Best Large Grants for Nonprofit Organizations in Florida

The Amscot Grant aims to enhance opportunities for Florida's children by supporting local 501(c)(3) organizations. By funding initiatives focused on education, enrichment, and safety, Amscot seeks to empower children and families in communities where it operates. Organizations are encouraged to share their stories and demonstrate how funding will help them create brighter futures. This commitment aligns with Amscot's mission to foster stronger communities across the state.

The Ai2 Predoctoral Young Investigators Program offers predoctoral candidates a unique opportunity to engage in advanced research through collaboration with experienced mentors. Participants can co-author papers and benefit from a generous travel budget, along with support for visa acquisition. This program is designed for candidates preparing to enter a PhD program in the next 1-2 years, providing essential resources and experiences to facilitate their academic journey.

About BlackRock

We’re a global asset manager and technology provider dedicated to helping more and more people experience financial well-being. We help millions of people invest to build savings that serve them throughout their lives. The BlackRock Foundation which funds and partners with organizations that strengthen financial security for more people,

BlackRock Future Builders

BlackRock Future Builders is a $100 million philanthropic initiative funded by The BlackRock Foundation to expand economic opportunity and power the next generation of America’s skilled trades workers. Through this Request for Proposals (RFP) process, The Foundation seeks to support U.S. nonprofit organizations (i.e., registered 501(c)3 organizations) delivering or supporting high‑quality skilled trades training.

This competitive grant opportunity operates in parallel to other BlackRock Future Builders partnerships and is intended to surface additional, regionally grounded solutions across the skilled trades ecosystem. Organizations may propose direct worker training programs or capacity‑building efforts that enable systems to function more effectively and at greater scale. This first round RFP will be administered by Jobs for the Future (JFF), a national nonprofit that transforms U.S. education and workforce systems.

Focus Areas and Solutions

Applicants may propose worker training or capacity‑building solutions aligned to skilled trades workforce development.

• Worker training interventions may include direct service proposals such as pre-apprenticeship or career navigation programs, workforce training programs, apprenticeship programs, or wraparound participant supports that are supportive of training persistence and completion.
• Capacity-building interventions are organizational and system-focused, rather than in direct service of participants, and may include, but are not limited to, proposals such as ecosystem-building, demonstration projects, technology or tool adoptions, or research, among others.

The PLTW Engineering Program Expansion grant, funded by Project Lead The Way Inc, offers $10,000 to public schools in specific districts across several states, including Arkansas, Georgia, and Virginia. This grant aims to enhance existing PLTW Engineering courses or add new ones, alongside teacher training for the 2025-2026 academic year. Grantees are required to submit annual reports and assist in collecting surveys to aid in program improvement and stakeholder engagement.

The PLTW Engineering grant supports public schools in implementing at least one PLTW Engineering course in the 2025-2026 academic year, with a total funding of $30,000 over two years. Eligible districts include those in Arkansas, Georgia, Illinois, Maine, Missouri, North Carolina, Oklahoma, Texas, Virginia, and Wisconsin. Grantees are required to submit annual reports and assist in collecting surveys to enhance program effectiveness and share results with stakeholders.

The Richard S. Reynolds Foundation, established in 1955 in Richmond, Virginia, supports diverse community initiatives in education, healthcare, the arts, and the environment. With over $71 million granted to date, it aims to strengthen communities and foster future generations. The foundation prioritizes requests from IRS-recognized 501(c)(3) organizations while typically avoiding contributions to annual operational costs. Its commitment to impactful projects ensures a lasting positive influence both locally and globally.

Melton Foundation

The Melton Foundation is an international 501(c)(3) non-profit organization registered in the USA, and a leading proponent of Global Citizenship education and practice worldwide. Established nearly thirty years ago with the credence that collaborations across boundaries can forge sustainable solutions to the world’s most pressing challenges, today, our programs reach millions of young leaders, having crystallized into a network of over 750 life-long Melton Fellows spread across 40+ countries. Our primary operations are in Chile, China, Germany, Ghana, India, and the United States of America, with legal subsidiaries in Bangalore, India; Jena, Germany; Temuco, Chile; and Accra, Ghana. 

