Best Large Grants for Nonprofit Organizations in Florida

The CLIMB Near Peer Mentorship Program by John Muir Health offers a year-long mentorship initiative aimed at developing family medicine learners into community-engaged providers. This program supports high school, undergraduate, and medical students by pairing them with mentors in the healthcare field. Participants engage in weekly virtual meetings and receive guidance throughout their educational journey, fostering a diverse and inclusive future in healthcare professions.

Community Foundation of Northwest Mississippi

The Community Foundation of Northwest Mississippi manages 314 donor-established funds and has disbursed over $48 million to support more than 1,000 charitable organizations and activities recommended by its donors, as well as charitable programs established by the foundation. Established in 2002 with a generous grant from the Maddox Foundation, the Community Foundation is an independent 501(c)3 charitable organization. The Foundation serves Bolivar, Coahoma, DeSoto, Leflore, Marshall, Panola, Quitman, Sunflower, Tallahatchie, Tate, Tunica and Yalobusha counties. 

The Reese and Joelle Norris Service through Music Scholarship

The Community Foundation, CoroRio, and MidSouth Music Institute is pleased to offer a $500 college scholarship: The Reese and Joelle Norris Service through Music Scholarship. We are grateful to Reese and Joelle Norris for more than ten years of service to CoroRio and the MidSouth Music Institute. Together, they have nearly 50 years of teaching thousands of all ages throughout the MidSouth and across the country.

Starting in the Spring of 2024, the scholarship will be awarded each year to a student who is currently involved in CoroRio, plans to pursue a career related to music, and has demonstrated a passion for serving others through music, like Reese and Joelle. 

The Jacquilyn Billey Memorial Scholarship, offered by the National Federation of the Blind, provides thirty merit-based scholarships of $10,000 each to legally blind students pursuing post-secondary education in the U.S. The scholarship emphasizes academic excellence, community service, and leadership. Finalists are selected in spring and must attend the NFB National Convention in July for the award announcement. This initiative empowers blind individuals to pursue their educational and career aspirations, reflecting a commitment to inclusivity and opportunity.

The Affiliate Grants - Early Music Program Fund supports educational initiatives for AMS-affiliated groups focusing on music and culture from before 1600. Established in 2020, it enhances research skills through various programming, including paleography and organology. Eligible applicants are limited to AMS chapters, study groups, and committees, with funding capped at $2000. The program aims to strengthen scholarly networks and requires grant reporting on fund usage and impact.

The Emma Jean Frierson Memorial Nursing Scholarship, offered by the Saginaw Community Foundation, supports Michigan residents pursuing an undergraduate degree or vocational training in nursing. This scholarship honors Emma Jean Frierson, a dedicated LPN and nursing program graduate who positively impacted her community. With awards ranging from $500 to $4,000, the scholarship aims to help students in financial need access quality education in nursing, a vital field with growing demand.

The CFSLC Small Grant by the Community Foundation of South Lake County aims to enhance community welfare by supporting nonprofit organizations that serve the residents of the former South Lake County tax district. Eligible applicants must be IRS-recognized 501(c)(3) entities with a budget not exceeding $3 million and a commitment to sustainability. The grant focuses on connecting resources, empowering local initiatives, and fostering lasting impact in Clermont, Groveland, Mascotte, Minneola, and Montverde.

About

Our Strong Community Framework — the first-ever philanthropic vision for the Adirondack region — guides our approach to investing in promising opportunities across our five "whole community" focus areas. In partnership with generous donors and capable nonprofits, we bring all the tools of a community foundation to bear to meet today's pressing needs and build charitable resources for the needs of tomorrow. 

Scholarships

What could be more important for the future of the Adirondack region than to educate our children? As one of five key interest areas for what we fund, creating educational pathways helps to ensure all students in the Adirondacks have meaningful opportunities to pursue post-secondary education, career training, and pathways to gainful employment and fulfilling lives. Scholarships can play a pivotal role in helping students better themselves, no matter their life stage or path.

Scholarship funds at Adirondack Community Foundation have been created to benefit specific educational institutions or fields of study. The most common way we distribute scholarships is in partnership with schools across our region that manage scholarship committees that select recipients based on guidelines set forth by fundholders. We also have some scholarship funds to which students can apply directly for support. All scholarship funds use a competitive application process to make decisions.

Sean P. McCullough Memorial Scholarship

The Sean P. McCullough Memorial Scholarship Fund was named after Sean McCullough, a Plattsburgh High School senior who died tragically on May 14, 2005. Learn more about Sean here or watch the video above.

The scholarship supports outstanding graduating seniors from any New York State Section VII high school that plans to continue their education at the college level. Students must be a member of the school track team, embody school spirit, demonstrate academic strength, dedication, competitive spirit, and good leadership skills.

