governments, and 501(c)(3) nonprofits. The Foundation emphasizes selectivity and prioritizes organizations with established relationships and those promoting American ideals like freedom and justice.

The C.V. Glassco Memorial Scholarship Fund honors Mr. Clarence Verbal Glassco, a dedicated community volunteer and veteran. This scholarship supports full-time students pursuing higher education or approved workforce training in Alabama. Funded by the Community Foundation of Northeast Alabama, it covers tuition, housing, and books based on available assets. Applicants are encouraged to seek additional financial resources. This initiative preserves Mr. Glassco's legacy of service and commitment to education.

The Ralph W. Shrader Graduate Scholarship offers $3,000 to full-time graduate students in STEM-related fields at accredited U.S. institutions. Applicants must be U.S. citizens, enrolled in their second semester, and maintain a GPA of 3.5 or higher. The scholarship supports tuition and course-related expenses, encouraging students with financial needs to further their education. Notably, the expected graduation date cannot coincide with the award year, ensuring students are committed to their studies.

The Jennie K. Scaife Charitable Foundation Grant focuses on enhancing family support, women's and children's health, and animal welfare. It aims to fund programs that promote beneficial human-animal interactions and early intervention in addiction prevention. Eligible organizations must have a valid 501(c)(3) designation. Grants align with at least one of the foundation's focus areas, ensuring impactful contributions to community welfare and well-being.

About Levitt

The Levitt Family Foundation exists to strengthen the social fabric of America. We partner with communities to activate underused outdoor spaces, creating welcoming, inclusive destinations where the power of free, live music brings people together and invigorates community life.

Festival Grants

The Levitt Foundation is offering grants of up to $5,000 to U.S.-based 501(c)(3) nonprofits presenting free outdoor music festivals in 2026. 

The Rod's Tire and Service Scholarship Fund, managed by the Central Kansas Community Foundation, offers $2,500 to assist graduating Marion County high school seniors pursuing higher education or vocational training. The foundation, established in 1994, focuses on enhancing community welfare through charitable giving and emphasizes support for students majoring in agricultural fields. This scholarship aims to empower local youth and strengthen the community by investing in their educational futures.

The Behavioral Health Integration Initiative aims to enhance the health of American Indian and Alaska Native individuals by expanding access to integrated behavioral health care. It supports Tribal and Urban Indian Organization health systems in providing culturally responsive and trauma-informed services. The initiative focuses on improving care coordination, promoting early identification of mental health issues, and integrating various health services to improve overall health outcomes and quality of life for AI/AN communities.

The Colin and Sally Rowell Memorial Scholarship Fund, managed by the Central Kansas Community Foundation, offers financial assistance to graduating seniors from Butler County, KS high schools pursuing higher education or vocational training. This scholarship aims to support students with a demonstrated interest in education or agriculture, emphasizing financial need and potential for success in college. It reflects the foundation's mission to strengthen communities through charitable giving, promoting rural philanthropy in the central Kansas region.

The Clifford and Rubye Angleton Scholarship Fund, managed by the Central Kansas Community Foundation, supports graduating high school seniors and college students from Butler County, Kansas, pursuing higher education. Scholarships are based on available funds and applicants' merit. Recipients may renew their scholarships for up to three years with satisfactory academic progress. This initiative emphasizes the importance of rural philanthropy and aims to empower local students to achieve their educational goals.

The Alpha Delta Kappa Xi Education Scholarship supports graduate students pursuing careers in education. This scholarship aims to recognize and foster fellowship among educators, promoting educational excellence and altruism. By providing financial assistance, it encourages aspiring educators to achieve their goals and contribute to the field of education. Eligible applicants can complete a single online application to match with multiple scholarship opportunities, streamlining the application process.

The Substance Abuse Prevention, Treatment, and Aftercare program aims to combat substance abuse in American Indian and Alaska Native populations. It focuses on enhancing care coordination, expanding culturally competent behavioral health services, and implementing early intervention strategies for at-risk youth. By supporting Tribal and community-led initiatives, the program fosters collaboration among families, youth, and community partners to create effective prevention, treatment, and recovery solutions.

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 300 funds and approximately $80 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Peter V. Westhaysen Medical Education Scholarship

Scholarships are available for post-secondary undergraduate, graduate and post-graduate students pursuing a degree to become a physician or nurse at an accredited university. The purpose of the scholarship is to assist the student with the costs of tuition, fees, and books. The Advisory Committee consider two basic criteria: academic achievement and financial need.

The CNL Charitable Foundation Grants, initiated by CNL Financial Group founder Jim Seneff, aim to enhance community well-being in Central Florida. These grants support 501(c)(3) charities and government institutions, focusing on education, leadership and entrepreneurship, arts and culture, and homelessness and poverty. With a commitment to community transformation, CNL prioritizes organizations that foster broad funding and engage CNL associates, reflecting a dedication to sustainable and impactful philanthropic efforts.

The Rotary Works Foundation Grant supports charitable projects primarily focused on children, youth, and families, emphasizing active Rotarian involvement. Grants range from $500 to $5,000, awarded prior to events. Eligible applicants include 501(c)(3) or 501(c)(1) organizations. Preference is given to projects engaging Rotarians. The application deadline is the 2nd Wednesday of each month, and all grantees must report outcomes post-project.

The National Cancer Institute (NCI) invites applications for studies on mechanisms by which bariatric surgery influences cancer risk. This funding opportunity encourages exploration beyond short-term outcomes like weight loss and diabetes. The goal is to support innovative proof of concept studies, emphasizing feasibility without prior development in the literature. Unpublished data is not allowed, but references from preprints with a DOI are acceptable. Deadlines for applications span from February 2025 to November 2027.

The National Cancer Institute (NCI) is seeking applications for studies that explore how bariatric surgery influences cancer risk, emphasizing the need for innovative research in this area. This funding opportunity encourages the participation of researchers who focus on the long-term impacts of bariatric surgery beyond weight loss and diabetes, addressing critical gaps in understanding the disease mechanisms involved. Key deadlines for application submissions span from February 2025 to October 2027.