Through our fellowship and collaborative programs we promote and enable global citizenship as a way for individuals and organizations to work together across boundaries of place and identity to solve challenges in an interconnected world.

Melton Foundation Action Grants

The Melton Foundation offers grants year-round to support Melton Fellows in developing skills, perspective and wider networks to further their capacity as global citizens and contribute towards building an equitable, sustainable, and peaceful world.

In almost 10 years of granting, more than 100 Fellows’ initiatives have been awarded with a Melton Foundation grant to

• Build awareness and/or further awareness raising around global issues and the Sustainable Development Goals (SDGs),
• Develop individual and collective responsibility for sustained, collaborative action,
• Grow capacity to collaboratively drive and sustain social impact at the local and/or global level,
• Further the design, implementation and evaluation of collaborative actions that embody the spirit of global citizenship practice and further social impact, or
• Support coordinated social-impact efforts in a particular or across (emerging) Melton Foundation Hub regions to promote global citizenship practice (s) and the organization’s mission.

The Pittsburgh Foundation

Established in 1945, The Pittsburgh Foundation is one of the nation’s oldest community foundations and as of 2022 is the 18th largest of more than 750 similar foundations across the United States.

As a community foundation, its resources comprise endowment funds established by individuals, businesses and organizations with a passion for charitable giving and fulfilling the Foundation’s mission of improving quality of life for all in the region. The Foundation currently manages about 2,500 individual donor funds and, together with its supporting organizations and its affiliate, The Community Foundation of Westmoreland County, has assets of $1.386 billion (2022). Grantmaking benefits a broad spectrum of basic needs and development opportunities within Pittsburgh and beyond.

Scholarships

The Pittsburgh Foundation and The Community Foundation of Westmoreland County provide scholarship opportunities for local students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four-year universities and career/technical schools.

Daniel R. Miller (Fretts) Memorial Scholarship Fund

The Daniel R. Miller (Fretts) Memorial Scholarship Fund was established to provide scholarship assistance for vocational and higher educational opportunities for Scottdale Borough/East Huntingdon Twp. youth. The fund was endowed by Daniel R. (Bob) Miller’s daughter Karen to honor the memory of her father and the Miller & Fretts families of the Scottdale Area. Bob Miller, for whom this scholarship is named, was born and raised in Scottdale. He believed that the core values instilled in him by his immediate Miller and Fretts relatives in the Scottdale area were a contributing factor to his later successful business career and other lifetime experiences.

The purpose of the scholarship is to provide scholarship assistance to a graduating senior from Southmoreland High School who wishes to pursue a career in a traditional trade or modern equivalent (engineering, architecture, design etc.).

Award Type: Single Year Award. Previous recipients are encouraged to re-apply.

Helen Frankenthaler Foundation

The Helen Frankenthaler Foundation supports the artist’s legacy through a variety of initiatives, including exhibitions, loans of artworks, research and publications, conservation, grants, educational programs for the public and the scholarly community, and the publishing of a catalogue raisonné. It is dedicated to promoting greater public interest in and understanding of the visual arts.

Established and endowed by the artist during her lifetime (1928-2011), the Foundation became active in 2013, on the closing of Frankenthaler’s estate. As the principal beneficiary of Frankenthaler’s estate, the Foundation maintains an extensive collection of her work in a variety of mediums, as well as her collection of works by other artists and original papers and materials pertaining to her life and work.

Frankenthaler Climate Initiative

The Frankenthaler Climate Initiative (FCI) is a pioneering grantmaking program established by the Helen Frankenthaler Foundation. Since its inception in 2021, FCI has distinguished itself as the foremost private national initiative in the United States dedicated to combating climate change specifically within the visual arts sector.

FCI provides visual arts institutions with up to $100,000 to undertake ambitious sustainability and energy efficiency initiatives that directly address carbon reduction and energy efficiency. The scope of its support is broad, encompassing everything from modest, rapid-response projects to comprehensive efficiency audits and feasibility studies, and extending to financial contributions for significant infrastructural renovations and strategic planning for new buildings and major initiatives.