There is no student application for this scholarship. Students must be nominated by their track coach.

Scholarship amounts are up to $1,750.

Geographic Focus

New York State Section VII schools

The Colonel David Marcus Memorial Scholarship Award supports students from Burlington, Camden, or Gloucester Counties pursuing post-high school education, particularly in military programs. Established by the Jewish Community Foundation, this scholarship prioritizes candidates who embody Col. Marcus's ideals. Eligible applicants must be high school seniors and may apply for multiple awards. The fund has a strong community leadership background, managing over $35 million in assets to support educational initiatives.

The Cromwell High School Alumni Scholarship Fund provides a one-time award of $1,000 for West Noble High School seniors residing in Sparta Township. Eligible applicants must plan to attend accredited higher education institutions or vocational training programs. Established by the Cromwell High School Alumni Committee in 2016, the fund aims to support students in pursuing their educational goals while honoring the values and memories associated with their alma mater.

The Amyloidosis Fund, managed by the HealthWell Foundation, provides essential financial assistance to underinsured patients facing treatment costs for Amyloidosis. The program covers prescription copays, insurance premiums, and related expenses, ensuring that patients can access necessary medications without financial strain. With a maximum award of $8,000, the fund aims to alleviate the burden of healthcare costs for those diagnosed with this complex disease, promoting better health outcomes and quality of life for patients across the United States.

The Vascular Care for the Underserved Project Grants, funded by the Society for Vascular Surgery Foundation, aim to address disparities in vascular care for women. With a grant of $20,000, this initiative focuses on enhancing access, inclusion, and gender-specific research in vascular health. It supports innovative projects that aim to improve care delivery to underserved women and ensure equitable representation in vascular research, ultimately aiming to advance health outcomes and address historical exclusions in clinical studies.

The Book Buddies Program, initiated by The Molina Foundation, aims to combat the lack of access to books in low-income communities. By distributing new, free books to eligible schools and agencies, the program fosters literacy and learning among children. With over 4 million books distributed, it helps create word-rich environments essential for educational success. This initiative supports families in building home libraries and enhances learning spaces, ensuring children have the resources they need to thrive.

The Altrusa Club of Wenatchee Scholarship supports female graduates of Wenatchee Valley College pursuing further education. Funded by the Community Foundation of NCW, this scholarship aims to empower women through financial assistance based on need and academic merit. Eligible recipients must maintain a minimum GPA of 2.0 and demonstrate commitment to their educational goals. This initiative reflects the club's dedication to promoting women's education and ensuring their successful transition to higher learning institutions.

The AHA Institutional Research Enhancement Award (AIREA) aims to bolster cardiovascular and brain health research at smaller educational institutions that lack significant NIH funding. With a budget of $100,000 annually over two years, the award supports various research areas, encourages student involvement, and strengthens institutional research environments. Eligible applicants include accredited U.S. non-profit institutions with specific funding limitations, ensuring that deserving projects receive vital support for advancing health-related research.

The What’s Your Gap Grant, provided by BreatheStrong CF in partnership with the Closing the Gap Foundation, supports teens and adults living with cystic fibrosis. This grant alleviates financial barriers, allowing recipients to pursue health and wellness opportunities tailored to their individual goals. It aims to empower applicants who envision a healthier lifestyle but face challenges in achieving it, serving as a catalyst for positive change in their lives.

Cumberland Community Foundation ("CCF") manages more than 60 scholarship endowment funds created by local individuals, families, civic organizations, and corporations who want to provide a path to higher education for future generations. 

Each year, Cumberland Community Foundation announces more than $1,000,000 in college scholarships to students from southeastern North Carolina.

Fayetteville Firefighters Scholarship

Must be both an active uniform Fayetteville firefighter and planning to attend accredited college/university within 6 months.

The Paul Drury Memorial Scholarship honors the legacy of Paul Drury, who inspired many while living with cystic fibrosis. This scholarship is aimed at siblings and children of individuals with CF, recognizing the crucial support family members provide. Eligible applicants must have a family member with CF, demonstrate academic achievement, and be enrolled in an educational program. This initiative highlights the importance of family in managing the challenges posed by cystic fibrosis.

We administer a number of scholarships, which range from the traditional academic and athletic awards to corporate and special circumstances offerings. Applying for a scholarship is free, so we invite you to spend some time finding opportunities for which you are a good fit.

Ounce of Prevention Scholarship Fund

The purpose of the fund is to provide one or more annual scholarships to graduates of an accredited high school located in Marshall County, Indiana.  

Recipients must be a survivor of cancer, have an immediate family member or friend who experienced cancer, or have demonstrated active participation in community service related to the prevention or cure of cancer.

Cumberland Community Foundation ("CCF") manages more than 60 scholarship endowment funds created by local individuals, families, civic organizations, and corporations who want to provide a path to higher education for future generations. 

Each year, Cumberland Community Foundation announces more than $1,000,000 in college scholarships to students from southeastern North Carolina.

Paul & Frances Monroe Music Scholarship Award

Rising sophomore, junior, or senior; Graduated from a high school in Cumberland, Richmond, Robeson, or Scotland County.

The Rooted Pathways Program, initiated by First Peoples Fund, offers essential support to Native-led arts organizations, fostering their growth and stability. This funding empowers these organizations to thrive in their missions, providing unrestricted operating support and participation in a Learning Cohort. Eligible applicants include Native nonprofits and collectives with budgets under $500,000, and the program aims to uplift artists from U.S. federally recognized tribes. This initiative is part of the Wallace Foundation's broader commitment to enhancing well-being in the arts.

The Women’s Service League of North Central Washington Scholarship, established in 2013, aims to support female students from various high schools in the region. This scholarship prioritizes applicants who demonstrate community involvement, leadership skills, and a minimum GPA of 2.75. Special consideration is given to those who have faced significant challenges and to children or grandchildren of League members, fostering a commitment to volunteerism and community improvement.

The Vanderpool Scholarship Fund, managed by the Manatee Community Foundation, offers financial support for residents of Manatee County pursuing vocational training in medical and health-related fields. This scholarship emphasizes academic excellence, community involvement, and career aspirations. With over 25 years of commitment to philanthropy, the Foundation aims to enhance the quality of life in the community through informed giving and partnerships with various local organizations.

The Craig Zadan Pathway for Equity in the Arts Grant aims to enhance high school theatre programs in underserved communities. By providing $10,000 grants, this initiative fosters collaboration between students and industry professionals, while promoting performances that address diverse perspectives. The grant encourages schools to select plays that spark important conversations, ensuring inclusivity and representation in the arts. Ultimately, it seeks to inspire students and open doors to future careers in theatre.

2026-27 Innovative Service Development (ISD) Grant Opportunity

The Florida Commission for the Transportation Disadvantaged is pleased to announce the release of the Innovative Service Development (ISD) Grant Program application package for Fiscal Year 2026–2027.

This is a competitive grant program for Community Transportation Coordinators and Non-Traditional Transportation Service Providers. Anticipated total available funding is $6 million, contingent upon legislative authority and Governor’s approval.

This funding opportunity supports projects that test new transportation services that improve the cost-effectiveness, efficiency, and accessibility of transportation services for transportation disadvantaged individuals.

Introduction

The Transportation Disadvantaged Trust Fund is administered by the Florida Commission for the Transportation Disadvantaged (CTD) in accordance with Section 427.0159, Florida Statutes (F.S.). The Trust Fund provides a dedicated funding source to support the Commission’s statutory responsibilities and is appropriated annually by the Legislature for the state fiscal year (July–June).

For Fiscal Year 2026–2027, the Commission anticipates a $6 million appropriation to support the Innovative Service Development (ISD) Grant Program.

The ISD Grant Program supports projects that improve the cost-effectiveness and efficiency of transportation services. Grant funds are limited to reimbursing a portion of eligible transportation disadvantaged passenger trips. Grantees must provide services prior to submitting invoices for reimbursement, which will be issued on a per-trip and/or mileage basis.

Funded projects may include, but are not limited to:

• Expanding service availability (e.g., evenings, weekends or level of service)
• Serving currently underserved populations
• Enhancing regional or cross-county mobility
• Reducing barriers to accessing public transportation 

The Kenneth Jernigan Scholarship, offered by the National Federation of the Blind, honors the legacy of Jacquilyn Billey, a dedicated advocate for the blind. With thirty merit-based scholarships of $10,000 each available, applicants must be legally blind, reside in the U.S., and plan to pursue full-time post-secondary education. Awards are based on academic excellence, community service, and leadership, with finalists attending the NFB National Convention in July for selection.

The Intervention Research to Improve Native American Health initiative aims to enhance health outcomes in Native American communities through innovative research. This program supports studies focused on health promotion, disease prevention, and culturally informed treatment strategies. Key deadlines for grant applications are October 21, 2025, and January 7, 2026. By addressing health disparities and leveraging community strengths, the initiative fosters sustainable interventions tailored to specific cultural contexts.

The Gardner, Prudence E. Memorial Scholarship Fund, managed by the Noble County Community Foundation, supports West Noble High School seniors with a GPA between 3.00 and 3.50. To qualify, applicants must demonstrate a strong work ethic through part-time employment or active participation in extracurricular activities. This scholarship aims to encourage students to excel academically while contributing positively to their communities, furthering the foundation's mission of fostering positive change in Noble County.