Building on the core values of the Helen Frankenthaler Foundation, the initiative aligns a commitment to environmental stewardship with a belief in the vital importance of the visual arts and arts education. Through strategic funding and partnerships focused on tangible infrastructure, FCI aims to catalyze a sector-wide shift toward zero carbon operations, promoting a future where the visual arts thrive—while contributing to a more sustainable and ecologically conscious world.

Who We Fund

FCI funds nonprofit institutions in the United States and its territories whose primary focus rests in the visual arts. The visual arts includes but is not limited to painting, drawing, sculpture, printmaking, photography, and installations in clay, glass, metal, wood, fiber, paper, film, and mixed media.

Most of our grantees are art museums, nonprofit galleries, archives, noncollecting institutions, art schools, university museums, and artist-endowed foundations.

What We Fund

FCI funds energy efficiency and clean energy generation projects.

FCI meets arts institutions at every stage of the work, through four kinds of grants:

• Catalyst — first actions and stand-alone projects with a quick turnaround
• Scoping — energy audits and assessments that establish a baseline
• Technical Assistance — detailed planning for technically demanding projects
• Implementation — comprehensive capital work addressing a building's environmental impact at multiple levels

Technical Assistance Grants

Technical Assistance grants support projects that have finished initial assessments, and need procurement and financing support for an identified efficiency project. This may include providing designs, specifications, or fees for working with energy services companies (ESCOs) for project support. These grants also support more complex studies or analysis required for pursuing major implementation projects. At the conclusion of a Technical Assistance grant, the applicant should be sufficiently informed to implement a project.

The Oklahoma City Community Foundation administers the Kirschner Trusts, established to honor Phil and Roberta Kirschner's philanthropic legacy. These trusts focus on supporting young individuals with disabilities, Muskogee nonprofits, and Jewish causes. Since their transfer to the foundation in 2013, the trusts have continued to provide vital grants to organizations that align with the Kirschners’ values, ensuring their charitable impact persists in the community.

Honda’s Community Event Sponsorship aims to support local, regional, and national events that enhance community engagement and celebrate diverse cultures. Organizations must be U.S.-based and tax-exempt, focusing on projects that serve communities where Honda associates are active. Eligible events include parades, festivals, and educational initiatives. Honda evaluates requests based on community needs and available funding, reinforcing its commitment to social responsibility and community enhancement.

The Environmental Grantmaking Program at the Educational Foundation of America (EFA) aims to support projects that facilitate a transition to a net-zero electricity system. Focused on reducing greenhouse gas emissions, the program emphasizes initiatives that enhance access to affordable clean energy, accelerate regional transitions, and strengthen financial investment in electric utilities. Eligible applicants include 501(c)3 public charities, academic institutions, and government entities committed to sustainable energy solutions.

Citizen Security Research Initiative

IPA's Citizen Security Research Initiative (CSRI) supports rigorous impact evaluations, pilot studies, infrastructure and public goods projects, and foundational and contextual research to inform policies and programs on building safer communities and strengthening justice and law enforcement systems. Funding for CSRI comes from the United States Department of State's Bureau of International Narcotics and Law Enforcement Affairs (INL).

Supported projects will generate actionable evidence to inform policy and programming in the citizen security and justice sector, with a focus on studies that challenge common beliefs, pioneer innovative interventions, and produce evidence where little currently exists. Priority areas of research include:

• Countering organized crime
• Combating drug trafficking and production
• Preventing crime and violence
• Strengthening law enforcement and criminal justice institutions

Budgets are expected to adhere to the budget caps outlined in our Call for Proposals (US$75,000 for pilots, US$400,000 for full impact evaluation studies, US$250,000 for infrastructure and public goods creation projects, US$75,000 for foundational and contextual research projects). In recognition that research in some locations or with some populations is more costly, on a case-by-case basis, we will consider budgets over the above award maximums with appropriate justification.

Awards are normally paid on a cost-reimbursable basis.

About Us

We are a philanthropic organization committed to catalyzing the impact of social entrepreneurs who are expanding access and opportunity in America. 

At New Profit, we partner with social innovators, philanthropists, and other impact leaders who are creating a more inclusive and prosperous America. We invest in and support leaders and organizations that are transforming our education, economic, and democratic systems. And we are guided by the belief that those who are most proximate to the communities we serve are the best positioned to develop effective and sustainable solutions.

We seek and support leaders and organizations with scalable solutions that match the size of the problems we face and expansive visions that match the scale of our ambitions for America.

Connected Futures Cohort Grant

New Profit is launching Connected Futures, a Catalyze cohort for organizations that bridge divides and bring people together to solve problems collectively. Submit a Discovery Form to signal your interest and to be considered to submit an application for this funding cycle. 

New Profit’s Catalyze cohorts support innovative social impact organizations expanding access and opportunity in America. This model brings together cohorts of organizations with similar focus areas and stages, providing each with a one-year $100,000 unrestricted grant, a $10,000 grant for leadership development, and strategic advisory support.

Social Entrepreneurs* participate in a year-long cohort experience designed to build community, facilitate peer learning, and provide capacity-building support, including workshops on topics such as board development, fundraising, scenario planning, and storytelling. 

About Connected Futures

Connected Futures is a new Catalyze cohort for organizations that help people move across active divides to take action toward common goals. We are looking for organizations that build trust, strengthen collaboration, and create ways for people to act together when mistrust, polarization, exclusion, or disconnection would otherwise keep them apart and prevent them from solving problems together.

These organizations may work in the health, economic mobility, democracy, and/or education sectors. What connects them is not a single issue area, but a common approach to bridgebuilding: creating the relationships, skills, and structures people need to work together toward positive change.

Catalyze cohorts are at their best when cohort members are fully engaged. The Social Entrepreneurs that lead selected organizations are expected to participate in the Catalyze support model and peer learning community in the following ways:

• Social Entrepreneurs attend three in-person convenings, each of which are held over 3-4 days in cities across the United States. Convening dates for this cohort will be shared with organizations invited to complete a full application.
• Social Entrepreneurs attend three virtual learning sessions, each lasting 2-3 hours. Webinar dates for this cohort will be shared with organizations invited to complete a full application.
• Social Entrepreneurs engage with the New Profit team via 1:1 strategic advising, including a minimum of six virtual sessions over the yearlong cohort.
• Entrepreneurs receive a $10,000 stipend specifically to support their own leadership development goals.
• Programming requires a commitment of 6-8 hours per month on average. New Profit covers the cost of travel, accommodation, and meal expenses for each in-person convening.

J.B. Hunt Transport Services offers financial support for various community projects through its Company Giving program. Focused on four key areas—Health Care, Veterans' Support, Education, and Crisis Management—this initiative aims to enhance the well-being of local communities. Eligible applicants include 501(c)(3) organizations, schools, and civic groups, while organizations that primarily benefit their members or have high management overhead may be excluded. The program underscores J.B. Hunt's commitment to corporate social responsibility.

The Kenneth Rainin Foundation seeks to promote innovative research in Inflammatory Bowel Disease (IBD) by encouraging diverse perspectives from early career investigators and those underrepresented in science. The Innovator Awards do not require preliminary data and are evaluated based on the potential for innovation and scientific merit. Eligible researchers must hold advanced degrees and can apply for funding through their home institutions, fostering groundbreaking ideas that can transform IBD treatment and prevention.

The AAO-HNSF Percy Memorial Research Award offers $25,000 for one year to support innovative research projects in otolaryngology-head and neck surgery. This grant aims to fund projects with clinical significance, encouraging the development of new long-term research initiatives. Applicants must submit a detailed budget and secure letters of support from their Department Chair and key personnel involved in the project. Funds cannot cover salaries or purchase equipment exceeding $500.

The Atmospheric and Geospace Sciences Postdoctoral Research Fellowships (AGS-PRF) support early career researchers conducting independent studies in diverse areas such as Atmospheric Chemistry and Space Weather Research. These fellowships, lasting up to 24 months, aim to enhance the research capabilities of promising individuals while fostering interdisciplinary collaboration and leadership within the scientific community. AGS encourages applications from diverse backgrounds to promote inclusivity and equity in geoscience.

The Steel Dynamics Foundation Grant focuses on enhancing community quality of life and local economies by supporting 501(c)(3) nonprofit organizations. Priorities include higher education, economic development, and human services, particularly in communities where Steel Dynamics operates. Grants are awarded based on community impact, employee involvement, and organizational integrity. Applicants must demonstrate a strong ethical track record and effective community engagement to qualify for funding opportunities.

The Northrop Grumman Corporation Graduate Education Scholarship, part of the Graduate Education Fund, supports Australian students pursuing graduate-level studies in the USA. Offering up to $40,000 for one year, it is aimed at fields such as Artificial Intelligence, Quantum Physics, and Aerospace Engineering. Eligible candidates must be Australian citizens or permanent residents and have a formal offer from an accredited American institution. This scholarship promotes academic exchange and fosters international collaboration in specialized disciplines.

The Cyrus M. Quigley Foundation Grant supports tax-exempt organizations that empower young people through initiatives focusing on courage, self-reliance, and service. Since its inception in 1993, the foundation has awarded over $300,000 in grants, with amounts ranging from $1,000 to $7,500. The foundation emphasizes physical challenges and community service to help develop essential life skills. Grant proposals are accepted annually until the third Friday in April, with decisions communicated by May 31.

The Park Foundation Grants for the Environment focus on ensuring clean and accessible drinking water while opposing shale gas extraction and infrastructure expansion. They fund diverse initiatives aimed at promoting sustainable practices and policies, particularly within New York State. The Foundation supports advocacy, organizing, and corporate responsibility efforts that align with their mission to foster a just and sustainable environment, empowering communities to protect their natural resources.

The Laura Bush 21st Century Librarian Program aims to enhance the library and archival workforce by addressing community information needs and strengthening institutional capacities. It supports innovative projects that explore alternative pathways into library services, advance continuing education, and foster recruitment and retention of future professionals. By focusing on diverse training and development, the program seeks to cultivate a new generation of library leaders equipped to meet evolving challenges.

The Sparkplug Foundation Grant supports innovative projects from early-stage organizations and established non-profits in education, community organizing, and music. The foundation emphasizes community-led initiatives that address systemic injustices and engage marginalized populations. Grants are available for one year and prioritize projects with small budgets that lack extensive funding sources. The foundation encourages applications from diverse communities, particularly those led by Black, Indigenous, People of Color, and LGBTQ individuals, fostering equitable access to resources.

The CAPTRUST Community Foundation provides Crisis Grants to support nonprofit organizations aiding families impacted by natural disasters or emergencies. By dedicating over 10% of its annual budget for crisis assistance, the foundation ensures that funds directly benefit those in need. Grants can be requested up to $5,000 to help rebuild lives during challenging times, reflecting the foundation's commitment to integrity and support for children and families in crisis.

The Turtle Trackers - Linda Zambelli Family Scholarship Fund, established in 2025 by the Turtle Trackers Board, honors Linda Zambelli's legacy through scholarships for students pursuing higher education in Marine Biology and Environmental Sciences. This initiative supports high school seniors from Beaufort and Jasper Counties, ensuring they have opportunities to excel academically while fostering a commitment to marine conservation. The fund is managed by the Community Foundation of the Lowcountry, which has invested over $125 million in local communities.

The Prof. Rahamimoff Travel Grants for Young Scientists support PhD students in research requiring expertise unavailable in their home countries. Named after renowned scientist Prof. Rami Rahamimoff, the grants fund trips to higher education or research facilities in the U.S. or Israel, lasting up to two months. Eligible applicants must be U.S. or Israeli citizens conducting supervised research at accredited institutions. This program honors Prof. Rahamimoff's legacy in science and medicine.